Dual neural network improves treatment recommendations from medical history.
problem Improving treatment recommendations from patient medical history.
method Memory-augmented neural network with dual controllers.
result Dual controller write-protected memory-augmented neural network outperformed traditional methods.
Deep learning predicts vascular disease from medical history.
problem Predicting high-risk vascular diseases from medical records.
method Medical History-based Prediction using Attention Network (MeHPAN) models.
result MeHPAN models outperform standard classification models.
Paper proposes embedding medical concepts from claims data for better risk adjustment models.
problem Lack of efficient representation of medical histories in risk adjustment models.
method Semantic embeddings of medical concepts from diagnostic, procedure, and prescription codes.
result Embedding-based models outperform commercial risk adjustment models in prospective risk score prediction.
RL algorithms with medical integration improve personalized treatment recommendations.
problem Developing effective personalized treatment strategies for chronic diseases.
method Integrating medical knowledge into RL algorithms for DTR.
result Enhanced treatment recommendations with increased confidence.
CRN model estimates treatment effects over time using adversarial balancing.
problem Estimating treatment effects over time in medical settings.
method Adversarial domain balancing to remove time-varying confounders.
result CRN achieves lower error in estimating counterfactuals and treatment timing.
GAMENet uses graph memory networks to recommend safe medication combinations.
problem Lack of personalized and safe medication combination recommendations considering patient history and drug interactions.
method Integrates drug-drug interactions knowledge graph into a memory module using graph convolutional networks and models longitudinal patient records.
result GAMENet outperformed state-of-the-art methods in effectiveness and safety, reducing DDI rate by 3.60%.
MedGraph learns patient visit embeddings from EMRs, capturing both attributes and temporal sequences.
problem Limited EMR embedding methods fail to capture patient demographics, utilisation, and code descriptions.
method MedGraph constructs an attributed bipartite graph and uses a point process to model temporal sequences.
result MedGraph outperforms state-of-the-art methods in medical risk prediction tasks.
Personalized predictive medicine necessitates the modeling of patient illness and care processes, which inherently have long-term temporal dependencies. Healthcare observations, recorded in electronic medical records, are episodic and irregular in time. We introduce DeepCare, an end-to-end deep dynamic neural network t…
Study predicts colorectal polyp recurrence using medical records and statistical models.
problem Identifying patient characteristics influencing colorectal polyp recurrence.
method Natural language processing for extracting polyp characteristics, Kaplan-Meier curves, Cox proportional hazards modeling, random survival forest models.
result Polyp size, number, location, and patient smoking status significantly influence recurrence risk.
Counterfactual diagnosis improves medical accuracy and safety.
problem Existing diagnostic algorithms struggle with distinguishing correlation from causation.
method Reformulated diagnosis as a counterfactual inference task and derived new counterfactual diagnostic algorithms.
result Counterfactual diagnostic algorithms significantly improve accuracy and safety compared to standard Bayesian algorithms.
Paper develops deep learning for predicting clinical endpoints from diverse medical records.
problem Predicting clinical endpoints from heterogeneous, irregularly visiting medical records.
method Proposes a novel model with a new gate to control visiting rates of different events.
result Model effectively predicts death and abnormal lab tests with real-world clinical data.
Deep learning predicts patient trajectories in open Mimic-III dataset.
problem Predicting future medical conditions from patient history.
method Two parallel bi-directional Minimal Gated Recurrent Unit networks trained on Mimic-III dataset.
result Significant improvements in automated medical prognosis measured by Recall@k.
Paper tackles pandemic resource allocation challenges.
problem Shortages of medical resources during pandemics.
method Risk management approach, focusing on spatio-temporal competitions.
result New strategies for optimal stockpiling and allocation balancing resource competition.
RetainVis enhances RNNs for medical record analysis, making predictions more understandable.
problem Limited interpretability and user interaction in RNN models for medical records.
method Developed RetainVis, a visual analytics tool that integrates an improved RNN model (RetainEX) with interactive visualizations.
result Users can explore EMR data and understand how individual medical codes affect predictions.
Machine learning detects NASH patients from medical claims data.
problem Detecting undiagnosed NASH patients for screening and management.
method Gradient-boosted decision trees trained on administrative medical claims data.
result Model precision for NASH detection is significantly higher than NASH incidence.
Model creates summaries of patient notes to save time and reduce errors.
problem Improper summarization of patient notes leads to inefficiencies and errors.
method Developed an LSTM model to sequentially label topics in history of present illness notes.
result Achieved an F1 score of 0.876, indicating the model's effectiveness.
Unsupervised anomaly detection aids doctors in evaluating X-ray images of hands.
problem Lack of labeled medical data and ambiguous symptoms in X-ray images.
method Adopting state-of-the-art unsupervised learning methods for anomaly detection and preprocessing.
result Without preprocessing, unsupervised methods perform randomly on X-ray images of hands.
New method uses probabilistic independence to discover disease signatures from medical records.
problem Insufficiently precise diagnosis of clinical disease leading to treatment failures.
method Unsupervised machine learning using probabilistic independence to disentangle disease patterns.
result Inferred 2000 clinical disease signatures from medical records, improving cancer prediction.
This paper explores deep learning for improving X-ray CT image reconstruction from undersampled data.
problem Improving image reconstruction from undersampled X-ray CT data.
method Analysis of classical and deep learning methods for solving inverse problems.
result Deep learning methods show promise in improving image quality from undersampled data.
Early diagnosis is important for type 2 diabetes (T2D) to improve patient prognosis, prevent complications and reduce long-term treatment costs. We present a novel risk profiling approach based exclusively on health expenditure data that is available to Belgian mutual health insurers. We used expenditure data related t…
ZiMM model predicts long-term blurry relapses from non-clinical claims data.
problem Predicting long-term blurry relapses after medical acts.
method Introduces ZiMM (Zero-inflated Mixture of Multinomial distributions) and a deep-learning architecture (ZiMM Encoder-Decoder) to learn from sparse, irregular patterns in claims data.
result ZiMM ED improves predictions over various baselines, including non-deep learning and deep-learning approaches.
Deep learning predicts opioid use disorder risk in patients.
problem Identifying patients at high risk of opioid use disorder.
method Applied LSTM models to analyze electronic health records of opioid users.
result LSTM model outperformed other methods with F1 score of 0.8023 and AUCROC of 0.9369.
The paper proposes a method to explain expert decisions by modeling preferences with 'what if' outcomes.
problem Interpreting and auditing decision-making policies in institutions.
method Integrating counterfactual reasoning into batch inverse reinforcement learning.
result The method effectively recovers accurate and interpretable descriptions of expert behavior.
Differentially private dropout technique preserves privacy in neural network training.
problem Preserving privacy in large datasets used for neural network training.
method Introduces a Bayesian dropout technique that adds intrinsic noise for regularization and differential privacy.
result Demonstrates that the iterative nature of neural network training can be handled with a relaxed differential privacy concept.
Developed a new algorithm to improve dynamic treatment regimens.
problem Non-convergence of Q-learning-based Q-shared algorithm in dynamic treatment regimens.
method Penalized Q-shared algorithm to address convergence issues.
result The penalized Q-shared algorithm converges and outperforms the original in various settings.
Supervised topic models improve clinical diagnostics by interpreting cooccurence patterns in count data.
problem Standard supervised Latent Dirichlet Allocation (sLDA) struggles with documents having many more words than labels and lacks effective use of supervised labels.
method Investigates penalized optimization methods to train interpretable sLDA models using recognition networks for faster inference.
result Preliminary results show improved predictions on heldout data for predicting anti-depressant medication success based on patient history.
Privacy distillation lets patients control their data for medical models.
problem Patient self-censorship due to privacy concerns impairs personalized treatment accuracy.
method Privacy distillation using deep neural networks to retain model accuracy with partial patient data.
result Privacy distillation maintains model accuracy with only 3% loss and reduces health risks by 3.9%.
Bayesian inference over admissible histories leads to irreversible kinetics.
problem Modeling irreversible processes in systems with uncertain histories.
method A Gibbs-type measure weighted by energy-dissipation action and observation constraints, interpreted as a Bayesian posterior.
result The measure concentrates on maximum-a-posteriori (MAP) histories, recovering classical deterministic evolution.
Method learns optimal treatment sequences from observational data.
problem Optimal dynamic treatment regimes for public policies and medical interventions.
method Doubly robust classification-based approach via backward induction.
result Achieves optimal convergence rate of n^(-1/2) for welfare regret.
HS-FNO models non-Markovian PDEs by learning history and future states.
problem Non-Markovian dynamics where future states depend on past history.
method History-Space Fourier Neural Operator (HS-FNO) for delay and memory-driven PDEs.
result HS-FNO achieves lowest aggregate errors across various PDE families.
Overview of affine surface area and its history.
problem None explicitly stated; focuses on overview.
method None explicitly stated; focuses on overview.
result None explicitly stated; focuses on overview.
Survey of Baum-Connes conjecture history and methods.
problem Baum-Connes conjecture in mathematics.
method History and methods of the conjecture.
result Current status of the conjecture.
Survey on DDVV-type inequalities, their history, and recent developments.
problem None explicitly stated; focuses on surveying existing work.
method None explicitly stated; focuses on surveying existing work.
result Survey of DDVV-type inequalities and their history and recent developments.
SRMC framework reduces Monte Carlo variance by history-based sampling in high-dimensional spaces.
problem Efficient sampling in high-dimensional discrete or continuous state spaces.
method Score-Repellent Monte Carlo (SRMC) framework that summarizes history through running average of score evaluations.
result Improves estimator variance and mode coverage with constant memory usage.
Paper analyzes history-based RL methods for MDPs, introduces a theoretical framework and practical algorithm.
problem Improving RL performance in MDPs using history-based features.
method Theoretical framework for history-based RL, practical algorithm design.
result Practical RL algorithm shows effectiveness on continuous control tasks.
Neural networks improve cancer risk prediction from family history data.
problem Improving cancer risk prediction from family history data using machine learning.
method Developed and trained neural network models on large pedigrees to predict hereditary cancers.
result Neural networks can achieve nearly optimal prediction performance and outperform traditional models in misreported data.
The paper explains why estimating a history-dependent policy can reduce MSE in reinforcement learning.
problem Understanding why history-dependent policies can improve MSE in off-policy evaluation.
method The paper derives a bias-variance decomposition of MSE for various OPE estimators, showing how history-dependent policies can decrease variance and increase bias.
result History-dependent policies can decrease the variance of importance sampling estimators, leading to lower MSE.
New algorithm minimizes regret in stochastic linear bandits with perturbed history.
problem Minimizing cumulative regret in stochastic linear bandits.
method Perturbed-history exploration in a linear bandit (LinPHE) algorithm.
result Achieves a O ( d n ) O(d \sqrt{n}) O ( d n ) gap-free bound on cumulative regret. It is shown how the generating functional method of De Dominicis can be used to solve the dynamics of the original version of the minority game (MG), in which agents observe real as opposed to fake market histories. Here one again finds exact closed equations for correlation and response functions, but now these are de…
New method reduces regret in nonparametric bandits with unknown covariate shifts.
problem Optimal actions depend on context, but context distributions can change over time.
method Derives new regret bounds for nonparametric bandits under covariate shifts.
result Regret bounds adaptively attainable without knowledge of shift time or magnitude.
Custom NLP system extracts clinical data for breast cancer analysis.
problem Manual extraction of information from text-based medical records is tedious and requires specialized knowledge.
method Combines standard text mining techniques with advanced synonym detection for global analysis.
result Achieved good extraction accuracy for various concepts of interest without requiring existing corpora or ontologies.
This paper suggests claim history will be deprecated in future auto insurance rates.
problem The role of historical claim records in auto insurance rates.
method Proposes a new risk variable elimination method and real-time road risk model design.
result Claim history will be considered a 'noise' factor and deprecated in Pay-How-You-Drive models.
Improves medication name inference for telemedicine and conversational agents.
problem Challenges in mapping user-friendly medication names to standardized ones.
method Entity-boosted two-tower neural network for ranking SMN to DMP.
result State-of-the-art results achieved with improved attention-based ranking.
FLARe model forecasts Alzheimer's progression using learned latent representations.
problem Forecasting Alzheimer's disease progression at the patient level.
method Generates a sequence of latent representations from longitudinal data across multiple modalities, incorporating time horizon.
result Outperforms baseline in forecasting accuracy and F1 score, robustly handling missing visits.
We present in this chapter (Chapter II) the history of ideas which lead up to the development of modern knot theory. We are more detailed when pre-XX century history is reported. With more recent times we are more selective, stressing developments related to Jones type invariants of links. In the Appendix, A.Przybyszew…
Medical deconfounder uses EHRs to estimate treatment effects without confounders.
problem Bias in assessing treatment effects from EHRs due to unobserved confounders.
method Develops a machine learning algorithm (medical deconfounder) to adjust for confounders.
result Medical deconfounder produces more accurate treatment effect estimates and identifies effective medications.
Automated process links oral health to systemic conditions using machine learning.
problem Correlating oral health with systemic health conditions.
method Intraoral fluorescent biomarker imaging, machine learning segmentation, and clinical examination.
result Machine learning classifier achieved AUC of 0.677, indicating a learned association between disease signatures in images and periodontal disease.
PHE adds pseudo-rewards to history to minimize regret in stochastic bandits.
problem Minimizing cumulative regret in stochastic multi-armed bandits.
method PHE algorithm that adds O ( t ) O(t) O ( t ) i.i.d. pseudo-rewards to history and pulls the best arm based on the perturbed history. result Near-optimal regret bounds derived for PHE.