A novel continual prediction model outperforms traditional one-time models in predicting AKI.
problem Optimally predicting AKI before it develops during a hospital stay.
method A novel continual prediction model that predicts AKI every time a patient's AKI-relevant variable changes in the EHR.
result The continual prediction model outperformed traditional one-time models, achieving a higher AUC of 0.724 compared to 0.653.
Study uses ML to predict cancer patient mortality from FN onset.
problem Predicting mortality in cancer patients with FN to improve survival.
method Multi-domain machine learning models using HCUP data.
result Clinical diagnoses have highest predictive power for FN mortality.
Inpatient care is a large share of total health care spending, making analysis of inpatient utilization patterns an important part of understanding what drives health care spending growth. Common features of inpatient utilization measures include zero inflation, over-dispersion, and skewness, all of which complicate st…
Federated learning clusters EMRs to improve mortality and stay predictions.
problem Decentralized, non-IID EMRs complicate centralized machine learning algorithms.
method Introduced CBFL algorithm that clusters EMRs into communities for federated learning.
result CBFL outperforms baseline FL algorithm in ROC AUC, PR AUC, and communication cost.
Study predicts antimicrobial resistance in ICU patients quickly.
problem Delayed AMR testing in ICU leads to suboptimal treatment.
method Developed predictive models using clinical and microbiological data.
result Machine learning models predict AMR with higher accuracy than naive model.
Clinical notes improve ICU patient condition prediction.
problem Predicting ICU patient outcomes and resource planning.
method Joint modeling of time series data and clinical notes.
result Significant improvement in mortality prediction, decompensation modeling, and length of stay forecasting.
Acute Kidney Injury (AKI), a sudden decline in kidney function, is associated with increased mortality, morbidity, length of stay, and hospital cost. Since AKI is sometimes preventable, there is great interest in prediction. Most existing studies consider all patients and therefore restrict to features available in the…
New model predicts ICU patients' stay duration efficiently.
problem Efficient ICU bed allocation under resource constraints.
method Temporal Pointwise Convolution (TPC) model combining temporal and pointwise convolutions.
result Significant performance improvements over LSTM and Transformer models.
Selective prediction-set models improve predictive reliability and uncertainty quantification.
problem Inaccurate and unreliable predictions from black-box models, especially for unfamiliar data.
method Training selective prediction-set models using uncertainty-aware loss minimization, and calculating well-calibrated prediction sets.
result Selective prediction-set models outperform existing approaches in predicting in-hospital mortality and length-of-stay for ICU patients.
New model predicts ICU patient stays more accurately.
problem Efficient ICU bed allocation under resource constraints.
method Temporal Pointwise Convolutional Networks (TPC) combining temporal and pointwise convolutions.
result Significant performance improvements over LSTM and Transformer models.
Hospital readmissions have become one of the key measures of healthcare quality. Preventable readmissions have been identified as one of the primary targets for reducing costs and improving healthcare delivery. However, most data driven studies for understanding readmissions have produced black box classification and p…
Traditional methods for assessing illness severity and predicting in-hospital mortality among critically ill patients require time-consuming, error-prone calculations using static variable thresholds. These methods do not capitalize on the emerging availability of streaming electronic health record data or capture time…
Bayesian model forecasts hospital resource use during pandemic.
problem Modeling constrained hospital resources during pandemic.
method Approximate Bayesian Computation for an ACED-HMM.
result Mechanistic approach provides competitive probabilistic forecasts.
This study shows unstructured clinical notes can improve mortality prediction.
problem Lack of effective use of unstructured clinical notes in mortality prediction.
method Used a hierarchical architecture with convolutional and recurrent layers to predict in-hospital mortality from unprocessed clinical notes.
result Achieved higher metrics in mortality prediction compared to structured data approaches.
Machine learning for healthcare often trains models on de-identified datasets with randomly-shifted calendar dates, ignoring the fact that data were generated under hospital operation practices that change over time. These changing practices induce definitive changes in observed data which confound evaluations which do…
Study compares federated and centralized learning for patient data privacy.
problem Ensuring privacy in machine learning models trained on electronic health records.
method Examined private and non-private federated learning for clinical prediction tasks.
result Differentially private stochastic gradient descent is effective in centralized learning but challenging in federated learning.
New method for discrete-time survival analysis with competing risks.
problem Discrete failure time data in survival analysis.
method Proposes a new estimation procedure for discrete-time survival analysis with competing events.
result Offers advantages over existing procedures and integrates regularized regression methods.
Study proposes managing COVID-19 without economy shutdowns.
problem Avoiding lockdowns while maintaining healthcare system capacity.
method Detailed heterogeneous epidemiological model, calibrated to data.
result Countries can avoid lockdowns if ICU beds per million > 100.
Study evaluates federated learning for ICU survival prediction using eICU data.
problem Training models on multi-center healthcare data without data sharing.
method Federated Averaging, varying hyper-parameters, analyzing client sizes.
result Optimal performance with a large number of local training epochs and reduced communication costs.
A new model improves homogeneity in burn patient reimbursement.
problem Incomplete homogeneity checks for burn patients using LOS as a proxy.
method Cost-sensitive decision tree model considering patient-level cost and severity of burn.
result Identified groups with increased homogeneity compared to current HRG groups.
While the volume of electronic health records (EHR) data continues to grow, it remains rare for hospital systems to capture dense physiological data streams, even in the data-rich intensive care unit setting. Instead, typical EHR records consist of sparse and irregularly observed multivariate time series, which are wel…
Robust policies improve ICU transfer outcomes by predicting patient deterioration.
problem Higher mortality rates for unplanned ICU transfers.
method Markov Decision Process model to predict patient severity and optimize transfer policies.
result Robust policies are more aggressive in transferring patients than nominal policies, improving overall patient care.
Deep neural networks have shown promising results for various clinical prediction tasks such as diagnosis, mortality prediction, predicting duration of stay in hospital, etc. However, training deep networks -- such as those based on Recurrent Neural Networks (RNNs) -- requires large labeled data, high computational res…
Bayesian models forecast COVID-19 hospitalizations at single sites.
problem Forecasting daily COVID-19 hospitalizations at a single hospital.
method Hierarchical Bayesian models with generalized Poisson likelihood and autoregressive/Gaussian process latent processes.
result Demonstrated superior performance compared to baselines in public datasets.
Study predicts future hospitalizations to manage COVID-19 patient surge.
problem Managing hospitalization needs during COVID-19 pandemic.
method Used 4 recurrent neural networks to predict hospitalization changes.
result Sequence to sequence model with attention achieved high accuracy and AUC.
Study evaluates approaches to improve worst-case model performance across patient subpopulations.
problem Improving model accuracy for specific patient subpopulations.
method Comparison of distributionally robust optimization (DRO) and standard learning procedures.
result Standard learning procedures generally outperform DRO approaches for improving model performance across subpopulations.
Early hospital mortality prediction is critical as intensivists strive to make efficient medical decisions about the severely ill patients staying in intensive care units. As a result, various methods have been developed to address this problem based on clinical records. However, some of the laboratory test results are…
Early results in using convolutional neural networks (CNNs) on x-rays to diagnose disease have been promising, but it has not yet been shown that models trained on x-rays from one hospital or one group of hospitals will work equally well at different hospitals. Before these tools are used for computer-aided diagnosis i…
Natural language processing improves COVID-19 hospitalization identification.
problem Identifying patients hospitalized due to COVID-19 among those with positive SARS-CoV-2 tests.
method Used natural language processing on provider notes and structured EHR data elements to create classification algorithms.
result Classification algorithms using provider notes outperformed those using only structured EHR data elements, with AUROC of 0.894 compared to 0.841.
Adversarial method improves pneumonia classifier's performance across hospitals.
problem Robust classification of pneumonia from chest radiographs across different hospitals.
method Adversarial optimization to learn models invariant to confounders.
result Improved out-of-hospital generalization performance compared to baselines.
Deep neural network predicts diabetic readmission with high accuracy.
problem Predicting 30-day readmission for diabetic patients.
method Categorical embeddings and deep neural network.
result 95.2% accuracy and 97.4% AUROC on diabetic readmission data.
CPAS uses machine learning to plan hospital resources for COVID-19.
problem Forecasting hospital resource demands during the COVID-19 pandemic.
method Combining machine learning algorithms with diverse data sources.
result CPAS successfully managed hospital resource planning in the UK.
Proposes proactive bed requests to reduce ED boarding and patient wait times.
problem Reduces ED boarding and patient wait times by proactively requesting inpatient beds.
method Formulates as a Markov decision process, uses predictions of admission probability and time to disposition to guide bed requests.
result Proactive aggregate bed requests can reduce boarding times by 30-70% and length of stay by 6-15%.
The paper uses SHAP for interpreting machine learning models in hospital data.
problem Interpreting machine learning models in healthcare.
method SHAP for feature importance and feature packing techniques.
result SHAP provides better interpretability of machine learning models in healthcare.
FUALA improves Federated Learning for EHR data, enhancing model uncertainty.
problem Applying ML to EHR data while maintaining privacy and accuracy.
method FUALA embeds uncertainty in federated learning, using ensembling and averaging.
result FUALA outperforms FedAvg on out-of-distribution data in EHR model predictions.
Study describes severe dengue ICU patients in Brazil, 2012-2024.
problem Characterize severe dengue ICU patients and identify risk factors.
method Prospective study, descriptive statistics, logistic regression, machine learning.
result Advanced age, comorbidities, leukocytes, and platelets are significant risk factors for complications.
Research shows a significant increase in stay lengths for digital nomads in the U.S. during and after the pandemic.
problem Shifts in stay lengths for digital nomads during and after the pandemic.
method Analysis of Airbnb reservations data from 2019-2024, using statistical models to quantify changes.
result Mean stay lengths increased from 3.68 to 4.36 nights, stabilizing near 4.07 after 2021, indicating a 10% increase from pre-pandemic levels.
Algorithm detects surgical site infections from hospital data.
problem Reduces incidence of surgical site infections in hospitals.
method Machine learning algorithms trained on hospital data.
result Identifies all SSIs with minimal false positives.
Categorical Co-Frequency Analysis clusters diagnoses to predict hospital readmissions.
problem Predicting patients' risk of 30-day hospital readmission.
method Categorical Co-Frequency Analysis (CoFA) measures diagnosis similarity using random forests.
result Identified three groups of diagnoses with varying readmission risk.
Paper shows federated learning can train models on private data.
problem Training predictive models on private hospital data.
method Distributed training in federated learning framework.
result Federated learning achieves comparable performance to traditional methods.
Machine learning improves early detection of patient deterioration in Brazilian hospitals.
problem Challenges in recognizing clinical deterioration in hospital settings.
method Application of machine learning to analyze EHR data from multiple hospitals.
result Machine learning models outperformed traditional protocols by 25 percentage points in AUC.
Deep network clusters hospital patients' vital signs.
problem Sparse and irregularly collected vital sign data.
method Deep interpolation network for latent representation extraction.
result Extracted 7 distinct clusters from vital sign data.
Trans-GLMC tackles source heterogeneity in transfer learning for structured clusters.
problem Source heterogeneity makes it hard to use multiple related auxiliary sources effectively.
method Trans-GLMC constructs clusters of sources, then combines global fusion, within-cluster refinement, and target debiasing.
result Improves facility-specific prediction and identifies interpretable communities of hospitals with mutual transferability.
New scalable method balances hospital profit status and heart attack outcomes.
problem Balancing covariate distributions and minimizing weight dispersion in large datasets.
method Combines kernel basis expansion and convex optimization for efficient and flexible weighting.
result For-profit hospitals use interventional cardiology similarly to other hospitals but have higher mortality and readmission rates.
A large volume of research has considered the creation of predictive models for clinical data; however, much existing literature reports results using only a single source of data. In this work, we evaluate the performance of models trained on the publicly-available eICU Collaborative Research Database. We show that cr…
X-CAL improves survival model calibration without sacrificing predictive power.
problem Improving the calibration of survival models to better match observed data.
method Explicit calibration (X-CAL) turns distributional calibration into a differentiable objective for survival modeling.
result X-CAL improves calibration metrics without significantly reducing predictive performance.
The paper tackles distribution-free prediction intervals for multi-source data.
problem Challenges in achieving valid inferences due to distribution shifts and privacy concerns.
method Derives efficient influence functions, incorporates machine learning, and proposes data-adaptive strategies.
result Achieves parametric rates of convergence to nominal coverage probabilities for prediction intervals.
Study compares ARIMA, ETS, NNAR and hybrids for COVID-19 hospitalizations.
problem Forecasting the second wave of COVID-19 hospitalizations in Italy.
method ARIMA, ETS, NNAR, and hybrid models.
result Hybrid models outperform single models in capturing epidemic patterns.