Computed tomography (CT) examinations are commonly used to predict lung nodule malignancy in patients, which are shown to improve noninvasive early diagnosis of lung cancer. It remains challenging for computational approaches to achieve performance comparable to experienced radiologists. Here we present NoduleX, a syst…
On-device research index
arXiv research
A locally-built, LLM-digested index of recent arXiv papers in quant finance, geometry/topology, and statistical ML — keyword search served straight from SQLite on this machine.
168,878 papers · 148 categories
Trend · papers per month
48 results for “malignancy prediction”
Deep CNN model improves breast cancer screening exam classification.
problem Improving accuracy in breast cancer screening exam classification.
method Localization-based deep CNN trained on 200,000 exams.
result AUC of 0.919 in predicting malignancy, reducing error rate by 23%.
X-Caps improves medical diagnosis explainability by encoding visual attributes in capsules.
problem Uninterpretable predictions from deep neural networks in healthcare.
method Teaches a novel multi-task capsule network to encode high-level visual attributes and malignancy scores.
result X-Caps outperforms state-of-the-art deep dense 3D CNNs in capturing visually interpretable attributes and malignancy prediction.
We explore several oversampling techniques for an imbalanced multi-label classification problem, a setting often encountered when developing models for Computer-Aided Diagnosis (CADx) systems. While most CADx systems aim to optimize classifiers for overall accuracy without considering the relative distribution of each …
Prediction of Malignant & Benign Breast Cancer: A Data Mining Approach in Healthcare Applicationscs.LG
As much as data science is playing a pivotal role everywhere, healthcare also finds it prominent application. Breast Cancer is the top rated type of cancer amongst women; which took away 627,000 lives alone. This high mortality rate due to breast cancer does need attention, for early detection so that prevention can be…
This study predicts ovarian cancer from cysts using TVUS and machine learning.
problem Early detection of ovarian cancer from cysts using TVUS screening.
method Employed Random Forest, KNN, and XGBoost machine learning techniques on PLCO dataset.
result Achieved high accuracy, recall, f1 score, and precision in predicting ovarian cancer.
Improved breast cancer screening with a fast, memory-efficient model.
problem Classifying high-resolution breast cancer screening images.
method Extends globally-aware multiple instance classifier to handle image-level labels.
result Achieves AUC of 0.93 in classifying malignant findings, outperforming existing methods.
New biomarker predicts MRgFUS treatment outcome without contrast agents.
problem Inaccurate assessment of treated tissue viability after MRgFUS.
method Deep learning on noncontrast multiparametric MRI images, voxel-wise registration.
result Predicted follow-up NPV with DICE coefficient 0.71, outperforming current standard.
Identification of Cancer -- Mesothelioma Disease Using Logistic Regression and Association Rulecs.CY
Malignant Pleural Mesothelioma (MPM) or malignant mesothelioma (MM) is an atypical, aggressive tumor that matures into cancer in the pleura, a stratum of tissue bordering the lungs. Diagnosis of MPM is difficult and it accounts for about seventy-five percent of all mesothelioma diagnosed yearly in the United States of …
Characterization of lung nodules as benign or malignant is one of the most important tasks in lung cancer diagnosis, staging and treatment planning. While the variation in the appearance of the nodules remains large, there is a need for a fast and robust computer aided system. In this work, we propose an end-to-end tra…
New models compare mammograms to improve cancer diagnosis.
problem Improving cancer diagnosis accuracy by comparing recent and prior mammograms.
method Proposed neural network models trained on over 665,000 pairs of images.
result Best model achieves AUC of 0.866 in predicting malignancy.
Purpose: Lung nodules have very diverse shapes and sizes, which makes classifying them as benign/malignant a challenging problem. In this paper, we propose a novel method to predict the malignancy of nodules that have the capability to analyze the shape and size of a nodule using a global feature extractor, as well as …
Cervical cancer is the leading gynecological malignancy worldwide. This paper presents diverse classification techniques and shows the advantage of feature selection approaches to the best predicting of cervical cancer disease. There are thirty-two attributes with eight hundred and fifty-eight samples. Besides, this da…
The paper detects and identifies bias in data using a counterfactual approach.
problem Detecting and identifying bias in data, especially in medical image classification.
method A global explanation framework using the counterfactual approach to identify bias causing artifacts.
result Black frames significantly influence Convolutional Neural Network's prediction, changing benign to malignant.
New method uses probabilistic independence to discover disease signatures from medical records.
problem Insufficiently precise diagnosis of clinical disease leading to treatment failures.
method Unsupervised machine learning using probabilistic independence to disentangle disease patterns.
result Inferred 2000 clinical disease signatures from medical records, improving cancer prediction.
An Overview of Melanoma Detection in Dermoscopy Images Using Image Processing and Machine Learningcs.CV
The incidence of malignant melanoma continues to increase worldwide. This cancer can strike at any age; it is one of the leading causes of loss of life in young persons. Since this cancer is visible on the skin, it is potentially detectable at a very early stage when it is curable. New developments have converged to ma…
Recent studies have shown promising results in using Deep Learning to detect malignancy in whole slide imaging. However, they were limited to just predicting positive or negative finding for a specific neoplasm. We attempted to use Deep Learning with a convolutional neural network algorithm to build a lymphoma diagnost…
We present a deep convolutional neural network for breast cancer screening exam classification, trained and evaluated on over 200,000 exams (over 1,000,000 images). Our network achieves an AUC of 0.895 in predicting whether there is a cancer in the breast, when tested on the screening population. We attribute the high …
Mammography is the most effective and available tool for breast cancer screening. However, the low positive predictive value of breast biopsy resulting from mammogram interpretation leads to approximately 70% unnecessary biopsies with benign outcomes. Data mining algorithms could be used to help physicians in their dec…
Radiological imaging of the prostate is becoming more popular among researchers and clinicians in searching for diseases, primarily cancer. Scans might be acquired with different equipment or at different times for prognosis monitoring, with patient movement between scans, resulting in multiple datasets that need to be…
New bounds for linear interpolators show how they generalize under covariate shifts.
problem Understanding how linear interpolators generalize under covariate shifts.
method Proved non-asymptotic excess risk bounds for benignly-overfit linear interpolators in transfer learning.
result Identified beneficial and malignant covariate shifts based on overparameterization degree.
PersonalizedUS assesses breast cancer risk with local coverage guarantees.
problem Manual BI-RADS scoring leads to unnecessary biopsies and mental health burden.
method Conformal prediction for precise, personalized risk estimates.
result Local coverage guarantees with high sensitivity and specificity.
In order for machine learning to be deployed and trusted in many applications, it is crucial to be able to reliably explain why the machine learning algorithm makes certain predictions. For example, if an algorithm classifies a given pathology image to be a malignant tumor, then the doctor may need to know which parts …
Proposes BGNN for tumor heterogeneity prediction using graph neural networks.
problem Tumor classification limitations and heterogeneity assessment challenges.
method Artificial data generation, tumor heterogeneity estimation, and BGNN model development.
result BGNN achieves accuracy in predicting tumor heterogeneity.
The study of high-throughput genomic profiles from a pharmacogenomics viewpoint has provided unprecedented insights into the oncogenic features modulating drug response. A recent screening of ~1,000 cancer cell lines to a collection of anti-cancer drugs illuminated the link between genotypes and vulnerability. However,…
Study uses multi-task Bayesian optimization to speed up SVM hyperparameter tuning for nodules diagnosis.
problem Redundant and time-consuming hyperparameter tuning for SVM classifiers in medical imaging.
method Employed multi-task Bayesian optimization to accelerate hyperparameter search.
result Multi-task Bayesian optimization significantly accelerates hyperparameter search.
Lung cancer is the leading cause of cancer-related death worldwide. Early diagnosis of pulmonary nodules in Computed Tomography (CT) chest scans provides an opportunity for designing effective treatment and making financial and care plans. In this paper, we consider the problem of diagnostic classification between beni…
Proposes ConRad model for lung cancer classification using radiomics and interpretable machine learning.
problem Lack of interpretability in deep neural networks for cancer diagnosis.
method Integration of radiomics and DNN-predicted biomarkers in interpretable classifiers (ConRad).
result ConRad models outperform CNNs in five-fold cross-validation.
This paper reports the method and evaluation results of MedAusbild team for ISIC challenge task. Since early 2017, our team has worked on melanoma classification [1][6], and has employed deep learning since beginning of 2018 [7]. Deep learning helps researchers absolutely to treat and detect diseases by analyzing medic…
Deep-MIL models fail to respect key MIL assumption, leading to incorrect learning.
problem Deep-MIL models learn anti-correlated instances, violating the standard MIL assumption.
method Proposed algorithmic unit tests to identify violations of MIL assumptions.
result Five prominent deep-MIL models fail algorithmic unit tests, revealing incorrect learning.
CDAM improves attention maps for ViTs, making them more class-sensitive.
problem Existing attention maps in ViTs lack class sensitivity.
method Class-discriminative attention maps (CDAM) that scale attention scores by class relevance.
result CDAM provides more class-sensitive explanations than existing methods.
Deep learning predicts breast cancer with high accuracy from patient data.
problem Early detection of breast cancer from patient data.
method Feature selection and k-fold Monte Carlo cross-validation using deep learning.
result Deep learning model effectively distinguishes between cancer and healthy patients.
Gliomas are the most common primary brain malignancies, with different degrees of aggressiveness, variable prognosis and various heterogeneous histologic sub-regions, i.e., peritumoral edematous/invaded tissue, necrotic core, active and non-enhancing core. This intrinsic heterogeneity is also portrayed in their radio-p…
Neural network improves breast cancer diagnosis with high accuracy.
problem Improving accuracy in breast cancer diagnosis.
method Higher-order probabilistic perceptron (HOPP) model.
result HOPP model achieves up to 97% accuracy in classifying breast cancer tumors.
Convolutional Neural Networks (CNNs) require a large amount of annotated data to learn from, which is often difficult to obtain in the medical domain. In this paper we show that the sample complexity of CNNs can be significantly improved by using 3D roto-translation group convolutions (G-Convs) instead of the more conv…
Machine learning classifies colorectal tissue using photoacoustic microscopy.
problem Traditional diagnostic methods for colorectal cancer are limited in detail and painful.
method Machine learning applied to acoustic resolution photoacoustic microscopy.
result Machine learning accurately classified benign and malignant tissue.
Deep learning models designed for visual classification tasks on natural images have become prevalent in medical image analysis. However, medical images differ from typical natural images in many ways, such as significantly higher resolutions and smaller regions of interest. Moreover, both the global structure and loca…
Flexible variable selection handles missing data for better biomarker panels.
problem Identifying relevant features from incomplete data sets.
method Nonparametric variable selection combined with multiple imputation.
result Improved biomarker panels with higher classification and variable selection performance.
We might hope that when faced with unexpected inputs, well-designed software systems would fire off warnings. Machine learning (ML) systems, however, which depend strongly on properties of their inputs (e.g. the i.i.d. assumption), tend to fail silently. This paper explores the problem of building ML systems that fail …
A Mixture of Views Network with Applications to the Classification of Breast Microcalcificationscs.CV
In this paper we examine data fusion methods for multi-view data classification. We present a decision concept which explicitly takes into account the input multi-view structure, where for each case there is a different subset of relevant views. This data fusion concept, which we dub Mixture of Views, is implemented by…
GeoTop resolves topological ambiguity in diagnostic imaging using geometric-topological analysis.
problem Topological equivalence between benign and malignant structures in diagnostic images.
method Combines Topological Data Analysis and Lipschitz-Killing Curvatures to resolve ambiguity.
result Achieves 3.6% accuracy improvement and reduces false positives/negatives by 15-18%.
Interpolation can prevent classifiers from having desired invariance properties.
problem Invariance properties in over-parameterized models are often ineffective.
method Theoretical analysis and algorithm design for non-interpolating classifiers.
result Interpolating classifiers cannot satisfy desired invariance properties.
We introduce a graph-theoretic approach to extract clusters and hierarchies in complex data-sets in an unsupervised and deterministic manner, without the use of any prior information. This is achieved by building topologically embedded networks containing the subset of most significant links and analyzing the network s…
We correct for sampling bias in training models to improve real-world performance.
problem Sampling bias causes discrepancies between lab and real-world model performance.
method Bayesian risk minimization and derived bias-corrected loss functions.
result Our approach integrates seamlessly into current learning paradigms and improves model performance.
There are various algorithms and methodologies used for automated screening of cervical cancer by segmenting and classifying cervical cancer cells into different categories. This study presents a critical review of different research papers published that integrated AI methods in screening cervical cancer via different…
Generative Synthetic Augmentation using Label-to-Image Translation for Nuclei Image Segmentationcs.LG
This paper proposes synthetic augmentation for nuclei image segmentation in medical pathology.
problem Rare and time-consuming labeling of tumor nuclei images for semantic segmentation.
method Label-to-image translation to generate synthetic images.
result Synthetic augmentation improves segmentation accuracy.
Flow cytometry is often used to characterize the malignant cells in leukemia and lymphoma patients, traced to the level of the individual cell. Typically, flow cytometric data analysis is performed through a series of 2-dimensional projections onto the axes of the data set. Through the years, clinicians have determined…
Different types of Convolutional Neural Networks (CNNs) have been applied to detect cancerous lung nodules from computed tomography (CT) scans. However, the size of a nodule is very diverse and can range anywhere between 3 and 30 millimeters. The high variation of nodule sizes makes classifying them a difficult and cha…