Study causal inference under specific sampling methods with monotonicity assumptions.
problem Causal inference under biased sampling methods.
method Binary-outcome and binary-treatment case study with monotonicity assumptions.
result Monotonicity assumptions yield comparable results to random sampling.
Study shows auditing fairness of personalized interventions is impossible due to unknown ground truths.
problem Auditing fairness of personalized interventions in social services, education, and healthcare.
method Point-identification of quantities under monotone treatment response assumption, providing sensitivity analysis for violations.
result Proves impossibility of auditing fairness using standard metrics and provides methods for auditing using partially-identified ROC and xROC curves.
New method estimates treatment-response curves with covariate and timing measurement errors.
problem Estimating treatment impact on continuous temporal response with covariate measurement errors.
method Combines parametric response functions and sparse Gaussian process for baseline trend, considering both treatment covariates and timing errors.
result Significant improvements in estimation accuracy and prediction for diet impact on blood glucose measurements.
Bayesian model for cancer drug studies maps dose-response curves.
problem Mapping dose-response curves in cancer drug studies.
method Bayesian Tensor Filtering (BTF) with low-dimensional embeddings and structured shrinkage priors.
result BTF outperforms state-of-the-art methods in cancer drug studies.
The paper addresses estimating long-term treatment effects with monotone missing data.
problem Estimating long-term treatment effects with missing data, especially monotone missing.
method The paper introduces the sequential missingness assumption for identification and proposes three novel estimation methods: inverse probability weighting, sequential regression imputation, and SeqMSM. It also introduces a balancing-enhanced approach, BalanceNet, to improve estimation accuracy.
result The proposed methods, including BalanceNet, effectively estimate long-term treatment effects with monotone missing data.
We study the problem of estimating the continuous response over time to interventions using observational time series---a retrospective dataset where the policy by which the data are generated is unknown to the learner. We are motivated by applications where response varies by individuals and therefore, estimating resp…
Proposes a method for generating prediction intervals in dose-response models using conformal prediction.
problem Uncertainty quantification in continuous treatments for personalized healthcare decisions.
method Causal dose-response problem framed as covariate shift, using weighted conformal prediction with propensity estimation and kernel functions.
result Demonstrates the significance of covariate shift assumptions for robust prediction intervals.
Designs algorithms to assist humans without affecting their decisions.
problem Algorithms often fail to improve human decisions.
method Formalizes algorithm design using potential outcomes framework and monotonicity assumption.
result Derives minimax optimal recommendation algorithms for limited data.
Unified framework for response-adaptive targeting in multi-treatment experiments
problem Improving ethical and statistical efficiency in multi-treatment clinical trials
method Response-adaptive targeting strategies
result Unified framework for α-Rebalancing Targeting Strategies (αRTS) Bayesian model ranks treatments in multi-response experiments.
problem Identifying the best treatment among competing ideal properties.
method Bayesian approach with Markov Chain Monte Carlo algorithm.
result Reliable inference of treatment ranks in practice.
Estimates personalized treatment response curves using covariates.
problem Flexible estimation of personalized treatment response curves.
method Sieve based nonparametric estimator of smoothed regimen-response curve function.
result Asymptotic linearity and undersmoothing criteria for efficient estimation.
Treatment effects can be estimated from observational data as the difference in potential outcomes. In this paper, we address the challenge of estimating the potential outcome when treatment-dose levels can vary continuously over time. Further, the outcome variable may not be measured at a regular frequency. Our propos…
In the context of individual-level causal inference, we study the problem of predicting whether someone will respond or not to a treatment based on their features and past examples of features, treatment indicator (e.g., drug/no drug), and a binary outcome (e.g., recovery from disease). As a classification task, the pr…
New method estimates treatment effects over time with unobserved confounders.
problem Estimating treatment effects from observational data with unobserved confounders.
method Sequential Deconfounder using Gaussian process latent variable model.
result Unbiased estimates of individualized treatment responses over time.
Estimating what would be an individual's potential response to varying levels of exposure to a treatment is of high practical relevance for several important fields, such as healthcare, economics and public policy. However, existing methods for learning to estimate counterfactual outcomes from observational data are ei…
Proposes DeepSDRF for continuous treatment recommendation from clinical survival data.
problem Continuous treatment recommendation in medical settings with survival data.
method Deep Survival Dose Response Function (DeepSDRF) for learning conditional average dose response (CADR) function.
result Similar performance of recommender algorithms based on random search and reinforcement learning.
Method estimates treatment effects with continuous values, correcting for confounding.
problem Estimating treatment effects with continuous values, dealing with confounding.
method Two-stage kernel ridge regression: first stage learns response, second stage corrects for distribution shift.
result Optimal learning bounds achieved without estimating treatment density, adapts to unknown overlap and kernel spectral decay.
ContiVAE estimates individual dose-response curves from unobserved confounders using observational data.
problem Estimating causal effects of continuous treatments considering unobserved confounders.
method Variational auto-encoder with a Tilted Gaussian prior distribution modeling hidden confounders as latent variables.
result ContiVAE outperforms existing methods by up to 62% in predicting individual dose-response curves.
Paper develops methods to estimate derivative of dose-response curve for continuous treatments.
problem Estimating the derivative of the dose-response curve for continuous treatments.
method Doubly robust (DR) inference method using kernel smoothing, bias-corrected IPW and DR estimators.
result Proposes novel bias-corrected IPW and DR estimators for continuous treatments.
Kernel methods identify treatment effects with unobserved confounding using negative controls.
problem Learning causal relationships with unmeasured confounding.
method Kernel ridge regression algorithms for nonparametric treatment effects.
result Uniform consistency and finite sample rates of convergence proved.
CausalLongPFN predicts counterfactual outcomes from time-series data.
problem Predicting future outcomes under varying treatments in time-series data with confounding and heterogeneity.
method Prior-fitted network pretrained on synthetic episodes of temporal structural causal models.
result CausalLongPFN outperforms domain-trained models on factual and counterfactual prediction tasks.
Proposes a method to estimate causal effects of continuous treatments using instrumental variables.
problem Estimating causal effects of continuous treatments in the presence of unmeasured confounders.
method Introduces a novel framework using instrumental variables and a uniform regular weighting function to identify and estimate average dose-response functions.
result Establishes the asymptotic properties of the proposed methods for estimating average dose-response functions.
Paper introduces new estimator for continuous treatment effects.
problem Estimating the average dose-response function of continuous treatments.
method Utilizes ADML and DML tools, with a novel debiasing method.
result Proves asymptotic normality and shows good performance in simulations.
Method bounds continuous-valued treatment effects when confounding variables are hidden.
problem Inferring causal effects of continuous treatments when hidden confounders are present.
method Novel methodology to bound average and conditional average continuous-valued treatment effects.
result Method gives tighter coverage of true dose-response curve than existing methods.
Optimum in Convex Hulls (OCH) generalizes clinical trial results to broader populations.
problem Clinical trials exclude confounding but limit recruitment; observational data are more inclusive but suffer from confounding.
method OCH uses convex hulls of conditional expectations or densities to approximate the true treatment effect from both observational and trial data.
result OCH estimates the treatment effect with state-of-the-art accuracy in terms of both expectations and densities.
Scientists develop a model to identify treatment responders from non-responders.
problem Analyzing samples that respond to treatment in studies.
method Causal two-groups (C2G) model, empirical Bayes procedures.
result The C2G model controls false discovery rate and has near-optimal power.
New method tackles adversarial sign-corrupted isotonic regression, estimating monotonic signals under heavy dependence.
problem Estimating monotonic signals when responses are sign-corrupted and adversarially designed to violate monotonicity.
method Developed ASCIFIT, a three-step estimation procedure using PAVA with pre- and post-processing corrections.
result Theoretical guarantees of sharp high probability upper bounds and minimax lower bounds for ASCIFIT.
Deep learning predicts response to HER2-targeted breast cancer therapy.
problem Predicting response to HER2-targeted neoadjuvant chemotherapy.
method Developed and validated a deep learning approach using pre-treatment dynamic breast MRI.
result Deep learning model achieved strong performance in predicting pathological complete response.
New method estimates effects of multiple nutrients on blood glucose.
problem Estimating physiological response to multiple nutrient treatments.
method Convolution-based multi-output Gaussian process model.
result Improved prediction accuracy and better interpretation of individual nutrient effects.
IntelligentPooling improves treatment decisions in mHealth.
problem Optimizing treatment decisions in mobile health with limited data and non-stationary responses.
method Generalized Thompson-Sampling bandit algorithms to IntelligentPooling, addressing differential response, limited data, and non-stationary responses.
result IntelligentPooling achieves 26% lower regret compared to state-of-the-art methods.
Estimates impulse response functions using machine learning in time series data.
problem Estimating causal effects of discrete treatments over time with flexible models.
method Double/debiased machine learning for nonparametric time series data.
result Consistent and asymptotically normal estimator for impulse response functions.
Estimates individualized treatment effects using shared RBF-net neurons.
problem Identifying differential treatment effects based on covariates.
method Non-parametric radial basis function (RBF)-nets with shared hidden neurons in a Bayesian framework.
result Demonstrated through simulations and real data, the method identifies interesting treatment effects.
Overview of high-dimensional dynamical systems and their applications to machine learning.
problem Characterizing behavior of high-dimensional dynamical systems driven by random matrices.
method Cavity method arguments, path integrals, dynamical mean field theory (DMFT), and random matrix resolvents.
result Connections between random matrix resolvents and DMFT response, and non-monotonic loss curves in training.
Paper models treatment effects by clustering patients with distinct survival characteristics.
problem Estimating treatment efficacy in clinical settings with censored outcomes.
method Latent variable approach to model heterogeneous treatment effects.
result The latent structure can mediate base survival rates and reveal actionable phenotypes.
Study optimal and equitable encouragement policies for treatment adherence.
problem Optimal treatment adherence policies in the presence of human non-adherence.
method Covariate-conditional no-direct-effect model of encouragement; tractable policy characterizations under constraints.
result Induced treatment take-up is the fairness target, not recommendation rates.
Proposes estimators for complex dose-response curves using kernel methods.
problem Estimating complex dose-response curves with continuous treatments, mediators, and covariates.
method Kernel ridge regression with sequential kernel embedding technique.
result Simple estimators for mediated and time-varying dose response curves with nonasymptotic uniform rates.
REP predicts drug response at every stage of treatment using time-course gene expression data.
problem Lack of dynamic drug response prediction from time-course gene expression data.
method REP framework that predicts drug response values at every stage of a long-term treatment using recursive structure and tensor completion.
result REP can estimate drug response at any stage of a given treatment from initial gene expression levels.
New method removes hidden confounders for unbiased treatment effect estimation.
problem Bias in treatment effect estimation due to unobserved confounders.
method Proposes a new debiased estimation approach via SVD to handle heterogeneous confounding.
result Established rate of convergence for the estimator under different noise conditions.
The paper uses deep neural networks to estimate and infer ATE without needing to know the dimension of the data.
problem Estimating and inferring the average treatment effect (ATE) in complex data settings.
method The paper uses deep neural networks to estimate the mean regression function and then calculates the ATE. It establishes consistency and asymptotic normality of the estimators.
result The deep neural network estimates of ATE are consistent and asymptotically normal, providing dimension-free rates.
The paper bounds and identifies joint probabilities in causal inference with monotonicity assumptions.
problem Bounding and identifying joint probabilities of potential outcomes and observed variables under monotonicity assumptions.
method Proposes new families of monotonicity assumptions, formulates bounding problem as linear programming, introduces new monotonicity assumption for identification.
result Validated methods through numerical experiments and applied to real-world datasets.
A new algorithm learns optimal personalized treatment plans online with low regret.
problem Learning optimal dynamic treatment regimes in an online setting.
method Developed a novel algorithm balancing exploration and exploitation for rate-optimal regret.
result Guaranteed rate-optimal regret for linear transition and reward models.
A treatment regime is a function that maps individual patient information to a recommended treatment, hence explicitly incorporating the heterogeneity in need for treatment across individuals. Patient responses are dichotomous and can be predicted through an unknown relationship that depends on the patient information …
Proposes a deep learning framework for estimating counterfactual outcomes.
problem Challenges in estimating individual outcomes under different treatments.
method Deep variational Bayesian framework integrating factual and similar subjects' outcomes.
result Rigorously integrates individual features and similar subjects' responses for counterfactual outcomes.
Study shows how adjusting for a binary proxy can bound causal effects.
problem Bounding causal effects with a binary confounder and proxy.
method Monotonicity assumption applied to a binary confounder and observed proxy.
result Adjusting for a proxy produces a measure of the effect between unadjusted and true measures.
Demand response is designed to motivate electricity customers to modify their loads at critical time periods. The accurate estimation of impact of demand response signals to customers' consumption is central to any successful program. In practice, learning these response is nontrivial because operators can only send a …
Estimates price sensitivity from transaction data using a novel odds ratio method.
problem Estimate price sensitivity from transaction-level data with partially observed treatment assignments.
method Recursive partitioning procedure with adversarial imputation for robust estimation.
result Validated on synthetic data and applied to three case studies, demonstrating heterogeneity in treatment effects.
Machine learning improves glioma diagnosis and prognosis.
problem Improving glioma diagnosis and prognosis using imaging biomarkers.
method Search PubMed and MEDLINE for articles applying machine learning to high-grade glioma biomarkers.
result Machine learning enables accurate classification of glioma biomarkers.
Study presents MMC model for better fitting multiple choice data.
problem Improving accuracy of latent trait estimates in IRT models.
method Fit autoencoders to MMC model, demonstrating better fit than nominal response model.
result MMC model outperforms traditional IRT models in fit.