MRI identifies chronic symptoms in mTBI patients.
problem Chronic symptoms in mTBI patients are hard to characterize.
method Multi-parametric MRI and low-dimensional projection.
result MRI metrics correlate with patient symptoms.
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48 results for “chronic symptoms”
Purpose - Functional bowel diseases, including irritable bowel syndrome, chronic constipation, and chronic diarrhea, are some of the most common diseases seen in clinical practice. Many patients describe a range of triggers for altered bowel consistency and symptoms. However, characterization of the relationship betwee…
Respiratory infections and chronic respiratory diseases impose a heavy health burden worldwide. Coughing is one of the most common symptoms of many such infections, and can be indicative of flare-ups of chronic respiratory diseases. Whether at a clinical or public health level, the capacity to identify bouts of coughin…
Bipolar disorder (BPD) is a chronic mental illness characterized by extreme mood and energy changes from mania to depression. These changes drive behaviors that often lead to devastating personal or social consequences. BPD is managed clinically with regular interactions with care providers, who assess mood, energy lev…
Paper characterizes early-stage dementia signatures from sensor data.
problem Detecting early-stage dementia from sensor data.
method Developed bespoke behavioural models from longitudinal sensor data.
result Found subtle differences in sleep quality and wandering between dementia patients and controls.
Study uses interviews to automatically detect BD and BPD with good accuracy.
problem Challenges in distinguishing BD and BPD from clinical interviews.
method Developed a multi-modal dataset and used a linear classifier with selected features from interviews.
result Different sets of features characterize BD and BPD, providing insights into their differences.
Celiac Disease (CD) is a chronic autoimmune disease that affects the small intestine in genetically predisposed children and adults. Gluten exposure triggers an inflammatory cascade which leads to compromised intestinal barrier function. If this enteropathy is unrecognized, this can lead to anemia, decreased bone densi…
We investigate the use of self-tracking data and unsupervised mixed-membership models to phenotype endometriosis. Endometriosis is a systemic, chronic condition of women in reproductive age and, at the same time, a highly enigmatic condition with no known biomarkers to monitor its progression and no established staging…
Learning-based Computer-aided Prescription Model for Parkinson's Disease: A Data-driven Perspectivecs.LG
A model learns symptom-drug relations for PD patients.
problem Automatic prescription recommendation for Parkinson's Disease patients.
method Builds a dataset of PD symptoms and prescriptions, learns latent symptom space, uses alternating optimization.
result Effective in recommending suitable prescription drugs for new PD patients.
Cervical spondylosis (CS) is a common chronic disease that affects up to two-thirds of the population and poses a serious burden on individuals and society. The early identification has significant value in improving cure rate and reducing costs. However, the pathology is complex, and the mild symptoms increase the dif…
Bayesian networks and ML improve COVID-19 symptom classification and severity analysis.
problem Understanding the relationship between COVID-19 symptoms and demographic variables.
method Bayesian network structure learning followed by unsupervised clustering and demographic symptom identification.
result 99.99% testing accuracy compared to 41.15% for a heuristic method.
Study integrates causal inference and temporal complexity measures to analyze mental health symptoms.
problem Examining how individual symptom trajectories reveal diagnostic patterns in mental disorders.
method Causal inference, graph analysis, temporal complexity measures, machine learning.
result 91% accuracy in diagnosing symptom dynamics, highlighting disorder-specific causal mechanisms.
Acute respiratory infections have epidemic and pandemic potential and thus are being studied worldwide, albeit in many different contexts and study formats. Predicting infection from symptom data is critical, though using symptom data from varied studies in aggregate is challenging because the data is collected in diff…
A Disease Diagnosis and Treatment Recommendation System Based on Big Data Mining and Cloud Computingcs.LG
It is crucial to provide compatible treatment schemes for a disease according to various symptoms at different stages. However, most classification methods might be ineffective in accurately classifying a disease that holds the characteristics of multiple treatment stages, various symptoms, and multi-pathogenesis. More…
Proposes a new model for predicting chronic conditions over time.
problem Predicting complex relationships between multiple chronic conditions.
method Continuous time Bayesian network with adaptive regularization for structure and parameter learning.
result Proposed model provides sparse, intuitive representation of chronic condition relationships.
Chronicals boosts LLM fine-tuning speed by 3.51x over Unsloth.
problem Memory bottleneck in fine-tuning large language models.
method Four optimizations: fused kernels, cross-entropy reduction, LoRA+, and sequence packing.
result 3.51x speedup on A100-40GB with Qwen2.5-0.5B.
Simulation framework assesses ROI of chronic disease adherence and policy timing.
problem Uncertainty in ROI of adherence-enhancing interventions under heterogeneous patient behavior and socioeconomic variation.
method Simulation-based framework integrating disease progression, time-varying adherence, and policy timing.
result Early and adaptive interventions yield highest ROI, exceeding 20% under certain conditions.
New fair regression method improves fairness in chronic kidney disease classification.
problem Mitigating societal bias in health care for multiple groups.
method Penalized fair regression framework for multiple groups, with penalties for true positive rate disparity.
result Achieves fairness-accuracy frontier beyond existing methods in simulations and real-world data.
This paper studies the trade-off between model accuracy and coverage for diagnosis models used by patients.
problem Balancing accuracy and coverage in diagnosis models for patient use.
method Learned diagnosis models with varying coverage from EHR data.
result A 1% drop in top-3 accuracy for every 10 diseases added to the coverage.
This paper introduces a novel low-cost device prototype for the automatic diagnosis of diseases, utilizing inputted symptoms and personal background. The engineering goal is to solve the problem of limited healthcare access with a single device. Diagnosing diseases automatically is an immense challenge, owing to their …
Towards automated symptoms assessment in mental healthphysics.med-ph
Activity and motion analysis has the potential to be used as a diagnostic tool for mental disorders. However, to-date, little work has been performed in turning stratification measures of activity into useful symptom markers. The research presented in this thesis has focused on the identification of objective activity …
Enhances generative model for clinical data privacy and accuracy.
problem Data privacy in electronic patient records.
method Improves a time-series generative model with privacy safeguards.
result DP-TimeGAN achieves a mean authenticity of 0.778 on the CKD dataset.
Deep learning diagnoses MS from smartphone data.
problem Diagnosing MS with complex clinical assessments and tests.
method Deep-learning approach using smartphone-derived digital biomarkers.
result Deep-learning models distinguish MS with 88% accuracy.
mcanalysis quantifies menstrual cycle effects in health data.
problem Lack of standardised statistical methods for menstrual cycle research.
method Fourier-basis generalised additive model (GAM) pipeline.
result Nine out of 15 health outcomes showed significant association with menstrual cycle.
Crashes : symptoms, diagnoses and remediescond-mat.stat-mech
A brief historical perspective is first given concerning financial crashes, - from the 17th till the 20th century. In modern times, it seems that log periodic oscillations are found before crashes in several financial indices. The same is found in sand pile avalanches on Sierpinski gaskets. A discussion pertains to the…
Study uses machine learning and survival analysis to predict CKD progression.
problem Early detection and management of CKD to reduce ESRD risk.
method Combines machine learning and classical statistical models to identify novel CKD progression predictors.
result Deep learning models outperform other methods in predicting CKD progression.
Novel framework detects CKD in diabetic patients using sparse EHR representations.
problem Early detection of CKD in diabetic patients.
method Sparse longitudinal representations of EHR data.
result Proposed model achieves higher predictive performance than baselines.
GWN improves multimodal data fusion accuracy for chronic pain patients.
problem Dynamic and unspecified uncertainties in multimodal data fusion.
method Inspired by Global Workspace Theory, GWN is a neural network architecture that dynamically attends to multiple modalities.
result GWN achieved higher F1 scores (0.92 and 0.75) for multimodal discrimination and classification tasks.
Machine learning predicts obesity causes using genetic and imaging data.
problem Predicting causes of obesity in children and adults.
method Use ML techniques like decision trees, SVM, RF, GBM, LASSO, BN, and ANN on genetic and imaging data.
result ML models accurately predict obesity causes and chronic diseases.
Prediction of the future trajectory of a disease is an important challenge for personalized medicine and population health management. However, many complex chronic diseases exhibit large degrees of heterogeneity, and furthermore there is not always a single readily available biomarker to quantify disease severity. Eve…
DEBIAS learns causal effects from psychiatric longitudinal data by optimizing outcome weights.
problem Causal inference challenges in psychiatric longitudinal data due to symptom heterogeneity and latent confounding.
method DEBIAS algorithm that optimizes outcome weights to maximize durable treatment effects and minimize confounding.
result DEBIAS consistently outperforms state-of-the-art methods in recovering causal effects for clinically interpretable composite outcomes.
In this work we investigate intra-day patterns of activity on a population of 7,261 users of mobile health wearable devices and apps. We show that: (1) using intra-day step and sleep data recorded from passive trackers significantly improves classification performance on self-reported chronic conditions related to ment…
Much recent research aims to identify evidence for Drug-Drug Interactions (DDI) and Adverse Drug reactions (ADR) from the biomedical scientific literature. In addition to this "Bibliome", the universe of social media provides a very promising source of large-scale data that can help identify DDI and ADR in ways that ha…
Deep learning predicts drug prescriptions across global health records.
problem Predicting drug prescriptions in chronic disease patients.
method Adaptive cross-global attention graph kernel network with support vector machine.
result Model outperforms current methods in accuracy and interpretability.
Medical Knowledge Integration into Reinforcement Learning Algorithms for Dynamic Treatment Regimesstat.ME
RL algorithms with medical integration improve personalized treatment recommendations.
problem Developing effective personalized treatment strategies for chronic diseases.
method Integrating medical knowledge into RL algorithms for DTR.
result Enhanced treatment recommendations with increased confidence.
We study the behavior of a Time-Aware Long Short-Term Memory Autoencoder, a state-of-the-art method, in the context of learning latent representations from irregularly sampled patient data. We identify a key issue in the way such recurrent neural network models are being currently used and show that the solution of the…
Ensemble learning improves anomaly detection for milder symptoms.
problem Difficulty in detecting incipient anomalies due to similarity to normal conditions.
method Utilize uncertainty information from ensemble learning to identify misclassified incipient anomalies.
result Ensemble learning methods show improved performance on incipient anomaly detection.
This paper presents an example of how demographical characteristics of patients influence their susceptibility to certain medical conditions. In this paper, we investigate the association of health conditions to age of patients in a heterogeneous population. We show that besides the symptoms a patients is having, the a…
Smart bin monitors predict medication adherence with high accuracy.
problem Predicting chronic medication adherence to improve healthcare efficiency.
method Machine learning models trained on IoT device data.
result High predictive performance (ROC AUC 0.86).
Unstructured data refers to information that does not have a predefined data model or is not organized in a pre-defined manner. Loosely speaking, unstructured data refers to text data that is generated by humans. In after-sales service businesses, there are two main sources of unstructured data: customer complaints, wh…
In the presence of a layer of metaprobabilities (from uncertainty concerning the parameters), the asymptotic tail exponent corresponds to the lowest possible tail exponent regardless of its probability. The problem explains "Black Swan" effects, i.e., why measurements tend to chronically underestimate tail contribution…
ABC improves uncertainty quantification in LLMs for clinical diagnostics.
problem Overconfident and poorly calibrated estimates of LLMs in clinical domains.
method Approximate Bayesian Computation (ABC) for likelihood-free inference.
result Improves accuracy by up to 46.9%, reduces Brier scores by 74.4%, and enhances calibration.
Patient Risk Assessment and Warning Symptom Detection Using Deep Attention-Based Neural Networkscs.CL
We present an operational component of a real-world patient triage system. Given a specific patient presentation, the system is able to assess the level of medical urgency and issue the most appropriate recommendation in terms of best point of care and time to treat. We use an attention-based convolutional neural netwo…
Machine learning aids in diagnosing Parkinson's disease with higher accuracy.
problem Subjectivity in traditional PD diagnosis methods and missed early symptoms.
method Machine learning applied to various data modalities for PD and control group classification.
result Machine learning methods show high potential for improving PD diagnosis.
StageNet improves health risk prediction by integrating disease stage information.
problem Improving health risk prediction for patients with chronic conditions.
method StageNet uses a stage-aware LSTM and stage-adaptive convolutional modules to extract and integrate disease stage information.
result StageNet achieves up to 12% higher AUPRC for risk prediction and over 58% higher Calinski-Harabasz score for patient subtyping compared to state-of-the-art models.
Develops a two-stage conformal prediction method for Parkinson's disease medication needs.
problem Heterogeneous disease progression and treatment response in Parkinson's Disease.
method Two-stage conformal prediction framework with statistical guarantees.
result Quantifies uncertainty in medication needs predictions, improving clinical trust and quality of life.
Study reviews machine learning techniques for stress monitoring.
problem Improving accuracy of stress monitoring devices.
method Reviewed machine learning techniques for various stress indicators.
result Choosing the right classifier depends on multiple factors.
Identification of the influential clinical symptoms and laboratory features that help in the diagnosis of dengue fever in early phase of the illness would aid in designing effective public health management and virological surveillance strategies. Keeping this as our main objective we develop in this paper, a new compu…