Genetic algorithms have been widely used in many practical optimization problems. Inspired by natural selection, operators, including mutation, crossover and selection, provide effective heuristics for search and black-box optimization. However, they have not been shown useful for deep reinforcement learning, possibly …
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Optimizing a neural network's performance is a tedious and time taking process, this iterative process does not have any defined solution which can work for all the problems. Optimization can be roughly categorized into - Architecture and Hyperparameter optimization. Many algorithms have been devised to address this pr…
Efficiently infers graph edges from genetic similarity data in landscape genetics.
Genetic algorithms optimize neural networks for cosmological data analysis.
BOSS optimizes string inputs using string kernels and genetic algorithms.
Gradient GA uses gradient information to improve molecular design.
GEGL uses genetic experts to improve deep learning for molecular design.
Deep neural network learning can be formulated as a non-convex optimization problem. Existing optimization algorithms, e.g., Adam, can learn the models fast, but may get stuck in local optima easily. In this paper, we introduce a novel optimization algorithm, namely GADAM (Genetic-Evolutionary Adam). GADAM learns deep …
We introduce the Genetic-Gated Networks (G2Ns), simple neural networks that combine a gate vector composed of binary genetic genes in the hidden layer(s) of networks. Our method can take both advantages of gradient-free optimization and gradient-based optimization methods, of which the former is effective for problems …
In this paper, we propose a framework for automatic classification of patients from multimodal genetic and brain imaging data by optimally combining them. Additive models with unadapted penalties (such as the classical group lasso penalty or -multiple kernel learning) treat all modalities in the same manner and ca…
Genetic Algorithm improves Nelson-Siegel-Svensson model calibration for interest rates.
Hedging in the presence of transaction costs leads to complex optimization problems. These problems typically lack closed-form solutions, and their implementation relies on numerical methods that provide hedging strategies for specific parameter values. In this paper we use a genetic programming algorithm to derive exp…
Improved genetic algorithm optimizes SVR for robust long-term stock index forecasting.
We analyze the accuracy of traffic simulations metamodels based on neural networks and gradient boosting models (LightGBM), applied to traffic optimization as fitness functions of genetic algorithms. Our metamodels approximate outcomes of traffic simulations (the total time of waiting on a red signal) taking as an inpu…
BOAT optimizes multiple antibody properties efficiently.
Networks of coupled dynamical systems provide a powerful way to model systems with enormously complex dynamics, such as the human brain. Control of synchronization in such networked systems has far reaching applications in many domains, including engineering and medicine. In this paper, we formulate the synchronization…
Technical analysis is used to discover investment opportunities. To test this hypothesis we propose an hybrid system using machine learning techniques together with genetic algorithms. Using technical analysis there are more ways to represent a currency exchange time series than the ones it is possible to test computat…
Proposes Genetic Thompson Sampling for multi-armed bandits, improving performance in nonstationary settings.
Genome-wide association studies (GWAS) have achieved great success in the genetic study of Alzheimer's disease (AD). Collaborative imaging genetics studies across different research institutions show the effectiveness of detecting genetic risk factors. However, the high dimensionality of GWAS data poses significant cha…
BoGA combines evolutionary search with Bayesian optimization for efficient protein design.
ENN method uses expectile regression for genetic data analysis of complex diseases.
Fast and cheaper next generation sequencing technologies will generate unprecedentedly massive and highly-dimensional genomic and epigenomic variation data. In the near future, a routine part of medical record will include the sequenced genomes. A fundamental question is how to efficiently extract genomic and epigenomi…
Semi-supervised GAN creates synthetic genetic data for disease prediction.
In this paper we propose the use of quantum genetic algorithm to optimize the support vector machine (SVM) for human action recognition. The Microsoft Kinect sensor can be used for skeleton tracking, which provides the joints' position data. However, how to extract the motion features for representing the dynamics of a…
Gradient-based methods are often used for policy optimization in deep reinforcement learning, despite being vulnerable to local optima and saddle points. Although gradient-free methods (e.g., genetic algorithms or evolution strategies) help mitigate these issues, poor initialization and local optima are still concerns …
Study improves chiral photonic metasurface design using neural networks and genetic algorithms.
Optimizes group testing for COVID-19 to reduce test numbers.
GeneCAI optimizes DNN compression hyper-parameters for mobile devices.
In this paper, we compare the three most popular algorithms for hyperparameter optimization (Grid Search, Random Search, and Genetic Algorithm) and attempt to use them for neural architecture search (NAS). We use these algorithms for building a convolutional neural network (search architecture). Experimental results on…
AI learns market manipulation through simulation, suggesting regulation.
Discovering causal genetic variants from large genetic association studies poses many difficult challenges. Assessing which genetic markers are involved in determining trait status is a computationally demanding task, especially in the presence of gene-gene interactions. A non-parametric Bayesian approach in the form o…
Metaheuristics optimize portfolios with pre-assignment and margin trading for better risk-adjusted returns.
Genome-wide association studies (GWAS) have emerged as a rich source of genetic clues into disease biology, and they have revealed strong genetic correlations among many diseases and traits. Some of these genetic correlations may reflect causal relationships. We developed a method to quantify causal relationships betwe…
Deep learning and genetic algorithms speed up cosmological Bayesian inference.
Novel tests for genetic independence in high-dimensional data.
For precision medicine and personalized treatment, we need to identify predictive markers of disease. We focus on Alzheimer's disease (AD), where magnetic resonance imaging scans provide information about the disease status. By combining imaging with genome sequencing, we aim at identifying rare genetic markers associa…
Deep models improve GWAS by identifying genetic interactions.
New computational methods improve clustering of objects.
Paper proposes a hybrid AI method to optimize pandemic actions.
We introduce GeNet, a method for shotgun metagenomic classification from raw DNA sequences that exploits the known hierarchical structure between labels for training. We provide a comparison with state-of-the-art methods Kraken and Centrifuge on datasets obtained from several sequencing technologies, in which dataset s…
New method uses DNN for genetic variant identification, controlling randomness and improving interpretability.
Improved genetic programming by optimizing mutation operators for continuous program search.
Multi-task learning uses auxiliary data or knowledge from relevant tasks to facilitate the learning in a new task. Multi-task optimization applies multi-task learning to optimization to study how to effectively and efficiently tackle multiple optimization problems simultaneously. Evolutionary multi-tasking, or multi-fa…
Genetic sequence data are well described by hidden Markov models (HMMs) in which latent states correspond to clusters of similar mutation patterns. Theory from statistical genetics suggests that these HMMs are nonhomogeneous (their transition probabilities vary along the chromosome) and have large support for self tran…
Paper uses AI to predict stock market volatility with neural networks and genetic algorithms.
In plant and animal breeding studies a distinction is made between the genetic value (additive + epistatic genetic effects) and the breeding value (additive genetic effects) of an individual since it is expected that some of the epistatic genetic effects will be lost due to recombination. In this paper, we argue that t…
As the complexity of neural network models has grown, it has become increasingly important to optimize their design automatically through metalearning. Methods for discovering hyperparameters, topologies, and learning rate schedules have lead to significant increases in performance. This paper shows that loss functions…
Design-by-Morphing creates radical airfoil designs without geometric constraints.