This paper proposes and implements an intuitive and pervasive solution for neonatal EEG monitoring assisted by sonification and deep learning AI that provides information about neonatal brain health to all neonatal healthcare professionals, particularly those without EEG interpretation expertise. The system aims to inc…
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48 results for “neonatal ICU”
Visual analytics system for comparing medical records using sequence embeddings.
problem Challenges in analyzing medical records due to high dimensionality, irregularity, and sparsity.
method Event and sequence embeddings using autoencoder and self-attention mechanism, with sequence alignment for comparison.
result Demonstrated effectiveness with real-world neonatal ICU dataset.
This study presents a novel end-to-end architecture that learns hierarchical representations from raw EEG data using fully convolutional deep neural networks for the task of neonatal seizure detection. The deep neural network acts as both feature extractor and classifier, allowing for end-to-end optimization of the sei…
Deep learning detects sleep state fluctuations in neonates from single EEG channel.
problem Monitoring sleep state fluctuations in neonatal intensive care units.
method Deep learning-based algorithm trained on 53 EEG recordings, validated on 30 polysomnography recordings.
result High accuracy (90%) in detecting quiet sleep states from single EEG channel, generalizing well to external dataset.
This study presents a novel, deep, fully convolutional architecture which is optimized for the task of EEG-based neonatal seizure detection. Architectures of different depths were designed and tested; varying network depth impacts convolutional receptive fields and the corresponding learned feature complexity. Two deep…
Synthetic learning improves neonatal brain MRI segmentation robustness.
problem Challenges in neonatal brain MRI segmentation due to image contrast and anatomical variations.
method Synthetic learning model trained on few T2-weighted volumes, then enhanced with motion artifacts and over-segmentation.
result Synthetic learning robust to image contrast and improves segmentation of both T1- and T2-weighted images.
Estimates future ICU demand using age-structured data and logistic modeling.
problem Projecting future ICU demand from low-quality data.
method Age-structured sampling, logistic fit, subnotification factor correction.
result Corrected logistic curve projects future ICU demand.
Early recognition of risky trajectories during an Intensive Care Unit (ICU) stay is one of the key steps towards improving patient survival. Learning trajectories from physiological signals continuously measured during an ICU stay requires learning time-series features that are robust and discriminative across diverse …
Computable Phenotypes to Characterize Changing Patient Brain Dysfunction in the Intensive Care Unitq-bio.QM
Study developed phenotypes for ICU patients' brain dysfunction states.
problem Underdiagnosis of acute brain dysfunction in ICU patients.
method Created algorithms to quantify and cluster brain dysfunction states.
result Developed three phenotypes of ICU patients' brain dysfunction states.
Monitoring patients in ICU is a challenging and high-cost task. Hence, predicting the condition of patients during their ICU stay can help provide better acute care and plan the hospital's resources. There has been continuous progress in machine learning research for ICU management, and most of this work has focused on…
Study develops electronic phenotypes of ICU patient acuity.
problem Limited time for patient acuity assessments and imprecise clinical trajectory prediction.
method Developed electronic phenotypes using automated variable retrieval in electronic health records.
result Identified three phenotypes: persistently stable, persistently unstable, and transitioning from unstable to stable.
Good predictors of ICU Mortality have the potential to identify high-risk patients earlier, improve ICU resource allocation, or create more accurate population-level risk models. Machine learning practitioners typically make choices about how to represent features in a particular model, but these choices are seldom eva…
Robust policies improve ICU transfer outcomes by predicting patient deterioration.
problem Higher mortality rates for unplanned ICU transfers.
method Markov Decision Process model to predict patient severity and optimize transfer policies.
result Robust policies are more aggressive in transferring patients than nominal policies, improving overall patient care.
Study describes severe dengue ICU patients in Brazil, 2012-2024.
problem Characterize severe dengue ICU patients and identify risk factors.
method Prospective study, descriptive statistics, logistic regression, machine learning.
result Advanced age, comorbidities, leukocytes, and platelets are significant risk factors for complications.
Late fusion of clinical notes and physiological data improves ICU mortality prediction.
problem Improving ICU mortality prediction using multimodal data.
method Late fusion of clinical notes and physiological time series data with a deep learning architecture.
result Late fusion approach provides statistically significant improvement in mortality prediction performance.
Aiming for Relevancecs.LG
Novel metrics improve machine learning models for ICU patient care.
problem Predicting vital sign trajectories for early detection of adverse events.
method Developed novel performance metrics aligned with clinical contexts, validated on simulated and real datasets, and optimized neural networks using these metrics.
result Neural networks trained with these metrics excel in predicting clinically significant events.
Modeling physiological time-series in ICU is of high clinical importance. However, data collected within ICU are irregular in time and often contain missing measurements. Since absence of a measure would signify its lack of importance, the missingness is indeed informative and might reflect the decision making by the c…
Study proposes managing COVID-19 without economy shutdowns.
problem Avoiding lockdowns while maintaining healthcare system capacity.
method Detailed heterogeneous epidemiological model, calibrated to data.
result Countries can avoid lockdowns if ICU beds per million > 100.
We considered observational data available from the MIMIC-III open-access ICU database and collected within a study period between year 2002 up to 2011. If a patient had multiple admissions to the ICU during the 30 days before death, only the first stay was analyzed, leading to a final set of 6,436 unique ICU admission…
Early Prediction of 30-day ICU Re-admissions Using Natural Language Processing and Machine Learningcs.LG
ICU readmission is associated with longer hospitalization, mortality and adverse outcomes. An early recognition of ICU re-admission can help prevent patients from worse situation and lower treatment cost. As the abundance of Electronics Health Records (EHR), it is popular to design clinical decision tools with machine …
Paper uses RL to optimize ICU load during COVID-19.
problem Optimizing ICU load during a pandemic.
method Combines epidemic model, Bayesian inference, and RL for adaptive intervention levels.
result RL policies reduce ICU burden compared to historical interventions.
Current machine learning models aiming to predict sepsis from Electronic Health Records (EHR) do not account for the heterogeneity of the condition, despite its emerging importance in prognosis and treatment. This work demonstrates the added value of stratifying the types of organ dysfunction observed in patients who d…
WRSE predicts dynamic survival distributions in ICU patients.
problem Dynamic assessment of ICU patient mortality risk.
method Non-parametric weighted-resolution ensemble model combining binary classifiers.
result Competitive results with state-of-the-art models, reducing training time.
Identification of physiological shock in intensive care units via Bayesian regime switching modelsstat.AP
Bayesian model detects internal bleeding in ICU patients.
problem Late detection of internal bleeding in ICU patients.
method Bayesian regime switching model analyzing vitals and labs.
result Probabilistic assessment of patient's physiological state.
The paper tackles ICU discharge strategies by evaluating optimal stopping scenarios.
problem Optimal stopping in ICU discharge with complex causal inference challenges.
method Generalized g-formula implementation and application to MIMIC-IV dataset.
result Improved ICU discharge strategies demonstrated with the g-formula approach.
Deep learning predicts ICU mortality with enhanced interpretability.
problem Improving mortality prediction accuracy and clinician trust in AI.
method Trained a deep learning model on MIMIC-III to interpret nursing notes.
result Model reaches ROC of 0.8629, outperforming SAPS-II.
Objective: Predict patient-specific vitals deemed medically acceptable for discharge from a pediatric intensive care unit (ICU). Design: The means of each patient's hr, sbp and dbp measurements between their medical and physical discharge from the ICU were computed as a proxy for their physiologically acceptable state …
New method identifies key channels for extreme brain events.
problem Identifying channels responsible for extreme brain events like seizures.
method Extends canonical correlation to tail dependence, developing TPDM for clustering.
result Tail connectivity provides additional discriminatory power for seizure risk.
System predicts respiratory failure up to 8 hours early.
problem Early detection of respiratory failure in ICU patients.
method Machine learning on ICU patient monitoring data.
result System outperforms traditional clinical decision-making.
Bedside monitors in Intensive Care Units (ICUs) frequently sound incorrectly, slowing response times and desensitising nurses to alarms (Chambrin, 2001), causing true alarms to be missed (Hug et al., 2011). We compare sliding window predictors with recurrent predictors to classify patient state-of-health from ICU multi…
Novel IRL method identifies suboptimal medical decisions in ICU data.
problem Identifying suboptimal medical decisions in clinical settings.
method Incorporates Inverse Reinforcement Learning with a pruning step to identify and remove suboptimal actions.
result Pruning step effectively identifies clinical priorities and values from suboptimal data.
Predicting Length of Stay in the Intensive Care Unit with Temporal Pointwise Convolutional Networkscs.LG
New model predicts ICU patients' stay duration efficiently.
problem Efficient ICU bed allocation under resource constraints.
method Temporal Pointwise Convolution (TPC) model combining temporal and pointwise convolutions.
result Significant performance improvements over LSTM and Transformer models.
ICU mortality scoring systems attempt to predict patient mortality using predictive models with various clinical predictors. Examples of such systems are APACHE, SAPS and MPM. However, most such scoring systems do not actively look for and include interaction terms, despite physicians intuitively taking such interactio…
Proposes inference for DNNs in GNRMs, addressing non-independence issues.
problem Inference for DNN-estimated means in GNRMs under non-independence.
method Develops a DNN estimator and ESM for variance estimation and confidence intervals.
result Demonstrates feasibility of inference under GNRMs with ESM.
Kernel-Based Learning of Chest X-ray Images for Predicting ICU Escalation among COVID-19 Patientscs.LG
Kernel-based learning predicts ICU escalation from COVID-19 chest X-rays.
problem Predicting ICU escalation from chest X-rays using complex data patterns.
method Generalized Linear Models with Integrated Multiple Additive Regression with Kernels (GLIMARK).
result GLIMARK effectively predicts ICU escalation from chest X-rays.
After admission to emergency department (ED), patients with critical illnesses are transferred to intensive care unit (ICU) due to unexpected clinical deterioration occurrence. Identifying such unplanned ICU transfers is urgently needed for medical physicians to achieve two-fold goals: improving critical care quality a…
Develops framework for estimating and improving DTRs with time-varying IV in the presence of unmeasured confounding.
problem Estimating DTRs from observational data with unmeasured confounding.
method Time-varying instrumental variable (IV) framework for estimating and improving DTRs.
result IV-optimal and IV-improved DTRs perform better than DTRs assuming no unmeasured confounding.
Traditional methods for assessing illness severity and predicting in-hospital mortality among critically ill patients require time-consuming, error-prone calculations using static variable thresholds. These methods do not capitalize on the emerging availability of streaming electronic health record data or capture time…
Electronic Medical Records (EMR) are a rich source of patient information, including measurements reflecting physiologic signs and administered therapies. Identifying which variables are useful in predicting clinical outcomes can be challenging. Advanced algorithms such as deep neural networks were designed to process …
Temporal Pointwise Convolutional Networks for Length of Stay Prediction in the Intensive Care Unitcs.LG
New model predicts ICU patient stays more accurately.
problem Efficient ICU bed allocation under resource constraints.
method Temporal Pointwise Convolutional Networks (TPC) combining temporal and pointwise convolutions.
result Significant performance improvements over LSTM and Transformer models.
Determining whether hypotensive patients in intensive care units (ICUs) should receive fluid bolus therapy (FBT) has been an extremely challenging task for intensive care physicians as the corresponding increase in blood pressure has been hard to predict. Our study utilized regression models and attention-based recurre…
Study automates detection of visitation disruptions in ICU patients.
problem Difficulty in detecting frequent visitation disruptions in ICU patients.
method Used DensePose R-CNN model to count people in video frames, analyzed disruptions and patient outcomes.
result Automated method detects visitation disruptions, impacts on pain and length of stay examined.
Bayesian Modelling in Practice: Using Uncertainty to Improve Trustworthiness in Medical Applicationscs.LG
The Intensive Care Unit (ICU) is a hospital department where machine learning has the potential to provide valuable assistance in clinical decision making. Classical machine learning models usually only provide point-estimates and no uncertainty of predictions. In practice, uncertain predictions should be presented to …
Every year, 3 million newborns die within the first month of life. Birth asphyxia and other breathing-related conditions are a leading cause of mortality during the neonatal phase. Current diagnostic methods are too sophisticated in terms of equipment, required expertise, and general logistics. Consequently, early dete…
ICU mortality risk prediction is a tough yet important task. On one hand, due to the complex temporal data collected, it is difficult to identify the effective features and interpret them easily; on the other hand, good prediction can help clinicians take timely actions to prevent the mortality. These correspond to the…
New design detects confounders from treatment intent in ICU data.
problem Unobserved confounding in observational ICU data.
method Querying human experts to identify unobserved confounders.
result Demonstrates feasibility of detecting confounders from EHRs.
Over the past decades, both critical care and cancer care have improved substantially. Due to increased cancer-specific survival, we hypothesized that both the number of cancer patients admitted to the ICU and overall survival have increased since the millennium change. MIMIC-III, a freely accessible critical care data…
Study improves predictive models for ICU data across hospitals.
problem Degradation of predictive model performance in new hospitals.
method Anchor regression and anchor boosting for domain generalization.
result Anchor regularization enhances out-of-distribution performance.