Establishing criteria for top cell inertness in complexes.
arXiv research
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Study inert and ambiguous classes in modular group using combinatorial methods.
For a closed surface with , we show that the fixed subgroup of a family of endomorphisms of has $\rk \fix\mathcal B\leq \rk π_1(S)$. In particular, if contains a non-epimorphic endomorphism, then $\rk \fix\mathcal B\leq \frac{1}{2} \rk π_1(S)$. We also show that geometric …
We study the effect of investor inertia on stock price fluctuations with a market microstructure model comprising many small investors who are inactive most of the time. It turns out that semi-Markov processes are tailor made for modelling inert investors. With a suitable scaling, we show that when the price is driven …
We propose a new deep learning approach for medical imaging that copes with the problem of a small training set, the main bottleneck of deep learning, and apply it for classification of healthy and cancer cells acquired by quantitative phase imaging. The proposed method, called transferring of pre-trained generative ad…
We show that there are two homotopy types of PD_3-complexes with fundamental group S_3*_{Z/2Z}S_3, and give explicit constructions for each, which differ only in the attachment of the top cell.
New insights into the top-K sparse softmax gating function for deep learning.
New metric scores perturbations across populations, not cells, improving model comparison.
Developing neural network image classification models often requires significant architecture engineering. In this paper, we study a method to learn the model architectures directly on the dataset of interest. As this approach is expensive when the dataset is large, we propose to search for an architectural building bl…
We construct periodic families of Poincare complexes, partially solving a question of Hodgson that was posed in the proceedings of the 1982 Northwestern homotopy theory conference. We also construct infinite families of Poincare complexes whose top cell falls off after one suspension but which fail to embed in a sphere…
The paper proves properties of manifolds under certain conditions.
Dr.S recommends cancer drugs based on genomic data.
In \cite{Boed}, C.-F. Bödigheimer constructed a finite cell-complex $\mf{Par}_{g,n,m}$ and a bijective map $\cH: \mf{Dip}_{g,n,m} \to \mf{Par}_{g,n,m}$ (the Hilbert-uniformization) from the moduli space of dipole functions on Riemann surfaces with directions and punctures to $\mf{Par}_{g,n,m}$. In \cite{Boed} a…
Study of generalized double Bruhat cells and their integrations.
Study identifies biomarkers for lung cancer in female non-smokers.
Donor-aware scRNA-seq benchmarks improve classification accuracy in inflammatory bowel disease.
This paper proposes a new hashing-based KNN technique for faster nearest neighbor selection.
Triangulations of R^n have at least tensor rank of determinant simplices.
Consider a finite connected graph possibly with multiple edges and loops. In discrete geometric analysis, Kotani and Sunada constructed the crystal associated to the graph as a standard realization of the maximal abelian covering of the graph. As an application of what the author showed in an earlier paper with Seshadr…
Analysis of histopathology slides is a critical step for many diagnoses, and in particular in oncology where it defines the gold standard. In the case of digital histopathological analysis, highly trained pathologists must review vast whole-slide-images of extreme digital resolution ( pixels) across multiple…
Kernel testing compares cell states in single-cell data.
This study reviews and evaluates clustering methods for single-cell RNA-seq data.
Cell detection and cell type classification from biomedical images play an important role for high-throughput imaging and various clinical application. While classification of single cell sample can be performed with standard computer vision and machine learning methods, analysis of multi-label samples (region containi…
Forest Fire Clustering discovers cell types from single-cell data.
Proposes CCCVAE for better single-cell clustering with cell-cell communication.
Matching cells over time has long been the most difficult step in cell tracking. In this paper, we approach this problem by recasting it as a classification problem. We construct a feature set for each cell, and compute a feature difference vector between a cell in the current frame and a cell in a previous frame. Then…
Improved GPLVM model for single-cell RNA-seq data.
This article is one of three highly influential articles on the topology of manifolds written by Robert D. Edwards in the 1970's but never published. Organizers of the Workshops in Geometric Topology (http://www.uwm.edu/~craigg/workshopgtt.htm) with the support of the National Science Foundation have facilitated the pr…
We prove that if is a CW-complex, then the homotopy type of the skeletal filtration of does not depend on the cell decomposition of up to wedge products with -disks , when the later are given their natural CW-decomposition with unique cells of order 0, and ; a result resembling J.H.C. Whi…
The study identifies all possible vector field structures on specific 2D shapes.
New model identifies cell-specific genes for cancer prognosis.
MarkerMap selects key genes for cell type analysis in single-cell RNA-seq.
Proposes CXNs for neural network computations on cell complexes.
Cataloging the neuronal cell types that comprise circuitry of individual brain regions is a major goal of modern neuroscience and the BRAIN initiative. Single-cell RNA sequencing can now be used to measure the gene expression profiles of individual neurons and to categorize neurons based on their gene expression profil…
The process of morphogenesis, which can be defined as an evolution of the form of an organism, is one of the most intriguing mysteries in the life sciences. It is clear, that gene expression patterns cannot explain the development of the precise geometry of an organism and its parts in space. Here, we suggest a set of …
Hippocampal dentate granule cells are among the few neuronal cell types generated throughout adult life in mammals. In the normal brain, new granule cells are generated from progenitors in the subgranular zone and integrate in a typical fashion. During the development of epilepsy, granule cell integration is profoundly…
NESS improves neighbor embedding for smooth cell-state transitions in single-cell data.
New model clusters cells and individuals, revealing genetic influences on cell types.
Cell-based NAS search spaces are redundant and lack novelty.
New method classifies reticulocytes from red blood cells without labels.
For a finite family of 3-dimensional almost contact metric manifolds with closed the structure form is described a construction of an almost contact metric manifold, where the members of the family are building blocks - cells. Obtained manifold share many properties of cells. One of the more important are nullity c…
HSSE framework embeds single-cell RNA-seq data at multiple scales.
Researchers infer gene activity in dividing cells, accounting for protein inheritance and division history.
SimCD simultaneously clusters cells and identifies differential gene expression in scRNA-seq data.
Understanding cell identity is an important task in many biomedical areas. Expression patterns of specific marker genes have been used to characterize some limited cell types, but exclusive markers are not available for many cell types. A second approach is to use machine learning to discriminate cell types based on th…
Two simple homotopy equivalent 2-complexes K2 and L2 are related by an algebraic criterion of their corresponding presentations as stated in [HoMeSier]. Frank Quinn set it into a topological context (see [Qu1]) and call these 2-complexes related by an s-move. Using elementary 3-expansions, K2 extends to 3-cells in K3 r…
The study compares different scRNA sequencing methods using a high-dimensional dataset.
We construct a small regular cellular decomposition of the Fulton MacPherson operad that is compatible with the operad composition. The cells are indexed by trees with edges of two colors and vertices labelled by cells of the cacti operad. We compute the generating functions counting the cells, that are algebrai…