Smart bin monitors predict medication adherence with high accuracy.
problem Predicting chronic medication adherence to improve healthcare efficiency.
method Machine learning models trained on IoT device data.
result High predictive performance (ROC AUC 0.86).
High quality risk adjustment in health insurance markets weakens insurer incentives to engage in inefficient behavior to attract lower-cost enrollees. We propose a novel methodology based on Markov Chain Monte Carlo methods to improve risk adjustment by clustering diagnostic codes into risk groups optimal for health ex…
Pediatric asthma is the most prevalent chronic childhood illness, afflicting about 6.2 million children in the United States. However, asthma could be better managed by identifying and avoiding triggers, educating about medications and proper disease management strategies. This research utilizes deep learning methodolo…
Managing patients with chronic diseases is a major and growing healthcare challenge in several countries. A chronic condition, such as diabetes, is an illness that lasts a long time and does not go away, and often leads to the patient's health gradually getting worse. While recent works involve raw electronic health re…
Proposes a new model for predicting chronic conditions over time.
problem Predicting complex relationships between multiple chronic conditions.
method Continuous time Bayesian network with adaptive regularization for structure and parameter learning.
result Proposed model provides sparse, intuitive representation of chronic condition relationships.
Chronicals boosts LLM fine-tuning speed by 3.51x over Unsloth.
problem Memory bottleneck in fine-tuning large language models.
method Four optimizations: fused kernels, cross-entropy reduction, LoRA+, and sequence packing.
result 3.51x speedup on A100-40GB with Qwen2.5-0.5B.
Purpose - Functional bowel diseases, including irritable bowel syndrome, chronic constipation, and chronic diarrhea, are some of the most common diseases seen in clinical practice. Many patients describe a range of triggers for altered bowel consistency and symptoms. However, characterization of the relationship betwee…
Simulation framework assesses ROI of chronic disease adherence and policy timing.
problem Uncertainty in ROI of adherence-enhancing interventions under heterogeneous patient behavior and socioeconomic variation.
method Simulation-based framework integrating disease progression, time-varying adherence, and policy timing.
result Early and adaptive interventions yield highest ROI, exceeding 20% under certain conditions.
New fair regression method improves fairness in chronic kidney disease classification.
problem Mitigating societal bias in health care for multiple groups.
method Penalized fair regression framework for multiple groups, with penalties for true positive rate disparity.
result Achieves fairness-accuracy frontier beyond existing methods in simulations and real-world data.
Bipolar disorder (BPD) is a chronic mental illness characterized by extreme mood and energy changes from mania to depression. These changes drive behaviors that often lead to devastating personal or social consequences. BPD is managed clinically with regular interactions with care providers, who assess mood, energy lev…
Enhances generative model for clinical data privacy and accuracy.
problem Data privacy in electronic patient records.
method Improves a time-series generative model with privacy safeguards.
result DP-TimeGAN achieves a mean authenticity of 0.778 on the CKD dataset.
Study uses machine learning and survival analysis to predict CKD progression.
problem Early detection and management of CKD to reduce ESRD risk.
method Combines machine learning and classical statistical models to identify novel CKD progression predictors.
result Deep learning models outperform other methods in predicting CKD progression.
Novel framework detects CKD in diabetic patients using sparse EHR representations.
problem Early detection of CKD in diabetic patients.
method Sparse longitudinal representations of EHR data.
result Proposed model achieves higher predictive performance than baselines.
Machine learning predicts obesity causes using genetic and imaging data.
problem Predicting causes of obesity in children and adults.
method Use ML techniques like decision trees, SVM, RF, GBM, LASSO, BN, and ANN on genetic and imaging data.
result ML models accurately predict obesity causes and chronic diseases.
Prediction of the future trajectory of a disease is an important challenge for personalized medicine and population health management. However, many complex chronic diseases exhibit large degrees of heterogeneity, and furthermore there is not always a single readily available biomarker to quantify disease severity. Eve…
In this work we investigate intra-day patterns of activity on a population of 7,261 users of mobile health wearable devices and apps. We show that: (1) using intra-day step and sleep data recorded from passive trackers significantly improves classification performance on self-reported chronic conditions related to ment…
Deep learning predicts drug prescriptions across global health records.
problem Predicting drug prescriptions in chronic disease patients.
method Adaptive cross-global attention graph kernel network with support vector machine.
result Model outperforms current methods in accuracy and interpretability.
RL algorithms with medical integration improve personalized treatment recommendations.
problem Developing effective personalized treatment strategies for chronic diseases.
method Integrating medical knowledge into RL algorithms for DTR.
result Enhanced treatment recommendations with increased confidence.
The paper addresses ill-conditioning in large spatial data, proposing solutions for prediction and likelihood estimation.
problem Ill-conditioning of the kernel matrix in large spatial data sets.
method Introduction of various optimality criteria and solutions for managing large spatial data.
result Solutions for managing large spatial data, addressing ill-conditioning and improving prediction and likelihood estimation.
We study the behavior of a Time-Aware Long Short-Term Memory Autoencoder, a state-of-the-art method, in the context of learning latent representations from irregularly sampled patient data. We identify a key issue in the way such recurrent neural network models are being currently used and show that the solution of the…
New models automate support group formation in online health communities.
problem Challenges in traditional support group formation methods for scalability, static categorization, and insufficient personalization.
method Two novel machine learning models: gDMR and gSTM, integrating user content, demographics, and network data.
result Models outperform baselines in predictive accuracy, semantic coherence, and internal group consistency.
In the presence of a layer of metaprobabilities (from uncertainty concerning the parameters), the asymptotic tail exponent corresponds to the lowest possible tail exponent regardless of its probability. The problem explains "Black Swan" effects, i.e., why measurements tend to chronically underestimate tail contribution…
MCGDiff uses SGM to guide SMC for solving ill-posed linear inverse problems.
problem Solving ill-posed linear inverse problems in Bayesian settings.
method Exploiting SGM structure, defining a sequence of intermediate problems, and using SMC methods.
result MCGDiff outperforms competing methods in Bayesian ill-posed inverse problems.
Scalable method completes ill-conditioned matrices from few samples.
problem Matrix completion from few samples for ill-conditioned matrices.
method Iterative algorithm combining IRLS, smoothing Newton, and proximal gradient methods.
result Local quadratic convergence rate and well-conditioned linear systems.
Study reviews machine learning techniques for stress monitoring.
problem Improving accuracy of stress monitoring devices.
method Reviewed machine learning techniques for various stress indicators.
result Choosing the right classifier depends on multiple factors.
Paper optimizes estimation of quadratic functionals in nonparametric IV models.
problem Optimal estimation of a nonlinear functional in ill-posed inverse regression.
method Adaptive, minimax estimation using leave-one-out, sieve NPIV estimator with data-driven sieve dimension selection.
result Adaptive estimator achieves minimax optimal rate in various ill-posed cases.
Improves numerical solution of ill-conditioned linear systems for machine learning.
problem Wastefulness and instability in solving ill-conditioned linear systems.
method autonugget combines Richardson extrapolation to determine the solution of the ill-conditioned system, improving accuracy over a single nugget.
result Improves accuracy of numerical solution of ill-conditioned linear systems.
Paper explores challenges in training PINNs and loss landscape effects.
problem Challenges in training Physics-Informed Neural Networks (PINNs) due to loss landscape issues.
method Examined gradient-based optimizers Adam, L-BFGS, and their combination Adam+L-BFGS, and introduced NysNewton-CG (NNCG).
result Adam+L-BFGS outperforms other optimizers, and NysNewton-CG significantly improves PINN performance.
SAPPHIRE tackles ill-conditioned rERM problems with faster convergence.
problem Ill-conditioned objectives and non-smooth regularizers in rERM.
method Sketch-based preconditioning and scaled proximal mapping.
result Achieves condition-number-free linear convergence.
Sufficient physical activity and restful sleep play a major role in the prevention and cure of many chronic conditions. Being able to proactively screen and monitor such chronic conditions would be a big step forward for overall health. The rapid increase in the popularity of wearable devices provides a significant new…
New framework assesses regularization norms in ill-posed problems, revealing L2 instability and proposing adaptive fractional RKHS solutions.
problem Comparative analysis of regularization norms in ill-posed problems.
method Small noise analysis framework for Tikhonov and RKHS regularizations.
result Optimal convergence rates achieved with adaptive fractional RKHS, but hyper-parameters decay too fast.
This paper develops explainable treatment policies for RPM using clinical knowledge.
problem Barriers to adoption of DHIs and lack of interpretability in purely black-box algorithms.
method Developed a pipeline for learning explainable treatment policies using clinician-informed representations.
result Policies learned from clinician-informed representations are more efficacious and efficient than black-box policies.
FINs enhance performance in diverse datasets like finance, speech, and health.
problem Improving neural network performance across various domains.
method Feature Imitating Networks (FINs) initialize weights to approximate specific statistical features.
result FINs significantly improve performance in Bitcoin price prediction, speech emotion recognition, and chronic neck pain detection.
A method learns representations for conditional moment models with controlled ill-posedness.
problem Efficient estimation of nonparametric conditional moment models with flexible models is challenging.
method Proposes a procedure that learns spectral representations with controlled measures of ill-posedness.
result The proposed method can efficiently estimate representations from data and is L2 consistent.
Perturbation theory improves nonparametric instrumental variable estimation accuracy.
problem Improving nonparametric instrumental variable estimation accuracy in high-dimensional settings.
method Perturbative approach based on physics perturbation theory, extending kernel ridge methods with higher-order corrections.
result First-order perturbative corrections reduce prediction error by up to 99% in high-dimensional ill-defined cases.
We developed an explainable artificial intelligence (AI) early warning score (xAI-EWS) system for early detection of acute critical illness. While maintaining a high predictive performance, our system explains to the clinician on which relevant electronic health records (EHRs) data the prediction is grounded. Acute cri…
A method models continuous-time glucose distributions in children with diabetes.
problem Capturing subtle temporal changes in glucose distributions.
method Probabilistic framework using Gaussian mixtures and neural ODEs.
result Detects treatment-related improvements in glucose dynamics.
Clinical researchers use disease progression models to understand patient status and characterize progression patterns from longitudinal health records. One approach for disease progression modeling is to describe patient status using a small number of states that represent distinctive distributions over a set of obser…
New framework uses score-based priors to solve ill-conditioned polynomial equations, improving signal recovery from noisy data.
problem Recovering signals from low-order moments in inverse problems, especially ill-conditioned polynomial equations.
method Integrates score-based diffusion priors with moment-based estimators to regularize and solve nonlinear inverse problems.
result Diffusion priors improve recovery from third-order moments and make super-resolution MTD feasible.
In the present paper we consider application of overcomplete dictionaries to solution of general ill-posed linear inverse problems. In the context of regression problems, there has been enormous amount of effort to recover an unknown function using such dictionaries. One of the most popular methods, lasso and its versi…
The Fredholm integral equation of the first kind improves solutions for ill-posed supervised learning problems with limited data.
problem Ill-posed supervised learning problems with insufficient data.
method Using the Fredholm integral equation of the first kind (FIFK) with semi-supervised assumptions and MSDF methods.
result Improved accuracy and stability in solutions for ill-posed problems.
Paper uses stats to predict treatment choice based on illness probability.
problem Improving treatment decision-making in personalized medicine.
method Statistical decision theory with maximum regret evaluation.
result Estimates illness probability for better treatment choice.
This paper analyzes adaptive gradient algorithms for better performance in ill-conditioned problems.
problem Poor performance of standard stochastic gradient algorithms in ill-conditioned problems.
method Non-asymptotic analysis of adaptive gradient algorithms (Adagrad and Stochastic Newton) for strongly convex objectives.
result Theoretical analysis and adaptation to practical applications like linear regression and regularized GLM.
Personalized predictive medicine necessitates the modeling of patient illness and care processes, which inherently have long-term temporal dependencies. Healthcare observations, recorded in electronic medical records, are episodic and irregular in time. We introduce DeepCare, an end-to-end deep dynamic neural network t…
Study describes severe dengue ICU patients in Brazil, 2012-2024.
problem Characterize severe dengue ICU patients and identify risk factors.
method Prospective study, descriptive statistics, logistic regression, machine learning.
result Advanced age, comorbidities, leukocytes, and platelets are significant risk factors for complications.
Improved convergence for overparameterized low-rank matrix sensing.
problem Overparameterized low-rank matrix sensing with unknown rank and ill-conditioning.
method ScaledGD(λ) - preconditioned gradient descent method. result ScaledGD(λ) converges at a constant linear rate after a logarithmic number of iterations. Respiratory infections and chronic respiratory diseases impose a heavy health burden worldwide. Coughing is one of the most common symptoms of many such infections, and can be indicative of flare-ups of chronic respiratory diseases. Whether at a clinical or public health level, the capacity to identify bouts of coughin…
Modeling disease progression in healthcare administrative databases is complicated by the fact that patients are observed only at irregular intervals when they seek healthcare services. In a longitudinal cohort of 76,888 patients with chronic obstructive pulmonary disease (COPD), we used a continuous-time hidden Markov…