Proposes CCCVAE for better single-cell clustering with cell-cell communication.
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Bayesian approach for multivariate density regression of complex data.
MarkerMap selects key genes for cell type analysis in single-cell RNA-seq.
New method learns cell trajectories from multiple snapshots.
Accurately predicting drug responses to cancer is an important problem hindering oncologists' efforts to find the most effective drugs to treat cancer, which is a core goal in precision medicine. The scientific community has focused on improving this prediction based on genomic, epigenomic, and proteomic datasets measu…
We study collaborative machine learning (ML) across wireless devices, each with its own local dataset. Offloading these datasets to a cloud or an edge server to implement powerful ML solutions is often not feasible due to latency, bandwidth and privacy constraints. Instead, we consider federated edge learning (FEEL), w…
New features from early battery cycles predict lifetime with high accuracy.
Enabling cellular connectivity for drones introduces a wide set of challenges and opportunities. Communication of cellular-connected drones is influenced by 3-dimensional mobility and line-of-sight channel characteristics which results in higher number of handovers with increasing altitude. Our cell planning simulation…
Method learns cell interaction rules from individual trajectories.
New model detects communities in networks with signed, continuous weights.
Flow cytometry is a high-throughput technology used to quantify multiple surface and intracellular markers at the level of a single cell. This enables to identify cell sub-types, and to determine their relative proportions. Improvements of this technology allow to describe millions of individual cells from a blood samp…
Adversarial perturbations and RIS interaction vectors improve covert communication.
Understanding functional organization of genetic information is a major challenge in modern biology. Following the initial publication of the human genome sequence in 2001, advances in high-throughput measurement technologies and efficient sharing of research material through community databases have opened up new view…
Multi-connectivity is emerging as a promising solution to provide reliable communications and seamless connectivity for the millimeter-wave frequency range. Due to the blockage sensitivity at such high frequencies, connectivity with multiple cells can drastically increase the network performance in terms of throughput …
Learning modular structures which reflect the dynamics of the environment can lead to better generalization and robustness to changes which only affect a few of the underlying causes. We propose Recurrent Independent Mechanisms (RIMs), a new recurrent architecture in which multiple groups of recurrent cells operate wit…
Kernel testing compares cell states in single-cell data.
Cell detection and cell type classification from biomedical images play an important role for high-throughput imaging and various clinical application. While classification of single cell sample can be performed with standard computer vision and machine learning methods, analysis of multi-label samples (region containi…
Forest Fire Clustering discovers cell types from single-cell data.
Matching cells over time has long been the most difficult step in cell tracking. In this paper, we approach this problem by recasting it as a classification problem. We construct a feature set for each cell, and compute a feature difference vector between a cell in the current frame and a cell in a previous frame. Then…
Improved GPLVM model for single-cell RNA-seq data.
The study identifies all possible vector field structures on specific 2D shapes.
Deep learning models are growing, posing new mathematical challenges.
New model identifies cell-specific genes for cancer prognosis.
Proposes CXNs for neural network computations on cell complexes.
In recent years, the advances in single-cell RNA-seq techniques have enabled us to perform large-scale transcriptomic profiling at single-cell resolution in a high-throughput manner. Unsupervised learning such as data clustering has become the central component to identify and characterize novel cell types and gene exp…
New metric scores perturbations across populations, not cells, improving model comparison.
Cataloging the neuronal cell types that comprise circuitry of individual brain regions is a major goal of modern neuroscience and the BRAIN initiative. Single-cell RNA sequencing can now be used to measure the gene expression profiles of individual neurons and to categorize neurons based on their gene expression profil…
The process of morphogenesis, which can be defined as an evolution of the form of an organism, is one of the most intriguing mysteries in the life sciences. It is clear, that gene expression patterns cannot explain the development of the precise geometry of an organism and its parts in space. Here, we suggest a set of …
Hippocampal dentate granule cells are among the few neuronal cell types generated throughout adult life in mammals. In the normal brain, new granule cells are generated from progenitors in the subgranular zone and integrate in a typical fashion. During the development of epilepsy, granule cell integration is profoundly…
NESS improves neighbor embedding for smooth cell-state transitions in single-cell data.
New model clusters cells and individuals, revealing genetic influences on cell types.
Cell-based NAS search spaces are redundant and lack novelty.
For a finite family of 3-dimensional almost contact metric manifolds with closed the structure form is described a construction of an almost contact metric manifold, where the members of the family are building blocks - cells. Obtained manifold share many properties of cells. One of the more important are nullity c…
HSSE framework embeds single-cell RNA-seq data at multiple scales.
Researchers infer gene activity in dividing cells, accounting for protein inheritance and division history.
SimCD simultaneously clusters cells and identifies differential gene expression in scRNA-seq data.
Under what conditions is an edge present in a social network at time t likely to decay or persist by some future time t + Delta(t)? Previous research addressing this issue suggests that the network range of the people involved in the edge, the extent to which the edge is embedded in a surrounding structure, and the age…
Understanding cell identity is an important task in many biomedical areas. Expression patterns of specific marker genes have been used to characterize some limited cell types, but exclusive markers are not available for many cell types. A second approach is to use machine learning to discriminate cell types based on th…
MFM integrates multiple evolving populations using Wasserstein manifold flows.
Two simple homotopy equivalent 2-complexes K2 and L2 are related by an algebraic criterion of their corresponding presentations as stated in [HoMeSier]. Frank Quinn set it into a topological context (see [Qu1]) and call these 2-complexes related by an s-move. Using elementary 3-expansions, K2 extends to 3-cells in K3 r…
We construct a small regular cellular decomposition of the Fulton MacPherson operad that is compatible with the operad composition. The cells are indexed by trees with edges of two colors and vertices labelled by cells of the cacti operad. We compute the generating functions counting the cells, that are algebrai…
Study homology of periodic cell complexes using quotient spaces and spectral sequences.
Recurrent neural networks (RNNs) were designed for dealing with time-series data and have recently been used for creating predictive models from functional magnetic resonance imaging (fMRI) data. However, gathering large fMRI datasets for learning is a difficult task. Furthermore, network interpretability is unclear. T…
Despite fluorescent cell-labelling being widely employed in biomedical studies, some of its drawbacks are inevitable, with unsuitable fluorescent probes or probes inducing a functional change being the main limitations. Consequently, the demand for and development of label-free methodologies to classify cells is strong…
The moduli space of Riemann surfaces with at least two punctures can be decomposed into a cell complex by using a particular family of ribbon graphs called Nakamura graphs. We distinguish the moduli space with all punctures labelled from that with a single labelled puncture. In both cases, we describe a cell decomposit…
Neural network predicts electrochemical cell faults with 53% less error.
New system constructs cell-type taxonomy across multiple samples.
Generalising a seminal result of Epstein and Penner for cusped hyperbolic manifolds, Cooper and Long showed that each decorated strictly convex projective cusped manifold has a canonical cell decomposition. Penner used the former result to describe a natural cell decomposition of decorated Teichmüller space of puncture…