Paper shows federated learning can train models on private data.
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Study improves mortality prediction in hospital patients using comprehensive feature engineering.
This study shows unstructured clinical notes can improve mortality prediction.
Febrile neutropenia (FN) has been associated with high mortality, especially among adults with cancer. Understanding the patient and provider level heterogeneity in FN hospital admissions has potential to inform personalized interventions focused on increasing survival of individuals with FN. We leverage machine learni…
Bayesian optimization improves classifier selection for acute infection and mortality.
Machine learning predicts trauma patient mortality risk.
In healthcare, patient risk stratification models are often learned using time-series data extracted from electronic health records. When extracting data for a clinical prediction task, several formulations exist, depending on how one chooses the time of prediction and the prediction horizon. In this paper, we show how…
Study develops an interpretable model for early mortality prediction in elderly MODS patients.
Background: Palliative care is referred to a set of programs for patients that suffer life-limiting illnesses. These programs aim to guarantee a minimum level of quality of life (QoL) for the last stage of life. They are currently based on clinical evaluation of risk of one-year mortality. Objectives: The main objectiv…
Study develops a dynamic risk model for COVID-19 mortality using UK Biobank data.
Early hospital mortality prediction is critical as intensivists strive to make efficient medical decisions about the severely ill patients staying in intensive care units. As a result, various methods have been developed to address this problem based on clinical records. However, some of the laboratory test results are…
A new model predicts in-hospital mortality from EHR data, handling missing values with uncertainty.
Acute Kidney Injury (AKI), a sudden decline in kidney function, is associated with increased mortality, morbidity, length of stay, and hospital cost. Since AKI is sometimes preventable, there is great interest in prediction. Most existing studies consider all patients and therefore restrict to features available in the…
Extracting actionable insight from Electronic Health Records (EHRs) poses several challenges for traditional machine learning approaches. Patients are often missing data relative to each other; the data comes in a variety of modalities, such as multivariate time series, free text, and categorical demographic informatio…
Over the past decades, both critical care and cancer care have improved substantially. Due to increased cancer-specific survival, we hypothesized that both the number of cancer patients admitted to the ICU and overall survival have increased since the millennium change. MIMIC-III, a freely accessible critical care data…
We present a generative approach to classify scarcely observed longitudinal patient trajectories. The available time series are represented as tensors and factorized using generative deep recurrent neural networks. The learned factors represent the patient data in a compact way and can then be used in a downstream clas…
Analyzes COVID-19 data to predict mortality, forecast spread, and optimize resource allocation.
Machine learning improves early detection of patient deterioration in Brazilian hospitals.
Paper proposes robust method to detect risk heterogeneity across ethnic groups.
Traditional methods for assessing illness severity and predicting in-hospital mortality among critically ill patients require time-consuming, error-prone calculations using static variable thresholds. These methods do not capitalize on the emerging availability of streaming electronic health record data or capture time…
Electronic medical records (EMRs) supports the development of machine learning algorithms for predicting disease incidence, patient response to treatment, and other healthcare events. But insofar most algorithms have been centralized, taking little account of the decentralized, non-identically independently distributed…
New scalable method balances hospital profit status and heart attack outcomes.
ICU readmission is associated with longer hospitalization, mortality and adverse outcomes. An early recognition of ICU re-admission can help prevent patients from worse situation and lower treatment cost. As the abundance of Electronics Health Records (EHR), it is popular to design clinical decision tools with machine …
Robust policies improve ICU transfer outcomes by predicting patient deterioration.
Monitoring patients in ICU is a challenging and high-cost task. Hence, predicting the condition of patients during their ICU stay can help provide better acute care and plan the hospital's resources. There has been continuous progress in machine learning research for ICU management, and most of this work has focused on…
Deep neural networks have shown promising results for various clinical prediction tasks such as diagnosis, mortality prediction, predicting duration of stay in hospital, etc. However, training deep networks -- such as those based on Recurrent Neural Networks (RNNs) -- requires large labeled data, high computational res…
AdaptHetero uses MLI to tailor EHR models for subgroup-specific predictions.
Method uses random forest with distance covariance for transfer learning in healthcare.
Machine learning for healthcare often trains models on de-identified datasets with randomly-shifted calendar dates, ignoring the fact that data were generated under hospital operation practices that change over time. These changing practices induce definitive changes in observed data which confound evaluations which do…
Study evaluates approaches to improve worst-case model performance across patient subpopulations.
Study compares federated and centralized learning for patient data privacy.
condLSTM-Q predicts COVID-19 deaths at county level with quantile forecasts.
While the volume of electronic health records (EHR) data continues to grow, it remains rare for hospital systems to capture dense physiological data streams, even in the data-rich intensive care unit setting. Instead, typical EHR records consist of sparse and irregularly observed multivariate time series, which are wel…
Machine learning approaches have been effective in predicting adverse outcomes in different clinical settings. These models are often developed and evaluated on datasets with heterogeneous patient populations. However, good predictive performance on the aggregate population does not imply good performance for specific …
Italy's daily COVID-19 cases stratified by age groups.
There is growing interest in applying machine learning methods to Electronic Medical Records (EMR). Across different institutions, however, EMR quality can vary widely. This work investigated the impact of this disparity on the performance of three advanced machine learning algorithms: logistic regression, multilayer p…
Blood lactate concentration is a strong indicator of mortality risk in critically ill patients. While frequent lactate measurements are necessary to assess patient's health state, the measurement is an invasive procedure that can increase risk of hospital-acquired infections. For this reason we formally define the prob…
Preterm births occur at an alarming rate of 10-15%. Preemies have a higher risk of infant mortality, developmental retardation and long-term disabilities. Predicting preterm birth is difficult, even for the most experienced clinicians. The most well-designed clinical study thus far reaches a modest sensitivity of 18.2-…
Demographic projections of future mortality rates involve a high level of uncertainty and require stochastic mortality models. The current paper investigates forward mortality models driven by a (possibly infinite dimensional) Wiener process and a compensated Poisson random measure. A major innovation of the paper is t…
With a mortality rate of 5.4 million lives worldwide every year and a healthcare cost of more than 16 billion dollars in the USA alone, sepsis is one of the leading causes of hospital mortality and an increasing concern in the ageing western world. Recently, medical and technological advances have helped re-define the …
Many in-hospital mortality risk prediction scores dichotomize predictive variables to simplify the score calculation. However, hard thresholding in these additive stepwise scores of the form "add x points if variable v is above/below threshold t" may lead to critical failures. In this paper, we seek to develop risk pre…
Though black-box predictors are state-of-the-art for many complex tasks, they often fail to properly quantify predictive uncertainty and may provide inappropriate predictions for unfamiliar data. Instead, we can learn more reliable models by letting them either output a prediction set or abstain when the uncertainty is…
Cointegration helps insurers understand long-range mortality patterns.
New model incorporates long-range dependence in mortality rates for better valuation and risk management.
Paper assesses how pandemic data impacts mortality models.
Bayesian models forecast COVID-19 hospitalizations at single sites.
New approach models individual vitality for better mortality predictions.
Study predicts future hospitalizations to manage COVID-19 patient surge.