Random shuffle method boosts HF dataset size 10-21 times.
problem Narrow dataset cardinality in HF clinical studies.
method Random shuffle method to enhance dataset size.
result Enhanced HF dataset size 10-21 times.
On-device research index
arXiv research
A locally-built, LLM-digested index of recent arXiv papers in quant finance, geometry/topology, and statistical ML — keyword search served straight from SQLite on this machine.
168,694 papers · 148 categories
Trend · papers per month
48 results for “clinical data science”
Foundation models alter medical data science workflow, challenging veridical data science principles.
problem Foundation models disrupt traditional data science practices in medicine.
method Critically examined the medical foundation model lifecycle and its deviation from veridical data science principles.
result Foundation models challenge veridical data science principles of predictability, computability, and stability.
With the maturation of metabolomics science and proliferation of biobanks, clinical metabolic profiling is an increasingly opportunistic frontier for advancing translational clinical research. Automated Machine Learning (AutoML) approaches provide exciting opportunity to guide feature selection in agnostic metabolic pr…
MIM adds indicator variables to improve model performance on incomplete data.
problem Missing data in incomplete data sets.
method Missing Indicator Method (MIM) and Selective MIM (SMIM).
result MIM improves model performance for informative missing values and high-dimensional data.
Proposes isotonic regression for calibrating Deep Cox models' survival probabilities.
problem Poor calibration of Deep Cox models' survival probabilities.
method Isotonic regression for post hoc calibration of Deep Cox models.
result Establishes favorable theoretical guarantees and demonstrates empirical effectiveness.
Dynamic treatment regimes are of growing interest across the clinical sciences as these regimes provide one way to operationalize and thus inform sequential personalized clinical decision making. A dynamic treatment regime is a sequence of decision rules, with a decision rule per stage of clinical intervention; each de…
Deep transfer learning boosts single-EEG arousal detection accuracy.
problem Challenges in machine learning due to channel mismatch across different EEG datasets.
method Transfer learning strategy to adapt a multivariate model to single-channel EEG data.
result Fine-tuned model achieves similar performance to baseline model and significantly outperforms a single-channel model.
Increasing volume of Electronic Health Records (EHR) in recent years provides great opportunities for data scientists to collaborate on different aspects of healthcare research by applying advanced analytics to these EHR clinical data. A key requirement however is obtaining meaningful insights from high dimensional, sp…
Increasing volume of Electronic Health Records (EHR) in recent years provides great opportunities for data scientists to collaborate on different aspects of healthcare research by applying advanced analytics to these EHR clinical data. A key requirement however is obtaining meaningful insights from high dimensional, sp…
Deep learning for integrating diverse clinical measurements.
problem Combining data from different measurement instruments in longitudinal clinical registries.
method Domain adaptation using deep learning for mapping items from different instruments.
result Domain adaptation can recover latent trajectories even with limited data and misalignment.
In both the fields of computer science and medicine there is very strong interest in developing personalized treatment policies for patients who have variable responses to treatments. In particular, I aim to find an optimal personalized treatment policy which is a non-deterministic function of the patient specific cova…
New MMD estimators detect differences in missing paired data.
problem Handling missing data in matched pairs with complex distributions.
method Maximum mean discrepancy (MMD) estimators for complex data with missing values.
result Valid and consistent estimators detect differences in data distributions.
MetaPred: Meta-Learning for Clinical Risk Prediction with Limited Patient Electronic Health Recordscs.LG
In recent years, increasingly augmentation of health data, such as patient Electronic Health Records (EHR), are becoming readily available. This provides an unprecedented opportunity for knowledge discovery and data mining algorithms to dig insights from them, which can, later on, be helpful to the improvement of the q…
Study designs statistical inference for collaborative science teams.
problem Maintaining scientific rigor in distributed, collaborative research.
method Analyzes hypothesis testing with strategic agents and principals.
result Principal can design policies to control posterior probability of null.
Teaching reproducible research for medical students and postgraduate pharmaceutical scientistsstat.ML
Teaches reproducible research to medical students and postgrads.
problem Lack of reproducibility in medical research practices.
method Designed and delivered a lecture series on reproducible research.
result Encountered practical obstacles in reproducing a published analysis.
In a context where most published articles are devoted to the development of "new methods", comparison studies are generally appreciated by readers but surprisingly given poor consideration by many scientific journals. In connection with recent articles on over-optimism and epistemology published in Bioinformatics, thi…
At this moment, databanks worldwide contain brain images of previously unimaginable numbers. Combined with developments in data science, these massive data provide the potential to better understand the genetic underpinnings of brain diseases. However, different datasets, which are stored at different institutions, can…
Advances in computational science offer a principled pipeline for predictive modeling of cardiovascular flows and aspire to provide a valuable tool for monitoring, diagnostics and surgical planning. Such models can be nowadays deployed on large patient-specific topologies of systemic arterial networks and return detail…
AI improves precision health through adaptive interventions.
problem Improving healthcare through personalized and dynamic treatments.
method Reinforcement learning (RL) for adaptive interventions in digital health.
result RL shows promise in dynamic healthcare problems.
Clinical AI models fail to transfer between sites due to site-specific practices.
problem Clinical AI models perform poorly at new sites.
method Identify and isolate site-specific clinical practices affecting data distribution.
result A potential solution to improve model transferability.
Modern health data science applications leverage abundant molecular and electronic health data, providing opportunities for machine learning to build statistical models to support clinical practice. Time-to-event analysis, also called survival analysis, stands as one of the most representative examples of such statisti…
Aims to integrate AI and modelling for patient health forecasting.
problem Personalized, precise treatment plans for patients.
method Graph neural network (GNNs) and generative adversarial network (GANs) for probabilistic simulations.
result Demonstrated integration of molecular data for predicting physiological state evolution.
BioFinBERT analyzes sentiment of biotech press releases and financial text around inflection points.
problem Analyzing sentiment of biotech press releases and financial text around inflection points.
method Finetuning BioBERT on financial datasets to create BioFinBERT for sentiment analysis.
result BioFinBERT accurately analyzes sentiment of biotech press releases and financial text around inflection points.
The paper predicts diseases using both clinical and genomics data.
problem Clinical predictions using genomics data are not common.
method Integrated clinical and genomics datasets, machine learning, Principal Component Analysis for feature selection.
result 73% accuracy in predicting 75 disease classes.
Late fusion of clinical notes and physiological data improves ICU mortality prediction.
problem Improving ICU mortality prediction using multimodal data.
method Late fusion of clinical notes and physiological time series data with a deep learning architecture.
result Late fusion approach provides statistically significant improvement in mortality prediction performance.
The paper explores using historical data to improve clinical trial analysis by optimizing covariate weights.
problem Limited covariates in small clinical trials reduce the effectiveness of analysis.
method Leverage historical data to pre-specify covariate weights as a composite covariate.
result A composite covariate improves the cost/benefit ratio and reduces overfitting in small clinical trials.
Skin cancer is one of the most common types of cancer around the world. For this reason, over the past years, different approaches have been proposed to assist detect it. Nonetheless, most of them are based only on dermoscopy images and do not take into account the patient clinical information. In this work, first, we …
Causal inference from observational data is the goal of many data analyses in the health and social sciences. However, academic statistics has often frowned upon data analyses with a causal objective. The introduction of the term "data science" provides a historic opportunity to redefine data analysis in such a way tha…
The reliability of a deep learning model in clinical out-of-distribution MRI data: a multicohort studyphysics.med-ph
Deep learning (DL) methods have in recent years yielded impressive results in medical imaging, with the potential to function as clinical aid to radiologists. However, DL models in medical imaging are often trained on public research cohorts with images acquired with a single scanner or with strict protocol harmonizati…
Data Science is currently a popular field of science attracting expertise from very diverse backgrounds. Current learning practices need to acknowledge this and adapt to it. This paper summarises some experiences relating to such learning approaches from teaching a postgraduate Data Science module, and draws some learn…
This study improves lung tumor segmentation in mice MRI scans with nnU-Net, reducing annotation needs.
problem Accurate lung tumor segmentation in mice MRI scans for drug discovery.
method Optimized nnU-Net 3D model for lung tumor segmentation with minimal annotations.
result nnU-Net 3D models outperform 2D models in MRI mice scans, requiring fewer annotations.
Convolutional neural networks (ConvNets) have demonstrated an exceptional capacity to discern visual patterns from digital images and signals. Unfortunately, such powerful ConvNets do not generalize well to arbitrary-shaped manifolds, where data representation does not fit into a tensor-like grid. Hence, many fields of…
Interpretable Generative and Discriminative Learning for Multimodal and Incomplete Clinical Datastat.ML
Bayesian approach for handling incomplete clinical data.
problem Challenges in machine learning with multimodal, incomplete clinical data.
method Generative and discriminative learning, semi-supervised strategy, imputation of missing views.
result Automatic imputation of missing views and robust inference across different data sources.
Enhances generative model for clinical data privacy and accuracy.
problem Data privacy in electronic patient records.
method Improves a time-series generative model with privacy safeguards.
result DP-TimeGAN achieves a mean authenticity of 0.778 on the CKD dataset.
Today, the prominence of data science within organizations has given rise to teams of data science workers collaborating on extracting insights from data, as opposed to individual data scientists working alone. However, we still lack a deep understanding of how data science workers collaborate in practice. In this work…
System suggests clinical concepts in real-time for faster note creation.
problem Efficiently creating structured clinical notes with minimal keystrokes.
method Contextual autocompletion using shallow neural networks.
result Reduces keystrokes by 67% in real hospital environments.
Defines data science as a natural ecosystem with challenges and missions.
problem Challenges and missions in data science due to 5D complexities and data life cycle phases.
method Systemic and data-centric view of data science as a fusion of data universe and its challenges, formalizing a general-purpose architecture.
result Essential data science as a natural ecosystem integrating specific disciplines and high-impact applications.
Causal ML predicts treatment outcomes, aiding personalized medicine.
problem Predicting individualized treatment effects for personalized medicine.
method Flexible, data-driven methods using causal inference with clinical trial and real-world data.
result Causal ML allows for estimating individualized treatment effects.
Unified model combines neural networks and dictionary learning for clinical predictions from brain data.
problem Predicting clinical severity from brain imaging data.
method Combines neural networks with dictionary learning to model patient-specific and shared features.
result Unified model outperforms state-of-the-art methods in predicting clinical severity.
Machine learning predicts patient recruitment for clinical trials.
problem Improving patient recruitment prediction for clinical trials.
method Machine learning methods applied to historical clinical trial data.
result Reduced prediction error compared to current industry standards.
Study improves healthcare time series imputation by considering structured missingness.
problem Structured missingness in clinical data impacts time series imputation models.
method Analysis of different masking strategies on imputation methods using PhysioNet Challenge 2012 dataset.
result Masking choices significantly affect imputation accuracy and clinical prediction.
New method detects biomarker-treatment interactions in clinical trials.
problem Detecting interactions between high-dimensional biomarkers and treatments in randomized trials.
method Two-stage penalized regression screening using ridge regression for multivariate screening.
result Ridge regression screening provides greater power than traditional methods in correlated data.
AI predicts medical specialty diagnostic choices from EHR records.
problem Predicting timely medical specialty diagnostic workups for patients.
method Ensemble of feed-forward neural networks trained on EHR data.
result Significantly higher accuracy compared to traditional checklists.
The medical research facilitates to acquire a diverse type of data from the same individual for particular cancer. Recent studies show that utilizing such diverse data results in more accurate predictions. The major challenge faced is how to utilize such diverse data sets in an effective way. In this paper, we introduc…
TrialGraph uses graph machine learning to improve clinical trial design and predict side effects.
problem Complexity and cost in clinical trials hinder drug development.
method Curated clinical trial data set converted to graph-structured formats, applied graph machine learning algorithms.
result MetaPath2Vec algorithm performed exceptionally well, improving prediction accuracy.
Health care is one of the most exciting frontiers in data mining and machine learning. Successful adoption of electronic health records (EHRs) created an explosion in digital clinical data available for analysis, but progress in machine learning for healthcare research has been difficult to measure because of the absen…
ML methods improve planetary science data analysis.
problem Insufficient use of ML in planetary science.
method Ten recommendations for integrating ML in planetary science.
result Expanding planetary science insights from large datasets.
Alzheimer's disease (AD) is a degenerative brain disease impairing a person's ability to perform day to day activities. The clinical manifestations of Alzheimer's disease are characterized by heterogeneity in age, disease span, progression rate, impairment of memory and cognitive abilities. Due to these variabilities, …