Interpretability of ML models improves healthcare decisions.
problem Ensuring machine learning models are understandable for healthcare users.
method Classifying interpretability into local and global approaches, and model-specific vs. model-agnostic methods.
result Examples of practical interpretability in healthcare, including prediction and treatment optimization.
Hybrid Bayesian-conformal framework improves uncertainty quantification in healthcare predictions.
problem Jointly satisfying distribution-free coverage guarantees and risk-adaptive precision in clinical decision-making.
method Integrates Bayesian hierarchical random forests with group-aware conformal calibration, using posterior uncertainties to weight conformity scores.
result Achieves target coverage (94.3% vs 95% target) with adaptive precision, 21% narrower intervals for low-uncertainty cases.
Paper analyzes uncertainty metrics in ensemble learning for healthcare AI.
problem Selecting appropriate uncertainty metrics for ensemble learners in healthcare AI.
method Rigorous analysis of two uncertainty metrics: ensemble mean and variance.
result Ensemble mean is preferable to ensemble variance for decision making in healthcare AI.
MCU-Net combines U-Net and Monte Carlo Dropout for uncertainty in medical image segmentation.
problem Lack of uncertainty representation in deep learning methods for patient-centered healthcare decisions.
method MCU-Net framework using U-Net and Monte Carlo Dropout with four uncertainty metrics.
result MCU-Net maximizes automated performance and refers truly uncertain cases.
In the modern healthcare system, rapidly expanding costs/complexity, the growing myriad of treatment options, and exploding information streams that often do not effectively reach the front lines hinder the ability to choose optimal treatment decisions over time. The goal in this paper is to develop a general purpose (…
LUQ-Learning adapts Q-learning for healthcare decisions considering patient preferences.
problem Optimizing treatment decisions for multivariate outcomes based on individual preferences.
method Latent Utility Q-Learning (LUQ-Learning) framework that adapts Q-learning for composite outcomes.
result LUQ-Learning achieves highly competitive performance compared to alternative methods in simulations.
A contextual care protocol is used by a medical practitioner for patient healthcare, given the context or situation that the specified patient is in. This paper proposes a method to build an automated self-adapting protocol which can help make relevant, early decisions for effective healthcare delivery. The hybrid mode…
A new reinforcement learning method for medical decisions with limited data.
problem Learning high-performing policies from partially observed data in healthcare.
method Optimization objective that combines policy and generative model quality, suitable for batch off-policy settings.
result Demonstrated improved performance on synthetic and medical decision-making problems.
A new RL approach learns near-equivalent actions for healthcare decisions.
problem Finding optimal actions in healthcare settings where actions may be near-equivalent.
method Temporal difference learning with a near-greedy heuristic for action selection.
result The proposed algorithm discovers meaningful near-equivalent actions and converges well.
New diagnostics detect variability in individual risk estimates from machine learning models in healthcare.
problem Variability in individual risk estimates from machine learning models in healthcare, leading to unreliable treatment decisions.
method Proposed evaluation framework using empirical prediction interval width and empirical decision flip rate diagnostics.
result Randomness in optimization and initialization can lead to substantial individual-level variability in risk estimates, affecting clinical decisions.
Strategic feature selection in high-stakes domains like healthcare.
problem Strategic manipulation of input features in algorithmic predictors.
method Formal study of strategic classification through feature selection and ridge regularization.
result Excluding individual features based on manipulability is generally suboptimal.
Unified RL survey for healthcare AI interventions.
problem Limited real-life application of RL in healthcare.
method Unified technical survey and case studies.
result Bridge between dynamic treatment regimes and mobile health.
The paper proposes a fair reinforcement learning framework to prevent healthcare disparities.
problem Unfair reinforcement learning policies in healthcare can lead to socioeconomically-disadvantaged subgroups being underprivileged.
method The paper introduces a counterfactual fairness framework and a sequential data preprocessing algorithm to achieve fair sequential decision making.
result The proposed approach greatly enhances fair access to counseling in a digital health dataset designed to reduce opioid misuse.
Method learns evolving policies in healthcare contexts.
problem Understanding non-stationary behavior in evolving decision-making processes.
method Inverse Contextual Bandits (ICB) approach for learning interpretable representations of non-stationary behavior.
result Demonstrated applicability and accuracy of ICB method in liver transplantation policies.
Big data analytics improves healthcare through early detection and quality life.
problem Limited access to healthcare data hinders evidence-based decision-making.
method Analysis of healthcare data using various tools and techniques.
result Big data analytics enhances healthcare quality and patient outcomes.
RSM provides insights into deep survival models' decision-making.
problem Ensuring trust in deep survival models' predictions for healthcare applications.
method Reverse survival model (RSM) framework that explains deep survival models' decisions.
result RSM extracts relevant features for deep survival models' predictions.
New method estimates policy performance under unobserved confounding.
problem Estimating policy performance when decisions depend on unobserved variables.
method Developed worst-case bounds for robust OPE under unobserved confounding.
result Efficient procedure for computing worst-case bounds, proving statistical consistency.
Proposes a method to improve rare event prediction in healthcare.
problem Rare event classification in healthcare with low prevalence labels.
method Variational disentanglement approach to semi-parametric learning.
result Outperforms existing alternatives in mortality prediction on COVID-19 cohort.
Improves off-policy evaluation with imperfect annotations.
problem Limited dataset coverage for evaluating new policies.
method Doubly robust estimators combining IS and DM, incorporating counterfactual annotations.
result Using annotations within the DM component yields the most desirable theoretical results.
Black box machine learning models are currently being used for high stakes decision-making throughout society, causing problems throughout healthcare, criminal justice, and in other domains. People have hoped that creating methods for explaining these black box models will alleviate some of these problems, but trying t…
Unified framework for imputation and prediction in healthcare time series.
problem Time misalignment and data sparsity in healthcare time series.
method MAGIC (Multi-tAsk Gaussian Process for Imputation and Classification) using hierarchical multi-task Gaussian process and functional logistic regression.
result Superior predictive accuracy compared to existing methods in two healthcare applications.
RL platform enhances user journeys in healthcare apps.
problem Improving user experience and personalization in healthcare apps.
method Reinforcement learning framework for adaptive interventions.
result Significant increase in basket size through personalized recommendations.
PNNs improve personalized healthcare policies using mixed integer programming.
problem Learning treatment policies for patients with limited data.
method Prescriptive networks (PNNs) trained with mixed integer programming.
result PNNs outperform existing methods in reducing peak blood pressure.
In many healthcare settings, intuitive decision rules for risk stratification can help effective hospital resource allocation. This paper introduces a novel variant of decision tree algorithms that produces a chain of decisions, not a general tree. Our algorithm, α-Carving Decision Chain (ACDC), sequentially carves o…
Causal thinking improves healthcare decisions from EHRs.
problem Shortcuts in data lead to biased healthcare decisions.
method Step-by-step framework for valid decision making from EHRs.
result Valid decision making requires careful analysis of EHR data.
A recommendation framework helps users choose healthcare interventions.
problem Choice overload in online healthcare communities.
method Multi-Armed Bandit (MAB) approach with innovative model components.
result Our recommendation design outperforms state-of-the-art systems.
Optimal healthcare investment timing in a dynamic model with mortality risk.
problem Optimal timing of healthcare investment to reduce mortality risk.
method Dynamic framework, stochastic control, optimal stopping problem, dual transformation.
result Characterization of the optimal investment boundary and numerical solutions.
Study improves mortality prediction in hospital patients using comprehensive feature engineering.
problem Accurate prediction of all-cause in-hospital mortality in healthcare.
method Comprehensive feature engineering approach using vital signs, laboratory results, and demographic data.
result Random Forest model achieved highest performance with AUC of 0.94, significantly outperforming other models.
This tutorial evaluates machine learning for healthcare applications.
problem Unrealistic expectations in healthcare AI development.
method Practical guidance on performance evaluation criteria and common mistakes.
result Better understanding and avoidance of common traps in AI healthcare.
A new method uses active learning to improve bile duct stone evaluation.
problem Efficiently collecting necessary patient data in sequential healthcare decisions.
method Developed an active learning-based multistage sequential decision-making model.
result Improves estimation efficiency by 62%-1838% compared to baseline methods.
The paper tackles optimal policy learning with asymmetric counterfactual utilities in healthcare decisions.
problem Learning optimal policies from observed data with asymmetric counterfactual utilities.
method The approach involves identifying and minimizing the maximum expected utility loss using statistical decision theory and solving intermediate classification problems.
result One can learn minimax loss decision rules from observed data.
Research predicts healthcare index movements using historical OHLC data.
problem Predicting the directional movement of healthcare indices based on historical data.
method Supervised classification task with a one-step-ahead rolling window, using a diverse feature set including OHLC ratios.
result Robust predictive performance with accuracy exceeding 0.8 and Matthews correlation coefficients above 0.6, highlighting the importance of nowcasting features.
New method handles uncertainty in causal effect estimation for better decision-making.
problem Handling uncertainty in causal effect estimation, especially in high-dimensional data and covariate shift.
method Integrates uncertainty estimation into neural network methods for individual-level causal estimates.
result Uncertainty-aware methods improve decision-making by alerting when predictions are not reliable.
The paper studies causal effects of multiple treatments in healthcare databases with rare outcomes.
problem Estimating causal effects of multiple treatments in healthcare databases with rare outcomes.
method The paper designs three sets of simulations and compares the operating characteristics of three types of methods: Bayesian Additive Regression Trees (BART), regression adjustment on multivariate spline of generalized propensity scores (RAMS), and inverse probability of treatment weighting (IPTW) with multinomial logistic regression or generalized boosted models.
result BART and RAMS provide lower bias and mean squared error compared to IPTW methods.
Framework for AI healthcare products from concept to market.
problem Failure of AI products to reach clinics despite promising potential.
method Decision-making framework for AI healthcare product development.
result Guides through a three-phase process to market launch of validated AI products.
Exponential growth in Electronic Healthcare Records (EHR) has resulted in new opportunities and urgent needs for discovery of meaningful data-driven representations and patterns of diseases in Computational Phenotyping research. Deep Learning models have shown superior performance for robust prediction in computational…
Meta-learning interpretable decision trees with synthetic data.
problem Lack of efficient, scalable methods for generating synthetic data for decision tree meta-learning.
method Synthetic generation of near-optimal decision trees using the MetaTree transformer architecture.
result Meta-learning of decision trees achieves performance comparable to real-world data or optimal decision trees, with significant computational cost reduction.
Study uses healthcare claims data to identify Covid-19 risk factors without prior selection.
problem Identify risk factors for severe Covid-19 cases.
method Fine-grained hierarchical information from medical classification systems used to analyze over 33,000 covariates.
result Method has better predictive ability than pre-specified morbidity groups.
Study finds incorporating fairness in healthcare models doesn't improve performance or net benefit.
problem Addressing health inequities in healthcare through algorithmic fairness.
method Empirical case study using models to estimate atherosclerotic cardiovascular disease risk.
result Incorporating fairness considerations into model training objective does not improve model performance or net benefit.
Neural TPPs improve EHR modelling efficiency.
problem Challenges in modelling irregularly timed, noisy EHRs.
method Proposed neural network parameterizations of Temporal Point Processes (TPPs) for EHRs.
result Neural TPPs outperform non-TPP models on EHRs.
ADHAM provides interpretable survival analysis for healthcare.
problem Limited interpretability in deep learning survival models.
method Additive Deep Hazard Analysis Mixtures (ADHAM) with latent subgroup structure.
result ADHAM offers interpretable insights into exposure-outcome associations.
The paper proposes a method to calibrate healthcare AI models for reliability and interpretability.
problem Characterizing model reliability and enabling introspection of model behavior in clinical decision making.
method A calibration-driven learning method combined with interpretability techniques based on counterfactual reasoning.
result Demonstrates the effectiveness of the proposed approach using a lesion classification problem with dermoscopy images.
Life-expectancy is a complex outcome driven by genetic, socio-demographic, environmental and geographic factors. Increasing socio-economic and health disparities in the United States are propagating the longevity-gap, making it a cause for concern. Earlier studies have probed individual factors but an integrated pictur…
Deep learning analyzes healthcare provider actions and patient outcomes.
problem Understanding provider behavior in non-randomized healthcare settings.
method Deep causal behavioral policy learning (DC-BPL) using transformer architecture.
result Optimal provider policies identified for specific patient types.
Quantized BNNs maintain uncertainty estimation quality despite reduced precision.
problem Reduced precision in BNNs due to quantization.
method Quantized BNNs with 32-bit weights and activations compressed to 16-bit integers.
result Uniform quantization does not significantly degrade uncertainty estimation quality.
Much attention has been devoted recently to the development of machine learning algorithms with the goal of improving treatment policies in healthcare. Reinforcement learning (RL) is a sub-field within machine learning that is concerned with learning how to make sequences of decisions so as to optimize long-term effect…
This study proposes a method to predict ICU infections from imbalanced data using clustering-based undersampling and ensemble classifiers.
problem Predicting healthcare-associated infections in ICU patients from imbalanced data.
method Clustering-based undersampling strategy combined with ensemble classifiers.
result The proposed method outperforms other resampling techniques in predicting ICU infections.
Develops causal framework for fair survival analysis in healthcare.
problem Fairness in survival analysis for high-stakes domains like healthcare.
method Causal framework using graphical models, conditional survival function, and Causal Reduction Theorem.
result Decomposes disparities in survival into direct, indirect, and spurious pathways.