New diagnostics detect variability in individual risk estimates from machine learning models in healthcare.
problem Variability in individual risk estimates from machine learning models in healthcare, leading to unreliable treatment decisions.
method Proposed evaluation framework using empirical prediction interval width and empirical decision flip rate diagnostics.
result Randomness in optimization and initialization can lead to substantial individual-level variability in risk estimates, affecting clinical decisions.
Study highlights robustness issues in healthcare diagnostic models due to distribution shifts.
problem Robustness of diagnostic models in healthcare is compromised by distribution shifts.
method Theoretical analysis and simulation studies to understand and mitigate shortcuts learned by models.
result Ignoring covariates or using invariant learning approaches leads to non-robust predictors.
Reducing ICD-10 code granularity improves cost model accuracy and stability.
problem High-dimensional regression with ICD-10 codes leads to unstable coefficient estimates.
method Log-linear analytics approach to cost model regularization through diagnostic code merging.
result Reducing ICD-10 code granularity from 7 characters to 6 or fewer improves model interpretability and consistency.
AI predicts medical specialty diagnostic choices from EHR records.
problem Predicting timely medical specialty diagnostic workups for patients.
method Ensemble of feed-forward neural networks trained on EHR data.
result Significantly higher accuracy compared to traditional checklists.
High quality risk adjustment in health insurance markets weakens insurer incentives to engage in inefficient behavior to attract lower-cost enrollees. We propose a novel methodology based on Markov Chain Monte Carlo methods to improve risk adjustment by clustering diagnostic codes into risk groups optimal for health ex…
Paper detects biases in medical imaging ML models using counterfactual analysis.
problem Bias in medical imaging ML models negatively impacts generalization performance.
method Counterfactual invariance framework combining conditional latent diffusion models and statistical hypothesis testing.
result The method identifies and quantifies biases without direct access to counterfactual data.
Develops privacy-preserving methods for equivalence testing in healthcare.
problem Protecting patient data in healthcare studies.
method Differential privacy techniques for simulation-based calibration.
result Maintains type-I error control and comparable power to non-private methods.
Lung cancer continues to be a major healthcare challenge with high morbidity and mortality rates among both men and women worldwide. The majority of lung cancer cases are of non-small cell lung cancer type. With the advent of targeted cancer therapy, it is imperative not only to properly diagnose but also sub-classify …
In this paper, we aimed at reviewing several different approaches present today in the search for more accurate diagnostic and treatment management in mental healthcare. Our focus is on mood disorders, and in particular on the major depressive disorder (MDD). We are reviewing and discussing findings based on neuroimagi…
Two new feature selection methods improve breast cancer diagnosis accuracy.
problem Improving breast cancer diagnosis accuracy and reducing dataset dimensions.
method Imperialist Competitive Algorithm (ICA) and Bat Algorithm (BA) integrated with ML algorithms.
result BA-based feature selection method outperforms other methods with 99.12% accuracy.
Generating datasets that "look like" given real ones is an interesting tasks for healthcare applications of ML and many other fields of science and engineering. In this paper we propose a new method of general application to binary datasets based on a method for learning the parameters of a latent variable moment that …
Portable, Wearable and Wireless electrocardiogram (ECG) Systems have the potential to be used as point-of-care for cardiovascular disease diagnostic systems. Such wearable and wireless ECG systems require automatic detection of cardiovascular disease. Even in the primary care, automation of ECG diagnostic systems will …
Paper uses AI to predict medications from medical codes, improving accuracy in healthcare.
problem Predicting medications from incomplete or incorrect medical codes is challenging.
method Robust Recurrent Neural Networks (RNNs) with decay mechanism and noise injection.
result The method accurately predicts medication orders from contaminated medical codes.
Bayesian CNN estimates uncertainty in COVID-19 detection.
problem Uncertainty in deep learning predictions for medical diagnosis.
method Drop-weight based Bayesian Convolutional Neural Networks (BCNN).
result Uncertainty correlates with prediction accuracy.
Machine-learned diagnosis models have shown promise as medical aides but are trained under a closed-set assumption, i.e. that models will only encounter conditions on which they have been trained. However, it is practically infeasible to obtain sufficient training data for every human condition, and once deployed such …
In healthcare applications, temporal variables that encode movement, health status and longitudinal patient evolution are often accompanied by rich structured information such as demographics, diagnostics and medical exam data. However, current methods do not jointly optimize over structured covariates and time series …
This paper reviews early time series classification methods.
problem Minimizing class prediction delay in time-sensitive applications.
method Divided into four categories: prefix based, shapelet based, model based, and miscellaneous approaches.
result Demonstrates reasonable performance in various applications.
. In this paper, an effective computer-aided diagnosis (CAD) system is presented to detect MI signals using the convolution neural network (CNN) for urban healthcare in smart cities. Two types of transfer learning techniques are employed to retrain the pre-trained VGG-Net (Fine-tuning and VGG-Net as fixed feature extra…
Study evaluates federated learning with differential privacy on MIMIC-III, improving model performance with careful parameter tuning.
problem Training machine learning models on privacy-sensitive data sets locked in healthcare facilities.
method Extensive evaluation of federated and differential privacy techniques on MIMIC-III dataset, analyzing various parameters.
result Careful parameter tuning is crucial for federated learning with differential privacy, especially for data distribution and communication strategies.
Risk adjustment has become an increasingly important tool in healthcare. It has been extensively applied to payment adjustment for health plans to reflect the expected cost of providing coverage for members. Risk adjustment models are typically estimated using linear regression, which does not fully exploit the informa…
Smartphone app diagnoses pulmonary diseases from chest X-rays.
problem Scarcity of training data and class imbalance issues.
method Data Augmentation Generative Adversarial Network (DAGAN) and Convolutional Siamese Network with attention mechanism.
result Achieved 99.30% and 98.40% testing accuracy on Binary/Multiclass scenarios.
Estimates vaccine effectiveness and immune correlates in TND studies with missing data.
problem Confounding and missing data in TND studies of vaccine effectiveness and immune correlates.
method Targeted maximum likelihood estimation using a semiparametric logistic regression model.
result Valid causal inference of vaccine effectiveness and immune correlates in TND studies with missing exposure data.
New estimator uses clustering to improve off-policy evaluation accuracy.
problem Improving off-policy evaluation accuracy when logging and evaluation policies differ.
method Proposes an estimator that shares information across similar contexts using clustering.
result Clustering contexts improves estimation accuracy, especially in deficient information settings.
A new HP model balances interpretability and flexibility for EHR event sequences.
problem Balancing interpretability and flexibility in modeling diagnostic event sequences.
method Proposes a neural network-based HP with flexible impact kernel and transformer layers.
result Accurately recovers impact functions, competitive performance, and clinically meaningful interpretation.
This paper introduces a novel low-cost device prototype for the automatic diagnosis of diseases, utilizing inputted symptoms and personal background. The engineering goal is to solve the problem of limited healthcare access with a single device. Diagnosing diseases automatically is an immense challenge, owing to their …
Probabilistic ML improves healthcare data analysis.
problem Insufficient understanding and incomplete data in healthcare.
method Examination of probabilistic machine learning models for healthcare challenges.
result Probabilistic models enhance healthcare data analysis and model building.
Applying machine learning in the health care domain has shown promising results in recent years. Interpretable outputs from learning algorithms are desirable for decision making by health care personnel. In this work, we explore the possibility of utilizing causal relationships to refine diagnostic prediction. We focus…
Establishes statistical and computational bounds for influence diagnostics.
problem Identifying influential datapoints or subsets in machine learning models.
method Finite-sample statistical bounds and computational complexity for influence functions and approximate maximum influence perturbations.
result Established statistical and computational guarantees for influence diagnostics.
A statistical description and model of individual healthcare expenditures in the US has been developed for measuring value in healthcare. We find evidence that healthcare expenditures are quantifiable as an infusion-diffusion process, which can be thought of intuitively as a steady change in the intensity of treatment …
The article explains how to estimate confusion matrices for classifiers using unlabeled data.
problem Estimating sensitivity and specificity of binary medical diagnostic tests without gold standard tests.
method Modifying diagnostic test solutions to estimate confusion matrices for classifiers on unlabeled data.
result The approach can be used to estimate accuracy statistics for supervised or unsupervised binary classifiers on unlabeled data.
Intricating cardiac complexities are the primary factor associated with healthcare costs and the highest cause of death rate in the world. However, preventive measures like the early detection of cardiac anomalies can prevent severe cardiovascular arrests of varying complexities and can impose a substantial impact on h…
Big data analytics improves healthcare through early detection and quality life.
problem Limited access to healthcare data hinders evidence-based decision-making.
method Analysis of healthcare data using various tools and techniques.
result Big data analytics enhances healthcare quality and patient outcomes.
Doctors often rely on their past experience in order to diagnose patients. For a doctor with enough experience, almost every patient would have similarities to key cases seen in the past, and each new patient could be viewed as a mixture of these key past cases. Because doctors often tend to reason this way, an efficie…
Clinical prognostic models derived from largescale healthcare data can inform critical diagnostic and therapeutic decisions. To enable off-theshelf usage of machine learning (ML) in prognostic research, we developed AUTOPROGNOSIS: a system for automating the design of predictive modeling pipelines tailored for clinical…
AI enhances cancer diagnostics using spectroscopy.
problem Early and accurate cancer diagnosis.
method Combining AI with spectroscopy-based techniques.
result AI improves cancer diagnostics speed and safety.
Survey on securing ML for healthcare, addressing privacy and robustness issues.
problem Security and robustness challenges in healthcare ML/DL applications.
method Overview of security and privacy methods for ML in healthcare.
result Discussion of current research challenges and future directions.
Paper introduces a diagnostic for approximate inference methods.
problem Estimating errors in probabilistic inference algorithms, especially for approximate methods.
method Repeatedly simulate datasets from the prior and perform inference on each, estimating a symmetric KL-divergence.
result A diagnostic for approximate inference methods can be estimated using symmetric KL-divergence.
Machine learning improves diagnostic test accuracy for bovine tuberculosis.
problem Improving diagnostic test sensitivity for bovine tuberculosis.
method Machine learning to assess risk landscapes and predict infection.
result Test sensitivity improved, detecting 240 more infected herds per year.
One of the main issues affecting the Italian NHS is the healthcare deficit: according to current agreements between the Italian State and its Regions, public funding of regional NHS is now limited to the amount of regional deficit and is subject to previous assessment of strict adherence to constraint on regional healt…
With the advent of smartphone indirect ophthalmoscopy, teleophthalmology - the use of specialist ophthalmology assets at a distance from the patient - has experienced a breakthrough, promising enormous benefits especially for healthcare in distant, inaccessible or opthalmologically underserved areas, where specialists …
This paper solves the problem of optimal dynamic consumption, investment, and healthcare spending with isoelastic utility, when natural mortality grows exponentially to reflect Gompertz' law and investment opportunities are constant. Healthcare slows the natural growth of mortality, indirectly increasing utility from c…
Study optimal healthcare spending under Epstein-Zin preferences for longevity.
problem Optimizing healthcare spending to extend longevity under Epstein-Zin preferences.
method Formulated Epstein-Zin utilities over a controllable random horizon using backward stochastic differential equations and HJB equations.
result Calibrated model accurately reflects actual mortality data and compares healthcare efficacy between countries.
Bayesian optimization improves classifier selection for acute infection and mortality.
problem Improving accuracy of acute infection and mortality prediction.
method Comparison of hyperparameter optimization methods (grid search, random sampling, Bayesian optimization).
result Bayesian optimization outperforms grid search or random sampling for in-hospital mortality classifiers.
Study improves conformal prediction for EEG classification in healthcare, enhancing coverage.
problem Uncertainty quantification in clinical predictions, especially in distribution-shifted settings.
method Personalized calibration strategies to improve coverage of prediction sets.
result Coverage improved by over 20 percentage points with comparable prediction set sizes.
Feature selection, which searches for the most representative features in observed data, is critical for health data analysis. Unlike feature extraction, such as PCA and autoencoder based methods, feature selection preserves interpretability, meaning that the selected features provide direct information about certain h…
A recommendation framework helps users choose healthcare interventions.
problem Choice overload in online healthcare communities.
method Multi-Armed Bandit (MAB) approach with innovative model components.
result Our recommendation design outperforms state-of-the-art systems.
Interpretability of ML models improves healthcare decisions.
problem Ensuring machine learning models are understandable for healthcare users.
method Classifying interpretability into local and global approaches, and model-specific vs. model-agnostic methods.
result Examples of practical interpretability in healthcare, including prediction and treatment optimization.
Graph-based approach repairs programs from diagnostic feedback.
problem Learning to repair programs from limited labeled data and compiler error messages.
method Introduces program-feedback graph and graph neural network for reasoning, and self-supervised learning with unlabeled programs.
result DrRepair significantly outperforms prior work, achieving high repair rates.