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arXiv research

A locally-built, LLM-digested index of recent arXiv papers in quant finance, geometry/topology, and statistical ML — keyword search served straight from SQLite on this machine.

168,742 papers · 148 categories

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16334965 · Apr 202019922001200920172026
48 results for cell segmentation

We study the problem of instance segmentation in biological images with crowded and compact cells. We formulate this task as an integer program where variables correspond to cells and constraints enforce that cells do not overlap. To solve this integer program, we propose a column generation formulation where the prici…

2017-09-21abs ↗pdf ↗

This study automates blood cell classification using computer vision.

problem Automated detection and classification of white blood cells.
method Color-based segmentation, morphological processing, feature extraction, PCA, Unsupervised and Supervised learning algorithms, Deep Convolutional Neural Networks.
result Identification of robust algorithms for automated blood cell classification.

We introduce a novel Deep Learning framework, which quantitatively estimates image segmentation quality without the need for human inspection or labeling. We refer to this method as a Quality Assurance Network -- QANet. Specifically, given an image and a `proposed' corresponding segmentation, obtained by any method inc…

2019-04-09abs ↗pdf ↗

This paper provides a stratification of semi-algebraic sets in the plane with finitely many geodesic segments.

problem How to stratify semi-algebraic sets in the plane with finitely many geodesic segments.
method Develops a semi-algebraic stratification of a real semi-algebraic set in the plane with open cells having the finiteness property.
result Provides insights for high-dimensional stratifications of semi-algebraic sets in connection with geodesics.

Algorithm generates adaptive confidence sets for instance segmentation with guaranteed coverage.

problem Uncalibrated predictions and lack of uncertainty quantification in instance segmentation models.
method Conformal prediction algorithm to generate adaptive confidence sets with provable guarantees.
result Empirically, prediction sets vary in size based on query difficulty and attain target coverage, outperforming baselines.

Improves U-Net for scale equivariance in semantic segmentation.

problem Improving generalization in semantic segmentation tasks with varying scales.
method Introduces Scale Equivariant U-Net (SEU-Net) with carefully applied subsampling and upsampling layers and scale-equivariant layers.
result Significantly improved generalization to different scales compared to U-Net and scale-equivariant architecture without upsampling.

There are various algorithms and methodologies used for automated screening of cervical cancer by segmenting and classifying cervical cancer cells into different categories. This study presents a critical review of different research papers published that integrated AI methods in screening cervical cancer via different…

2018-11-02abs ↗pdf ↗

Determining the localization of specific protein in human cells is important for understanding cellular functions and biological processes of underlying diseases. Among imaging techniques, high-throughput fluorescence microscopy imaging is an efficient biotechnology to stain the protein of interest in a cell. In this w…

2019-01-27abs ↗pdf ↗

DVNet efficiently segments large neurovascular datasets using skip connections.

problem Challenges in segmenting large neurovascular datasets from high-throughput microscopy data.
method A fully-convolutional, deep, and densely-connected encoder-decoder network with skip connections.
result DVNet achieves superior performance in semantic segmentation of neurovascular datasets.

Analysis of flow cytometry data is an essential tool for clinical diagnosis of hematological and immunological conditions. Current clinical workflows rely on a manual process called gating to classify cells into their canonical types. This dependence on human annotation limits the rate, reproducibility, and complexity …

2017-11-21abs ↗pdf ↗

C2G-Net improves image classification of similar objects like cells.

problem Classifying images with many similar objects efficiently and interpretably.
method Combines image compression and a CNN with reduced parameters.
result C2G-Net achieves similar accuracy to conventional CNNs but with reduced training time and improved interpretability.

This paper proposes grid cells encode position via a conformal isometric embedding of 2D physical space.

problem Hexagonal grid firing patterns in grid cells.
method Learning a distance-preserving position embedding in neural space using a recurrent neural network.
result The conformal isometric embedding of 2D physical space into neural space explains hexagonal grid firing patterns.

The visual systems of many mammals, including humans, is able to integrate the geometric information of visual stimuli and to perform cognitive tasks already at the first stages of the cortical processing. This is thought to be the result of a combination of mechanisms, which include feature extraction at single cell l…

2014-07-02abs ↗pdf ↗

We consider polyhedra and 4-polytopes in Minkowski spacetime - in particular, null polyhedra with zero volume, and 4-polytopes that have such polyhedra as their hyperfaces. We present the basic properties of several classes of null-faced 4-polytopes: 4-simplices, "tetrahedral diamonds" and 4-parallelotopes. We propose …

2012-12-12abs ↗pdf ↗

Generative models have achieved impressive results in many domains including image and text generation. In the natural sciences, generative models have led to rapid progress in automated drug discovery. Many of the current methods focus on either 1-D or 2-D representations of typically small, drug-like molecules. Howev…

2019-09-03abs ↗pdf ↗

New algorithm for computing Veech groups from translation surfaces.

problem Computing Veech groups for translation surfaces.
method Infinite translation surface containing copies of all surfaces in a stratum; associated affine automorphisms of the infinite surface map marked segments to other pairs of segments.
result Explicit hyperbolic ball condition for Fuchsian groups to agree with their Dirichlet domain.

This study reviews and evaluates clustering methods for single-cell RNA-seq data.

problem Identifying and characterizing novel cell types from single-cell RNA-seq data.
method Review and performance comparison of clustering methods.
result Performance comparison experiments on two datasets.

Forest Fire Clustering discovers cell types from single-cell data.

problem Discovering cell types from large-scale single-cell sequencing data.
method Iterative label propagation and parallelized Monte Carlo simulation.
result Forest Fire Clustering outperforms state-of-the-art methods on diverse benchmarks.

Proposes CCCVAE for better single-cell clustering with cell-cell communication.

problem Improving single-cell RNA sequencing clustering by incorporating cell-cell communication.
method Integrates cell-cell communication into a variational autoencoder framework.
result Empirical results show CCCVAE outperforms standard VAEs in clustering performance.

Matching cells over time has long been the most difficult step in cell tracking. In this paper, we approach this problem by recasting it as a classification problem. We construct a feature set for each cell, and compute a feature difference vector between a cell in the current frame and a cell in a previous frame. Then…

2012-07-13abs ↗pdf ↗

Improved GPLVM model for single-cell RNA-seq data.

problem Lack of effective scalable models for clustering cell types in large-scale single-cell RNA-seq data.
method Introduces amortized stochastic variational Bayesian GPLVM (BGPLVM) tailored for single-cell RNA-seq.
result Matches the performance of scVI on synthetic and real-world datasets and reveals more interpretable latent structures.

The study identifies all possible vector field structures on specific 2D shapes.

problem Optimal discrete gradient vector fields on surfaces with 1-2 critical cells.
method Analysis of discrete vector fields on 2D shapes with minimal critical cells.
result All possible structures of discrete Morse functions on specified shapes.

New model identifies cell-specific genes for cancer prognosis.

problem No statistical model to integrate multiscale cancer data.
method Bayesian generalized promotion time cure models (GPTCMs).
result Improves cancer prognosis by identifying cell-specific genes.

MarkerMap selects key genes for cell type analysis in single-cell RNA-seq.

problem Selecting informative genes from large single-cell RNA-seq datasets is challenging and computationally intensive.
method MarkerMap is a generative model that identifies minimal gene sets explaining cell type variability.
result MarkerMap outperforms existing methods in both supervised and unsupervised marker selection.

New metric scores perturbations across populations, not cells, improving model comparison.

problem Single-cell perturbation data overlaps, making per-cell accuracy unreliable.
method Average per-cell probability vectors over all cells of a perturbation to form a population profile and rank candidate perturbations.
result Classifier Discrimination Score (CDS) identifies true perturbation more reliably than pseudobulk-based scores.

The process of morphogenesis, which can be defined as an evolution of the form of an organism, is one of the most intriguing mysteries in the life sciences. It is clear, that gene expression patterns cannot explain the development of the precise geometry of an organism and its parts in space. Here, we suggest a set of …

2012-05-05abs ↗pdf ↗

NESS improves neighbor embedding for smooth cell-state transitions in single-cell data.

problem Challenges in extracting smooth, low-dimensional representations from noisy single-cell data.
method Builds on PCS framework to develop NESS, a stable machine learning approach.
result NESS consistently yields useful biological insights across diverse single-cell datasets.

New model clusters cells and individuals, revealing genetic influences on cell types.

problem Clustering nested data with group-level and observation-level variables.
method Nested Atoms Model (NAM), Bayesian nonparametric approach.
result Identifies clusters of genetically similar individuals with homogeneous cell-type profiles.