A locally-built, LLM-digested index of recent arXiv papers in quant finance, geometry/topology, and statistical ML — keyword search served straight from SQLite on this machine.
Network medicine predicts repurposable drugs for COVID-19.
In medicine, visualizing chromosomes is important for medical diagnostics, drug development, and biomedical research. Unfortunately, chromosomes often overlap and it is necessary to identify and distinguish between the overlapping chromosomes. A segmentation solution that is fast and automated will enable scaling of co…
The paper advocates for interpretable, accountable, reproducible machine learning in medicine.
Stein-Encoder isolates genetic signals in multi-modal biomedical data.
Personalized medicine has become an important part of medicine, for instance predicting individual drug responses based on genomic information. However, many current statistical methods are not tailored to this task, because they overlook the individual heterogeneity of patients. In this paper, we look at personalized …
Bandit algorithms optimize treatment decisions for precision medicine.
Automated medical prognosis has gained interest as artificial intelligence evolves and the potential for computer-aided medicine becomes evident. Nevertheless, it is challenging to design an effective system that, given a patient's medical history, is able to predict probable future conditions. Previous works, mostly c…
This paper reviews random forest methods for analyzing longitudinal data in precision medicine.
Bayesian network structures are usually built using only the data and starting from an empty network or from a naive Bayes structure. Very often, in some domains, like medicine, a prior structure knowledge is already known. This structure can be automatically or manually refined in search for better performance models.…
Obesity is an important concern in public health, and Body Mass Index is one of the useful (and proliferant) measures. We use Convolutional Neural Networks to determine Body Mass Index from photographs in a study with 161 participants. Low data, a common problem in medicine, is addressed by reducing the information in …
This paper considers the use of Machine Learning (ML) in medicine by focusing on the main problem that this computational approach has been aimed at solving or at least minimizing: uncertainty. To this aim, we point out how uncertainty is so ingrained in medicine that it biases also the representation of clinical pheno…
Time Series Classification (TSC) problems are encountered in many real life data mining tasks ranging from medicine and security to human activity recognition and food safety. With the recent success of deep neural networks in various domains such as computer vision and natural language processing, researchers started …
Generative models create personalized patient health simulations.
The quality of machine translation is rapidly evolving. Today one can find several machine translation systems on the web that provide reasonable translations, although the systems are not perfect. In some specific domains, the quality may decrease. A recently proposed approach to this domain is neural machine translat…
3D dataset for intracranial aneurysms aids deep learning applications.
Personalized predictive medicine necessitates the modeling of patient illness and care processes, which inherently have long-term temporal dependencies. Healthcare observations, recorded in electronic medical records, are episodic and irregular in time. We introduce DeepCare, an end-to-end deep dynamic neural network t…
There is tremendous interest in precision medicine as a means to improve patient outcomes by tailoring treatment to individual characteristics. An individualized treatment rule formalizes precision medicine as a map from patient information to a recommended treatment. A treatment rule is defined to be optimal if it max…
Artificial Neural Networks (ANNs) have received increasing attention in recent years with applications that span a wide range of disciplines including vital domains such as medicine, network security and autonomous transportation. However, neural network architectures are becoming increasingly complex and with an incre…
Expands statistical background for knee osteoarthritis treatment models.
AI-enabled precision medicine promises a transformational improvement in healthcare outcomes by enabling data-driven personalized diagnosis, prognosis, and treatment. However, the well-known "curse of dimensionality" and the clustered structure of biomedical data together interact to present a joint challenge in the hi…
Develops a Causal Transformer for estimating counterfactual outcomes from longitudinal data.
Traditional medicine typically applies one-size-fits-all treatment for the entire patient population whereas precision medicine develops tailored treatment schemes for different patient subgroups. The fact that some factors may be more significant for a specific patient subgroup motivates clinicians and medical researc…
Private RL algorithm with privacy guarantees for personalized medicine decisions.
Recent exploration of optimal individualized decision rules (IDRs) for patients in precision medicine has attracted a lot of attention due to the heterogeneous responses of patients to different treatments. In the existing literature of precision medicine, an optimal IDR is defined as a decision function mapping from t…
Proposes DSW for unbiased ITE estimation with dynamic confounders.
Develops methods to learn optimal treatment regimes using causal tree methods.
Proposes a federated transfer learning method to improve precision medicine models for underrepresented populations.
Survey on understanding neural networks for medical applications.
GraphMoE generates random graphs using neural networks and graphlets.
HAD-Net forecasts glucose levels with insights into insulin and carbs diffusion.
Precision medicine has received attention both in and outside the clinic. We focus on the latter, by exploiting the relationship between individuals' social interactions and their mental health to develop a predictive model of one's likelihood to be depressed or anxious from rich dynamic social network data. To our kno…
AI enhances personalized drug development and decision-making in pharma.
Identifying measurable genetic indicators (or biomarkers) of a specific condition of a biological system is a key element of precision medicine. Indeed it allows to tailor diagnostic, prognostic and treatment choice to individual characteristics of a patient. In machine learning terms, biomarker discovery can be framed…
Framework integrates mental disorder measurements for personalized treatment.
CAPITAL algorithm identifies optimal patient subgroups for better treatment.
Bayesian model clusters diverse 'omics data for disease subtyping.
PDX studies help personalize cancer treatment.
This paper interprets neural network ECG models by breaking them into understandable components.
Falls prevention, especially in older people, becomes an increasingly important topic in the times of aging societies. In this work, we present Gated Recurrent Unit-based neural networks models designed for predicting falls (syncope). The cardiovascular systems signals used in the study come from Gravitational Physiolo…
Study uses LLMs to create personalized treatment plans for rare gynecological tumors.
Causal ML methods failed to validate their personalized treatment effects in two large trials.
In this paper, we propose a new deep feature selection method based on deep architecture. Our method uses stacked auto-encoders for feature representation in higher-level abstraction. We developed and applied a novel feature learning approach to a specific precision medicine problem, which focuses on assessing and prio…
Paper proposes federated offline RL for personalized medicine.
Scientific investigations that incorporate next generation sequencing involve analyses of high-dimensional data where the need to organize, collate and interpret the outcomes are pressingly important. Currently, data can be collected at the microbiome level leading to the possibility of personalized medicine whereby tr…
Networks of coupled dynamical systems provide a powerful way to model systems with enormously complex dynamics, such as the human brain. Control of synchronization in such networked systems has far reaching applications in many domains, including engineering and medicine. In this paper, we formulate the synchronization…
Graph Neural Network (GNN) is a popular architecture for the analysis of chemical molecules, and it has numerous applications in material and medicinal science. Current lines of GNNs developed for molecular analysis, however, do not fit well on the training set, and their performance does not scale well with the comple…
Deep learning model creates patient representations for scalable EHR-based stratification.
FUALA improves Federated Learning for EHR data, enhancing model uncertainty.