Extends causal inference to hidden mediators with proxies.
problem Identifying causal effects with hidden mediators and error-prone proxies.
method Established causal hidden mediation analysis and hidden front-door criterion.
result Identification of population intervention indirect effect possible with hidden mediators.
Study compares estimators for causal mediation analysis with multiple mediators.
problem Estimating causal effects through multiple mediators in observational studies.
method Parametric and non-parametric estimators, including multiply robust and double machine learning approaches.
result Advanced estimators perform well across various settings and real data.
MediEncoder learns nonlinear representations for causal mediation analysis.
problem High-dimensional noisy covariates and mediators in biomedical studies.
method Coupled encoder-decoder architecture with cross-factor network.
result Improves estimation accuracy in high-dimensional causal mediation analysis.
It becomes increasingly popular to perform mediation analysis for complex data from sophisticated experimental studies. In this paper, we present Granger Mediation Analysis (GMA), a new framework for causal mediation analysis of multiple time series. This framework is motivated by a functional magnetic resonance imagin…
Proposes new method to handle hidden confounders in causal mediation analysis.
problem Break down total effect of treatment on outcome through different causal pathways.
method Combines proxy strategies and deep learning to uncover latent variables and estimate causal effects.
result Validated effectiveness of the proposed method for causal fairness analysis.
Tests whether a treatment's effect is fully mediated by observed outcomes and identifies causal mechanisms.
problem Understanding how a treatment affects an outcome through intermediate variables.
method Proposes a test to evaluate full mediation and causal mechanism identification, extending to non-randomly assigned treatments.
result A conditionally random treatment is conditionally independent of the outcome given mediators and covariates if full mediation and causal mechanism identification hold.
A new RL framework evaluates dynamic mediation effects over time.
problem Dynamic mediation effects in sequentially assigned treatments.
method Reinforcement Learning framework for decomposition and estimation of causal effects.
result Superior performance demonstrated through numerical studies and real data analysis.
New method stabilizes IF-based estimators for causal mediation analysis with continuous mediators.
problem Stability issues in IF-based estimators for continuous mediators.
method Nonparametric weighted balancing method to estimate nuisance functions.
result Significant reductions in bias and variance compared to existing methods.
The paper addresses causal mediation analysis with post-treatment events, proposing robust estimators and efficient methods.
problem Assessing causal mediation in the presence of post-treatment events like noncompliance or clinical events.
method Identifies natural mediation effects for entire populations and principal strata, derives efficient influence functions, and proposes multiply robust estimators.
result Multiply robust estimators are consistent under four types of misspecifications and efficient when all models are correct.
DeepMed uses DNNs to estimate causal mediation effects without sparsity constraints.
problem Estimating Natural Direct and Indirect Effects in mediation analysis.
method DeepMed employs deep neural networks to cross-fit infinite-dimensional nuisance functions.
result DeepMed achieves semiparametric efficiency bound and adapts to low-dimensional nuisance structures.
New method handles indirect mediators in CMA for complex scenarios.
problem Handling indirect and multi-dimensional mediators in causal mediation analysis.
method Identifiable Variational Autoencoder (iVAE) architecture for multi-dimensional, indirectly observed mediators.
result Accurate estimation of direct and mediated effects in synthetic and semi-synthetic experiments.
Paper proposes a machine learning-based method for estimating mediation effects.
problem Challenges in estimating mediation effects with multiple, continuous mediators.
method Developed a one-step estimation algorithm using machine learning and Riesz learning.
result Proposed method can estimate mediation effects from just two statistical estimands.
DCMA uses generative models to analyze treatment effects on entire outcome distributions.
problem Traditional mediation analysis focuses on summary contrasts, missing complex distributional changes.
method DCMA learns conditional generative models for mediators and outcome, reconstructing interventional distributions via Monte Carlo simulation.
result DCMA captures both summary effects and rich distributional contrasts like energy distance and Wasserstein distance.
A new DML method for continuous treatments uncovers causal mediation effects.
problem Estimating causal mediation effects with continuous treatments.
method Double machine learning (DML) algorithm using kernel-based doubly robust moment function.
result Asymptotic normality with nonparametric convergence rate for estimating mediated response curve.
DCMA uses generative models to analyze complex treatment effects on outcome distributions.
problem Analyzing complex and nonlinear causal mechanisms through outcome-level summary contrasts.
method Generative learning framework for identifying and estimating treatment effects on entire outcome distributions.
result Reconstructs interventional outcome distributions via Monte Carlo forward simulation, capturing both summary and distributional contrasts.
Study introduces a new method to estimate causal mediation with multiple mediators.
problem Estimating causal effects with multiple mediators and confounders.
method Simulates potential outcomes using parametric and nonparametric models.
result General approach to estimating various causal mediation quantities.
A method combines deep learning and G-estimation for causal mediation analysis.
problem Estimating structural mediation parameters under unmeasured confounding.
method UNIT method using TARNet for representation learning and G-estimation.
result Improved precision of structural parameter estimator through better representation learning.
The paper identifies the best treatment to maximize NDPO, a key outcome in causal mediation analysis.
problem Identifying the treatment that maximizes the expected natural direct potential outcome (NDPO) in causal mediation analysis.
method Developed a fixed-confidence best-arm identification (BAI) algorithm based on the Track-and-Stop (TaS) framework, using a cutting-set method to solve a semi-infinite optimization problem.
result The proposed algorithm achieves sample-efficient identification with a high-probability correctness guarantee and asymptotic optimality.
Summary statistics of genome-wide association studies (GWAS) teach causal relationship between millions of genetic markers and tens and thousands of phenotypes. However, underlying biological mechanisms are yet to be elucidated. We can achieve necessary interpretation of GWAS in a causal mediation framework, looking to…
Develops a new density ratio estimator for causal inference.
problem Estimation of density ratio functions in statistics.
method Super learning approach with a novel loss function.
result Empirical validation of the density ratio super learner's performance.
Proposes a new estimator for causal mediation with continuous treatments.
problem Estimation of direct and indirect effects with continuous treatments.
method Kernel smoothing approach with cross-fitting for non-parametric estimation.
result Multiply robust and asymptotically normal estimator for continuous treatments.
New methods estimate causal effects through mediators, handling confounding without strict assumptions.
problem Estimating causal effects through mediators while accounting for unmeasured confounding.
method Developed four nonparametric identification strategies using proximal confounding bridge functions, efficient influence function, and quadruply robust estimator. Proposed proximal debiased machine learning approach for high-dimensional nuisance parameters.
result Achieved n \sqrt{n} n -consistency and asymptotic normality for path-specific effect estimation. Proximal Mediation Analysis with Hidden Recanting Witnesses
problem Identifying path-specific effects in mediation analysis when recanting witnesses are unknown
method Proximal causal inference and semiparametric inference framework
result Developed three novel identification strategies and a semiparametric inference framework
Unified framework for estimating indirect effects in observational studies with unmeasured confounding.
problem Challenges in evaluating indirect effects due to unmeasured confounding and unethical exposures.
method Developed a unified identification and estimation framework using proximal causal inference.
result Unified identification and estimation of PIIE and causal effect of an intervening variable in settings with pervasive unmeasured confounding.
Study relaxes identification assumptions for natural direct effects in non-randomized settings.
problem Identifying causal direct effects under unmeasured confounding.
method Developed relaxed conditions for identifying natural direct effects in non-randomized settings.
result Identified natural direct effect under unmeasured confounding conditions.
In many scientific studies, it becomes increasingly important to delineate the causal pathways through a large number of mediators, such as genetic and brain mediators. Structural equation modeling (SEM) is a popular technique to estimate the pathway effects, commonly expressed as products of coefficients. However, it …
The paper compares and optimizes estimators for treatment effects with observed confounders and mediators.
problem Estimating treatment effects with observed confounders and mediators.
method Investigates the linear Gaussian causal model, compares and optimizes estimators, and combines datasets.
result An optimal estimator outperforms the backdoor and frontdoor estimators by an unbounded constant factor.
Develops tools to decompose spurious variations in causal models.
problem Understanding and decomposing spurious variations in causal relationships.
method Formal tools for decomposing spurious effects in Markovian and Semi-Markovian models.
result First results on non-parametric decomposition of spurious effects and sufficient conditions for identification.
Method for understanding heterogeneous treatment effects in complex causal graphs.
problem Heterogeneity and comorbidity in healthcare problems.
method Developed a new approach to characterize heterogeneous causal effects (HCEs) in graphical contexts, including heterogeneous causal graphs (HCGs) with confounders and mediators.
result Established theoretical forms and properties of HCEs in linear and nonlinear models, and developed interactive structural learning for estimation.
New method analyzes complex multivariate pathways in high-dimensional data.
problem High-dimensional mediation analysis of multivariate exposures, mediators, and outcomes.
method Simultaneous variable selection, indirect effect matrix estimation, and prediction of multivariate outcomes.
result Identifies biologically interpretable genetic-neural-cognitive pathways.
The goal of personalized decision making is to map a unit's characteristics to an action tailored to maximize the expected outcome for that unit. Obtaining high-quality mappings of this type is the goal of the dynamic regime literature. In healthcare settings, optimizing policies with respect to a particular causal pat…
We consider the problem of identifying intermediate variables (or mediators) that regulate the effect of a treatment on a response variable. While there has been significant research on this classical topic, little work has been done when the set of potential mediators is high-dimensional (HD). A further complication a…
PESCAL uses mediators to learn from confounded offline data.
problem Learning from confounded observational data in reinforcement learning.
method PESCAL uses mediator variables and the pessimistic principle to address confounding bias and distributional shift.
result It is sufficient to learn a lower bound of the mediator distribution function to mitigate distributional shift.
A method to assess sensitivity to unmeasured confounding with sharp bounds.
problem Assessing the impact of unmeasured confounding on causal effects.
method Sets two intuitive parameters to estimate sensitivity intervals.
result Bounds on true causal effects can be tighter than existing methods.
Contrastive learning harms minority group representations, affecting downstream tasks.
problem Representation harm in contrastive learning, especially affecting minority groups.
method Causal mediation analysis and stochastic block model explanation.
result Representation harm in contrastive learning is partly responsible for allocation harm in downstream tasks.
Proposes a framework for causal inference with processed outcomes in biomedical research.
problem Impact of intra-subject processing on inter-subject statistical inference in biomedical research.
method Semiparametric framework with multiply robust estimators and step-down procedure for high-dimensional inference.
result Superior performance of the proposed approach demonstrated through simulations and application to autism research.
Framework trains safe agents avoiding deceptive behavior.
problem Training safe agents from unsafe incentives.
method Formal settings, causal influence analysis, maximizing non-mediated effects.
result Agents avoid manipulating delicate state for rewards.
Debiased learners estimate heterogeneous treatment effects in observational studies.
problem Estimating heterogeneous treatment effects in observational studies with unmeasured confounders.
method Debiased Front-Door (FD) learners, FD-DR-Learner and FD-R-Learner, under specific assumptions.
result Debiased learners satisfy error bounds and stage-error decompositions, delivering reliable HTE estimates.
New method reduces bias in estimating causal effects from discretized variables.
problem Bias in estimating causal effects from discretized continuous variables.
method Proposes a bias-reduced functional that evaluates outcome regression at within-bin conditional means.
result Demonstrates substantial bias reduction and near-nominal confidence interval coverage.
New approach for estimating individual treatment effects in low compliance settings.
problem Estimating individual treatment effects in scenarios with low compliance.
method Proposes a new approach using Structural Causal Model and do-calculus to estimate Individual Prescription Effect (IPE) with asymptotic variance guarantees.
result Consistently improves state-of-the-art in low compliance settings.
New methods for estimating complex causal effects in econometrics.
problem Estimating causal parameters in short panel data models using nested nonparametric instrumental variable regression.
method Introducing techniques to limit ill-posedness in nested NPIV, providing explicit mean square rates and efficient inference.
result Explicit mean square rates for nested NPIV and efficient inference for causal parameters.
Estimates causal effects using machine learning for binary treatment and mediator.
problem Estimating direct and indirect quantile treatment effects under selection-on-observables.
method Double/debiased machine learning estimators based on efficient score functions.
result Uniform consistency and asymptotic normality of effect estimators.
Temporal Causal Prior-Data Fitted Networks (TCPFN) for industrial time series causal discovery
problem Estimating causal effects in industrial time series
method Temporal Causal Prior-Data Fitted Networks
result Zero-shot causal discovery with explicit reliability signals
New methods identify causal effects without needing complete proxy variables.
problem Identifying causal effects in the presence of unmeasured confounders.
method Partial identification methods that do not require completeness of proxy variables.
result Obtain bounds on causal effects using available proxy variables.
New methods estimate causal effects using front-door criterion in presence of unmeasured confounders.
problem Estimating causal effects in observational studies with unmeasured confounders.
method Developed novel one-step and targeted minimum loss-based estimators for front-door assumptions.
result Established conditions for root-n consistency and asymptotic linearity.
Proposes estimators for complex dose-response curves using kernel methods.
problem Estimating complex dose-response curves with continuous treatments, mediators, and covariates.
method Kernel ridge regression with sequential kernel embedding technique.
result Simple estimators for mediated and time-varying dose response curves with nonasymptotic uniform rates.
Study reveals dynamic causal relationships between Ethereum transaction fees and economic subsystems.
problem Historical gas fee volatility caused economic disequilibria and stakeholder challenges.
method Time-varying Granger causality analysis using data on active wallets and transaction volume.
result Dynamic bidirectional causal relationships between transaction fees and economic subsystems across Ethereum.
Study finds racial bias in pulse oximeter readings has minimal impact on ICU ventilation rates.
problem Racial disparities in pulse oximeter readings affect clinical decisions in ICU settings.
method Causal inference using path-specific effects and doubly robust estimator.
result Minimal impact of racial discrepancies on invasive ventilation rates, but more pronounced on ventilation duration.