Deep neural network predicts cardiac shape from MRI images and patient data.
problem Automatic 3D cardiac shape analysis for large-scale studies.
method Uses deep neural networks combining MRI images and patient metadata.
result Significant agreement with reference shapes in cardiac parameters.
Cardiac motion modeling using LDDMM and shape splines.
problem Difficulties in probing cardiac function due to shape and deformation interactions.
method LDDMM framework, parallel transport, normalization, shape splines.
result Significant differences in model parameters between pathologies, revealing insights into disease dynamics.
We propose a method to classify cardiac pathology based on a novel approach to extract image derived features to characterize the shape and motion of the heart. An original semi-supervised learning procedure, which makes efficient use of a large amount of non-segmented images and a small amount of images segmented manu…
Radiomics approach improves cardiac CVD diagnosis from cine-MRI.
problem Inaccurate expert visualization or clinical indices for CVD classification.
method Estimating radiomic features from cine-MRI, feature selection, advanced machine learning.
result Radiomics features correctly classified 100 cases of five cardiac classes.
The exploitation of large-scale population data has the potential to improve healthcare by discovering and understanding patterns and trends within this data. To enable high throughput analysis of cardiac imaging data automatically, a pipeline should comprise quality monitoring of the input images, segmentation of the …
Study finds AI can predict diverse cardiac and non-cardiac diagnoses from a single ECG.
problem Narrow focus of ECG analysis models for diverse medical conditions.
method Exploratory study using a single AI model to predict multiple ICD codes.
result Model achieved AUROC scores > 0.8 for 253 cardiac and 172 non-cardiac diagnoses.
In the recent years, Riemannian shape analysis of curves and surfaces has found several applications in medical image analysis. In this paper we present a numerical discretization of second order Sobolev metrics on the space of regular curves in Euclidean space. This class of metrics has several desirable mathematical …
Left atrium shape has been shown to be an independent predictor of recurrence after atrial fibrillation (AF) ablation. Shape-based representation is imperative to such an estimation process, where correspondence-based representation offers the most flexibility and ease-of-computation for population-level shape statisti…
Study analyzes how blood pressure impacts cardiac health.
problem Impact of blood pressure on cardiac function.
method Combines deep learning and variational autoencoder for interpretable biomarkers.
result Identifies key factors and patterns of cardiac adaptation.
Enhanced deep CNNs improve cardiac abnormality diagnosis from ECGs.
problem Diagnosing cardiac abnormalities from 12-lead ECGs.
method Training an enhanced deep convolutional neural network with hand-crafted features, data preprocessing, and augmentation.
result Promising generalization performance in ECG diagnosis.
Proposes a hybrid deep learning network for better heart failure survival prediction.
problem Improving survival prediction in heart failure patients.
method Joint analysis of cardiac motion features and clinical risk factors using a hybrid deep learning network.
result Optimal integration of clinical risk factors into deep prediction networks.
Novel framework monitors cardiac image segmentation models in real-time.
problem Ensuring continuous high model performance and segmentation results in clinics.
method Formulated as anomaly detection, the framework derives surrogate quality measures for segmentation.
result Demonstrated accurate, fast, and scalable quality control monitoring.
Motion analysis is used in computer vision to understand the behaviour of moving objects in sequences of images. Optimising the interpretation of dynamic biological systems requires accurate and precise motion tracking as well as efficient representations of high-dimensional motion trajectories so that these can be use…
hyperSBINN improves drug cardiosafety assessment by efficiently modeling cardiac action potentials.
problem Complexity and limited data in modeling cardiac effects of drugs.
method Combining meta-learning with SBINNs to solve parameterized cardiac action potential models.
result hyperSBINN outperforms traditional solvers in speed and accuracy for predicting APD90 values.
The segmentation of the left ventricle (LV) from CINE MRI images is essential to infer important clinical parameters. Typically, machine learning algorithms for automated LV segmentation use annotated contours from only two cardiac phases, diastole, and systole. In this work, we present an analysis work-flow for fully-…
Radiomics identifies subtle cardiac changes in hypertension.
problem Subtle cardiac alterations in hypertension not captured by conventional imaging.
method Combines feature selection and machine learning for identifying structural and tissue changes.
result Radiomics model detects changes beyond conventional imaging.
GANs improve echo frame generation with labeled patches.
problem Automated echocardiography with limited labels.
method Conditional GAN with patch-based discriminator.
result GAN-enhanced echo frames match given segmentation masks.
CardiacGen generates realistic ECG signals for training deep learning models.
problem Creating realistic synthetic ECG signals for training deep learning models.
method Hierarchical deep generative model with multi-objective loss functions.
result Synthetic ECG signals from CardiacGen can be used for data augmentation and improve classifier performance.
Method identifies cardiac ectopic activity sites from 12-lead ECG.
problem Locate dangerous ectopic activation sites in the heart.
method Bayesian optimization on cardiac model and ECG data.
result Method converges to minimum after 11.7-3.5 iterations.
The paper uses geometric methods to classify medical data histograms.
problem Classifying medical data histograms for disease diagnosis.
method Information geometry of beta distributions for comparing and classifying histograms.
result Geometric tools, particularly negatively curved Fisher information, enable unique mean calculation and K-means classification.
Researchers use operator learning to predict cardiac activation and repolarization times.
problem Computational demands and need for clear, interpretable information in cardiac electrophysiology.
method Exploiting Fourier Neural Operators (FNO) and Kernel Operator Learning (KOL) to learn operator mappings.
result Both FNO and KOL approaches are computationally efficient and robust to hyperparameters.
We introduce a model-based reconstruction framework with deep learned (DL) and smoothness regularization on manifolds (STORM) priors to recover free breathing and ungated (FBU) cardiac MRI from highly undersampled measurements. The DL priors enable us to exploit the local correlations, while the STORM prior enables us …
Method synthesizes 4D CMR images from XCAT model using GAN and SPADE.
problem Synthesizing realistic 4D CMR images with annotations and adaptable styles.
method Hybrid GAN approach with XCAT anatomical ground truth and SPADE for semantic preservation.
result Synthesized images with modality-specific features learned from real CMR data.
This study benchmarks algorithms for automatic segmentation of LGE-MRI images of the left atrium.
problem Challenging segmentation of LGE-MRI images due to low contrast.
method Organized a large-scale benchmarking challenge with 154 3D LGE-MRIs and 27 teams.
result Top method achieved 93.2% dice score and 0.7 mm mean surface to surface distance.
Bayesian optimization on cardiac models using a graph convolutional VAE.
problem Optimizing tissue properties in cardiac models with spatially varying properties.
method Graph convolutional VAE for generative modeling of non-Euclidean data.
result Effective optimization of cardiac tissue properties using a novel generative model.
Performing inference over simulators is generally intractable as their runtime means we cannot compute a marginal likelihood. We develop a likelihood-free inference method to infer parameters for a cardiac simulator, which replicates electrical flow through the heart to the body surface. We improve the fit of a state-o…
Improved cardiac arrhythmia detection in wearable devices with neural networks.
problem Resource constraints in low-power wearable devices for accurate arrhythmia detection.
method Adapted a convolutional-recurrent neural network to a low-power microcontroller, optimizing for precision and memory usage.
result Reduced F1 score from 0.8 to 0.784 in fixed-point precision, with a 195.6KB memory footprint and 33.98MOps/s throughput. Objectives: Atrial fibrillation (AF) is a common heart rhythm disorder associated with deadly and debilitating consequences including heart failure, stroke, poor mental health, reduced quality of life and death. Having an automatic system that diagnoses various types of cardiac arrhythmias would assist cardiologists to…
CLOCS uses contrastive learning to improve cardiac signal representations.
problem Lack of labelled data in cardiac signal analysis.
method Contrastive learning across space, time, and patients.
result CLOCS outperforms state-of-the-art methods and achieves strong generalization.
Recent introduction of wearable single-lead ECG devices of diverse configurations has caught the intrigue of the medical community. While these devices provide a highly affordable support tool for the caregivers for continuous monitoring and to detect acute conditions, such as arrhythmia, their utility for cardiac diag…
Framework for imputing missing heart data to simulate brain-heart interactions.
problem Lack of multi-modal patient data representing heart and brain processes.
method Probabilistic framework for joint cardiac data imputation and mechanistic model personalization.
result Accurate imputation of missing cardiac features in incomplete datasets.
Causal analysis reveals regional discrepancies in TOPCAT trial results.
problem Inconclusive results in TOPCAT trial for heart failure treatment.
method Causal discovery methods with domain knowledge integration.
result Significant causal effects shown for some subgroups globally.
This paper is an attempt to separate cardiac and respiratory signals from an electrical bio-impedance (EBI) dataset. For this two well-known algorithms, namely Principal Component Analysis (PCA) and Independent Component Analysis (ICA), were used to accomplish the task. The ability of the PCA and the ICA methods first …
Deep learning models trained on adult cardiac MRI data struggle to accurately segment rare congenital heart diseases.
problem Accuracy of U-Net-based segmentation models trained on adult cardiac MRI data when applied to rare congenital heart diseases like Tetralogy of Fallot.
method Cross-validation with four-fold, evaluation on unseen data from different pathologies.
result Deep learning models overfit to the training data, leading to significant accuracy drops when applied to other pathologies.
Novel method embeds generative model into Bayesian optimization for HD cardiac model parameter estimation.
problem High-dimensional optimization of patient-specific cardiac model parameters with limited data.
method Embeds a generative variational auto-encoder into the objective function of Bayesian optimization.
result Improves accuracy of parameter estimation with more than 10x gain in efficiency.
Cardiovascular disease (CVD) is the global leading cause of death. A strong risk factor for CVD events is the amount of coronary artery calcium (CAC). To meet demands of the increasing interest in quantification of CAC, i.e. coronary calcium scoring, especially as an unrequested finding for screening and research, auto…
DRUM transfers cardiac arrest models across registries with missing covariates.
problem Clinical prediction models fail when key training covariates are unavailable at deployment.
method DRUM transfers models to target populations with structurally missing covariates, optimizing worst-case predictive performance over unknown target distributions.
result DRUM yields better-calibrated predictions and improved clinical classification performance across sites.
Study converts echocardiography views using adversarial models.
problem Limited information sharing among echocardiography views.
method Adversarial generative models trained with LSGAN, PatchGAN, and cGAN.
result Generated views correlate with real views in LV area and length.
Background: Cardiac MRI derived biventricular mass and function parameters, such as end-systolic volume (ESV), end-diastolic volume (EDV), ejection fraction (EF), stroke volume (SV), and ventricular mass (VM) are clinically well established. Image segmentation can be challenging and time-consuming, due to the complex a…
SoQal uses selective oracle questioning to improve active learning of cardiac signals.
problem Active learning of cardiac signals is challenging due to limited labelled data and high annotation costs.
method Proposes a framework combining selective oracle questioning and Bayesian active learning by consistency.
result SoQal outperforms baseline methods in active learning of cardiac signals, even with noisy oracles.
LU-Net improves cardiac segmentation accuracy and robustness.
problem Robustness and accuracy of deep learning cardiac segmentation.
method Multi-task end-to-end network designed to improve cardiac segmentation.
result Outperforms current best deep learning solution, reducing outliers and improving clinical indices.
Study builds models to predict post-cardiac arrest outcomes using patient data.
problem Lack of accurate prognostication methods for patients resuscitated from cardiac arrest.
method Integrated electronic health records (EHR) and physiological time series (PTS) data to train machine learning classifiers.
result Combined EHR-PTS24 models outperformed models using either EHR or PTS24 alone in predicting survival and neurological outcomes.
This study benchmarks changepoint detection algorithms on cardiac time series data.
problem Identifying state changes in cardiac time series for disease classification.
method Comparison of 8 changepoint detection algorithms on artificial and real cardiac time series data.
result RMDM algorithm achieved highest true positive rate and cross validated accuracy for classification.
Intricating cardiac complexities are the primary factor associated with healthcare costs and the highest cause of death rate in the world. However, preventive measures like the early detection of cardiac anomalies can prevent severe cardiovascular arrests of varying complexities and can impose a substantial impact on h…
The paper highlights the importance of model discrepancy in cardiac simulations.
problem Uncertainty in model structure and equations affects predictions.
method The authors use Gaussian processes and autoregressive-moving-average models to account for model discrepancy.
result Different methods to account for model discrepancy have advantages and shortcomings.
Anatomical and biophysical modeling of left atrium (LA) and proximal pulmonary veins (PPVs) is important for clinical management of several cardiac diseases. Magnetic resonance imaging (MRI) allows qualitative assessment of LA and PPVs through visualization. However, there is a strong need for an advanced image segment…
Manual segmentation of the Left Ventricle (LV) is a tedious and meticulous task that can vary depending on the patient, the Magnetic Resonance Images (MRI) cuts and the experts. Still today, we consider manual delineation done by experts as being the ground truth for cardiac diagnosticians. Thus, we are reviewing the p…
We review some of the latest approaches to analysing cardiac electrophysiology data using machine learning and predictive modelling. Cardiac arrhythmias, particularly atrial fibrillation, are a major global healthcare challenge. Treatment is often through catheter ablation, which involves the targeted localized destruc…