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48 results for clinical coding

Clinical notes are text documents that are created by clinicians for each patient encounter. They are typically accompanied by medical codes, which describe the diagnosis and treatment. Annotating these codes is labor intensive and error prone; furthermore, the connection between the codes and the text is not annotated…

2018-02-15abs ↗pdf ↗

Characterization of a patient clinical phenotype is central to biomedical informatics. ICD codes, assigned to inpatient encounters by coders, is important for population health and cohort discovery when clinical information is limited. While ICD codes are assigned to patients by professionals trained and certified in c…

2018-11-28abs ↗pdf ↗

AI generates a sequence of death causes from hospital records.

problem Accurate death reporting for vital statistics and policy formulation.
method Neural machine translation models to generate causal chains, incorporating medical domain knowledge.
result Achieved 16.04 BLEU score for generating accurate causal chains.

Framework harmonizes EHR data across institutions for better analysis.

problem Heterogeneity of medical codes and terminologies hinder EHR data analysis.
method MASH (Multi-source Automated Structured Hierarchy) uses neural optimal transport and learned hyperbolic embeddings to align and structure EHR data.
result MASH generates interpretable hierarchical graphs for unstructured local laboratory codes.

We introduce SparseVM, a method that registers clinical-quality 3D MR scans both faster and more accurately than previously possible. Deformable alignment, or registration, of clinical scans is a fundamental task for many clinical neuroscience studies. However, most registration algorithms are designed for high-resolut…

2018-12-17abs ↗pdf ↗

Graph-based framework predicts ADR signals from clinical data.

problem Detecting ADRs in post-market surveillance using clinical data.
method Developed a Drug-disease graph with Graph Neural Network for ADR signal prediction.
result Improved AUROC and AUPRC performance (0.795 and 0.775) compared to other algorithms.

Machine learning guides clinicians in predictive modeling using big data.

problem Insufficient understanding of machine learning among clinicians hinders its adoption.
method Provides a series of guides on machine learning principles, resampling, model evaluation, and coding.
result Clinicians need methodological rigor and clarity to use machine learning effectively.

SARD improves deep learning clinical prediction performance.

problem Deep learning models struggle to match linear models in healthcare predictions.
method Reverse Distillation to initialize deep models, combined with contextual and temporal embeddings.
result SARD outperforms state-of-the-art methods on clinical prediction outcomes.

The role of automatic electrocardiogram (ECG) analysis in clinical practice is limited by the accuracy of existing models. Deep Neural Networks (DNNs) are models composed of stacked transformations that learn tasks by examples. This technology has recently achieved striking success in a variety of task and there are gr…

2019-04-02abs ↗pdf ↗

Method predicts biomarker trajectories with uncertainty bands for Alzheimer's disease.

problem Uncertainty in biomarker predictions poses risks in clinical deployment.
method Conformal prediction for randomly-timed biomarker trajectories.
result Conformal bands achieve desired coverage and are tighter than baseline.

Feature engineering remains a major bottleneck when creating predictive systems from electronic medical records. At present, an important missing element is detecting predictive regular clinical motifs from irregular episodic records. We present Deepr (short for Deep record), a new end-to-end deep learning system that …

2016-07-26abs ↗pdf ↗

Facial pain expression is an important modality for assessing pain, especially when the patient's verbal ability to communicate is impaired. The facial muscle-based action units (AUs), which are defined by the Facial Action Coding System (FACS), have been widely studied and are highly reliable as a method for detecting…

2018-11-13abs ↗pdf ↗

Neural model predicts survival outcomes and reveals feature relationships.

problem Predicting time-to-event outcomes and understanding feature relationships in clinical data.
method Survival and topic modeling combined in a neural network framework.
result Neural survival-supervised topic models achieve competitive accuracy with interpretability.

Machine learning systems have received much attention recently for their ability to achieve expert-level performance on clinical tasks, particularly in medical imaging. Here, we examine the extent to which state-of-the-art deep learning classifiers trained to yield diagnostic labels from X-ray images are biased with re…

2020-02-14abs ↗pdf ↗

Deep learning models (aka Deep Neural Networks) have revolutionized many fields including computer vision, natural language processing, speech recognition, and is being increasingly used in clinical healthcare applications. However, few works exist which have benchmarked the performance of the deep learning models with…

2017-10-23abs ↗pdf ↗

We show how to learn low-dimensional representations (embeddings) of patient visits from the corresponding electronic health record (EHR) where International Classification of Diseases (ICD) diagnosis codes are removed. We expect that these embeddings will be useful for the construction of predictive statistical models…

2018-03-26abs ↗pdf ↗

This work combines deep learning and sparse coding for CT image reconstruction.

problem Improving image quality in low-dose CT scans.
method Sparse signal representation using learned dictionaries, inspired by variational autoencoders and deep learning techniques.
result Regularization with learned dictionaries achieves competitive performance in CT reconstruction.

Enhances medical code predictions for multi-morbidity patients using text classification.

problem Improving accuracy in predicting medical codes for patients with multiple illnesses.
method Used machine learning techniques, including multi-label medical text classification, to enhance predictions.
result High dimensional embeddings pre-trained on health data significantly improve multi-label classification performance.

Paper proposes multimodal contrastive learning for EHR data.

problem Separate treatment of structured and unstructured EHR data.
method Proposes a multimodal feature embedding generative model and a multimodal contrastive loss.
result Multimodal learning yields better feature representation than single-modality learning.

Bayesian model enhances phenotype discovery in asthma EHRs.

problem Lack of interpretability in unsupervised learning phenotyping of EHR data.
method Operationalized a Bayesian latent class framework with clinical knowledge priors.
result Identified an asthma sub-phenotype with elevated eosinophil levels and allergy markers.

CSGM framework applied to clinical MRI data for robust reconstructions.

problem Applying deep generative priors to clinical MRI data for high-quality reconstructions.
method Training a generative prior on brain scans from the fastMRI dataset and using Langevin dynamics for posterior sampling.
result Posterior sampling via Langevin dynamics achieves high quality reconstructions in clinical MRI data.

Novel model improves clinical risk prediction by transferring knowledge between tasks over time.

problem Negative transfer in multi-task learning for clinical risk prediction.
method Temporal Probabilistic Asymmetric Multi-Task Learning (TPAMTL).
result Significantly outperforms various deep learning models for time-series prediction.

Non-synonymous single nucleotide polymorphisms (nsSNPs) are single nucleotide substitution occurring in the coding region of a gene and leads to a change in amino-acid sequence of protein. The studies have shown these variations may be associated with disease. Thus, investigating the effects of nsSNPs on protein functi…

2018-05-06abs ↗pdf ↗

Self-supervised learning improves ECG classification performance.

problem Label scarcity in clinical 12-lead ECG data.
method Adapted self-supervised methods to ECG domain, focusing on contrastive representations and latent forecasting.
result Contrastive predictive coding adaptation yields linear evaluation performance only 0.5% below supervised performance.

We propose a novel Wasserstein method with a distillation mechanism, yielding joint learning of word embeddings and topics. The proposed method is based on the fact that the Euclidean distance between word embeddings may be employed as the underlying distance in the Wasserstein topic model. The word distributions of to…

2018-09-12abs ↗pdf ↗

Clinical notes contain a large amount of clinically valuable information that is ignored in many clinical decision support systems due to the difficulty that comes with mining that information. Recent work has found success leveraging deep learning models for the prediction of clinical outcomes using clinical notes. Ho…

2019-10-30abs ↗pdf ↗