ELMV uses ensemble learning to handle missing values in EHR data.
problem Significant missing values in EHR data cause bias and unreliable conclusions.
method ELMV constructs multiple subsets with lower missing rates and uses a support set for ensemble learning.
result ELMV outperforms conventional methods in critical feature identification and outcome prediction.
In this short paper, the Electre Tri-Machine Learning Method, generally used to solve ordinal classification problems, is proposed for solving the Record Linkage problem. Preliminary experimental results show that, using the Electre Tri method, high accuracy can be achieved and more than 99% of the matches and nonmatch…
Framework identifies comorbidities for frequent ED and inpatient visits.
problem Reducing resource usage and costs in frequent patients.
method Developed MSAR algorithm to identify comorbidities.
result MSAR identifies conditions most associated with reoccurring ED and inpatient visits.
An electrocardiogram (EKG) is a common, non-invasive test that measures the electrical activity of a patient's heart. EKGs contain useful diagnostic information about patient health that may be absent from other electronic health record (EHR) data. As multi-dimensional waveforms, they could be modeled using generic mac…
Machine learning constructs problem-based medical records from electronic health records.
problem Difficulty in finding relevant medical information for clinical questions.
method Knowledge base completion using machine learning on electronic health records.
result Automatic construction of problem-based groupings of medications, procedures, and lab tests.
Bayesian model predicts patient survival from sparse EHR data.
problem Analyzing EHR data with few samples and diverse information.
method Nonparametric probabilistic model using Bayesian trees.
result Improved survival trajectory predictions on patient data.
Accurate real-time monitoring systems of influenza outbreaks help public health officials make informed decisions that may help save lives. We show that information extracted from cloud-based electronic health records databases, in combination with machine learning techniques and historical epidemiological information,…
This paper presents an example of how demographical characteristics of patients influence their susceptibility to certain medical conditions. In this paper, we investigate the association of health conditions to age of patients in a heterogeneous population. We show that besides the symptoms a patients is having, the a…
XLabel tool reduces medical experts' workload by 40% and explains its decisions.
problem Efficiently labeling large electronic health records.
method Visual-interactive tool using Explainable Boosting Machine (EBM) for classification and explanation.
result EBM achieves high accuracy and explainability, even with mislabeled data.
Deep neural network predicts health costs better than traditional models.
problem Accurate prediction of healthcare costs for optimal cost management.
method Developed a deep neural network to predict future health care costs from health insurance claims records.
result Deep neural network outperformed ridge regression and Morbi-RSA models in cost prediction.
Deep learning predicts drug prescriptions across global health records.
problem Predicting drug prescriptions in chronic disease patients.
method Adaptive cross-global attention graph kernel network with support vector machine.
result Model outperforms current methods in accuracy and interpretability.
Language models improve clinical prediction models using EHR data.
problem Limited patient data for training clinical prediction models.
method Using patient representation schemes from natural language processing.
result 3.5% mean improvement in AUROC on five prediction tasks.
AI predicts medical specialty diagnostic choices from EHR records.
problem Predicting timely medical specialty diagnostic workups for patients.
method Ensemble of feed-forward neural networks trained on EHR data.
result Significantly higher accuracy compared to traditional checklists.
Develops a method to denoise and analyze wearable ECGs.
problem Noisy ECGs from wearable devices.
method Statistical model, beat-to-beat representation, factor analysis.
result Upper bound on performance quantified and compared.
Paper improves communication in decentralized federated learning for EHRs.
problem Efficiently learn from large, decentralized EHR databases.
method Fully decentralized federated learning with iterative local updates and reduced communication rounds.
result Significant reduction in communication rounds without compromising solution optimality.
Personalized predictive medicine necessitates the modeling of patient illness and care processes, which inherently have long-term temporal dependencies. Healthcare observations, recorded in electronic medical records, are episodic and irregular in time. We introduce DeepCare, an end-to-end deep dynamic neural network t…
Managing patients with chronic diseases is a major and growing healthcare challenge in several countries. A chronic condition, such as diabetes, is an illness that lasts a long time and does not go away, and often leads to the patient's health gradually getting worse. While recent works involve raw electronic health re…
Proposes a new model for EHR data using time-dependent Gaussian processes.
problem Joint modeling of multiple clinical variables over time.
method Multivariate nonstationary Gaussian processes with time-varying parameters and posterior inference via HMC.
result The proposed model outperforms stationary models and reveals latent correlations predictive of patient risk.
New method for sensing non-planar surfaces using ERT.
problem Limited computational techniques for planar surfaces in ERT-based sensing skins.
method Generalized ERT to non-planar surfaces using Riemannian geometry.
result Feasibility and applicability of ERT-based sensing skins for non-planar geometries demonstrated.
Electronic health records (EHR) are rich heterogeneous collection of patient health information, whose broad adoption provides great opportunities for systematic health data mining. However, heterogeneous EHR data types and biased ascertainment impose computational challenges. Here, we present mixEHR, an unsupervised g…
ME2Vec learns medical entity vectors from EHR data.
problem Learning structured information from EHR data.
method Graph-based medical entity embedding using diverse graph embedding techniques.
result ME2Vec outperforms baselines in disease diagnosis prediction.
The paper presents a systematic review of state-of-the-art approaches to identify patient cohorts using electronic health records. It gives a comprehensive overview of the most commonly de-tected phenotypes and its underlying data sets. Special attention is given to preprocessing of in-put data and the different modeli…
This study evaluates a health knowledge graph for robustness in EHRs.
problem Evaluate robustness of a health knowledge graph in EHRs.
method Analyze sample size, unmeasured confounders, and non-linear functions.
result Identify sample size and unmeasured confounders as major sources of error.
Recordings of electrical brain activity carry information about a person's cognitive health. For recording EEG signals, a very common setting is for a subject to be at rest with its eyes closed. Analysis of these recordings often involve a dimensionality reduction step in which electrodes are grouped into 10 or more re…
The past decade has seen an explosion in the amount of digital information stored in electronic health records (EHR). While primarily designed for archiving patient clinical information and administrative healthcare tasks, many researchers have found secondary use of these records for various clinical informatics tasks…
We consider the problem of active feature acquisition, where we sequentially select the subset of features in order to achieve the maximum prediction performance in the most cost-effective way. In this work, we formulate this active feature acquisition problem as a reinforcement learning problem, and provide a novel fr…
Model identifies key problems in HIV patients' records.
problem Complex and time-consuming task of identifying patient problems from electronic health records.
method Unsupervised phenotyping approach that jointly learns phenotypes from structured and unstructured data.
result Learned phenotypes and their relatedness are clinically valid and surpass existing methods.
AdaptHetero uses MLI to tailor EHR models for subgroup-specific predictions.
problem Lack of subgroup-specific, operationalizable modeling strategies in EHRs.
method Integrates MLI with unsupervised clustering to identify subgroup-specific characteristics.
result Improves predictive performance by up to 174.39 percent across many subpopulations.
Deep learning predicts opioid use disorder risk in patients.
problem Identifying patients at high risk of opioid use disorder.
method Applied LSTM models to analyze electronic health records of opioid users.
result LSTM model outperformed other methods with F1 score of 0.8023 and AUCROC of 0.9369.
Paper proposes sharing models instead of data for smart health predictions.
problem Sharing sensitive medical data is legally restricted and challenging.
method Train a teacher model on sensitive data, then transfer its knowledge to a student model without accessing original data.
result Student model mimics teacher model performance in making accurate predictions.
MLHO predicts COVID-19 adverse outcomes using past medical records.
problem Predicting adverse outcomes after COVID-19 infection.
method Iterative feature and algorithm selection, sequential representation mining.
result Mean AUC ROC of 0.91 for mortality prediction.
Develops algorithm to find subgroups with different treatment effects in HIV patients.
problem Estimating treatment effects in EHR data with challenges like time-varying confounding.
method SDLD algorithm combining generalized interaction tree and longitudinal targeted maximum likelihood estimation.
result Identifies subgroups of HIV patients at higher risk of weight gain with dolutegravir-containing ARTs.
Neural network predicts cardiovascular events from EHRs with high accuracy.
problem Predicting onset of cardiovascular diseases from electronic health records.
method Multi-task gated recurrent units with attention mechanism.
result Model outperforms clinical risk scores in predicting stroke and myocardial infarction.
CorGAN generates synthetic healthcare records while preserving privacy.
problem Generating realistic synthetic healthcare records while maintaining privacy.
method Combining Convolutional Generative Adversarial Networks and Convolutional Autoencoders to capture correlations between medical features.
result CorGAN generates synthetic data with performance similar to real data in various ML settings.
New method selects recent similar periods for better electricity price forecasting.
problem Improving accuracy in forecasting electricity prices.
method Change-point detection (NOT method) to select calibration periods; estimating autoregressive models only for selected data.
result Significant improvement in forecasting accuracy compared to existing methods.
The wide implementation of electronic health record (EHR) systems facilitates the collection of large-scale health data from real clinical settings. Despite the significant increase in adoption of EHR systems, this data remains largely unexplored, but presents a rich data source for knowledge discovery from patient hea…
New method generates diverse EHR data types while maintaining privacy.
problem Privacy risks in sharing EHRs across large scales.
method Refined GAN model, feature constraints, and utility measures.
result New model preserves EHR statistics, correlations, and constraints.
System identifies power grid location from media recordings.
problem Identifying the origin of power distribution grid from media recordings.
method Cascaded SVM and pole-matching classifiers for grid identification.
result Cascaded system improves accuracy by 15.57%.
New method uses surrogate outcomes and single-record data to improve suicide risk modeling.
problem Lack of historical information in single-record patients hinders modeling rare medical events.
method Hybrid framework combining supervised and unsupervised learning to integrate concurrent and single-record data.
result Single-record data and concurrent diagnoses provide valuable information for improving suicide risk modeling.
A novel memory network improves interpretability and training for EHR analysis.
problem Limited interpretability and training difficulty in traditional memory networks for EHR analysis.
method Proposes a hybrid memory architecture with explicit and blurred memory blocks for improved interpretability and training efficiency.
result The model performs comparably to state-of-the-art methods and enables ready interpretation of results.
ODVICE augments EHR cohorts using ontology to improve analysis robustness.
problem Limited records in cohorts for rare diseases hamper robust analysis.
method Ontology-driven Monte-Carlo graph spanning algorithm for data augmentation.
result ODVICE augmented cohorts show ~30% improvement in AUC over non-augmented datasets.
New method uses probabilistic independence to discover disease signatures from medical records.
problem Insufficiently precise diagnosis of clinical disease leading to treatment failures.
method Unsupervised machine learning using probabilistic independence to disentangle disease patterns.
result Inferred 2000 clinical disease signatures from medical records, improving cancer prediction.
Cardea automates machine learning for EHRs, improving model building efficiency.
problem Lack of a trusted, open-source framework for automated machine learning in EHRs.
method Uses FHIR for data structure, AUTOML frameworks for feature engineering, model selection, and tuning, and an adaptive data assembler.
result Demonstrates framework's effectiveness on 5 prediction tasks, highlighting its flexibility and human competitiveness.
Neural TPPs improve EHR modelling efficiency.
problem Challenges in modelling irregularly timed, noisy EHRs.
method Proposed neural network parameterizations of Temporal Point Processes (TPPs) for EHRs.
result Neural TPPs outperform non-TPP models on EHRs.
Study assesses weakly-supervised methods for rare outcomes in medical records.
problem Identifying patients with specific medical conditions using electronic health records.
method Compared three methods (PheNorm, MAP, and sureLDA) in simulations with varying outcomes and silver labels.
result No single method consistently outperformed others, but sureLDA often did well.
Enhancing spectral embedding for low-dimensional embeddings in rare disease cohorts
problem Representing clinical concepts and patients in electronic health records
method Spectral-based unsupervised learning with flexible knowledge transfer
result Outperforms competing approaches in challenging scenarios
We show how to learn low-dimensional representations (embeddings) of patient visits from the corresponding electronic health record (EHR) where International Classification of Diseases (ICD) diagnosis codes are removed. We expect that these embeddings will be useful for the construction of predictive statistical models…
AI system predicts acute critical illness from EHRs with explainability.
problem Lack of clinical interpretability in AI predictions for acute critical illness.
method Developed an explainable AI early warning score (xAI-EWS) system.
result System provides clinicians with insights into EHR data explaining predictions.