Research
On-device research index

arXiv research

A locally-built, LLM-digested index of recent arXiv papers in quant finance, geometry/topology, and statistical ML — keyword search served straight from SQLite on this machine.

168,742 papers · 148 categories

Trend · papers per month

481216 · Jul 202019922001200920172026
48 results for epigenetic aging

Novel U-learning method for predicting continuous outcomes from high-dimensional data.

problem Challenges in making valid inferences on predictions from high-dimensional inputs.
method U-learning via combinatory multi-subsampling for ensemble predictions and confidence intervals.
result Valid inferences on predictions from Lasso and neural networks.

Proposes spBART for risk prediction using epigenetic signatures and covariates.

problem Complex high-dimensional epigenetic data and low-dimensional covariates for risk prediction.
method Semi-parametric Bayesian Additive Regression Trees (spBART) with cross-validation for variable selection.
result Achieves strong out-of-sample discrimination (AUC = 0.96) in held-out validation set.

With the wealth of high-throughput sequencing data generated by recent large-scale consortia, predictive gene expression modelling has become an important tool for integrative analysis of transcriptomic and epigenetic data. However, sequencing data-sets are characteristically large, and previously modelling frameworks …

2015-07-21abs ↗pdf ↗

In this paper we propose network methodology to infer prognostic cancer biomarkers based on the epigenetic pattern DNA methylation. Epigenetic processes such as DNA methylation reflect environmental risk factors, and are increasingly recognised for their fundamental role in diseases such as cancer. DNA methylation is a…

2015-06-17abs ↗pdf ↗

The research reported in this paper identifies the epigenetic biomarker (methylation beta pattern) of breast cancer. Many cancers are triggered by abnormal gene expression levels caused by aberrant methylation of CpG sites in the DNA. In order to develop early diagnostics of cancer-causing methylations and to develop a…

2019-10-12abs ↗pdf ↗

Method converts age labels into distributions to improve speaker age estimation.

problem Label ambiguity in age labels makes precise speaker age estimation challenging.
method Converts age labels into label distributions and uses label distribution learning.
result Our method outperforms baseline methods by reducing MAE by 10% on a real-world dataset.

We solve a lifecycle model in which the consumer's chronological age does not move in lockstep with calendar time. Instead, biological age increases at a stochastic non-linear rate in time like a broken clock that might occasionally move backwards. In other words, biological age could actually decline. Our paper is ins…

2018-11-25abs ↗pdf ↗

The paper uses AI to analyze ECG data, revealing age-related changes and identifying key features.

problem Investigating age-related changes in ECG data to distinguish healthy from disease-related changes.
method Employed deep-learning and tree-based models on raw ECG signals and features from a diverse age group.
result Identified age-related declines in breathing rates and high SDANN values in elderly individuals.

A new FL algorithm reduces communication overhead by selectively updating model parameters.

problem Data heterogeneity and communication overhead in federated learning.
method Uses age of information metric to selectively update model parameters and group clients with similar data.
result Our method can expedite training and surpass other communication-efficient strategies in efficiency.

AGE improves graph embedding by smoothing features and iteratively enhancing node embeddings.

problem Challenges in attributed graph embedding, especially in preserving optimal low-pass characteristics and robustness.
method AGE, a novel framework combining Laplacian smoothing and adaptive encoding, addresses these issues.
result AGE consistently outperforms state-of-the-art methods on node clustering and link prediction tasks.

Study reveals that cryptocurrency price variations follow power-law distributions, influenced by age and market capitalization.

problem Understanding the statistical properties of cryptocurrencies, especially their price variations.
method Comprehensive investigation of over 7000 digital currencies, analyzing their price returns over time.
result Cryptocurrency price returns follow power-law distributions, with age and market capitalization influencing these distributions.

The paper proposes a method to integrate prior information into penalized regression.

problem Improving predictive performance in high-dimensional tasks with prior information.
method Integrating multiple sources of prior information into penalized regression.
result The method improves predictive performance, as shown by simulations and applications.

Machine learning models predict brain age with systematic bias, corrected in this study.

problem Systematic bias in machine learning regression models for brain age prediction.
method General constrained optimization approach to correct bias.
result Our method effectively eliminates the bias from brain age predictions.

Proposes a new model for mortality forecasting considering age groups and cohort effects.

problem Longevity risk due to ageing population.
method Mixed-effects time-series approach with age groups dependency and random cohort effects.
result Remarkable improvements in forecast accuracy compared to the CBD model.

Optimal annuitization strategy depends on age, labor income, and mortality risk.

problem Maximizing utility from consumption and labor income under age-dependent mortality.
method Dynamic programming approach to derive closed-form solutions.
result Post-retirement labor income acts as a substitute for annuitization.

This paper solves the problem of optimal dynamic consumption, investment, and healthcare spending with isoelastic utility, when natural mortality grows exponentially to reflect Gompertz' law and investment opportunities are constant. Healthcare slows the natural growth of mortality, indirectly increasing utility from c…

2019-01-02abs ↗pdf ↗

VNNs transfer well across datasets for brain age prediction using cortical thickness features.

problem Predicting brain age using anatomical features.
method Transferability of coVariance neural networks (VNNs) in brain age prediction.
result VNNs can assign anatomical interpretability to elevated brain age gap in AD.

4-dim intrinsic (material) Riemannian metric GG of the material 4-D space-time continuum PP is utilized as the characteristic of the aging processes developing in the material. Manifested through variation of basic material characteristics such as density, moduli of elasticity, yield stress, strength, and toughness.,…

2006-04-16abs ↗pdf ↗

The paper uses distance correlation for brain connectivity and a novel multi-task learning model for age prediction.

problem Estimating age-related gender differences in brain functional connectivity.
method Estimates functional connectivity using distance correlation and proposes a non-convex multi-task learning model.
result The proposed non-convex multi-task learning model outperforms other models in age prediction and gender-specific connectivity.

In the age of data driven solution, the customer demographic attributes, such as gender and age, play a core role that may enable companies to enhance the offers of their services and target the right customer in the right time and place. In the marketing campaign, the companies want to target the real user of the GSM …

2019-02-20abs ↗pdf ↗