Random forest models predict CLABSI risk in hospital admissions, with static models performing similarly to dynamic ones.
problem Predicting CLABSI risk in hospital admissions using EHR data with competing risks.
method Comparison of static and dynamic random forest models for binary, multinomial, survival, and competing risks outcomes.
result Static and dynamic random forest models perform similarly in predicting CLABSI risk, with multinomial models having the lowest computation times.
New method for discrete-time survival analysis with competing risks.
problem Discrete failure time data in survival analysis.
method Proposes a new estimation procedure for discrete-time survival analysis with competing events.
result Offers advantages over existing procedures and integrates regularized regression methods.
auton-survival simplifies survival analysis for healthcare data.
problem Handling censored time-to-event data in healthcare.
method Open-source package for survival regression, adjustment, counterfactual estimation, phenotyping, and treatment effects.
result Demonstrates auton-survival's ability to support complex health and epidemiological questions.
Tree-based model averaging improves CATE estimation from diverse sites.
problem Limited sample size and privacy concerns prevent accurate personalized treatment effect estimation.
method Tree-based model averaging approach to estimate CATEs from multiple heterogeneous sites.
result Improved accuracy in estimating conditional average treatment effects (CATEs) across sites.
Study evaluates federated learning for ICU survival prediction using eICU data.
problem Training models on multi-center healthcare data without data sharing.
method Federated Averaging, varying hyper-parameters, analyzing client sizes.
result Optimal performance with a large number of local training epochs and reduced communication costs.
Study identifies risk factors for subsequent suicide attempts in youth.
problem Uncertainty in suicide attempt identification from medical claims data.
method Integrative Cox cure model with regularization for survival analysis with uncertain events.
result Identifies risk factors for subsequent suicide attempts and distinguishes susceptibility from timing.
X-CAL improves survival model calibration without sacrificing predictive power.
problem Improving the calibration of survival models to better match observed data.
method Explicit calibration (X-CAL) turns distributional calibration into a differentiable objective for survival modeling.
result X-CAL improves calibration metrics without significantly reducing predictive performance.
Neural model predicts survival outcomes and reveals feature relationships.
problem Predicting time-to-event outcomes and understanding feature relationships in clinical data.
method Survival and topic modeling combined in a neural network framework.
result Neural survival-supervised topic models achieve competitive accuracy with interpretability.
Paper models treatment effects by clustering patients with distinct survival characteristics.
problem Estimating treatment efficacy in clinical settings with censored outcomes.
method Latent variable approach to model heterogeneous treatment effects.
result The latent structure can mediate base survival rates and reveal actionable phenotypes.
Febrile neutropenia (FN) has been associated with high mortality, especially among adults with cancer. Understanding the patient and provider level heterogeneity in FN hospital admissions has potential to inform personalized interventions focused on increasing survival of individuals with FN. We leverage machine learni…
Study finds non-adherence to schizophrenia meds leads to earlier adverse events.
problem Impact of medication non-adherence on adverse outcomes in schizophrenia patients.
method Survival analysis, causal inference methods (T-learner, S-learner, nearest neighbor matching), different amounts of longitudinal information.
result Non-adherence to schizophrenia meds advances adverse events by 1 to 4 months.
Paper addresses data heterogeneity in federated learning for CoxPH models in healthcare.
problem Data heterogeneity in federated learning of CoxPH models for healthcare.
method Feature-based clustering and event-based reporting strategy.
result Enhanced model accuracy and performance in federated survival analysis.
Quantum neural networks improve causal inference in biomedical studies, especially for small samples.
problem Addressing selection bias in comparing surgical techniques using observational data.
method Developed QNN-based propensity score models focusing on four key covariates (Age, Sex, Stage, BMI). Employed a linear ZFeatureMap for data encoding, SummedPaulis for predictions, and CMA-ES for optimization. Integrated noise modeling to enhance predictive stability.
result QNNs, particularly with noise-aware strategies, outperformed classical models in small samples, achieving AUC up to 0.750 for n=100.
Hospital Readmissions within 30 days after discharge following Coronary Artery Bypass Graft (CABG) Surgery are substantial contributors to healthcare costs. Many predictive models were developed to identify risk factors for readmissions. However, majority of the existing models use statistical analysis techniques with …
FedRD improves risk difference estimation in federated learning for clinical outcomes.
problem Privacy-preserving model co-training in medical research is hindered by server-dependent architectures and focus on relative effect measures.
method FedRD is a server-independent, communication-efficient framework for federated risk difference estimation in distributed survival data.
result FedRD provides valid confidence intervals and hypothesis testing, and is asymptotically equivalent to pooled individual-level analysis.
Over the past decades, both critical care and cancer care have improved substantially. Due to increased cancer-specific survival, we hypothesized that both the number of cancer patients admitted to the ICU and overall survival have increased since the millennium change. MIMIC-III, a freely accessible critical care data…
Bayesian models forecast COVID-19 hospitalizations at single sites.
problem Forecasting daily COVID-19 hospitalizations at a single hospital.
method Hierarchical Bayesian models with generalized Poisson likelihood and autoregressive/Gaussian process latent processes.
result Demonstrated superior performance compared to baselines in public datasets.
Study predicts future hospitalizations to manage COVID-19 patient surge.
problem Managing hospitalization needs during COVID-19 pandemic.
method Used 4 recurrent neural networks to predict hospitalization changes.
result Sequence to sequence model with attention achieved high accuracy and AUC.
Early results in using convolutional neural networks (CNNs) on x-rays to diagnose disease have been promising, but it has not yet been shown that models trained on x-rays from one hospital or one group of hospitals will work equally well at different hospitals. Before these tools are used for computer-aided diagnosis i…
Natural language processing improves COVID-19 hospitalization identification.
problem Identifying patients hospitalized due to COVID-19 among those with positive SARS-CoV-2 tests.
method Used natural language processing on provider notes and structured EHR data elements to create classification algorithms.
result Classification algorithms using provider notes outperformed those using only structured EHR data elements, with AUROC of 0.894 compared to 0.841.
Adversarial method improves pneumonia classifier's performance across hospitals.
problem Robust classification of pneumonia from chest radiographs across different hospitals.
method Adversarial optimization to learn models invariant to confounders.
result Improved out-of-hospital generalization performance compared to baselines.
Deep neural network predicts diabetic readmission with high accuracy.
problem Predicting 30-day readmission for diabetic patients.
method Categorical embeddings and deep neural network.
result 95.2% accuracy and 97.4% AUROC on diabetic readmission data.
CPAS uses machine learning to plan hospital resources for COVID-19.
problem Forecasting hospital resource demands during the COVID-19 pandemic.
method Combining machine learning algorithms with diverse data sources.
result CPAS successfully managed hospital resource planning in the UK.
Acute Kidney Injury (AKI), a sudden decline in kidney function, is associated with increased mortality, morbidity, length of stay, and hospital cost. Since AKI is sometimes preventable, there is great interest in prediction. Most existing studies consider all patients and therefore restrict to features available in the…
The paper uses SHAP for interpreting machine learning models in hospital data.
problem Interpreting machine learning models in healthcare.
method SHAP for feature importance and feature packing techniques.
result SHAP provides better interpretability of machine learning models in healthcare.
FUALA improves Federated Learning for EHR data, enhancing model uncertainty.
problem Applying ML to EHR data while maintaining privacy and accuracy.
method FUALA embeds uncertainty in federated learning, using ensembling and averaging.
result FUALA outperforms FedAvg on out-of-distribution data in EHR model predictions.
Algorithm detects surgical site infections from hospital data.
problem Reduces incidence of surgical site infections in hospitals.
method Machine learning algorithms trained on hospital data.
result Identifies all SSIs with minimal false positives.
Paper shows federated learning can train models on private data.
problem Training predictive models on private hospital data.
method Distributed training in federated learning framework.
result Federated learning achieves comparable performance to traditional methods.
Develops a method for causal inference in recurrent event data with terminal failure.
problem Causal inference in recurrent event data with a terminal event.
method Multiply robust estimation framework for causal inference.
result Proposes an estimator for the expected number of recurrent events and failure survival function.
Machine learning improves early detection of patient deterioration in Brazilian hospitals.
problem Challenges in recognizing clinical deterioration in hospital settings.
method Application of machine learning to analyze EHR data from multiple hospitals.
result Machine learning models outperformed traditional protocols by 25 percentage points in AUC.
Deep network clusters hospital patients' vital signs.
problem Sparse and irregularly collected vital sign data.
method Deep interpolation network for latent representation extraction.
result Extracted 7 distinct clusters from vital sign data.
SurvMixClust clusters survival data and predicts individual survival curves.
problem Integrating clustering into survival analysis for precision medicine.
method SurvMixClust learns latent representations for clustering and predicts survival functions using a mixture of non-parametric experts.
result SurvMixClust creates balanced clusters with distinct survival curves, outperforming clustering baselines and competing with non-clustering models in predictive accuracy.
Trans-GLMC tackles source heterogeneity in transfer learning for structured clusters.
problem Source heterogeneity makes it hard to use multiple related auxiliary sources effectively.
method Trans-GLMC constructs clusters of sources, then combines global fusion, within-cluster refinement, and target debiasing.
result Improves facility-specific prediction and identifies interpretable communities of hospitals with mutual transferability.
The paper predicts survival functions using random survival trees and concordance maximization.
problem Predicting conditional survival functions in right-censored data.
method The approach combines regression strategies with random survival trees and maximizes concordance.
result The proposed weighted predictor outperforms the usual survival cobra in terms of concordance.
Survival kernets scale deep kernel survival analysis to large datasets with interpretability and theoretical guarantees.
problem Scalable and interpretable deep kernel survival analysis for large datasets.
method Survival kernets use kernel netting for training set compression and XGBoost for warm-starting neural architecture search.
result Survival kernets achieve optimal time-dependent concordance index on various survival analysis datasets.
Survival MDN uses invertible functions to speed up survival analysis models.
problem Training neural ODEs for survival analysis is computationally expensive.
method Survival MDN applies an invertible positive function to MDN outputs.
result Survival MDN outperforms or matches other models on concordance, Brier score, and log-likelihood.
RSM provides insights into deep survival models' decision-making.
problem Ensuring trust in deep survival models' predictions for healthcare applications.
method Reverse survival model (RSM) framework that explains deep survival models' decisions.
result RSM extracts relevant features for deep survival models' predictions.
Neural network learns kernel functions for survival analysis and prediction intervals.
problem Predicting survival times for individuals based on similar training subjects.
method Develops a neural network framework to learn kernel functions for kernel survival analysis and uses these to construct valid prediction intervals.
result Neural network survival estimators are competitive with existing methods and provide valid prediction intervals.
Hospital readmissions have become one of the key measures of healthcare quality. Preventable readmissions have been identified as one of the primary targets for reducing costs and improving healthcare delivery. However, most data driven studies for understanding readmissions have produced black box classification and p…
Reduces survival analysis to common regression tasks.
problem Applying standard machine learning tools to survival analysis.
method Various reduction techniques to simplify survival analysis.
result Benchmark analysis shows improved predictive performance.
A new method clusters survival data using deep variational models.
problem Clustering survival data, a challenging task.
method Semi-supervised probabilistic approach with deep generative model.
result The method outperforms previous models in clustering and predicting survival times.
The paper compares Bayesian trees, Cox models, and random forests for breast cancer survival data.
problem Modeling survival data with nonlinear and additive effects.
method Bayesian Additive Regression Trees, Cox proportional hazards, and Random Survival Forests.
result Bayesian trees outperform other models in terms of bias and prediction accuracy.
We investigate the effect of the proportional hazards assumption on prognostic and predictive models of the survival time of patients suffering from amyotrophic lateral sclerosis (ALS). We theoretically compare the underlying model formulations of several variants of survival forests and implementations thereof, includ…
Optimal Survival Trees improve accuracy in medical data analysis.
problem Analyzing censored outcomes in medical data.
method Mixed-integer optimization and local search techniques.
result Improves accuracy in large datasets compared to existing methods.
New scalable method balances hospital profit status and heart attack outcomes.
problem Balancing covariate distributions and minimizing weight dispersion in large datasets.
method Combines kernel basis expansion and convex optimization for efficient and flexible weighting.
result For-profit hospitals use interventional cardiology similarly to other hospitals but have higher mortality and readmission rates.
RSF models censored functional data for better survival analysis.
problem Modeling survival trajectories with censored data.
method Random Survival Forest for Censored Functional Data (RSF).
result Good performance in predicting survival variables.
Study predicts 10-year survival rates for breast cancer patients.
problem Predicting long-term survival of breast cancer patients.
method Machine learning approaches to assess survival rates.
result Improved accuracy in predicting 10-year survival.
Improves survival analysis across multiple domains with machine learning.
problem Adapting survival analysis to new or rare illness types with limited labeled data.
method Introduces a new survival metric and discrepancy measure for censored data, enabling domain adaptation.
result Superb performance on target domains, better treatment recommendations, and interpretable weight matrix.