Paper proposes DTW-SOM for visual exploration of time-series motifs.
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The discovery of time series motifs has emerged as one of the most useful primitives in time series data mining. Researchers have shown its utility for exploratory data mining, summarization, visualization, segmentation, classification, clustering, and rule discovery. Although there has been more than a decade of exten…
New method discovers time series motifs under DTW, significantly reducing computations.
Time Series Motif Discovery (TSMD) is defined as searching for patterns that are previously unknown and appear with a given frequency in time series. Another problem strongly related with TSMD is Word Segmentation. This problem has received much attention from the community that studies early language acquisition in ba…
TF-MoDISco (Transcription Factor Motif Discovery from Importance Scores) is an algorithm for identifying motifs from basepair-level importance scores computed on genomic sequence data. This technical note focuses on version v0.5.6.5. The implementation is available at https://github.com/kundajelab/tfmodisco/tree/v0.5.6…
Paper discovers manoeuvres from vehicle telematics data.
MotiFiesta learns network motifs efficiently.
Time series motifs play an important role in the time series analysis. The motif-based time series clustering is used for the discovery of higher-order patterns or structures in time series data. Inspired by the convolutional neural network (CNN) classifier based on the image representations of time series, motif diffe…
Complex systems, such as airplanes, cars, or financial markets, produce multivariate time series data consisting of a large number of system measurements over a period of time. Such data can be interpreted as a sequence of states, where each state represents a prototype of system behavior. An important problem in this …
New model generates larger molecules more effectively.
HiGraphDTI learns drug and target representations from molecular graphs to predict DTIs.
The last decade has seen a flurry of research on all-pairs-similarity-search (or, self-join) for text, DNA, and a handful of other datatypes, and these systems have been applied to many diverse data mining problems. Surprisingly, however, little progress has been made on addressing this problem for time series subseque…
Motivation: Prediction of the interaction affinity between proteins and compounds is a major challenge in the drug discovery process. WideDTA is a deep-learning based prediction model that employs chemical and biological textual sequence information to predict binding affinity. Results: WideDTA uses four text-based inf…
Method finds motifs in knowledge graphs, revealing their structure.
Improved scaffold generation for protein motifs using SE(3) flow matching.
Networks are a fundamental tool for modeling complex systems in a variety of domains including social and communication networks as well as biology and neuroscience. Small subgraph patterns in networks, called network motifs, are crucial to understanding the structure and function of these systems. However, the role of…
Researchers create exact minimal surfaces with helical motifs in biological structures.
Behaviors of several laboratory animals can be modeled as sequences of stereotyped behaviors, or behavioral motifs. However, identifying such motifs is a challenging problem. Behaviors have a multi-scale structure: the animal can be simultaneously performing a small-scale motif and a large-scale one (e.g. \textit{chewi…
odeN efficiently approximates multiple temporal motifs in large networks.
Computational approaches to transcription factor binding site identification have been actively researched for the past decade. Negative examples have long been utilized in de novo motif discovery and have been shown useful in transcription factor binding site search as well. However, understanding of the roles of nega…
Synthetic Petri Dish predicts neural architecture performance faster.
FoundCause: Causal Discovery with Latent Confounders from Observational Data
A motif-based framework identifies local spillover structures in financial markets.
Generative graph models create instances of graphs that mimic the properties of real-world networks. Generative models are successful at retaining pairwise associations in the underlying networks but often fail to capture higher-order connectivity patterns known as network motifs. Different types of graphs contain diff…
New method learns diverse protein scaffolds for motif design.
PGEL learns embeddings to diversify protein motifs while maintaining biological function.
Model improves robustness of neural network sequences without transition failures.
New method clusters weighted directed networks using motifs.
New method uses diffusion models to generate proteins with specific motifs.
Proposes a motif-preserving Graph Neural Network for financial default prediction.
In this paper, we introduce the notion of motif closure and describe higher-order ranking and link prediction methods based on the notion of closing higher-order network motifs. The methods are fast and efficient for real-time ranking and link prediction-based applications such as web search, online advertising, and re…
Generalized belief propagation converges to optimal solutions on graphs with motifs.
Paper constructs motifs from planar tilings for DP weaves and polycatenanes.
BaGGLS models biological interactions using Bayesian shrinkage for interpretability.
The paper models musical motif transformations in Beethoven's works.
Motivated by the concept of network motifs we construct certain clustering methods (functors) which are parametrized by a given collection of motifs (or representers).
When analyzing the genome, researchers have discovered that proteins bind to DNA based on certain patterns of the DNA sequence known as "motifs". However, it is difficult to manually construct motifs due to their complexity. Recently, externally learned memory models have proven to be effective methods for reasoning ov…
When each data point is a large graph, graph statistics such as densities of certain subgraphs (motifs) can be used as feature vectors for machine learning. While intuitive, motif counts are expensive to compute and difficult to work with theoretically. Via graphon theory, we give an explicit quantitative bound for the…
New approach learns latent motifs in networks for mesoscale structure analysis.
When learning a hidden Markov model (HMM), sequen- tial observations can often be complemented by real-valued summary response variables generated from the path of hid- den states. Such settings arise in numerous domains, includ- ing many applications in biology, like motif discovery and genome annotation. In this pape…
KCoreMotif clusters large networks efficiently by exploiting k-core decomposition and motifs.
We study soft persistence (existence in subsequent temporal layers of motifs from the initial layer) of motif structures in Triangulated Maximally Filtered Graphs (TMFG) generated from time-varying Kendall correlation matrices computed from stock prices log-returns over rolling windows with exponential smoothing. We ob…
This paper classifies periodic weaves and their universal cover, extending Tait's conjectures.
Paper defines and analyzes mathematical equivalence of periodic tangles.
Bayesian network models are finding success in characterizing enzyme-catalyzed reactions, slow conformational changes, predicting enzyme inhibition, and genomics. In this work, we apply them to statistical modeling of peptides by simultaneously identifying amino acid sequence motifs and using a motif-based model to cla…
In this paper, we consider the problem of fast and efficient indexing techniques for sequences evolving in non-Euclidean spaces. This problem has several applications in the areas of human activity analysis, where there is a need to perform fast search, and recognition in very high dimensional spaces. The problem is ma…
Understanding urban dynamics, i.e., how the types and intensity of urban residents' activities in the city change along with time, is of urgent demand for building an efficient and livable city. Nonetheless, this is challenging due to the expanding urban population and the complicated spatial distribution of residents.…
We study trade-based manipulation of stock prices from the perspective of complex trading networks constructed by using detailed information of trades. A stock trading network consists of nodes and directed links, where every trader is a node and a link is formed from one trader to the other if the former sells shares …