Paper analyzes uncertainty metrics in ensemble learning for healthcare AI.
problem Selecting appropriate uncertainty metrics for ensemble learners in healthcare AI.
method Rigorous analysis of two uncertainty metrics: ensemble mean and variance.
result Ensemble mean is preferable to ensemble variance for decision making in healthcare AI.
Interpretability of ML models improves healthcare decisions.
problem Ensuring machine learning models are understandable for healthcare users.
method Classifying interpretability into local and global approaches, and model-specific vs. model-agnostic methods.
result Examples of practical interpretability in healthcare, including prediction and treatment optimization.
Hybrid Bayesian-conformal framework improves uncertainty quantification in healthcare predictions.
problem Jointly satisfying distribution-free coverage guarantees and risk-adaptive precision in clinical decision-making.
method Integrates Bayesian hierarchical random forests with group-aware conformal calibration, using posterior uncertainties to weight conformity scores.
result Achieves target coverage (94.3% vs 95% target) with adaptive precision, 21% narrower intervals for low-uncertainty cases.
A new RL approach learns near-equivalent actions for healthcare decisions.
problem Finding optimal actions in healthcare settings where actions may be near-equivalent.
method Temporal difference learning with a near-greedy heuristic for action selection.
result The proposed algorithm discovers meaningful near-equivalent actions and converges well.
The paper proposes a fair reinforcement learning framework to prevent healthcare disparities.
problem Unfair reinforcement learning policies in healthcare can lead to socioeconomically-disadvantaged subgroups being underprivileged.
method The paper introduces a counterfactual fairness framework and a sequential data preprocessing algorithm to achieve fair sequential decision making.
result The proposed approach greatly enhances fair access to counseling in a digital health dataset designed to reduce opioid misuse.
A new reinforcement learning method for medical decisions with limited data.
problem Learning high-performing policies from partially observed data in healthcare.
method Optimization objective that combines policy and generative model quality, suitable for batch off-policy settings.
result Demonstrated improved performance on synthetic and medical decision-making problems.
RSM provides insights into deep survival models' decision-making.
problem Ensuring trust in deep survival models' predictions for healthcare applications.
method Reverse survival model (RSM) framework that explains deep survival models' decisions.
result RSM extracts relevant features for deep survival models' predictions.
Unified RL survey for healthcare AI interventions.
problem Limited real-life application of RL in healthcare.
method Unified technical survey and case studies.
result Bridge between dynamic treatment regimes and mobile health.
New method estimates policy performance under unobserved confounding.
problem Estimating policy performance when decisions depend on unobserved variables.
method Developed worst-case bounds for robust OPE under unobserved confounding.
result Efficient procedure for computing worst-case bounds, proving statistical consistency.
A contextual care protocol is used by a medical practitioner for patient healthcare, given the context or situation that the specified patient is in. This paper proposes a method to build an automated self-adapting protocol which can help make relevant, early decisions for effective healthcare delivery. The hybrid mode…
A new method uses active learning to improve bile duct stone evaluation.
problem Efficiently collecting necessary patient data in sequential healthcare decisions.
method Developed an active learning-based multistage sequential decision-making model.
result Improves estimation efficiency by 62%-1838% compared to baseline methods.
Exponential growth in Electronic Healthcare Records (EHR) has resulted in new opportunities and urgent needs for discovery of meaningful data-driven representations and patterns of diseases in Computational Phenotyping research. Deep Learning models have shown superior performance for robust prediction in computational…
Improves off-policy evaluation with imperfect annotations.
problem Limited dataset coverage for evaluating new policies.
method Doubly robust estimators combining IS and DM, incorporating counterfactual annotations.
result Using annotations within the DM component yields the most desirable theoretical results.
In the modern healthcare system, rapidly expanding costs/complexity, the growing myriad of treatment options, and exploding information streams that often do not effectively reach the front lines hinder the ability to choose optimal treatment decisions over time. The goal in this paper is to develop a general purpose (…
Interpole learns transparent decision-making policies from data.
problem Understanding human decision-making in opaque environments.
method Interpole combines belief-update and belief-action mapping estimation.
result Interpole provides interpretable models of decision-making behavior.
PNNs improve personalized healthcare policies using mixed integer programming.
problem Learning treatment policies for patients with limited data.
method Prescriptive networks (PNNs) trained with mixed integer programming.
result PNNs outperform existing methods in reducing peak blood pressure.
Causal thinking improves healthcare decisions from EHRs.
problem Shortcuts in data lead to biased healthcare decisions.
method Step-by-step framework for valid decision making from EHRs.
result Valid decision making requires careful analysis of EHR data.
New algorithm improves knowledge transfer in dynamic decision-making.
problem Utilizing data from existing ventures to improve decision-making in new ventures.
method Proposes Transferred Fitted Q-Iteration algorithm for estimating optimal action-state function Q∗. result Significantly improved final learning error of Q∗ function. Strategic feature selection in high-stakes domains like healthcare.
problem Strategic manipulation of input features in algorithmic predictors.
method Formal study of strategic classification through feature selection and ridge regularization.
result Excluding individual features based on manipulability is generally suboptimal.
Method learns evolving policies in healthcare contexts.
problem Understanding non-stationary behavior in evolving decision-making processes.
method Inverse Contextual Bandits (ICB) approach for learning interpretable representations of non-stationary behavior.
result Demonstrated applicability and accuracy of ICB method in liver transplantation policies.
Quantized BNNs maintain uncertainty estimation quality despite reduced precision.
problem Reduced precision in BNNs due to quantization.
method Quantized BNNs with 32-bit weights and activations compressed to 16-bit integers.
result Uniform quantization does not significantly degrade uncertainty estimation quality.
New method handles uncertainty in causal effect estimation for better decision-making.
problem Handling uncertainty in causal effect estimation, especially in high-dimensional data and covariate shift.
method Integrates uncertainty estimation into neural network methods for individual-level causal estimates.
result Uncertainty-aware methods improve decision-making by alerting when predictions are not reliable.
In most real-world settings such as recommender systems, finance, and healthcare, collecting useful information is costly and requires an active choice on the part of the decision maker. The decision-maker needs to learn simultaneously what observations to make and what actions to take. This paper incorporates the info…
Black box machine learning models are currently being used for high stakes decision-making throughout society, causing problems throughout healthcare, criminal justice, and in other domains. People have hoped that creating methods for explaining these black box models will alleviate some of these problems, but trying t…
Survey on making machine learning models more understandable.
problem Making predictions from machine learning models transparent and understandable for humans.
method Conducts a survey on explainable supervised machine learning approaches.
result Classifies explainable SML approaches and discusses future directions.
Life-expectancy is a complex outcome driven by genetic, socio-demographic, environmental and geographic factors. Increasing socio-economic and health disparities in the United States are propagating the longevity-gap, making it a cause for concern. Earlier studies have probed individual factors but an integrated pictur…
Unified framework for imputation and prediction in healthcare time series.
problem Time misalignment and data sparsity in healthcare time series.
method MAGIC (Multi-tAsk Gaussian Process for Imputation and Classification) using hierarchical multi-task Gaussian process and functional logistic regression.
result Superior predictive accuracy compared to existing methods in two healthcare applications.
Method constructs prediction intervals for time-varying individual treatment effects.
problem Accurately quantify uncertainty of individual treatment effects across multiple decision points.
method Conformal inference techniques for time-varying ITEs with weaker assumptions.
result Guaranteed lower bound for coverage dependent on data non-exchangeability.
Study finds incorporating fairness in healthcare models doesn't improve performance or net benefit.
problem Addressing health inequities in healthcare through algorithmic fairness.
method Empirical case study using models to estimate atherosclerotic cardiovascular disease risk.
result Incorporating fairness considerations into model training objective does not improve model performance or net benefit.
Much attention has been devoted recently to the development of machine learning algorithms with the goal of improving treatment policies in healthcare. Reinforcement learning (RL) is a sub-field within machine learning that is concerned with learning how to make sequences of decisions so as to optimize long-term effect…
Deep learning complements OR/MS for decision-making under uncertainty.
problem Sequential decision-making in uncertain environments.
method Integration of deep learning and OR/MS frameworks.
result Deep learning enhances adaptability and scalability in decision systems.
Estimation of individual treatment effects is commonly used as the basis for contextual decision making in fields such as healthcare, education, and economics. However, it is often sufficient for the decision maker to have estimates of upper and lower bounds on the potential outcomes of decision alternatives to assess …
Prediction models can harm patients even when accurate, leading to self-fulfilling prophecies.
problem Prediction models can lead to harmful decisions that worsen patient outcomes.
method Formal characterization of harmful prediction models and analysis of their impact.
result Well-calibrated models are ineffective for decision-making as they do not change the data distribution.
Neural Additive Models combine neural nets with interpretable models for high stakes tasks.
problem Inability to understand how neural networks make decisions.
method Combines neural nets with generalized additive models to create Neural Additive Models (NAMs).
result NAMs are more accurate than intelligible models and as accurate as state-of-the-art generalized additive models.
The paper proposes a method to calibrate healthcare AI models for reliability and interpretability.
problem Characterizing model reliability and enabling introspection of model behavior in clinical decision making.
method A calibration-driven learning method combined with interpretability techniques based on counterfactual reasoning.
result Demonstrates the effectiveness of the proposed approach using a lesion classification problem with dermoscopy images.
This tutorial reviews offline RL methods and challenges in deep learning.
problem Extracting optimal policies from large datasets without online data.
method Review of existing offline RL algorithms and potential solutions.
result Challenges and open problems in modern deep RL methods.
The paper studies causal effects of multiple treatments in healthcare databases with rare outcomes.
problem Estimating causal effects of multiple treatments in healthcare databases with rare outcomes.
method The paper designs three sets of simulations and compares the operating characteristics of three types of methods: Bayesian Additive Regression Trees (BART), regression adjustment on multivariate spline of generalized propensity scores (RAMS), and inverse probability of treatment weighting (IPTW) with multinomial logistic regression or generalized boosted models.
result BART and RAMS provide lower bias and mean squared error compared to IPTW methods.
New online method for statistical inference with matrix context in decision-making.
problem Statistical inference in decision-making with matrix context.
method Proposes a fully online procedure to conduct statistical inference with adaptive data collection, handling low-rank structure.
result Establishes asymptotic normality of debiased estimators and proves validity of confidence intervals.
Developing reliable workload predictive models can affect many aspects of clinical decision making procedure. The primary challenge in healthcare systems is handling the demand uncertainty over the time. This issue becomes more critical for the healthcare facilities that provide service for chronic disease treatment be…
The paper tackles optimal policy learning with asymmetric counterfactual utilities in healthcare decisions.
problem Learning optimal policies from observed data with asymmetric counterfactual utilities.
method The approach involves identifying and minimizing the maximum expected utility loss using statistical decision theory and solving intermediate classification problems.
result One can learn minimax loss decision rules from observed data.
MCU-Net combines U-Net and Monte Carlo Dropout for uncertainty in medical image segmentation.
problem Lack of uncertainty representation in deep learning methods for patient-centered healthcare decisions.
method MCU-Net framework using U-Net and Monte Carlo Dropout with four uncertainty metrics.
result MCU-Net maximizes automated performance and refers truly uncertain cases.
ADHAM provides interpretable survival analysis for healthcare.
problem Limited interpretability in deep learning survival models.
method Additive Deep Hazard Analysis Mixtures (ADHAM) with latent subgroup structure.
result ADHAM offers interpretable insights into exposure-outcome associations.
Bayesian Supervised Causal Clustering identifies patient subgroups for personalized decision-making.
problem Finding patient subgroups with similar characteristics for personalized decision-making.
method Bayesian Supervised Causal Clustering (BSCC) that identifies homogenous subgroups based on treatment effects.
result BSCC identifies subgroups with similar covariate profiles and treatment effects.
Study finds racial bias in pulse oximeter readings has minimal impact on ICU ventilation rates.
problem Racial disparities in pulse oximeter readings affect clinical decisions in ICU settings.
method Causal inference using path-specific effects and doubly robust estimator.
result Minimal impact of racial discrepancies on invasive ventilation rates, but more pronounced on ventilation duration.
The paper corrects bias in fluid approximation for better decision-making in stochastic optimization.
problem Bias introduced by using mean values in fluid approximation leads to suboptimal decisions.
method Identifying a decision-corrected point estimate that yields optimal decisions.
result A corrected point estimate exists under certain conditions and can be computed algorithmically.
Bayesian method estimates dynamics from near-optimal trajectories.
problem Estimating dynamics from near-optimal expert trajectories in reinforcement learning.
method Constraint-based Bayesian approach integrating expert near-optimality.
result Significant improvements in decision-making and transfer success.
LUQ-Learning adapts Q-learning for healthcare decisions considering patient preferences.
problem Optimizing treatment decisions for multivariate outcomes based on individual preferences.
method Latent Utility Q-Learning (LUQ-Learning) framework that adapts Q-learning for composite outcomes.
result LUQ-Learning achieves highly competitive performance compared to alternative methods in simulations.
A new method synthesizes expressions from characteristics using GAN for healthcare.
problem Synthesizing expressions from given characteristics in high-dimensional space.
method Generative Adversarial Network (GAN) based selective ensemble learning.
result The proposed SE-CTES method effectively handles deterministic and stochastic patterns.