Estimates long-term effects of new treatments using historical and short-term data.
problem Estimating long-term effects of novel treatments with limited historical data.
method Surrogate indices, dynamic treatment effect estimation, and double machine learning combined in a unified pipeline.
result Consistent and asymptotically normal estimates of long-term effects under Markovian assumption.
Paper uses RL to estimate long-term treatment effects efficiently.
problem Estimating long-term treatment effects in nonstationary settings.
method Reinforcement Learning (RL) for Markov processes.
result Demonstrated promising results in synthetic and real-world datasets.
The paper addresses estimating long-term treatment effects with monotone missing data.
problem Estimating long-term treatment effects with missing data, especially monotone missing.
method The paper introduces the sequential missingness assumption for identification and proposes three novel estimation methods: inverse probability weighting, sequential regression imputation, and SeqMSM. It also introduces a balancing-enhanced approach, BalanceNet, to improve estimation accuracy.
result The proposed methods, including BalanceNet, effectively estimate long-term treatment effects with monotone missing data.
The paper tackles long-term treatment effects with persistent confounders using sequential short-term outcomes.
problem Estimating long-term treatment effects with persistent unmeasured confounders.
method Exploiting the sequential structure of short-term outcomes, the paper develops three novel identification strategies and corresponding estimators.
result The proposed methods outperform existing approaches in handling persistent confounders.
New LT-O-learners improve HLTE estimation with low overlap.
problem Challenges in estimating heterogeneous long-term treatment effects due to limited overlap.
method Introduces LT-O-learners that use custom overlap weights to downweight low-overlap samples.
result LT-O-learners provide robust HLTE estimates with lower variance in low-overlap regimes.
New framework for choosing optimal proxy metrics from past experiments.
problem Difficult to measure long-term treatment effects in experiments.
method Statistical framework to define and construct optimal proxy metrics.
result Optimal proxy metric depends on experiment's sample size.
Estimating the long-term effects of treatments is of interest in many fields. A common challenge in estimating such treatment effects is that long-term outcomes are unobserved in the time frame needed to make policy decisions. One approach to overcome this missing data problem is to analyze treatments effects on an int…
Combining experimental and observational data for long-term causal effects.
problem Estimating causal effects of treatment on long-term outcomes using mixed data types.
method Three approaches for fusing experimental and observational data: equal confounding, shared confounder, and proxy variables.
result Developed estimators for each approach and analyzed their robustness.
Study estimates long-term effects of online advertising mechanisms on user behavior and revenue.
problem Estimating long-term treatment effects in online advertising systems.
method Modeling treatment effects as a stopped random walk, using experimental design, and statistical methods.
result Confidence intervals for long-term treatment effects constructed using statistical techniques.
Improves A/B testing for long-term outcomes in dynamic systems.
problem Estimating long-term effects from short-term A/B testing data.
method Develops optimal inference techniques and localized information sharing methods.
result New estimator reduces variance linearly with test arms and matches lower bounds.
Deep Bayesian models estimate causal effects for dynamic treatment regimes over long follow-up times.
problem Challenges in causal effect estimation for dynamic treatment regimes with long follow-up times.
method Combining outcome regression models with deep Bayesian models for high-dimensional features.
result Stable and accurate dynamic causal effect estimation from observational data, especially with long-term follow-up.
Bayesian optimization for long-term outcomes using fast and slow experiments.
problem Optimizing long-term system effects with short-term misleading results.
method Combining fast and slow experiments for Bayesian optimization.
result Sequential optimization over large action spaces in a short time.
Proposes a model to estimate treatment effects in complex multiagent systems over time.
problem Challenges in evaluating interventions in multiagent systems, especially with time-varying relationships and covariates.
method Interpretable counterfactual recurrent network leveraging graph variational recurrent neural networks and domain knowledge.
result Achieved lower estimation errors and more effective treatment timing than baselines in simulated and real-world scenarios.
This paper introduces a reinforcement learning framework for A/B testing with dynamic causal effects.
problem Challenges in online experiments with sequential treatments and long-term impacts.
method Reinforcement learning framework for sequential monitoring and updating.
result Demonstrates improved treatment effect evaluation over current methods.
Estimates long-term effects from short-term experiments and observational data with unobserved confounders.
problem Estimating long-term causal effects from short-term experiments and long-term observational data with unobserved confounding.
method Combining regression residuals with short-term experimental outcomes to create an instrumental variable for estimating long-term causal effects.
result The estimator is unbiased and its variance is analytically studied.
New methods for estimating complex causal effects in econometrics.
problem Estimating causal parameters in short panel data models using nested nonparametric instrumental variable regression.
method Introducing techniques to limit ill-posedness in nested NPIV, providing explicit mean square rates and efficient inference.
result Explicit mean square rates for nested NPIV and efficient inference for causal parameters.
Study uses surrogate data to improve treatment effect estimation with scarce outcome data.
problem Limited outcome data hinders estimating treatment effects.
method Uses abundant surrogate data to estimate treatment effects without stringent assumptions.
result Improves precision of treatment effect estimation.
New method for estimating treatment effects without complex propensity models.
problem Estimating treatment effects in dynamic treatment regimes.
method Recursive Riesz representer estimation for de-biasing corrections.
result Directly estimates de-biasing corrections without auxiliary models.
We propose a comprehensive treatment of the leverage effect, i.e. the relationship between returns and volatility of a specific asset, focusing on energy commodities futures, namely Brent and WTI crude oils, natural gas and heating oil. After estimating the volatility process without assuming any specific form of its b…
GEAR uses auxiliary data to estimate optimal decisions in studies with limited primary outcomes.
problem Estimating optimal decisions when primary outcomes are not available in experimental samples.
method GEAR uses augmented inverse propensity weighting to estimate optimal decisions based on auxiliary data.
result GEAR estimators and value estimators have established asymptotic properties and are validated in simulations and a real application.
The paper learns personalized treatment rules from observational data.
problem Developing effective treatment policies for individual patients.
method Contextual bandit approach to minimize expected risk of treatment policies.
result The proposed method outperforms physicians and baseline approaches in IV and VP administration.
We consider the problem of constructing diffusion operators high dimensional data X to address counterfactual functions F, such as individualized treatment effectiveness. We propose and construct a new diffusion metric KF that captures both the local geometry of X and the directions of variance of F. The res…
Much attention has been devoted recently to the development of machine learning algorithms with the goal of improving treatment policies in healthcare. Reinforcement learning (RL) is a sub-field within machine learning that is concerned with learning how to make sequences of decisions so as to optimize long-term effect…
The paper targets optimal interventions for long-term outcomes using imputed data and policy learning.
problem Maximizing long-term outcomes observed only in the future.
method Imputing missing long-term outcomes and using a doubly-robust approach for policy evaluation and optimization.
result The approach outperforms simple short-term proxies and achieves significant revenue impact over three years.
Machine-assisted treatment recommendations hold a promise to reduce physician time and decision errors. We formulate the task as a sequence-to-sequence prediction model that takes the entire time-ordered medical history as input, and predicts a sequence of future clinical procedures and medications. It is built on the …
Organic updates (from a member's network) and sponsored updates (or ads, from advertisers) together form the newsfeed on LinkedIn. The newsfeed, the default homepage for members, attracts them to engage, brings them value and helps LinkedIn grow. Engagement and Revenue on feed are two critical, yet often conflicting ob…
Kernel method estimates long-term effects from short-term data.
problem Estimating long-term effects from short-term data in continuous actions.
method Kernel ridge regression to embed and extrapolate long-term effects.
result Uniform consistency and nonasymptotic error bounds for the estimator.
The biological processes involved in a drug's mechanisms of action are oftentimes dynamic, complex and difficult to discern. Time-course gene expression data is a rich source of information that can be used to unravel these complex processes, identify biomarkers of drug sensitivity and predict the response to a drug. H…
M3E2 neural network estimates multiple treatment effects.
problem Estimating effects of multiple treatments simultaneously.
method Multi-task learning neural network model for multiple treatments, continuous and binary.
result M3E2 outperforms baselines in synthetic datasets.
Proposes a new method to estimate continuous treatment policies and match treatments effectively.
problem Current methods struggle with continuous treatment policies and complex matching.
method Formulates treatment effectiveness as a parametrizable model, using deep learning for optimization.
result Significant improvement in treatment effectiveness and matching efficiency.
SAFER improves personalized treatment recommendations for dynamic clinical contexts.
problem Personalized treatment optimization in evolving clinical contexts with safety concerns.
method Integrates structured EHR and clinical notes, uses conformal prediction for safe recommendations.
result SAFER outperforms state-of-the-art baselines in recommendation metrics and mortality rates.
Paper develops methods for evaluating mHealth interventions using historical data.
problem Evaluating the long-term effectiveness of mHealth interventions designed for near-term outcomes.
method Develops off-policy estimation techniques to infer long-term average outcomes from historical data.
result Provides estimators and confidence intervals for evaluating mHealth policies.
This paper presents the first deep reinforcement learning (DRL) framework to estimate the optimal Dynamic Treatment Regimes from observational medical data. This framework is more flexible and adaptive for high dimensional action and state spaces than existing reinforcement learning methods to model real-life complexit…
New test for binary treatment effects using kernel methods.
problem Testing distributional effects of binary treatments.
method Kernel-based doubly-robust test, avoiding permutations.
result Valid type-I error with computational efficiency.
XTNet estimates complex cross-treatment effects in multi-category, multi-valued settings.
problem Challenges in estimating causal effects for multi-category, multi-valued treatments.
method Dynamic Neural Masking for capturing treatment interactions without restrictive assumptions.
result XTNet consistently outperforms state-of-the-art baselines in multi-category, multi-valued treatment effect estimation.
Estimates heterogeneous treatment effects in panel data with a new method.
problem Estimating heterogeneous treatment effects in panel data with general treatment patterns.
method Partition observations into clusters with similar treatment effects using a regression tree, then estimate average treatment effects for each cluster.
result Our method achieves superior accuracy compared to alternative approaches.
Background. Real-world data show that approximately 50% of psoriasis patients treated with a biologic agent will discontinue the drug because of loss of efficacy. History of previous therapy with another biologic, female sex and obesity were identified as predictors of drug discontinuations, but their individual predic…
NICE model estimates causal effects for image treatments.
problem Challenges in causal effect estimation for multi-dimensional treatments.
method Proposes NICE model for image treatments, incorporating rich multidimensional information.
result NICE significantly outperforms existing models in estimating causal effects for image treatments.
ICA accurately estimates treatment effects even with confounders.
problem Estimating treatment effects in the presence of confounding variables.
method Uses Independent Component Analysis (ICA) to identify latent sources and estimate mixing coefficients.
result Linear ICA can consistently estimate multiple treatment effects, even with Gaussian confounders, and is more sample-efficient than Orthogonal Machine Learning (OML).
Method improves treatment effect estimation in randomized experiments.
problem Estimating distributional treatment effects in randomized experiments.
method Distributional regression framework with machine learning for variance reduction.
result The proposed method reduces variance of distributional treatment effect estimators.
The causal effect of a treatment can vary from person to person based on their individual characteristics and predispositions. Mining for patterns of individual-level effect differences, a problem known as heterogeneous treatment effect estimation, has many important applications, from precision medicine to recommender…
Novel method to quantify aleatoric uncertainty of treatment effects from observational data.
problem Understanding randomness in treatment effects for medical treatments.
method Partial identification and Neyman-orthogonality to quantify aleatoric uncertainty.
result Developed a novel orthogonal learner (AU-learner) for quantifying aleatoric uncertainty.
Develops a novel approach for estimating optimal DTRs with multicategory treatments and censored data.
problem Estimating optimal treatment regimes for chronic diseases with censored data.
method Angle-based multicategory classification algorithm for maximizing conditional survival function.
result The proposed method outperforms existing approaches in maximizing conditional survival function.
Develops methods for causal inference in longitudinal data.
problem Estimating Individual Treatment Effects (ITEs) in high-dimensional, time-varying data.
method Causal Dynamic Variational Autoencoder (CDVAE) and long-term counterfactual regression framework.
result CDVAE outperforms baselines and improves state-of-the-art models, approaching oracle performance.
GraphITE estimates individual effects of graph-structured treatments.
problem Estimating individual effects of complex treatment structures.
method Graph neural networks and Hilbert-Schmidt Independence Criterion regularization.
result GraphITE outperforms baselines in estimating treatment effects for large numbers of treatments.
Dynamic treatment effects estimated over time using covariate balancing.
problem Estimating treatment effects in panel data with dynamic treatments.
method Dynamic covariate balancing with potential local projections.
result Established inferential guarantees for the proposed method.
Selective imputation improves treatment effect estimation from missing data.
problem Missing data complicates treatment effect estimation, especially with treatment variables.
method Introduced mixed confounded missingness (MCM) and selective imputation.
result Selective imputation provides unbiased treatment effect estimates.
The paper compares methods for estimating heterogeneous treatment effects using multiple randomized trials.
problem Estimating heterogeneous treatment effects reliably and precisely with a single dataset is challenging.
method Non-parametric approaches for estimating heterogeneous treatment effects using data from multiple trials.
result Methods that directly allow for heterogeneity of the treatment effect across trials perform better than those that do not.