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arXiv research

A locally-built, LLM-digested index of recent arXiv papers in quant finance, geometry/topology, and statistical ML — keyword search served straight from SQLite on this machine.

168,657 papers · 148 categories

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48 results for longitudinal EHR data

Develops algorithm to find subgroups with different treatment effects in HIV patients.

problem Estimating treatment effects in EHR data with challenges like time-varying confounding.
method SDLD algorithm combining generalized interaction tree and longitudinal targeted maximum likelihood estimation.
result Identifies subgroups of HIV patients at higher risk of weight gain with dolutegravir-containing ARTs.

Proposes Ada-Sit method for mortality prediction of rare diseases.

problem Data insufficiency and clinical diversity of rare diseases make mortality prediction hard.
method Initialization-sharing multi-task learning method (Ada-Sit) for fast adaptation to similar tasks.
result Experimental results show the proposed model is effective for mortality prediction of diverse rare diseases.

This paper reviews methods for discovering patient subgroups from EHR data.

problem Discovering subgroups of patients and co-occurring medical conditions from EHR data.
method Low-rank data approximation methods like matrix and tensor decompositions.
result These methods provide transparent and interpretable insights into patient phenotypes.

Novel framework detects CKD in diabetic patients using sparse EHR representations.

problem Early detection of CKD in diabetic patients.
method Sparse longitudinal representations of EHR data.
result Proposed model achieves higher predictive performance than baselines.

This article presents a novel method for predicting suicidal ideation from Electronic Health Records (EHR) and Ecological Momentary Assessment (EMA) data using deep sequential models. Both EHR longitudinal data and EMA question forms are defined by asynchronous, variable length, randomly-sampled data sequences. In our …

2019-11-06abs ↗pdf ↗

Electronic health records (EHR) data provide a cost and time-effective opportunity to conduct cohort studies of the effects of multiple time-point interventions in the diverse patient population found in real-world clinical settings. Because the computational cost of analyzing EHR data at daily (or more granular) scale…

2017-05-27abs ↗pdf ↗

Missing data is a common problem in real-world settings and particularly relevant in healthcare applications where researchers use Electronic Health Records (EHR) and results of observational studies to apply analytics methods. This issue becomes even more prominent for longitudinal data sets, where multiple instances …

2018-12-02abs ↗pdf ↗

In this paper we present a Recurrent neural networks (RNN) based architecture that achieves an AUCROC of 0.9147 for predicting the onset of Congestive Heart Failure (CHF) 15 months in advance using a 12-month observation window on a large cohort of 216,394 patients. We believe this to be the largest study in CHF onset …

2019-02-07abs ↗pdf ↗

Neural network predicts cardiovascular events from EHRs with high accuracy.

problem Predicting onset of cardiovascular diseases from electronic health records.
method Multi-task gated recurrent units with attention mechanism.
result Model outperforms clinical risk scores in predicting stroke and myocardial infarction.

Scoping review and benchmarking of synthetic EHR data generation methods.

problem Creating realistic synthetic electronic health records for research and training.
method Conducted a scoping review and benchmarked seven methods on open-source EHR datasets.
result GAN-based methods excel in fidelity and utility, while rule-based methods excel in privacy protection.

SurvLatent ODE predicts VTE risk for cancer patients, outperforming current methods.

problem Predicting clinical outcomes from irregularly sampled EHR data with competing events.
method Neural ODE-based Recurrent Neural Networks (ODE-RNN) for flexible survival time estimation.
result SurvLatent ODE outperforms Khorana Risk scores for VTE risk prediction.

Proposes a method to derive knowledge graphs from EHR data.

problem Challenges in deriving generalizable knowledge from EHR data.
method Infer conditional dependency structure via a latent graphical block model (LGBM).
result Perfect recovery of block structure demonstrated.

A tutorial on various methods for clustering longitudinal data.

problem Identifying groups with different trends in longitudinal data.
method Group-based trajectory modeling, growth mixture modeling, longitudinal k-means.
result Strengths, limitations, and model extensions of the methods are discussed.

Novel imputation method for EHRs with structured and sporadic missingness.

problem Missing data in integrated EHR datasets for clinical applications.
method Macomss, a novel imputation framework for structurally and heterogeneously missing data.
result Macomss outperforms existing methods in imputation and downstream prediction accuracy.

Paper proposes multimodal contrastive learning for EHR data.

problem Separate treatment of structured and unstructured EHR data.
method Proposes a multimodal feature embedding generative model and a multimodal contrastive loss.
result Multimodal learning yields better feature representation than single-modality learning.

LPCI provides valid prediction intervals for longitudinal data.

problem Current conformal prediction methods for time series data lack cross-sectional coverage when applied to longitudinal datasets.
method Modeling residual data as a quantile fixed-effects regression problem, constructing prediction intervals with a trained quantile regressor.
result LPCI achieves valid cross-sectional coverage and outperforms existing benchmarks in terms of longitudinal coverage rates.

WEST uses EHRs and expert cases to improve rare disease phenotyping.

problem Limited labeled data for rare diseases.
method Weakly supervised transformer model trained on probabilistic silver-standard labels.
result WEST outperforms existing methods in phenotype classification and subphenotyping.

Study proposes a multimodal model for cardiovascular risk prediction using EHRs.

problem Lack of comprehensive risk prediction from EHRs due to unstructured text.
method Proposes a multimodal BiLSTM model integrating structured and unstructured EHR data.
result Proposed BiLSTM model outperforms other DNN architectures in cardiovascular risk prediction.

This work generates synthetic EHRs with privacy guarantees for machine learning tasks.

problem Privacy concerns and heterogeneity in EHR data limit their use in machine learning.
method Generative Adversarial Networks (GANs) with differential privacy (DP) for synthetic data generation.
result Synthetic EHRs maintain performance close to real data, even with DP applied.

PEHRT harmonizes EHR data for translational research.

problem Barriers in using EHR data for translational research.
method Common pipeline including open-source code, visualization tools, and detailed documentation.
result PEHRT harmonizes EHR data to standardized ontologies and generates robust embeddings.

Framework harmonizes EHR data across institutions for better analysis.

problem Heterogeneity of medical codes and terminologies hinder EHR data analysis.
method MASH (Multi-source Automated Structured Hierarchy) uses neural optimal transport and learned hyperbolic embeddings to align and structure EHR data.
result MASH generates interpretable hierarchical graphs for unstructured local laboratory codes.

Study finds multi-task learning and pre-training can improve healthcare models on EHR data.

problem Improving model performance on diverse EHR tasks using multi-task learning.
method Examined multi-task learning across various EHR tasks and training schemes, using pre-training and fine-tuning.
result Significant gains in model performance achieved via multi-task pre-training and single-task fine-tuning.

New method models longitudinal data using variational inference and normalizing flows.

problem Handling high-dimensional longitudinal data with time dependency.
method Variational inference with normalizing flows for latent variables.
result The method achieves better likelihood estimates and more reliable missing data imputation.