Study predicts heart failure patient survival using stacked ensemble ML.
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Interpretable survival analysis improves heart failure risk prediction.
Causal analysis reveals regional discrepancies in TOPCAT trial results.
Cardiotoxicity related to cancer therapies has become a serious issue, diminishing cancer treatment outcomes and quality of life. Early detection of cancer patients at risk for cardiotoxicity before cardiotoxic treatments and providing preventive measures are potential solutions to improve cancer patients's quality of …
The paper investigates causal relationships in heart failure prediction using machine learning.
Electronic health records (EHR) are increasingly being used for constructing disease risk prediction models. Feature engineering in EHR data however is challenging due to their highly dimensional and heterogeneous nature. Low-dimensional representations of EHR data can potentially mitigate these challenges. In this pap…
Proposes a framework for personalized treatment recommendations using observational data.
Random shuffle method boosts HF dataset size 10-21 times.
In this paper we present a Recurrent neural networks (RNN) based architecture that achieves an AUCROC of 0.9147 for predicting the onset of Congestive Heart Failure (CHF) 15 months in advance using a 12-month observation window on a large cohort of 216,394 patients. We believe this to be the largest study in CHF onset …
Bayesian model identifies health disparities in disease progression.
We developed a new approach for the analysis of physiological time series. An iterative convolution filter is used to decompose the time series into various components. Statistics of these components are extracted as features to characterize the mechanisms underlying the time series. Motivated by the studies that show …
Deep learning models exhibit state-of-the-art performance for many predictive healthcare tasks using electronic health records (EHR) data, but these models typically require training data volume that exceeds the capacity of most healthcare systems. External resources such as medical ontologies are used to bridge the da…
Heart failure hospitalization is a severe burden on healthcare. How to predict and therefore prevent readmission has been a significant challenge in outcomes research. To address this, we propose a deep learning approach to predict readmission from clinical notes. Unlike conventional methods that use structured data fo…
Deep learning methods exhibit promising performance for predictive modeling in healthcare, but two important challenges remain: -Data insufficiency:Often in healthcare predictive modeling, the sample size is insufficient for deep learning methods to achieve satisfactory results. -Interpretation:The representations lear…
The growth of data, the need for scalability and the complexity of models used in modern machine learning calls for distributed implementations. Yet, as of today, distributed machine learning frameworks have largely ignored the possibility of arbitrary (i.e., Byzantine) failures. In this paper, we study the robustness …
A new method reduces the computational cost of Sinkhorn algorithm for OT and UOT problems.
Phenotyping electronic health records (EHR) focuses on defining meaningful patient groups (e.g., heart failure group and diabetes group) and identifying the temporal evolution of patients in those groups. Tensor factorization has been an effective tool for phenotyping. Most of the existing works assume either a static …
Paper proposes a new method for uncertainty estimation in medical data.
New approach combines invariance and information bottleneck for OOD generalization.
In this work, a novel approach is proposed for joint analysis of high dimensional time-resolved cardiac motion features obtained from segmented cardiac MRI and low dimensional clinical risk factors to improve survival prediction in heart failure. Different methods are evaluated to find the optimal way to insert convent…
Objectives: Atrial fibrillation (AF) is a common heart rhythm disorder associated with deadly and debilitating consequences including heart failure, stroke, poor mental health, reduced quality of life and death. Having an automatic system that diagnoses various types of cardiac arrhythmias would assist cardiologists to…
Heart diseases constitute a global health burden, and the problem is exacerbated by the error-prone nature of listening to and interpreting heart sounds. This motivates the development of automated classification to screen for abnormal heart sounds. Existing machine learning-based systems achieve accurate classificatio…
Framework for imputing missing heart data to simulate brain-heart interactions.
Stability in clinical prediction models is crucial for transferability between studies, yet has received little attention. The problem is paramount in high dimensional data which invites sparse models with feature selection capability. We introduce an effective method to stabilize sparse Cox model of time-to-events usi…
We consider the problem of locating a point-source heart arrhythmia using data from a standard diagnostic procedure, where a reference catheter is placed in the heart, and arrival times from a second diagnostic catheter are recorded as the diagnostic catheter moves around within the heart. We model this situation as a …
Improved heart rate and activity recognition with low-power wrist sensors.
To date, the instability of prognostic predictors in a sparse high dimensional model, which hinders their clinical adoption, has received little attention. Stable prediction is often overlooked in favour of performance. Yet, stability prevails as key when adopting models in critical areas as healthcare. Our study propo…
Heart disease is the leading cause of death, and experts estimate that approximately half of all heart attacks and strokes occur in people who have not been flagged as "at risk." Thus, there is an urgent need to improve the accuracy of heart disease diagnosis. To this end, we investigate the potential of using data ana…
Continuous, ubiquitous monitoring through wearable sensors has the potential to collect useful information about users' context. Heart rate is an important physiologic measure used in a wide variety of applications, such as fitness tracking and health monitoring. However, wearable sensors that monitor heart rate, such …
Photoplethysmogram (PPG) is increasingly used to provide monitoring of the cardiovascular system under ambulatory conditions. Wearable devices like smartwatches use PPG to allow long term unobtrusive monitoring of heart rate in free living conditions. PPG based heart rate measurement is unfortunately highly susceptible…
The electronic health record (EHR) provides an unprecedented opportunity to build actionable tools to support physicians at the point of care. In this paper, we investigate survival analysis in the context of EHR data. We introduce deep survival analysis, a hierarchical generative approach to survival analysis. It depa…
The widespread availability of electronic health records (EHRs) promises to usher in the era of personalized medicine. However, the problem of extracting useful clinical representations from longitudinal EHR data remains challenging. In this paper, we explore deep neural network models with learned medical feature embe…
Proposes a novel anomaly detection method for echocardiogram videos.
AI-assisted heart disease diagnosis reduces misdiagnosis and saves lives.
A new prior for VAEs improves model capacity by allowing a more flexible latent space.
Novel method segments heart sound signals using LSTMs with attention.
We develop a model to cluster time-series data with interval censoring, improving disease phenotyping.
Cardiovascular Disease (CVD) is considered as one of the principal causes of death in the world. Over recent years, this field of study has attracted researchers' attention to investigate heart sounds' patterns for disease diagnostics. In this study, an approach is proposed for normal/abnormal heart sound classificatio…
This paper proposes a framework based on deep convolutional neural networks (CNNs) for automatic heart sound classification using short-segments of individual heart beats. We design a 1D-CNN that directly learns features from raw heart-sound signals, and a 2D-CNN that takes inputs of two- dimensional time-frequency fea…
Generating datasets that "look like" given real ones is an interesting tasks for healthcare applications of ML and many other fields of science and engineering. In this paper we propose a new method of general application to binary datasets based on a method for learning the parameters of a latent variable moment that …
Developed shrinkage methods for Poisson regression models with experts to handle multicollinearity.
Study examines heart and football-shaped metrics, verifying geometric structure.
The study examines machine learning classification algorithms and their generalizability using Framingham Heart Study data.
The assessment of energy expenditure in real life is of great importance for monitoring the current physical state of people, especially in work, sport, elderly care, health care, and everyday life even. This work reports about application of some machine learning methods (linear regression, linear discriminant analysi…
Effective modeling of electronic health records (EHR) is rapidly becoming an important topic in both academia and industry. A recent study showed that using the graphical structure underlying EHR data (e.g. relationship between diagnoses and treatments) improves the performance of prediction tasks such as heart failure…
Machine learning improves CHD screening accuracy from 70% to 87.7%.
Improved robustness of 1D CNNs for heart arrhythmia classification.
Economics tool predicts failure times in reliability systems.