Novel IRL method identifies suboptimal medical decisions in ICU data.
problem Identifying suboptimal medical decisions in clinical settings.
method Incorporates Inverse Reinforcement Learning with a pruning step to identify and remove suboptimal actions.
result Pruning step effectively identifies clinical priorities and values from suboptimal data.
A new reinforcement learning method for medical decisions with limited data.
problem Learning high-performing policies from partially observed data in healthcare.
method Optimization objective that combines policy and generative model quality, suitable for batch off-policy settings.
result Demonstrated improved performance on synthetic and medical decision-making problems.
A new framework designs experiments for better decision-making.
problem Suboptimal experimental designs for downstream decision-making.
method Amortized decision-aware Bayesian Experimental Design (BED) with Transformer Neural Decision Process (TNDP).
result TNDP effectively designs experiments and facilitates accurate decision-making.
Prediction models can harm patients even when accurate, leading to self-fulfilling prophecies.
problem Prediction models can lead to harmful decisions that worsen patient outcomes.
method Formal characterization of harmful prediction models and analysis of their impact.
result Well-calibrated models are ineffective for decision-making as they do not change the data distribution.
Framework for deferring decisions to experts in sequential medical settings.
problem Myopic and non-adaptive decision-making by ML models in sequential medical contexts.
method Sequential Learning-to-Defer (SLTD) framework using model-based reinforcement learning.
result Adaptive deferral policy improves trade-off between long-term outcomes and deferral frequency.
RL algorithms with medical integration improve personalized treatment recommendations.
problem Developing effective personalized treatment strategies for chronic diseases.
method Integrating medical knowledge into RL algorithms for DTR.
result Enhanced treatment recommendations with increased confidence.
Develops new methods for risk-aware decision-making in medical bandits.
problem Risk-averse decision-making in medical contexts with limited data.
method Safe, anytime-valid concentration bounds, risk-aware contextual bandits, nonparametric algorithms.
result Improved decision-making algorithms for postoperative patient follow-up.
The paper investigates interpretability techniques for deep learning models in medical data.
problem Understanding the logic behind predictions of black-box models in medical decision-making.
method Applied deep neural networks and random forests to a medical dataset. Used autoencoders and local interpretable models to provide insights.
result Local interpretable models and autoencoders provide meaningful insights into cancer predictions, identifying distinct and non-generalizable features.
CASCADE improves uncertainty communication in Parkinson's disease medication management.
problem Uncertainty in clinical decision-making for Parkinson's disease patients.
method CASCADE uses a novel conformal prediction framework to adaptively scale prediction intervals based on classification uncertainty.
result CASCADE produces more efficient and robust prediction intervals for Parkinson's disease patients.
Paper shows how to quantify uncertainty in medical ML models.
problem Uncertainty in opaque ML models can lead to safety risks in medical applications.
method Introduces Uncertainty Wrapper to quantify uncertainty transparently.
result Demonstrates practical utility of Uncertainty Wrapper in flow cytometry.
Paper uses ML to classify liver diseases from clinical data.
problem Classifying liver diseases from clinical data.
method Multiple imputation, PCA, data visualizations, binary classifier algorithms (ANN, RF, SVM).
result SVM showed better accuracy (98.23%).
This study applies neural models to automatically recognize medical entities from natural language.
problem Automated recognition of medical entities from natural language is complex and time-consuming.
method Utilizes deep neural sequence models trained on a large dataset of death certificates.
result Deep neural models can efficiently recognize medical entities from natural language.
Patient journeys are compared to find clusters of similar disease trajectories.
problem Discovering shared health outcomes among patient journeys.
method Comparing longitudinal health data to identify clusters of similar patient trajectories.
result Clusters of patient journeys with similar health outcomes can be identified.
Paper uses AI to improve medical diagnosis accuracy.
problem Improving accuracy of medical diagnoses.
method Heuristic frequentist and Bayesian approaches applied to a nationwide dataset.
result Algorithm outperforms human doctors in detecting abnormal births.
Study proposes a statistical test for Vision Transformer's attention mechanisms.
problem ViT's attention mechanisms may focus on irrelevant regions, leading to unreliable evidence.
method Selective inference framework to quantify statistical significance of attentions as p-values.
result Proposed method enables reliable quantification of false positive detection probability of attentions.
The paper investigates deep neural networks for medical imaging applications, providing interpretable results.
problem Uninterpretable decisions made by deep neural networks in medical imaging applications.
method Investigation of deep neural networks for malaria, diabetic retinopathy, brain tumor, and tuberculosis detection in various imaging modalities. Visualization of class activation mappings provided.
result Visualization of class activation mappings enhances understanding of deep neural networks and aids doctors in decision-making.
GPs' decisions can vary significantly with different kernels, even if kernels are qualitatively similar.
problem Robustness of GP decisions to kernel choice.
method Solved a constrained optimization problem over a finite-dimensional space to identify changes in GP decisions.
result Decisions made with a GP can be non-robust to kernel choice, even with qualitatively similar kernels.
FIGS improves prediction performance while maintaining interpretability, especially in medical domains.
problem Lack of interpretability in machine learning models, particularly in high-stakes domains like medicine.
method Generalizes CART algorithm to grow multiple trees in summation, combining logical rules with addition.
result FIGS achieves state-of-the-art prediction performance and derives interpretable clinical decision instruments (CDIs).
CPR models complex decision processes by breaking them into context-specific policies, improving interpretability and accuracy.
problem Interpreting dynamic human decision-making processes in medical contexts.
method Develops Contextualized Policy Recovery (CPR) framework for multi-task learning, modeling each context-specific policy as a linear map.
result Achieves state-of-the-art performance in predicting medical decisions, closing the gap between interpretable and black-box methods.
Optimal decision-making using prediction sets to minimize risk.
problem Using prediction sets optimally for decision-making in uncertain scenarios.
method Decision-theoretic framework that seeks to minimize expected loss against a worst-case distribution.
result ROCP algorithm reduces critical mistakes compared to baselines, especially in costly out-of-set errors.
In most real-world settings such as recommender systems, finance, and healthcare, collecting useful information is costly and requires an active choice on the part of the decision maker. The decision-maker needs to learn simultaneously what observations to make and what actions to take. This paper incorporates the info…
Machine learning can help personalized decision support by learning models to predict individual treatment effects (ITE). This work studies the reliability of prediction-based decision-making in a task of deciding which action a to take for a target unit after observing its covariates x~ and predicted outcom…
A model for human-machine decision-making with private info and opacity.
problem Optimizing decisions in a human-machine system with private info and opacity.
method Formulated as a two-player learning problem, proved lower and upper bounds on optimality.
result Simple coordination strategy is nearly minimax optimal, efficient learning possible under certain assumptions.
Paper detects bias in AI medical models using CART.
problem Ensuring fairness in AI medical decision support systems.
method Uses Classification and Regression Trees (CART) algorithm to identify bias.
result Validated the CART approach in both synthetic and real-world data.
Simplifies decision-making during medical exams with cost-efficient feature acquisition.
problem Guiding physicians during examination acquisition for accurate and efficient diagnosis.
method Dropout at input layer and integrated gradients at test-time for dynamic feature importance.
result More cost- and feature-efficient than prior approaches, achieving higher overall accuracy.
A primary goal of computational phenotype research is to conduct medical diagnosis. In hospital, physicians rely on massive clinical data to make diagnosis decisions, among which laboratory tests are one of the most important resources. However, the longitudinal and incomplete nature of laboratory test data casts a sig…
Visual analytics system for comparing medical records using sequence embeddings.
problem Challenges in analyzing medical records due to high dimensionality, irregularity, and sparsity.
method Event and sequence embeddings using autoencoder and self-attention mechanism, with sequence alignment for comparison.
result Demonstrated effectiveness with real-world neonatal ICU dataset.
IML methods improve survival analysis transparency.
problem Limited interpretability in survival analysis models.
method Adapting IML techniques to survival analysis.
result Enhanced understanding of model predictions and risks.
A contextual care protocol is used by a medical practitioner for patient healthcare, given the context or situation that the specified patient is in. This paper proposes a method to build an automated self-adapting protocol which can help make relevant, early decisions for effective healthcare delivery. The hybrid mode…
New method quantifies uncertainty at class level for better decision-making.
problem Improving cost-sensitive decision-making in classification tasks.
method Label-wise decomposition of uncertainty measures based on non-categorical metrics.
result Proposed measures adhere to desirable properties and improve uncertainty quantification.
Develops a new RL algorithm for medical treatment regimes.
problem Optimal dose determination in continuous action environments.
method Quasi-optimal learning algorithm for near-optimal actions.
result Guaranteed convergence and effectiveness in real applications.
AI-Interpret transforms opaque policies into simple, interpretable decision rules.
problem Designing effective decision aids for professionals to mitigate decision-making biases.
method Combining imitation learning, program induction, and clustering to transform learned policies into interpretable descriptions.
result Providing interpretable decision rules as flowcharts significantly improves people's planning strategies and decisions.
Mining relationships between treatment(s) and medical problem(s) is vital in the biomedical domain. This helps in various applications, such as decision support system, safety surveillance, and new treatment discovery. We propose a deep learning approach that utilizes both word level and sentence-level representations …
Enhances uncertainty estimation in medical image segmentation.
problem Frequency-related noise in medical imaging leads to biased uncertainty estimates.
method Extends MC-Dropout to the frequency domain for better uncertainty estimation.
result MC-Frequency Dropout improves calibration and uncertainty in semantic segmentation.
In this work, we investigate unsupervised representation learning on medical time series, which bears the promise of leveraging copious amounts of existing unlabeled data in order to eventually assist clinical decision making. By evaluating on the prediction of clinically relevant outcomes, we show that in a practical …
Method interprets deep learning models using topological data analysis.
problem Lack of interpretability in deep learning models, especially in high-risk applications.
method Topological and geometric data analysis to infer features and decision-making mechanisms of DL models.
result Extracted subgraphs reveal relevant features for model decisions, demonstrating model's reliance on pertinent data.
Modern medicine requires generalised approaches to the synthesis and integration of multimodal data, often at different biological scales, that can be applied to a variety of evidence structures, such as complex disease analyses and epidemiological models. However, current methods are either slow and expensive, or inef…
Deep Bayesian models estimate causal effects for dynamic treatment regimes over long follow-up times.
problem Challenges in causal effect estimation for dynamic treatment regimes with long follow-up times.
method Combining outcome regression models with deep Bayesian models for high-dimensional features.
result Stable and accurate dynamic causal effect estimation from observational data, especially with long-term follow-up.
Method learns evolving policies in healthcare contexts.
problem Understanding non-stationary behavior in evolving decision-making processes.
method Inverse Contextual Bandits (ICB) approach for learning interpretable representations of non-stationary behavior.
result Demonstrated applicability and accuracy of ICB method in liver transplantation policies.
Introduction. Case Based Reasoning (CBR) is an emerg- ing decision making paradigm in medical research where new cases are solved relying on previously solved similar cases. Usually, a database of solved cases is provided, and every case is described through a set of attributes (inputs) and a label (output). Extracting…
A reinforcement learning method predicts medical outcomes from masked feature vectors.
problem Predicting medical outcomes from limited feature data.
method Reinforcement learning with iterative feature selection and a guesser network.
result The method outperforms baselines and is highly interpretable.
Proposes a method to quantify uncertainty in DNN models for discrete inputs.
problem Uncertainty quantification for DNN models with categorical and discrete feature variables.
method Develops a mathematical framework to quantify prediction uncertainty from discrete input noise and model parameters.
result Identifies risk-sensitive cases prone to misclassification due to discrete predictor errors.
Deep learning skin lesion classifier explained using CAVs.
problem Limited acceptance of deep learning CAD systems due to opaque decision-making.
method Mapped human understandable concepts to RECOD model using CAVs.
result Classifier learns and encodes disease-related concepts in its latent representation.
This guide explains statistical distances for evaluating generative models.
problem Evaluating the quality of samples from generative models.
method Four statistical distances: SW, C2ST, MMD, FID.
result Different distances can yield varying results on similar data.
The study evaluates AI model performance measures for medical use.
problem Selecting appropriate performance measures for AI models in medical practice.
method Assessed 32 performance measures across five domains for binary outcomes.
result 17 measures are both proper and reflect decision-analytic performance.
Explanations for deep neural network predictions in terms of domain-related concepts can be valuable in medical applications, where justifications are important for confidence in the decision-making. In this work, we propose a methodology to exploit continuous concept measures as Regression Concept Vectors (RCVs) in th…
This work advances collaborative decision making by combining human and AI strengths in uncertainty quantification.
problem Current AI lacks robust decision-making capabilities under uncertainty, especially in high-stakes contexts.
method Introduces Human AI Collaborative Uncertainty Quantification (HACUQ) framework, formalizing AI-human collaboration and developing calibration algorithms.
result Optimal collaborative prediction sets follow a two-threshold structure, and online adaptation algorithms can adapt to evolving human behavior.
Method trains neural network for optimal decisions from stochastic simulators.
problem Suboptimal decisions from SBI approximations of posterior distributions.
method Trains neural network on simulated data to predict optimal actions.
result Induces similar cost as true posterior for optimal actions.