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arXiv research

A locally-built, LLM-digested index of recent arXiv papers in quant finance, geometry/topology, and statistical ML — keyword search served straight from SQLite on this machine.

168,742 papers · 148 categories

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48 results for neurological diseases

Study uses GMM-UBM and i-vectors to assess Parkinson's patients via speech, handwriting, and gait.

problem Assessing neurological state of Parkinson's disease patients using speech, handwriting, and gait signals.
method GMM-UBM and i-vectors applied to speech, handwriting, and gait signals.
result Different feature sets from each signal are crucial for assessing Parkinson's patients.

Paper uses TDA for automated Parkinson's disease classification and severity assessment.

problem Manual diagnosis of neurological diseases is time-consuming and inaccurate.
method Combines Topological Data Analysis (TDA) with machine learning on postural shift data.
result Proposes a stable and accurate method for classifying Parkinson's disease.

Sparse GFA identifies disease factors in FTD subgroups.

problem Heterogeneity in neurological disorders hinders understanding and treatment.
method Sparse Group Factor Analysis (GFA) with regularised horseshoe priors.
result Identified latent disease factors differentially expressed in FTD subgroups.

Improves disease progression prediction using auxiliary surrogate labels and health markers.

problem Challenges in predicting disease progression due to unknown true disease states.
method Integrates hidden Markov model with time-varying discriminative classification model.
result Significant improvement in distinguishing LBD from AD using objective markers.

Case vs control comparisons have been the classical approach to the study of neurological diseases. However, most patients will not fall cleanly into either group. Instead, clinicians will typically find patients that cannot be classified as having clearly progressed into the disease state. For those subjects, very lit…

2012-07-19abs ↗pdf ↗

This study evaluates handwriting features to diagnose Parkinson's disease.

problem Diagnosing Parkinson's disease through handwriting analysis.
method Kinematic, geometrical, and non-linear features were evaluated using K-nearest neighbors, support vector machines, and random forest classifiers.
result Up to 93.1% accuracy in classifying Parkinson's disease and healthy subjects.

Epilepsy is a neurological disorder classified as the second most serious neurological disease known to humanity, after stroke. Localization of the epileptogenic zone is an important step for epileptic patient treatment, which starts with epileptic spike detection. The common practice for spike detection of brain signa…

2019-07-03abs ↗pdf ↗

Drawing an inspiration from behavioral studies of human decision making, we propose here a general parametric framework for a reinforcement learning problem, which extends the standard Q-learning approach to incorporate a two-stream framework of reward processing with biases biologically associated with several neurolo…

2019-06-21abs ↗pdf ↗

Study builds models to predict post-cardiac arrest outcomes using patient data.

problem Lack of accurate prognostication methods for patients resuscitated from cardiac arrest.
method Integrated electronic health records (EHR) and physiological time series (PTS) data to train machine learning classifiers.
result Combined EHR-PTS24 models outperformed models using either EHR or PTS24 alone in predicting survival and neurological outcomes.

WISDoM uses the Wishart distribution to analyze neurological data like EEG and brain connectivity.

problem Characterizing deviations of covariance or correlation matrices from expected values.
method WISDoM framework for quantifying deviations from the Wishart distribution.
result Validated on EEG feature ranking and classification of autism subjects.

NeuroQuery synthesizes brain mapping evidence across diverse concepts.

problem Lack of comprehensive meta-analysis of human brain mapping across different mental processes and mechanisms.
method A multivariate model that predicts the spatial distribution of neurological observations given text describing an experiment, cognitive process, or disease.
result Captures relationships and neural correlates of 7,547 neuroscience terms across 13,459 neuroimaging publications.

DVNet efficiently segments large neurovascular datasets using skip connections.

problem Challenges in segmenting large neurovascular datasets from high-throughput microscopy data.
method A fully-convolutional, deep, and densely-connected encoder-decoder network with skip connections.
result DVNet achieves superior performance in semantic segmentation of neurovascular datasets.

Resource-efficient oblique trees reduce neural signal classification costs.

problem Implementing efficient neural signal classifiers on resource-constrained devices.
method Integrating model compression, probabilistic routing, and cost-aware learning.
result Significant reduction in model size and feature extraction cost compared to state-of-the-art models.

The study quantifies geometric differences between axonal branches using splines.

problem Neuromorphology's focus on macroscopic features neglects neuron internal geometry.
method Fitting splines to neuron traces, using Frenet-Serret formulas to compute curvature and torsion.
result Parameters of curvature and torsion are distributed differently between axonal branches.

AI enhances personalized drug development and decision-making in pharma.

problem Traditional drug development lacks personalized treatment plans.
method Application of AI in drug discovery, clinical trials, and post-marketing assessment.
result AI improves personalized medicine, optimizing health outcomes.

Biological and social systems consist of myriad interacting units. The interactions can be represented in the form of a graph or network. Measurements of these graphs can reveal the underlying structure of these interactions, which provides insight into the systems that generated the graphs. Moreover, in applications s…

2014-11-08abs ↗pdf ↗

R-PLS improves analysis of brain functional connectivity matrices.

problem Improving analysis of functional connectivity matrices in brain imaging.
method Introducing R-PLS, a generalization of PLS for symmetric positive definite matrices.
result R-PLS identifies key functional connections in brain imaging datasets.

New algorithm extracts shared latent space for cortico-muscular interactions.

problem Challenges of high dimensionality and limited sample sizes in multivariate cortico-muscular analysis.
method Structured and sparse partial least squares coherence (ssPLSC) algorithm.
result ssPLSC achieves competitive or better performance in scenarios with limited sample sizes and high noise levels.

Disease phenotyping algorithms process observational clinical data to identify patients with specific diseases. Supervised phenotyping methods require significant quantities of expert-labeled data, while unsupervised methods may learn non-disease phenotypes. To address these limitations, we propose the Semi-Supervised …

2018-12-07abs ↗pdf ↗

Bayesian meta-learning predicts Alzheimer's disease progression.

problem Predicting individual Alzheimer's disease progression from limited data.
method Bayesian meta-learning approach that dynamically predicts disease score distributions.
result Bayesian meta-learner outperforms single-task models and deterministic meta-learners, especially for long-term predictions.

Deep Belief Network predicts lncRNA-disease associations with high accuracy.

problem Accurately identifying lncRNA-disease associations to understand lncRNA functionality and disease mechanism.
method Proposes a DBN-based model using heterogeneous networks and DBN for feature learning.
result Obtained AUC of 0.96 and AUPR of 0.967 on standard dataset.

Enhances disease progression modeling using LLMs for complex brain connectivity.

problem Inaccurate predictions of disease spread due to oversimplified brain connectivity models.
method Uses LLMs to synthesize multi-modal relationships and learn disease trajectories from longitudinal data.
result Superior prediction accuracy and interpretability compared to traditional methods.