Survey on securing ML for healthcare, addressing privacy and robustness issues.
problem Security and robustness challenges in healthcare ML/DL applications.
method Overview of security and privacy methods for ML in healthcare.
result Discussion of current research challenges and future directions.
Big data analytics improves healthcare through early detection and quality life.
problem Limited access to healthcare data hinders evidence-based decision-making.
method Analysis of healthcare data using various tools and techniques.
result Big data analytics enhances healthcare quality and patient outcomes.
The paper proposes a method to calibrate healthcare AI models for reliability and interpretability.
problem Characterizing model reliability and enabling introspection of model behavior in clinical decision making.
method A calibration-driven learning method combined with interpretability techniques based on counterfactual reasoning.
result Demonstrates the effectiveness of the proposed approach using a lesion classification problem with dermoscopy images.
The study diagnoses fairness issues in healthcare models under distribution shifts.
problem Understanding and diagnosing fairness changes in machine learning models under distribution shifts in healthcare.
method Causal framing and conditional independence tests to characterize distribution shifts.
result Knowledge of distribution shifts helps diagnose fairness transfer failures, including complex cases.
Study identifies key aspects of explainable ML for clinical trust.
problem Lack of concrete definitions for usable explanations in clinical settings.
method Surveyed clinicians from two specialties to understand their needs for explainability.
result Characterized specific aspects of explainability that improve trust in ML models.
Natural language processing predicts ICU readmissions with 74.8% accuracy.
problem Early detection of ICU readmissions to improve patient outcomes and reduce costs.
method Natural language processing of discharge summaries, machine learning classifiers, UMLS standardization.
result Best configuration achieved an AUC of 0.748 for predicting ICU readmissions.
Background: Predictive modeling is a key component of solutions to many healthcare problems. Among all predictive modeling approaches, machine learning methods often achieve the highest prediction accuracy, but suffer from a long-standing open problem precluding their widespread use in healthcare. Most machine learning…
Study improves mortality prediction in hospital patients using comprehensive feature engineering.
problem Accurate prediction of all-cause in-hospital mortality in healthcare.
method Comprehensive feature engineering approach using vital signs, laboratory results, and demographic data.
result Random Forest model achieved highest performance with AUC of 0.94, significantly outperforming other models.
LogGENE uses log-cosh loss for deep learning in gene expression datasets, improving accuracy and interpretability.
problem Mining large gene expression datasets for reliable deep learning predictions.
method Develops a smooth alternative to check loss (log-cosh) for quantile regression in gene expression datasets.
result Achieves state-of-the-art performance in accuracy and provides robust uncertainty estimates.
This paper reviews methods to improve AI explainability in finance.
problem Lack of explainability in AI models, especially in finance.
method Categorizes methods to improve explainability of deep learning models.
result Provides a comparative survey of methods to enhance AI explainability.
TRACER improves interpretability in high stakes analytics.
problem Interpreting complex models in high stakes applications.
method TRACER framework with TITV model for healthcare analytics.
result TRACER facilitates both accurate and interpretable analytics.
To date, the instability of prognostic predictors in a sparse high dimensional model, which hinders their clinical adoption, has received little attention. Stable prediction is often overlooked in favour of performance. Yet, stability prevails as key when adopting models in critical areas as healthcare. Our study propo…
Develops causal framework for fair survival analysis in healthcare.
problem Fairness in survival analysis for high-stakes domains like healthcare.
method Causal framework using graphical models, conditional survival function, and Causal Reduction Theorem.
result Decomposes disparities in survival into direct, indirect, and spurious pathways.
RETAIN model improves glucose forecasting for diabetics, offering both accuracy and interpretability.
problem Inability of deep learning models to interpret their predictions in healthcare.
method Two-level attention mechanism in a recurrent neural network (RETAIN) architecture.
result RETAIN model achieves comparable accuracy to LSTM and FCN models while being highly interpretable.
We partner with a leading European healthcare provider and design a mechanism to match patients with family doctors in primary care. We define the matchmaking process for several distinct use cases given different levels of available information about patients. Then, we adopt a hybrid recommender system to present each…
The hypothesis that computational models can be reliable enough to be adopted in prognosis and patient care is revolutionizing healthcare. Deep learning, in particular, has been a game changer in building predictive models, thus leading to community-wide data curation efforts. However, due to inherent variabilities in …
GANs help create realistic synthetic health data, boosting medical research.
problem Challenges in creating realistic synthetic health data due to private patient data.
method Generative Adversarial Networks (GANs) to learn and produce synthetic health data.
result GANs can produce realistic synthetic health data, overcoming challenges in OHD.
Probabilistic ML improves healthcare data analysis.
problem Insufficient understanding and incomplete data in healthcare.
method Examination of probabilistic machine learning models for healthcare challenges.
result Probabilistic models enhance healthcare data analysis and model building.
A statistical description and model of individual healthcare expenditures in the US has been developed for measuring value in healthcare. We find evidence that healthcare expenditures are quantifiable as an infusion-diffusion process, which can be thought of intuitively as a steady change in the intensity of treatment …
Clinical data for ambulatory care, which accounts for 90% of the nations healthcare spending, is characterized by relatively small sample sizes of longitudinal data, unequal spacing between visits for each patient, with unequal numbers of data points collected across patients. While deep learning has become state-of-th…
Study identifies what healthcare tasks can and should be automated.
problem Undesired consequences of automation in healthcare.
method Quantitative analysis using machine learning models trained on practitioner and expert ratings.
result Developed an analytical tool (Automatability-Desirability Matrix) for policymakers and leaders.
MPVAA learns holistic patient representations from mixed healthcare data.
problem Learning personalized patient representations from heterogeneous healthcare data.
method Mixed Pooling Multi-View Attention Autoencoder (MPVAA) that integrates non-linear relationships among multiple data modalities.
result MPVAA generates more effective patient representations than state-of-the-art methods.
Health care is one of the most exciting frontiers in data mining and machine learning. Successful adoption of electronic health records (EHRs) created an explosion in digital clinical data available for analysis, but progress in machine learning for healthcare research has been difficult to measure because of the absen…
The paper tackles policy learning in dynamic environments using causal methods.
problem Existing reinforcement learning algorithms assume static mechanisms, but real-world systems often have changing mechanisms.
method The paper introduces multi-environment contextual bandits and policy invariance to handle environmental shifts.
result An optimal invariant policy is guaranteed to generalize across environments under suitable assumptions.
One of the main issues affecting the Italian NHS is the healthcare deficit: according to current agreements between the Italian State and its Regions, public funding of regional NHS is now limited to the amount of regional deficit and is subject to previous assessment of strict adherence to constraint on regional healt…
This paper solves the problem of optimal dynamic consumption, investment, and healthcare spending with isoelastic utility, when natural mortality grows exponentially to reflect Gompertz' law and investment opportunities are constant. Healthcare slows the natural growth of mortality, indirectly increasing utility from c…
Machine Learning (ML) applications on healthcare can have a great impact on people's lives helping deliver better and timely treatment to those in need. At the same time, medical data is usually big and sparse requiring important computational resources. Although it might not be a problem for wide-adoption of ML tools …
Study optimal healthcare spending under Epstein-Zin preferences for longevity.
problem Optimizing healthcare spending to extend longevity under Epstein-Zin preferences.
method Formulated Epstein-Zin utilities over a controllable random horizon using backward stochastic differential equations and HJB equations.
result Calibrated model accurately reflects actual mortality data and compares healthcare efficacy between countries.
Study improves conformal prediction for EEG classification in healthcare, enhancing coverage.
problem Uncertainty quantification in clinical predictions, especially in distribution-shifted settings.
method Personalized calibration strategies to improve coverage of prediction sets.
result Coverage improved by over 20 percentage points with comparable prediction set sizes.
A recommendation framework helps users choose healthcare interventions.
problem Choice overload in online healthcare communities.
method Multi-Armed Bandit (MAB) approach with innovative model components.
result Our recommendation design outperforms state-of-the-art systems.
RL algorithms with medical integration improve personalized treatment recommendations.
problem Developing effective personalized treatment strategies for chronic diseases.
method Integrating medical knowledge into RL algorithms for DTR.
result Enhanced treatment recommendations with increased confidence.
Interpretability of ML models improves healthcare decisions.
problem Ensuring machine learning models are understandable for healthcare users.
method Classifying interpretability into local and global approaches, and model-specific vs. model-agnostic methods.
result Examples of practical interpretability in healthcare, including prediction and treatment optimization.
survex explains machine learning survival models, improving model transparency.
problem Lack of tools to explain machine learning survival models.
method Introduces survex R package using explainable AI techniques.
result Improves model reliability and detects biases in survival models.
LLMs excel at summarizing and repairing complex models without needing full models.
problem Understanding and repairing complex models like GAMs.
method Hierarchical reasoning and extensive background knowledge.
result LLMs can detect anomalies, describe reasons, and suggest repairs.
State-of-the-art clustering algorithms use heuristics to partition the feature space and provide little insight into the rationale for cluster membership, limiting their interpretability. In healthcare applications, the latter poses a barrier to the adoption of these methods since medical researchers are required to pr…
DAISYnt evaluates synthetic data quality and privacy in regulated domains.
problem Balancing data quality and privacy in regulated domains.
method Developed a suite of advanced tests (DAISYnt) to evaluate synthetic data quality and privacy.
result DAISYnt sets a de facto standard for synthetic data evaluation in regulated domains.
LMM predicts healthcare costs and risks with improved accuracy.
problem Wasteful healthcare spending and inefficiencies in risk prediction.
method Generative pre-trained transformer trained on patient event sequences.
result Improves cost prediction by 14.1% and chronic conditions prediction by 1.9%.
Study improves healthcare time series imputation by considering structured missingness.
problem Structured missingness in clinical data impacts time series imputation models.
method Analysis of different masking strategies on imputation methods using PhysioNet Challenge 2012 dataset.
result Masking choices significantly affect imputation accuracy and clinical prediction.
Paper presents a privacy-preserving algorithm for estimating peer effects using the Ising model.
problem Privacy concerns in estimating peer effects using network data.
method Developed a (ε,δ)-differentially private algorithm using Ising model. result Established regret bounds and validated performance on synthetic and real-world networks.
Unified framework for imputation and prediction in healthcare time series.
problem Time misalignment and data sparsity in healthcare time series.
method MAGIC (Multi-tAsk Gaussian Process for Imputation and Classification) using hierarchical multi-task Gaussian process and functional logistic regression.
result Superior predictive accuracy compared to existing methods in two healthcare applications.
Study analyzes factors influencing healthcare providers' engagement with SMS campaigns.
problem Understanding what drives healthcare providers to engage with SMS campaigns.
method Used logistic regression, random forest, and neural network models to analyze data.
result Identified key factors influencing engagement with SMS campaigns.
MCRAGE generates synthetic data to balance healthcare datasets.
problem Imbalanced datasets in healthcare lead to biased model performance for minority groups.
method Generative modeling to create synthetic data for underrepresented classes.
result MCRAGE improves model performance on minority groups.
Modeling disease progression in healthcare administrative databases is complicated by the fact that patients are observed only at irregular intervals when they seek healthcare services. In a longitudinal cohort of 76,888 patients with chronic obstructive pulmonary disease (COPD), we used a continuous-time hidden Markov…
Research predicts healthcare index movements using historical OHLC data.
problem Predicting the directional movement of healthcare indices based on historical data.
method Supervised classification task with a one-step-ahead rolling window, using a diverse feature set including OHLC ratios.
result Robust predictive performance with accuracy exceeding 0.8 and Matthews correlation coefficients above 0.6, highlighting the importance of nowcasting features.
Unsupervised model detects healthcare fraud from patient visit data.
problem Detecting fraudulent healthcare bills from patient visit data.
method Uses LSTM and seq2seq models for anomaly detection, normalizes scores with EDF.
result Improves anomaly detection for high class imbalance problems.
Proposes a method to improve rare event prediction in healthcare.
problem Rare event classification in healthcare with low prevalence labels.
method Variational disentanglement approach to semi-parametric learning.
result Outperforms existing alternatives in mortality prediction on COVID-19 cohort.
VHGM-MAE generates synthetic humans from healthcare data.
problem Handling high-dimensional, sparse healthcare data with missing values.
method Masked autoencoder (MAE) tailored for healthcare data, addressing heterogeneity, missingness, and high-dimensionality.
result VHGM-MAE outperforms existing methods in missing value imputation and synthetic data generation.
Isthmus platform simplifies ML/AI integration in healthcare.
problem Challenges in deploying ML models in healthcare due to data quality, regulatory, and security issues.
method Turnkey, cloud-based platform addressing data quality, clinical relevance, and regulatory compliance.
result Reduces time to market for operationalizing ML/AI in healthcare.