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arXiv research

A locally-built, LLM-digested index of recent arXiv papers in quant finance, geometry/topology, and statistical ML — keyword search served straight from SQLite on this machine.

168,786 papers · 148 categories

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6.4%12.8%19.3%25.7% · Jun 202519922001200920172026
48 results for latent profile analysis

Study identifies subphenotypes of pediatric sepsis to improve ML predictive performance.

problem Enhance machine learning predictive performance in pediatric sepsis.
method Latent profile analysis of clinical data to identify subphenotypes, followed by ML experiments.
result Improved predictive performance of ML models targeting specific subphenotypes of pediatric sepsis.

Modeling correlated mutations in cancer for personalized treatment.

problem Identifying mutations for personalized cancer therapy in heterogeneous profiles.
method Proposed correlated zero-inflated negative binomial process with mixed beta-Bernoulli and variational inference.
result Identified biologically relevant correlations between somatic mutations.

New method resolves causal heterogeneity by defining a resolution profile.

problem Causal subgroup analyses often oversimplify heterogeneity into a small number of groups.
method Introduces a resolution profile as a functional of the causal feature law, using Bayesian-bootstrap inference.
result Shows that the resolution profile is a continuous path with discontinuities at knots, providing integer-valued subgroup numbers.

Paper tackles cancer mutation data challenges by creating useful low-dimensional representations.

problem Challenges in analyzing and using cancer mutation data for classification and clustering.
method Flatsomatic: variational autoencoders (VAEs) to create latent representations of somatic profiles.
result VAE embeddings perform better than PCA for clustering and equally well for classification.

New method explains high-dimensional sphere data with latent factors.

problem Understanding intricate dependence structure in high-dimensional sphere data.
method Exploratory factor analysis of the projected normal distribution with a fast alternating expectation profile conditional maximization algorithm.
result Uniformly excellent results on various data types, including tweets, brain imaging, and cancer gene expression.

Sparse GFA identifies disease factors in FTD subgroups.

problem Heterogeneity in neurological disorders hinders understanding and treatment.
method Sparse Group Factor Analysis (GFA) with regularised horseshoe priors.
result Identified latent disease factors differentially expressed in FTD subgroups.

Efficiently matches random graphs with inhomogeneous edge probabilities.

problem Matching latent vertex correspondence between two correlated random graphs with inhomogeneous edge probabilities.
method Inspired by Ding et al. (2021), an efficient matching algorithm is developed with conditions on minimal average degree and minimal correlation.
result An efficient matching algorithm is obtained as long as the minimal average degree is at least Ω(log2n)Ω(\log^{2} n) and the minimal correlation is at least 1O(log2n)1 - O(\log^{-2} n).

New model generates realistic single-cell gene expression data.

problem Generating realistic single-cell gene expression profiles is challenging.
method scLDM, a latent diffusion model using Diffusion Transformers and linear interpolants.
result Superior performance in generating realistic single-cell gene expression data.

We extend multi-way, multivariate ANOVA-type analysis to cases where one covariate is the view, with features of each view coming from different, high-dimensional domains. The different views are assumed to be connected by having paired samples; this is a common setup in recent bioinformatics experiments, of which we a…

2009-12-16abs ↗pdf ↗

XSP profiles ML models across hardware and software stacks.

problem Challenges in profiling ML model performance across different layers of the stack.
method XSP uses distributed tracing to aggregate data from various sources and introduces a leveled, iterative measurement approach.
result XSP provides insights into ML model execution not easily discernible otherwise.

StepMix estimates mixture models with covariates for social science applications.

problem Estimating latent classes with covariates in social science models.
method Pseudo-likelihood estimation using one-, two-, and three-step approaches.
result Unified framework for expectation-maximization subroutines.

We introduce a novel latent grouping model for predicting the relevance of a new document to a user. The model assumes a latent group structure for both users and documents. We compared the model against a state-of-the-art method, the User Rating Profile model, where only users have a latent group structure. We estimat…

2012-07-04abs ↗pdf ↗

The paper develops methods to infer membership probabilities and rank network nodes using the DCMM model.

problem Understanding the latent structure of network data, especially in mixed-membership models.
method Degree-Corrected Mixed Membership (DCMM) model, novel finite-sample expansion, asymptotic distributions, confidence intervals, multiplier bootstrap method.
result Valid inference on membership probabilities and node rankings, quantifying uncertainty.

A new framework for adaptive behavior using reusable value profiles.

problem Adaptive behavior in changing environments requires switching among value-control regimes, but maintaining separate parameters for each situation is impractical.
method Introduces value profiles: reusable bundles of parameters assigned to hidden states, allowing for state-conditional strategy recruitment without independent parameters for each context.
result Profile-based models outperform simpler alternatives in probabilistic reversal learning, suggesting belief-dependent control of adaptive behavior.

Flatsomatic compresses cancer mutation data with VAEs, maintaining predictive power.

problem Compressing somatic mutation profiles in cancer while preserving predictive power.
method Flatsomatic uses a Variational Auto Encoder (VAE) with MLP architecture, optimizing evidence lower bound and beta-VAE for latent space regularization.
result Flatsomatic embeddings maintain predictive power of original data, reducing dimensionality from 8,298 to 64.

Unsupervised method selects genes for tumor subtype discovery.

problem High-dimensional tumor gene expression data with noisy variables and heterogeneity.
method Autoencoders for latent space learning, Multiple Kernel Learning for feature selection, clustering.
result Lower redundancy and better clustering performance compared to benchmarks.

A novel criterion selects optimal distance metrics for cell profile analysis.

problem Determining the most accurate distance metric for high-dimensional cell profiles.
method Generalized proposition and corollaries to evaluate and select distance metrics.
result Wasserstein and cosine similarity metrics are optimal for general cases.

Generative profiling improves real-time task timing for varied resource contexts.

problem Inaccurate task timing analysis for complex hardware architectures.
method Nonparametric, conditional multi-marginal Schrödinger Bridge (MSB) formulation for synthesizing context-dependent timing profiles.
result Maximum likelihood accurate execution profiles for unseen resource contexts.

Generative model tailors anticancer drugs based on transcriptomic data.

problem Designing effective anticancer drugs considering genetic profiles.
method RL framework using pretrained VAEs to generate compounds conditioned on transcriptomic data.
result Generative model produces molecules with high predicted inhibitory effects.

Machine learning detects subtle glucose changes for early diabetes diagnosis.

problem Challenging early-stage diabetes diagnosis due to subtle glucose changes.
method Applied machine learning to synthetic glucose profiles generated by a biophysical model.
result High accuracy (above 85%) in detecting insulin resistance using various neural networks.

The possibility of using player engagement predictions to profile high spending video game users is explored. In particular, individual-player survival curves in terms of days after first login, game level reached and accumulated playtime are used to classify players into different groups. Lifetime value predictions fo…

2019-07-09abs ↗pdf ↗

Extends multidimensional scaling to analyze three-way asymmetric proximities.

problem Analyzing asymmetric and three-way proximities in a Euclidean space.
method Unified h-plot methodology for three-way asymmetric proximities, including symmetric and conditional frameworks.
result Identification of archetypal profiles and clustering structures.

Estimates statistical power for cluster analysis in biomedical research.

problem Lack of established methods to compute a priori statistical power for cluster analysis.
method Simulation studies varying subgroup size, number, separation, and covariance structure.
result Sufficient statistical power achieved with small samples (N=20-30) for large effect sizes.

ProtoX-AD: A self-explainable time series anomaly detection framework

problem Lack of explainability in self-supervised time series anomaly detection
method Learning transformation-aware latent representations and interpretable prototypes
result Achieves detection performance comparable to black-box methods while offering more consistent and semantically meaningful explanations

We present a novel, log-radius profile representation for convex curves and define a new operation for combining the shape features of curves. Unlike the standard, angle profile-based methods, this operation accurately combines the shape features in a visually intuitive manner. This method have implications in shape an…

2015-06-24abs ↗pdf ↗

Expanding on techniques of concentration of measure, we develop a quantitative framework for modeling liquidity risk using convex risk measures. The fundamental objects of study are curves of the form (ρ(λX))λ0(ρ(λX))_{λ\ge 0}, where ρρ is a convex risk measure and XX a random variable, and we call such a curve a \emph{liqu…

2015-10-23abs ↗pdf ↗

Analyzes Gerstner's trochoidal waves and their geometric properties.

problem Understanding the geometry and kinematics of trochoidal waves.
method Derives velocity and arc length conditions for cycloidal, curtate, and prolate trochoids using Galilean transformations.
result Conditions for arc lengths of prolate and curtate trochoids to coincide over a wave cycle.

The linking genotype to phenotype is the fundamental aim of modern genetics. We focus on study of links between gene expression data and phenotype data through integrative analysis. We propose three approaches. 1) The inherent complexity of phenotypes makes high-throughput phenotype profiling a very difficult and labor…

2015-06-29abs ↗pdf ↗

Profile graphical models represent multivariate dependence under varying risk factors.

problem Capturing varying conditional independence structures across different levels of a risk factor.
method Introducing a novel class of graphical models (profile graphical models) that represent multivariate dependence under varying risk factors, and developing a Bayesian approach for learning shared sparsity structures.
result Demonstrated enhanced ability to capture subject-specific differences in protein network data from acute myeloid leukemia.

Study ridge regression for non-identically distributed data with varying variances.

problem Investigate high-dimensional regression with non-identical data variance.
method Propose a random effect model and use tools from random matrix theory.
result Highlight the double descent phenomenon in high-dimensional regression for certain variance profiles.