Topological methods improve neuron analysis and tracer injection summary.
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Novel 'strong neuron' improves deep learning efficiency and robustness.
This paper presents a new artificial neuron model capable of learning its receptive field in the topological domain of inputs. The model provides adaptive and differentiable local connectivity (plasticity) applicable to any domain. It requires no other tool than the backpropagation algorithm to learn its parameters whi…
Dynamics and function of neuronal networks are determined by their synaptic connectivity. Current experimental methods to analyze synaptic network structure on the cellular level, however, cover only small fractions of functional neuronal circuits, typically without a simultaneous record of neuronal spiking activity. H…
To understand how rich dynamics emerge in neural populations, we require models exhibiting a wide range of activity patterns while remaining interpretable in terms of connectivity and single-neuron dynamics. However, it has been challenging to fit such mechanistic spiking networks at the single neuron scale to empirica…
"Sparse" neural networks, in which relatively few neurons or connections are active, are common in both machine learning and neuroscience. Whereas in machine learning, "sparsity" is related to a penalty term that leads to some connecting weights becoming small or zero, in biological brains, sparsity is often created wh…
Proposes neuron alignment to optimize mode connectivity in neural networks.
Neural circuits contain heterogeneous groups of neurons that differ in type, location, connectivity, and basic response properties. However, traditional methods for dimensionality reduction and clustering are ill-suited to recovering the structure underlying the organization of neural circuits. In particular, they do n…
Estimates neuronal connectivity from spike times using flexible Hawkes processes.
AKOrN uses synchronized neurons to improve AI tasks.
Modeling hidden neurons in SNNs using mesoscopic approximations.
Improved NiNo networks accelerate Adam training by up to 50%.
Paper improves neural interaction modeling using nonlinear Hawkes processes.
Efficiently estimates neural connectivity using ensemble stimulation.
One of the main difficulties in analyzing neural networks is the non-convexity of the loss function which may have many bad local minima. In this paper, we study the landscape of neural networks for binary classification tasks. Under mild assumptions, we prove that after adding one special neuron with a skip connection…
Simplified neural network EFTs reveal a single critical condition.
In this work, we investigate the use of three information-theoretic quantities -- entropy, mutual information with the class variable, and a class selectivity measure based on Kullback-Leibler divergence -- to understand and study the behavior of already trained fully-connected feed-forward neural networks. We analyze …
Understanding the morphological changes of primary neuronal cells induced by chemical compounds is essential for drug discovery. Using the data from a single high-throughput imaging assay, a classification model for predicting the biological activity of candidate compounds was introduced. The image recognition model wh…
The optimization of multilayer neural networks typically leads to a solution with zero training error, yet the landscape can exhibit spurious local minima and the minima can be disconnected. In this paper, we shed light on this phenomenon: we show that the combination of stochastic gradient descent (SGD) and over-param…
We introduce bio-inspired artificial neural networks consisting of neurons that are additionally characterized by spatial positions. To simulate properties of biological systems we add the costs penalizing long connections and the proximity of neurons in a two-dimensional space. Our experiments show that in the case wh…
Deep Heaviside networks are limited but can be improved with connections or linear neurons.
Recently, it has been shown that spiking neural networks (SNNs) can be trained efficiently, in a supervised manner, using backpropagation through time. Indeed, the most commonly used spiking neuron model, the leaky integrate-and-fire neuron, obeys a differential equation which can be approximated using discrete time st…
Unseen or out-of-domain data can seriously degrade the performance of a neural network model, indicating the model's failure to generalize to unseen data. Neural net pruning can not only help to reduce a model's size but can improve the model's generalization capacity as well. Pruning approaches look for low-salient ne…
Capsules are the multidimensional analogue to scalar neurons in neural networks, and because they are multidimensional, much more complex routing schemes can be used to pass information forward through the network than what can be used in traditional neural networks. This work treats capsules as collections of neurons …
In the wake of recent advances in experimental methods in neuroscience, the ability to record in-vivo neuronal activity from awake animals has become feasible. The availability of such rich and detailed physiological measurements calls for the development of advanced data analysis tools, as commonly used techniques do …
Neuronal circuits formed in the brain are complex with intricate connection patterns. Such complexity is also observed in the retina as a relatively simple neuronal circuit. A retinal ganglion cell receives excitatory inputs from neurons in previous layers as driving forces to fire spikes. Analytical methods are requir…
Information in neural networks is represented as weighted connections, or synapses, between neurons. This poses a problem as the primary computational bottleneck for neural networks is the vector-matrix multiply when inputs are multiplied by the neural network weights. Conventional processing architectures are not well…
New method estimates neuronal connectivity from partially observed data.
Efficiently learns a single neuron with adversarial noise, improving on prior work.
Neural connectomics has begun producing massive amounts of data, necessitating new analysis methods to discover the biological and computational structure. It has long been assumed that discovering neuron types and their relation to microcircuitry is crucial to understanding neural function. Here we developed a nonpara…
Recently, we proposed to transform the outputs of each hidden neuron in a multi-layer perceptron network to have zero output and zero slope on average, and use separate shortcut connections to model the linear dependencies instead. We continue the work by firstly introducing a third transformation to normalize the scal…
Improves conditions for mode connectivity in deep neural networks.
New metric captures individual neuron tuning across neural networks.
Studying neural connectivity is considered one of the most promising and challenging areas of modern neuroscience. The underpinnings of cognition are hidden in the way neurons interact with each other. However, our experimental methods of studying real neural connections at a microscopic level are still arduous and cos…
DNN pruning reduces memory footprint and computational work of DNN-based solutions to improve performance and energy-efficiency. An effective pruning scheme should be able to systematically remove connections and/or neurons that are unnecessary or redundant, reducing the DNN size without any loss in accuracy. In this p…
Recently, a lot of techniques were developed to sparsify the weights of neural networks and to remove networks' structure units, e.g. neurons. We adjust the existing sparsification approaches to the gated recurrent architectures. Specifically, in addition to the sparsification of weights and neurons, we propose sparsif…
Law derived for neural networks with sparse connections.
Probabilistic bounds on neuron death in deep networks, showing depth can be increased indefinitely.
This paper improves model fusion by training-time neuron alignment, reducing barriers in multi-model fusion.
Knowledge of functional groupings of neurons can shed light on structures of neural circuits and is valuable in many types of neuroimaging studies. However, accurately determining which neurons carry out similar neurological tasks via controlled experiments is both labor-intensive and prohibitively expensive on a large…
Recent work suggests goal-driven training of neural networks can be used to model neural activity in the brain. While response properties of neurons in artificial neural networks bear similarities to those in the brain, the network architectures are often constrained to be different. Here we ask if a neural network can…
Neurons and networks in the cerebral cortex must operate reliably despite multiple sources of noise. To evaluate the impact of both input and output noise, we determine the robustness of single-neuron stimulus selective responses, as well as the robustness of attractor states of networks of neurons performing memory ta…
Neuroscientific theory suggests that dopaminergic neurons broadcast global reward prediction errors to large areas of the brain influencing the synaptic plasticity of the neurons in those regions. We build on this theory to propose a multi-agent learning framework with spiking neurons in the generalized linear model (G…
The study quantifies geometric differences between axonal branches using splines.
This paper presents a Bayesian approach to learning the connectivity structure of a group of neurons from data on configuration frequencies. A major objective of the research is to provide statistical tools for detecting changes in firing patterns with changing stimuli. Our framework is not restricted to the well-under…
The loss of a few neurons in a brain rarely results in any visible loss of function. However, the insight into what "few" means in this context is unclear. How many random neuron failures will it take to lead to a visible loss of function? In this paper, we address the fundamental question of the impact of the crash of…
EP learns like BPTT but with local weight updates.
New methods estimate brain connectivity from calcium imaging data with missing data.