Improves disease progression prediction using auxiliary surrogate labels and health markers.
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Predicts clinical events using a landmark approach with machine learning for large biomarker histories.
Study user engagement in mobile health apps for health workers in resource-poor settings.
The paper proposes a method to assess surrogate heterogeneity in non-randomized data.
The method integrates survival constraints into NMF for identifying survival-associated gene clusters.
Activity and motion analysis has the potential to be used as a diagnostic tool for mental disorders. However, to-date, little work has been performed in turning stratification measures of activity into useful symptom markers. The research presented in this thesis has focused on the identification of objective activity …
The introduction of data analytics into medicine has changed the nature of patient treatment. In this, patients are asked to disclose personal information such as genetic markers, lifestyle habits, and clinical history. This data is then used by statistical models to predict personalized treatments. However, due to pri…
Novel method identifies proteomic risk markers for Alzheimer disease.
AR app visualizes Quranic Surah al-Fil for Islamic education.
Microbial clades modeling is a challenging problem in biology based on microarray genome sequences, especially in new species gene isolates discovery and category. Marker family genome sequences play important roles in describing specific microbial clades within species, a framework of support vector machine (SVM) base…
MarkerMap selects key genes for cell type analysis in single-cell RNA-seq.
Bayesian model enhances phenotype discovery in asthma EHRs.
This paper introduces the factorial marked temporal point process model and presents efficient learning methods. In conventional (multi-dimensional) marked temporal point process models, event is often encoded by a single discrete variable i.e. a marker. In this paper, we describe the factorial marked point processes w…
We target modeling latent dynamics in high-dimension marked event sequences without any prior knowledge about marker relations. Such problem has been rarely studied by previous works which would have fundamental difficulty to handle the arisen challenges: 1) the high-dimensional markers and unknown relation network amo…
CNMs detect tipping points in complex systems using causal network markers.
The diagnosis of Alzheimer's disease (AD) in routine clinical practice is most commonly based on subjective clinical interpretations. Quantitative electroencephalography (QEEG) measures have been shown to reflect neurodegenerative processes in AD and might qualify as affordable and thereby widely available markers to f…
Preterm birth is the most common cause of neonatal death. Current diagnostic methods that assess the risk of preterm birth involve the collection of maternal characteristics and transvaginal ultrasound imaging conducted in the first and second trimester of pregnancy. Analysis of the ultrasound data is based on visual i…
fiBAG integrates multiplatform genomic data to identify disease markers.
With the arrival of the big data era, more and more data are becoming readily available in various real-world applications and those data are usually highly heterogeneous. Taking computational medicine as an example, we have both Electronic Health Records (EHR) and medical images for each patient. For complicated disea…
Stress research is a rapidly emerging area in thefield of electroencephalography (EEG) based signal processing.The use of EEG as an objective measure for cost effective andpersonalized stress management becomes important in particularsituations such as the non-availability of mental health facilities.In this study, lon…
Quantifying behavior is crucial for many applications in neuroscience. Videography provides easy methods for the observation and recording of animal behavior in diverse settings, yet extracting particular aspects of a behavior for further analysis can be highly time consuming. In motor control studies, humans or other …
For precision medicine and personalized treatment, we need to identify predictive markers of disease. We focus on Alzheimer's disease (AD), where magnetic resonance imaging scans provide information about the disease status. By combining imaging with genome sequencing, we aim at identifying rare genetic markers associa…
We describe a method that infers whether statistical dependences between two observed variables X and Y are due to a "direct" causal link or only due to a connecting causal path that contains an unobserved variable of low complexity, e.g., a binary variable. This problem is motivated by statistical genetics. Given a ge…
Study uses DNM theory to detect early warning signals of market instability.
Standard models assign disease progression to discrete categories or stages based on well-characterized clinical markers. However, such a system is potentially at odds with our understanding of the underlying biology, which in highly complex systems may support a (near-)continuous evolution of disease from inception to…
The paper proposes a method to integrate prior information into penalized regression.
Proposes a two-stage method for estimating heterogeneous treatment effects using gradient boosting trees.
The paper analyzes the observability of relative pose estimation using dual quaternions.
Many complex disease syndromes such as asthma consist of a large number of highly related, rather than independent, clinical phenotypes, raising a new technical challenge in identifying genetic variations associated simultaneously with correlated traits. In this study, we propose a new statistical framework called grap…
Feature selection predicts immune state changes in RA mouse model.
New method classifies reticulocytes from red blood cells without labels.
Neural network training entails heavy computation with obvious bottlenecks. The Compute Unified Device Architecture (CUDA) programming model allows us to accelerate computation by passing the processing workload from the CPU to the graphics processing unit (GPU). In this paper, we leveraged the power of Nvidia GPUs to …
As societies around the world are ageing, the number of Alzheimer's disease (AD) patients is rapidly increasing. To date, no low-cost, non-invasive biomarkers have been established to advance the objectivization of AD diagnosis and progression assessment. Here, we utilize Bayesian neural networks to develop a multivari…
AR app enhances young children's understanding of Wudhu.
Repository tackles fake health news in cancer research.
Study finds macroeconomic indicators predict health workforce and infrastructure measures.
Study uses machine learning to predict future health from various health data types.
In this paper we extend the market-making models with inventory constraints of Avellaneda and Stoikov ("High-frequency trading in a limit-order book", Quantitative Finance Vol.8 No.3 2008) and Gueant, Lehalle and Fernandez-Tapia ("Dealing with inventory risk", Preprint 2011) to the case of a rather general class of mid…
New algorithm forecasts health indicators for better equipment lifespan prediction.
LHIEM model predicts health, income, and employment over years.
Automatically assesses the quality of online health articles.
One primary task of population health analysis is the identification of risk factors that, for some subpopulation, have a significant association with some health condition. Examples include finding lifestyle factors associated with chronic diseases and finding genetic mutations associated with diseases in precision he…
Let R be an o-minimal expansion of the real field. We introduce a class of Hausdorff limits, the T-infinity limits over R, that do not in general fall under the scope of Marker and Steinhorn's definability-of-types theorem. We prove that if R admits analytic cell decomposition, then every T-infinity limit over R is def…
Mobile apps and machine learning improve malaria prevention and treatment.
Flow cytometry is often used to characterize the malignant cells in leukemia and lymphoma patients, traced to the level of the individual cell. Typically, flow cytometric data analysis is performed through a series of 2-dimensional projections onto the axes of the data set. Through the years, clinicians have determined…
Study assesses health plan risk measures for Solvency Capital Requirement.
Although there are millions of transgender people in the world, a lack of information exists about their health issues. This issue has consequences for the medical field, which only has a nascent understanding of how to identify and meet this population's health-related needs. Social media sites like Twitter provide ne…
Deep neural network predicts health costs better than traditional models.