DDP models dynamic comorbidity networks from event data.
problem Understanding complex temporal patterns of co-occurring diseases.
method Developed deep diffusion processes (DDP) to model dynamic comorbidity networks.
result DDP enables accurate risk prediction and interpretable disease trajectories.
Framework identifies comorbidities for frequent ED and inpatient visits.
problem Reducing resource usage and costs in frequent patients.
method Developed MSAR algorithm to identify comorbidities.
result MSAR identifies conditions most associated with reoccurring ED and inpatient visits.
This work proposes a new algorithm for automated and simultaneous phenotyping of multiple co-occurring medical conditions, also referred as comorbidities, using clinical notes from the electronic health records (EHRs). A basic latent factor estimation technique of non-negative matrix factorization (NMF) is augmented wi…
The analysis of comorbidity is an open and complex research field in the branch of psychiatry, where clinical experience and several studies suggest that the relation among the psychiatric disorders may have etiological and treatment implications. In this paper, we are interested in applying latent feature modeling to …
New method enforces encoder sparsity in HPF for more interpretable feature selection.
problem Lack of encoder sparsity in HPF leads to lack of column-clustering property.
method Enforces encoder sparsity using a generalized additive model (GAM).
result Gains ability to perform feature selection and relates each representation to original features.
Interventional cancer clinical trials are generally too restrictive, and some patients are often excluded on the basis of comorbidity, past or concomitant treatments, or the fact that they are over a certain age. The efficacy and safety of new treatments for patients with these characteristics are, therefore, not defin…
Diabetes is a major public health problem in the United States, affecting roughly 30 million people. Diabetes complications, along with the mental health comorbidities that often co-occur with them, are major drivers of high healthcare costs, poor outcomes, and reduced treatment adherence in diabetes. Here, we evaluate…
Synthetic medical data which preserves privacy while maintaining utility can be used as an alternative to real medical data, which has privacy costs and resource constraints associated with it. At present, most models focus on generating cross-sectional health data which is not necessarily representative of real data. …
Deep learning model creates patient representations for scalable EHR-based stratification.
problem Challenges in summarizing and representing patient data from EHRs prevent scalable stratification analysis.
method Unsupervised framework based on deep learning (ConvAE) using word embeddings, CNNs, and autoencoders.
result ConvAE significantly outperformed baselines in clustering diverse patient cohorts, identifying clinically relevant subtypes.
Study uses interviews to automatically detect BD and BPD with good accuracy.
problem Challenges in distinguishing BD and BPD from clinical interviews.
method Developed a multi-modal dataset and used a linear classifier with selected features from interviews.
result Different sets of features characterize BD and BPD, providing insights into their differences.
C-kNN-LSH identifies similar patient histories for causal inference in longitudinal data.
problem Estimating causal effects from longitudinal trajectories with high-dimensional confounding.
method C-kNN-LSH uses locality-sensitive hashing to find clinical twins and estimate treatment effects.
result C-kNN-LSH outperforms existing methods in capturing recovery heterogeneity and estimating policy values.
Deep learning clusters patient time-series data for better prognosis.
problem Clustering time-series data for patient phenotyping and prognosis.
method Deep predictive clustering with novel loss functions for future outcome distribution.
result Model achieves superior clustering performance and identifies meaningful patient subgroups.
Deep Rule Forests identifies drug-drug and drug-disease interactions causing AKI.
problem Identifying drug-drug and drug-disease interactions leading to AKI.
method Deep Rule Forests (DRF) algorithm discovering rules from multilayer tree models.
result DRF model outperforms other algorithms in prediction accuracy and interpretability.
Method for understanding heterogeneous treatment effects in complex causal graphs.
problem Heterogeneity and comorbidity in healthcare problems.
method Developed a new approach to characterize heterogeneous causal effects (HCEs) in graphical contexts, including heterogeneous causal graphs (HCGs) with confounders and mediators.
result Established theoretical forms and properties of HCEs in linear and nonlinear models, and developed interactive structural learning for estimation.
Study develops a dynamic risk model for COVID-19 mortality using UK Biobank data.
problem Developing tools to monitor high-risk patients during the COVID-19 pandemic.
method Data-driven random forest classification model using baseline characteristics and symptoms.
result Model predicts COVID-19 mortality with excellent performance (AUC: 0.91), identifying novel predictors.
The paper estimates personalized treatment effects in medical settings with competing risks.
problem Estimating treatment effectiveness for specific events in the presence of alternative event types.
method Meta-learners combining Cox regression or random survival forests for risk modeling and elastic net regression or random forests for direct CATE modeling.
result Compared meta-learners in multiple simulation settings, providing practical guidance for model selection.
Paper examines global Covid-19 data complexity and finds low intrinsic dimensions.
problem Understanding the complexity of Covid-19 data across countries.
method Used a Bayesian mixture model (Hidalgo) to estimate intrinsic dimensionality.
result Covid-19 data projects onto two low-dimensional manifolds without significant loss of information.
Paper develops machine learning algorithms to learn optimal integer weights for clinical risk scores.
problem Deriving optimal integer weights for clinical risk scores without computational burden.
method Flexible greedy optimization strategy to directly optimize a value function.
result Constructed an integer-weighted comorbidity score for measuring post-discharge mortality risk.
Model identifies key problems in HIV patients' records.
problem Complex and time-consuming task of identifying patient problems from electronic health records.
method Unsupervised phenotyping approach that jointly learns phenotypes from structured and unstructured data.
result Learned phenotypes and their relatedness are clinically valid and surpass existing methods.
Objective: Anemia is a frequent comorbidity in hemodialysis patients that can be successfully treated by administering erythropoiesis-stimulating agents (ESAs). ESAs dosing is currently based on clinical protocols that often do not account for the high inter- and intra-individual variability in the patient's response. …
Analyzes COVID-19 data to predict mortality, forecast spread, and optimize resource allocation.
problem Challenges in patient triage, treatment, and care management during the pandemic.
method Integrated four-step approach combining descriptive, predictive, and prescriptive analytics.
result Optimized resource allocation and informed policy decisions.
Study describes severe dengue ICU patients in Brazil, 2012-2024.
problem Characterize severe dengue ICU patients and identify risk factors.
method Prospective study, descriptive statistics, logistic regression, machine learning.
result Advanced age, comorbidities, leukocytes, and platelets are significant risk factors for complications.
RFN improves GCNs for road networks, outperforming state-of-the-art by 21%-40%.
problem Leveraging the structure of road networks effectively in machine learning tasks.
method Introducing RFN, a novel GCN specifically designed for road networks.
result RFN outperforms state-of-the-art GCNs by 21%-40% on road network tasks.
This survey clarifies dynamic network terminology and reviews GNN models for dynamic networks.
problem Ambiguity in dynamic network terminology and lack of GNN models for dynamic networks.
method Established consistent terminology and notation for dynamic networks, reviewed GNN models.
result Comprehensive survey of dynamic graph neural network models.
From the perspective of network analysis, the ubiquitous networks are comprised of regular and irregular components, which makes uncovering the complexity of network structures to be a fundamental challenge. Exploring the regular information and identifying the roles of microscopic elements in network data can help us …
DCNs mimic neuronal networks for improved neural classification.
problem Lack of topological similarity between DNNs and biological neural networks.
method Developed DCNs with topologies inspired by real-world neuronal networks.
result High classification accuracy achieved by DCNs.
Chemical networks outperform spiking neural networks in classification tasks.
problem Learning tasks with spiking neural networks require hidden layers, which are computationally expensive.
method Used deterministic mass-action kinetics to prove chemical reaction networks without hidden layers can solve tasks previously solved by spiking neural networks.
result A chemical reaction network without hidden layers outperforms a spiking neural network with hidden layers in a handwritten digit classification task.
Deep ReLU networks can be simplified to a three-layer model.
problem Understanding the behavior of deep neural networks.
method Constructive proof and algorithm to transform deep networks into shallow ones.
result Deep ReLU networks can be represented by a simpler three-layer structure.
Tackles network structure inference from time series data using GNN.
problem Inferring network structure from incomplete or no information.
method Gumbel Graph Network (GGN) model for network reconstruction and completion.
result GGN can reconstruct up to 100% network structure and infer missing parts with up to 90% accuracy.
This paper explores loss landscapes of sparse neural networks, finding unique characteristics compared to dense networks.
problem Understanding the loss landscape of sparse neural networks, especially one-hidden-layer networks.
method Analyzes sparse networks with dense and sparse final layers, focusing on linear and non-linear models.
result Sparse networks can have no spurious valleys under certain conditions, but spurious valleys and minima can exist for wide sparse networks.
New approach learns latent motifs in networks for mesoscale structure analysis.
problem Understanding large-scale behavior in complex systems through mesoscale structures.
method Network dictionary learning (NDL) combining network sampling and nonnegative matrix factorization.
result Networks can be approximated using a small set of latent motifs.
A challenging problem in complex networks is the network reconstruction problem from data. This work deals with a class of networks denoted as conserved networks, in which a flow associated with every edge and the flows are conserved at all non-source and non-sink nodes. We propose a novel polynomial time algorithm to …
Social network analysis is an important problem in data mining. A fundamental step for analyzing social networks is to encode network data into low-dimensional representations, i.e., network embeddings, so that the network topology structure and other attribute information can be effectively preserved. Network represen…
Taking inspiration from biological evolution, we explore the idea of "Can deep neural networks evolve naturally over successive generations into highly efficient deep neural networks?" by introducing the notion of synthesizing new highly efficient, yet powerful deep neural networks over successive generations via an ev…
SyNGLER generates synthetic networks efficiently while preserving key structural properties.
problem Efficiently generating realistic synthetic networks with preserved structural properties.
method SyNGLER uses latent space network models to learn and reconstruct node embeddings, then generates synthetic networks.
result SyNGLER produces synthetic networks that better preserve key network characteristics than existing approaches.
Secret neural networks hidden within trained models.
problem Excess capacity in neural networks allows embedding secret models.
method Novel framework for hiding secret neural networks within carrier networks.
result Detection of hidden networks is computationally infeasible.
Natural graph networks are a new class of graph neural networks that are more flexible and scalable.
problem Traditional graph neural networks are limited by equivariance to node permutations.
method Introduced natural graph networks, which are more flexible and scalable than conventional graph neural networks.
result Natural graph networks are as scalable as conventional message passing graph neural networks but more flexible.
The structure of complex networks has been of interest in many scientific and engineering disciplines over the decades. A number of studies in the field have been focused on finding the common properties among different kinds of networks such as heavy-tail degree distribution, small-worldness and modular structure and …
Convolutional networks outperform fully-connected ones in certain tasks.
problem Understanding the computational advantage of convolutional networks over fully-connected networks.
method Demonstrated a computational advantage through a specific problem class.
result Convolutional networks can solve certain problems that fully-connected networks cannot, even with gradient descent.
Proposes a graph neural network for traffic forecasting in WANs.
problem Traffic forecasting challenges in WANs due to dynamic and large data volumes.
method Dynamic diffusion convolutional recurrent neural networks for multistep traffic forecasting.
result Significant improvements in forecasting accuracy compared to classical methods.
Researchers derive exact priors for finite Bayesian neural networks.
problem Understanding non-Gaussian priors in finite Bayesian neural networks.
method Analytical derivation of function space priors for finite fully-connected feedforward networks.
result Exact solutions for priors of finite networks, including Meijer G-function for linear networks and mixtures for ReLU networks.
i-cNRL learns network differences with interpretability.
problem Comparing unique network characteristics.
method Contrastive network representation learning (cNRL) integrating machine learning schemes.
result i-cNRL reveals unique network patterns with interpretability.
Deep and wide networks are shown to be equivalent in terms of their capability.
problem The relationship between the width and depth of neural networks.
method Formulated transforms to map networks, used polynomial representations.
result Deep and wide networks are quasi-equivalent with an arbitrarily small error.
We show that deep networks are better than shallow networks at approximating functions that can be expressed as a composition of functions described by a directed acyclic graph, because the deep networks can be designed to have the same compositional structure, while a shallow network cannot exploit this knowledge. Thu…
DCGANs generate drainage networks quickly from samples.
problem High computational costs in generating large numbers of drainage networks.
method DCGANs trained with connectivity-informed directional information.
result Connectivity-informed DCGANs outperform other methods in reproducing accurate drainage networks.
A network embedding consists of a vector representation for each node in the network. Its usefulness has been shown in many real-world application domains, such as social networks and web networks. Directed networks with text associated with each node, such as software package dependency networks, are commonplace. Howe…
Quantum neural network and tensor network models outperform classical models in Japanese stock market predictions.
problem Improving stock return predictions using quantum and quantum-inspired machine learning.
method Evaluation of quantum neural network and tensor network models against classical models like linear and neural networks.
result Tensor network model outperforms classical models in Japanese stock market, including linear and neural network models.
Study deep maxout networks and their equivalence to Gaussian processes.
problem Understanding neural networks with infinite width.
method Derive equivalence between deep maxout networks and Gaussian processes, characterize maxout kernel, and provide efficient numerical implementation.
result Bayesian inference based on deep maxout network kernel leads to competitive results compared to finite-width counterparts and deep neural network kernels.