Deep Belief Network predicts lncRNA-disease associations with high accuracy.
problem Accurately identifying lncRNA-disease associations to understand lncRNA functionality and disease mechanism.
method Proposes a DBN-based model using heterogeneous networks and DBN for feature learning.
result Obtained AUC of 0.96 and AUPR of 0.967 on standard dataset.
VGAE learns gene-disease associations from networks, predicting disease-genes.
problem Predicting gene-disease associations from disease-gene networks.
method Introducing VGAE, a variational graph auto-encoder for disease-gene prediction.
result VGAE and C-VGAE outperform baseline methods in disease-gene prediction.
HMRNN combines HMMs and neural networks for Alzheimer's disease forecasting.
problem Improving disease progression modeling with hidden states not fully known.
method Developed HMRNN combining HMMs and recurrent neural networks.
result HMRNN improves disease forecasting and offers novel clinical interpretation.
The paper introduces Precision Disease Networks (PDN) for predicting medical outcomes.
problem Predicting medical outcomes for patients with diseases.
method Building patient-specific disease networks, clustering, and data visualization.
result PDN improves prediction of patient outcomes compared to standard statistical analysis.
Paper uses GANs for efficient rare disease detection.
problem Efficient detection of rare diseases with limited labeled data.
method Semi-supervised learning with GANs.
result Best precision-recall scores compared to baseline techniques.
Deep learning boosts rare disease detection from medical claims.
problem Improving diagnosis and treatment of rare diseases.
method Generative adversarial networks (GANs) and recurrent neural networks for sequence modeling.
result Accurate prediction with 0.56 PR-AUC, outperforming benchmarks.
Model learns disease self-representations for drug repositioning.
problem Drug repositioning for disease treatment.
method Enforces proximity in disease self-representations to preserve human phenome network structure.
result Method outperforms state-of-the-art approaches and produces biologically interpretable disease self-representations.
Graph network predicts circRNA-disease associations using multi-source similarity features.
problem Identifying circRNA-disease associations is challenging and time-consuming.
method Proposes a graph convolution network framework using multi-source similarity information.
result Framework predicts circRNA-disease associations with promising results and outperforms existing methods.
Deep learning model classifies gastrointestinal diseases with high accuracy.
problem Disease detection in the gastrointestinal tract.
method Global features and deep neural networks.
result 95.80% accuracy, 95.87% precision, 95.80% F1-score.
New method predicts Parkinson's using deep neural network latent info.
problem Medical diagnosis of Parkinson's disease.
method Transfer learning, k-means clustering, k-Nearest Neighbour classification of DNN representations.
result Improved prediction of Parkinson's disease based on MRI and DaT Scan data.
ENN method uses expectile regression for genetic data analysis of complex diseases.
problem Discover additional genetic variants contributing to complex diseases.
method Developed an expectile neural network (ENN) method integrating expectile regression and neural networks.
result ENN method outperforms existing expectile regression in discovering genetic variants predisposing to sub-populations.
Deep learning detects Crohn's disease in MRI images.
problem Detecting Crohn's disease in MRI images.
method Residual Networks for feature extraction and soft attention mechanisms for interpretability.
result Deep learning algorithms perform comparably to clinical standards with faster inference.
MOTGNN integrates multi-omics data for disease classification with improved accuracy and interpretability.
problem Challenges in integrating multi-omics data due to high dimensionality, heterogeneity, and lack of reliable interaction networks.
method MOTGNN uses XGBoost for graph construction, modality-specific GNNs for representation learning, and a deep feedforward network for cross-omics integration.
result MOTGNN outperforms state-of-the-art baselines by 5-10% in accuracy, ROC-AUC, and F1-score across three real-world disease datasets.
InceptionGCN improves disease prediction on graph data.
problem Improving disease prediction accuracy on graph data.
method Introduced a new spectral domain architecture with inception modules and varying kernel sizes.
result Significantly improved disease prediction results on two datasets.
DDP models dynamic comorbidity networks from event data.
problem Understanding complex temporal patterns of co-occurring diseases.
method Developed deep diffusion processes (DDP) to model dynamic comorbidity networks.
result DDP enables accurate risk prediction and interpretable disease trajectories.
New network learns image features inductively for disease classification.
problem Pre-processing image features limits network optimization.
method Inductive end-to-end learning with CNN and graph filters trained jointly.
result Significantly improved classification scores and higher stability.
Bayesian approach models neurodegenerative diseases without clinical labels.
problem Personalized, predictive modeling of neurodegenerative diseases.
method Probabilistic programmed deep kernel learning combining Gaussian processes and neural networks.
result Surpasses deep learning in accuracy and timeliness of predicting neurodegeneration.
Novel method identifies proteomic risk markers for Alzheimer disease.
problem Lack of comprehensive proteomic risk markers for Alzheimer disease diagnosis.
method Deep belief network-based feature selection method using proteomic and clinical data.
result Identified an optimal subset of proteins achieving 90% accuracy in Alzheimer disease diagnosis.
Graph Attention Networks predict disease state from single-cell data.
problem Predicting disease state from single-cell data.
method Graph Attention Networks (GAT) for learning from both features and graph structures.
result Achieved 92% accuracy in predicting MS from single-cell data.
We develop three efficient approaches for generating visual explanations from 3D convolutional neural networks (3D-CNNs) for Alzheimer's disease classification. One approach conducts sensitivity analysis on hierarchical 3D image segmentation, and the other two visualize network activations on a spatial map. Visual chec…
Deep neural network classifies DaTscan SPECT images for Parkinson's Disease.
problem Early diagnosis of Parkinson's Disease through objective analysis of SPECT images.
method InceptionV3 architecture with custom binary classifier, 10-fold cross validation.
result Deep neural network achieves high accuracy in classifying DaTscan SPECT images.
Deep learning system tracks stool consistency for GI disease assessment.
problem Lack of objective stool consistency measurements in chronic GI disease.
method Computer vision and deep convolutional neural networks (CNN).
result Developed a stool detection and tracking system.
Generative model designs drug combinations for improved efficacy and reduced side effects.
problem Designing effective drug combinations to overcome resistance and reduce side effects.
method Developed a deep generative model using HVGAE and a novel reward system.
result Network-principled drug combinations show reduced toxicity and potential for new strategies.
VEGN uses graph neural networks to predict disease-causing mutations from genetic variants.
problem Identifying disease-causing mutations from millions of genetic variants.
method VEGN employs a graph neural network on a heterogeneous graph of genes and variants, learning gene-gene interactions.
result VEGN outperforms existing state-of-the-art models in variant effect prediction.
AdaptiveNet tackles disease progression prediction in rheumatoid arthritis using deep neural networks.
problem Predicting disease progression in rheumatoid arthritis using clinical data.
method AdaptiveNet, a novel recurrent neural network architecture, that handles multiple lists of different events and missing data.
result AdaptiveNet outperforms classical baselines in disease progression prediction.
Deep neural networks improve heart disease diagnosis accuracy.
problem Improving accuracy of heart disease diagnosis.
method Design and use of deep neural networks (DNNs) for detecting heart disease based on clinical data.
result HEARO-5 architecture yields 99% accuracy and 0.98 MCC.
Study fairness in vaccine allocation in social networks.
problem Fairness implications of vaccine allocation strategies in social networks.
method Defined precision disease control problem, used ML Fairness Gym to simulate and analyze.
result Different treatment strategies distribute disease burden differently across subgroups.
Paper classifies Parkinson's disease from speech in three languages using CNNs and transfer learning.
problem Classifying Parkinson's disease from speech in multiple languages.
method Convolutional Neural Networks (CNNs) with transfer learning among Spanish, German, and Czech.
result Transfer learning improves model accuracy by up to 8% and balances specificity-sensitivity.
ChronoMID uses neural networks to classify bone disease in mice from micro-CT scans.
problem Classifying bone disease in mice from micro-CT scans.
method ChronoMID applies cross-modal convolutional neural networks to incorporate temporal information from timestamps and difference images.
result The top-performing model achieved 99.54% accuracy, significantly outperforming a baseline CNN.
New method predicts AD progression using MEG brain networks.
problem Early diagnosis and prediction of Alzheimer's disease progression.
method MG2G, a deep learning method that maps brain networks into a latent space.
result MG2G detects subtle brain connectivity patterns and predicts AD progression.
AI-assisted heart disease diagnosis reduces misdiagnosis and saves lives.
problem Misdiagnosis of heart disease leads to unnecessary deaths.
method Developed an AI application using ML and DNN algorithms on a dataset from the Cleveland Clinic Foundation.
result DNN model achieved a 92% accuracy rate, reducing misdiagnosis.
Pattern recognition methods using neuroimaging data for the diagnosis of Alzheimer's disease have been the subject of extensive research in recent years. In this paper, we use deep learning methods, and in particular sparse autoencoders and 3D convolutional neural networks, to build an algorithm that can predict the di…
Wide and deep neural network predicts Alzheimer's progression from shape and clinical data.
problem Predicting Alzheimer's disease progression from shape and clinical data.
method Fused anatomical shape and tabular clinical data in a neural network, employing survival analysis loss.
result The model outperforms shape and clinical models individually.
Integrative analysis of patient health records and neuroimages using MemGCN.
problem Combining EHR and neuroimaging data for disease understanding.
method Memory-Based Graph Convolution Network (MemGCN) framework.
result Superior classification performance in Parkinson's Disease cases versus controls.
Convolutional neural networks improve biopsy image classification for diagnosing Celiac Disease and Environmental Enteropathy.
problem Diagnosing Celiac Disease and Environmental Enteropathy from biopsy images due to histopathologic overlap.
method Proposed a convolutional neural network (CNN) to classify duodenal biopsy images.
result The proposed model achieves high accuracy in classifying biopsy images for CD, EE, and healthy controls.
Bayesian meta-learning predicts Alzheimer's disease progression.
problem Predicting individual Alzheimer's disease progression from limited data.
method Bayesian meta-learning approach that dynamically predicts disease score distributions.
result Bayesian meta-learner outperforms single-task models and deterministic meta-learners, especially for long-term predictions.
Semi-supervised GAN creates synthetic genetic data for disease prediction.
problem Expensive and time-consuming to build large labeled genetic databases.
method Semi-supervised Genetic Generative Adversarial Network (gGAN).
result Model achieved satisfactory results with real genetic data.
Unified framework improves gene prioritization in disease studies.
problem Identifying genes involved in diseases using heterogeneous biological data.
method Network propagation-based gene prioritization with integrated biological information.
result Significant improvements in prioritizing genes not identified by traditional methods.
engGNN combines external and generated graphs to improve disease classification and biomarker discovery.
problem Challenges in integrating omics data due to high dimensionality and small sample sizes.
method Dual-graph framework that integrates external biological networks with data-driven generated graphs.
result engGNN outperforms state-of-the-art methods in disease classification and biomarker discovery.
Framework integrates multi-omic data with network constraints for disease prediction.
problem Challenges in training models from multi-omic data with small sample size.
method Multi-view Factorization AutoEncoder with network constraints.
result Framework predicts disease progression-free interval and patient overall survival.
Proposes Ada-Sit method for mortality prediction of rare diseases.
problem Data insufficiency and clinical diversity of rare diseases make mortality prediction hard.
method Initialization-sharing multi-task learning method (Ada-Sit) for fast adaptation to similar tasks.
result Experimental results show the proposed model is effective for mortality prediction of diverse rare diseases.
Study compares MRI and PET for Alzheimer's classification using deep learning.
problem Balanced comparison of MRI and PET for Alzheimer's disease classification.
method Deep learning with ADNI dataset, fusion of MRI and PET.
result Deep learning shows benefits of using both MRI and PET for Alzheimer's classification.
We investigate the automatic classification of patient discharge notes into standard disease labels. We find that Convolutional Neural Networks with Attention outperform previous algorithms used in this task, and suggest further areas for improvement.
HAMN combines CF models to improve drug repositioning.
problem Efficient drug repositioning with cold start problem.
method Hybrid Attentional Memory Network (HAMN) integrating memory and attention mechanisms.
result HAMN outperforms other models in drug repositioning tasks.
MATCH-Net uses CNNs to predict disease trajectories accurately.
problem Inaccurate prediction of disease trajectories in survival analysis.
method Developed a Missingness-Aware Temporal Convolutional Hitting-time Network (MATCH-Net).
result Demonstrated state-of-the-art performance in real-world Alzheimer's data.
Smartphone app diagnoses pulmonary diseases from chest X-rays.
problem Scarcity of training data and class imbalance issues.
method Data Augmentation Generative Adversarial Network (DAGAN) and Convolutional Siamese Network with attention mechanism.
result Achieved 99.30% and 98.40% testing accuracy on Binary/Multiclass scenarios.
This paper considers the problem of brain disease classification based on connectome data. A connectome is a network representation of a human brain. The typical connectome classification problem is very challenging because of the small sample size and high dimensionality of the data. We propose to use simultaneous app…
Joint models for longitudinal and time-to-event data are commonly used in longitudinal studies to forecast disease trajectories over time. Despite the many advantages of joint modeling, the standard forms suffer from limitations that arise from a fixed model specification and computational difficulties when applied to …