Paper proposes a novel method to estimate differential networks using additional knowledge.
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Neural GDEs improve graph prediction by blending discrete structures and differential equations.
Gradient GA uses gradient information to improve molecular design.
New framework discovers PDEs from sparse, noisy data.
ENN method uses expectile regression for genetic data analysis of complex diseases.
Semi-supervised GAN creates synthetic genetic data for disease prediction.
Discovering causal genetic variants from large genetic association studies poses many difficult challenges. Assessing which genetic markers are involved in determining trait status is a computationally demanding task, especially in the presence of gene-gene interactions. A non-parametric Bayesian approach in the form o…
Optimizing a neural network's performance is a tedious and time taking process, this iterative process does not have any defined solution which can work for all the problems. Optimization can be roughly categorized into - Architecture and Hyperparameter optimization. Many algorithms have been devised to address this pr…
Paper uses AI to predict stock market volatility with neural networks and genetic algorithms.
New method uses DNN for genetic variant identification, controlling randomness and improving interpretability.
EvoNUDGE uses graph neural networks to improve genetic programming performance.
Genetic algorithms optimize neural networks for cosmological data analysis.
There has been significant recent interest towards achieving highly efficient deep neural network architectures. A promising paradigm for achieving this is the concept of evolutionary deep intelligence, which attempts to mimic biological evolution processes to synthesize highly-efficient deep neural networks over succe…
New method designs multilayer nanoparticles using AI.
Deep models improve GWAS by identifying genetic interactions.
We introduce the Genetic-Gated Networks (G2Ns), simple neural networks that combine a gate vector composed of binary genetic genes in the hidden layer(s) of networks. Our method can take both advantages of gradient-free optimization and gradient-based optimization methods, of which the former is effective for problems …
Efficiently infers graph edges from genetic similarity data in landscape genetics.
Genetic algorithms have been widely used in many practical optimization problems. Inspired by natural selection, operators, including mutation, crossover and selection, provide effective heuristics for search and black-box optimization. However, they have not been shown useful for deep reinforcement learning, possibly …
This paper compares Grid Search, Random Search, and Genetic Algorithm for NAS.
In recent years, deep learning methods applying unsupervised learning to train deep layers of neural networks have achieved remarkable results in numerous fields. In the past, many genetic algorithms based methods have been successfully applied to training neural networks. In this paper, we extend previous work and pro…
VEGN uses graph neural networks to predict disease-causing mutations from genetic variants.
A test for neural networks identifies genetic associations.
Deep learning and genetic algorithms speed up cosmological Bayesian inference.
Deep neural network learning can be formulated as a non-convex optimization problem. Existing optimization algorithms, e.g., Adam, can learn the models fast, but may get stuck in local optima easily. In this paper, we introduce a novel optimization algorithm, namely GADAM (Genetic-Evolutionary Adam). GADAM learns deep …
Networks of coupled dynamical systems provide a powerful way to model systems with enormously complex dynamics, such as the human brain. Control of synchronization in such networked systems has far reaching applications in many domains, including engineering and medicine. In this paper, we formulate the synchronization…
Sparse GFA identifies disease factors in FTD subgroups.
As an increasing number of genome-wide association studies reveal the limitations of attempting to explain phenotypic heritability by single genetic loci, there is growing interest for associating complex phenotypes with sets of genetic loci. While several methods for multi-locus mapping have been proposed, it is often…
Study improves chiral photonic metasurface design using neural networks and genetic algorithms.
GEGL uses genetic experts to improve deep learning for molecular design.
New KNN test improves association analysis of high-dimensional sequencing data.
ADNN uses prior knowledge to construct financial features.
We analyze the accuracy of traffic simulations metamodels based on neural networks and gradient boosting models (LightGBM), applied to traffic optimization as fitness functions of genetic algorithms. Our metamodels approximate outcomes of traffic simulations (the total time of waiting on a red signal) taking as an inpu…
We propose a non-parametric regression methodology, Random Forests on Distance Matrices (RFDM), for detecting genetic variants associated to quantitative phenotypes representing the human brain's structure or function, and obtained using neuroimaging techniques. RFDM, which is an extension of decision forests, requires…
Convolutional neural networks (CNNs) are effective at solving difficult problems like visual recognition, speech recognition and natural language processing. However, performance gain comes at the cost of laborious trial-and-error in designing deeper CNN architectures. In this paper, a genetic programming (GP) framewor…
Identifying measurable genetic indicators (or biomarkers) of a specific condition of a biological system is a key element of precision medicine. Indeed it allows to tailor diagnostic, prognostic and treatment choice to individual characteristics of a patient. In machine learning terms, biomarker discovery can be framed…
The widely used genetic pleiotropic analysis of multiple phenotypes are often designed for examining the relationship between common variants and a few phenotypes. They are not suited for both high dimensional phenotypes and high dimensional genotype (next-generation sequencing) data. To overcome these limitations, we …
A promising paradigm for achieving highly efficient deep neural networks is the idea of evolutionary deep intelligence, which mimics biological evolution processes to progressively synthesize more efficient networks. A crucial design factor in evolutionary deep intelligence is the genetic encoding scheme used to simula…
Bayesian symbolic regression uncovers missing physics from data with uncertainty quantification.
Genome-wide association studies (GWAS) have emerged as a rich source of genetic clues into disease biology, and they have revealed strong genetic correlations among many diseases and traits. Some of these genetic correlations may reflect causal relationships. We developed a method to quantify causal relationships betwe…
Novel tests for genetic independence in high-dimensional data.
For precision medicine and personalized treatment, we need to identify predictive markers of disease. We focus on Alzheimer's disease (AD), where magnetic resonance imaging scans provide information about the disease status. By combining imaging with genome sequencing, we aim at identifying rare genetic markers associa…
We present a method of discovering governing differential equations from data without the need to specify a priori the terms to appear in the equation. The input to our method is a dataset (or ensemble of datasets) corresponding to a particular solution (or ensemble of particular solutions) of a differential equation. …
In recent years, deep neural networks have achieved great success in the field of computer vision. However, it is still a big challenge to deploy these deep models on resource-constrained embedded devices such as mobile robots, smart phones and so on. Therefore, network compression for such platforms is a reasonable so…
We introduce GeNet, a method for shotgun metagenomic classification from raw DNA sequences that exploits the known hierarchical structure between labels for training. We provide a comparison with state-of-the-art methods Kraken and Centrifuge on datasets obtained from several sequencing technologies, in which dataset s…
The study develops a machine learning system for credit scoring and default prediction.
Study uses machine learning to predict future health from various health data types.
A new method for joint eQTL mapping and gene network estimation.
Paper addresses class imbalance in disk SMART dataset using GANs and genetic algorithms.