Estimates tumor growth parameters from MRI data.
problem Personalizing brain tumor growth models for individual patients.
method Learning-based technique using a mixture-density network to estimate parameters from medical scans.
result Reduces the number of forward model integrations and relaxes functional form constraints.
Gliomas are the most common primary brain malignancies, with different degrees of aggressiveness, variable prognosis and various heterogeneous histologic sub-regions, i.e., peritumoral edematous/invaded tissue, necrotic core, active and non-enhancing core. This intrinsic heterogeneity is also portrayed in their radio-p…
Brain tumor segmentation from Magnetic Resonance Images (MRIs) is an important task to measure tumor responses to treatments. However, automatic segmentation is very challenging. This paper presents an automatic brain tumor segmentation method based on a Normalized Gaussian Bayesian classification and a new 3D Fluid Ve…
The paper predicts brain tumor patient survival using segmentation and features.
problem Predicting overall survival of brain tumor patients.
method Automated brain tumor segmentation and use of age, shape, and volumetric features for prediction.
result Random forest classifier achieves 59% accuracy on test dataset and 67% on gross total resection dataset.
New method uses image-level and pixel-level annotations for brain tumor segmentation.
problem Challenges in obtaining pixel-level annotations for brain tumor segmentation.
method Proposes a learning-based framework that combines both pixel- and image-level annotations.
result Method's performance in segmentation quality is competitive with traditional fully-supervised approach.
The paper uses neural networks to segment brain tumors and predict patient survival.
problem Brain tumor segmentation and survival prediction.
method Fully convolutional neural network with encoder-decoder architecture, radiomic features, and random forest regression.
result 55.4% classification accuracy for predicting survival of patients with gross-total resection.
The paper explores methods to explain brain tumor segmentation models and extract visualizations.
problem Improving interpretability of deep learning models for brain tumor segmentation.
method Exploring techniques to explain brain tumor segmentation models and extract visualizations.
result Brain tumor segmentation networks learn human-understandable disentangled concepts and use a top-down approach.
RCS-YOLO improves brain tumor detection speed and accuracy.
problem Efficiently detecting brain tumors with high accuracy and speed.
method Proposes RCS-YOLO, a fast and accurate brain tumor detector using YOLO with Reparameterized Convolution and channel Shuffle.
result RCS-YOLO outperforms other YOLO versions in speed and accuracy on brain tumor detection.
In this work we approach the brain tumor segmentation problem with a cascade of two CNNs inspired in the V-Net architecture \cite{VNet}, reformulating residual connections and making use of ROI masks to constrain the networks to train only on relevant voxels. This architecture allows dense training on problems with hig…
Paper tackles brain tumor segmentation using weak labels and hierarchical training.
problem High manual labeling effort for fully supervised brain tumor segmentation.
method Uses scribbles and global labels for weak supervision, trains two networks in phases.
result Achieves competitive results on brain tumor segmentation and substructure segmentation.
In this paper we present a method for simultaneously segmenting brain tumors and an extensive set of organs-at-risk for radiation therapy planning of glioblastomas. The method combines a contrast-adaptive generative model for whole-brain segmentation with a new spatial regularization model of tumor shape using convolut…
TuNet improves glioma segmentation accuracy and efficiency.
problem Accurate and efficient glioma segmentation for early treatment.
method End-to-end cascaded network with hierarchical structure and ResNet-like blocks.
result Improved segmentation accuracy and reduced treatment costs.
Framework detects brain tumors robustly from MRI images.
problem Low clinical incidence of brain tumor cases makes diagnosis challenging.
method YOLOv8n for detection, DeiT for classification, PTP metric for evaluation.
result F1-score of 0.92 achieved with reduced computational resources.
Brain cancer can be very fatal, but chances of survival increase through early detection and treatment. Doctors use Magnetic Resonance Imaging (MRI) to detect and locate tumors in the brain, and very carefully analyze scans to segment brain tumors. Manual segmentation is time consuming and tiring for doctors, and it ca…
A method for MRI brain tumor segmentation using feature vectors and kernel dictionary learning.
problem Segmenting brain tumor regions in MRI images.
method Extracting feature vectors, training kernel dictionaries, and selecting informative feature vectors.
result The method outperforms other methods in segmentation accuracy and reduces training time.
Bayesian method transfers knowledge between brain tumor datasets.
problem Applying deep learning to small medical datasets.
method Generative Bayesian Prior network for knowledge transfer.
result Best results in Dice Similarity Coefficient for BRATS2018.
Bayesian method transfers knowledge between brain tumor datasets for MRI segmentation.
problem Limited applicability of deep learning methods for small medical datasets.
method Generative Bayesian Prior network for knowledge transfer.
result Best results in Dice Similarity Coefficient metric for BRATS2018.
SegAN-CAT improves brain tumor segmentation in MRI using adversarial networks.
problem Improving brain tumor segmentation accuracy in MRI.
method Adversarial Networks, transfer learning, single modality MRI.
result Transfer learning improves single modality MRI segmentation performance.
Global Planar Convolution boosts brain tumor segmentation by enhancing context perception.
problem Improving context perception in brain tumor segmentation networks.
method Introduced Global Planar Convolution module to enhance context aggregation in brain tumor segmentation.
result Global Planar Convolution eliminates the need for multiple representation levels in segmentation networks.
Deep learning improves brain tumor detection with few data.
problem Scarce training data and data corruption in medical diagnosis.
method Data distillation and augmentation to improve deep neural network training.
result Reaches human expert-level accuracy with just a few thousand training examples.
This paper analyzes the use of 3D Convolutional Neural Networks for brain tumor segmentation in MR images. We address the problem using three different architectures that combine fine and coarse features to obtain the final segmentation. We compare three different networks that use multi-resolution features in terms of…
Model improves covariance estimation from shared and distinct datasets.
problem Limited sample sizes and shared covariance structure across related datasets.
method Spiked covariance model with shared subspace, closed-form pooling weight, and asymptotic guarantees.
result Improves estimation of high-dimensional covariance matrices from related datasets.
EB-VAE combines tumor growth and dropout data for personalized treatment response modeling.
problem Challenges in integrating longitudinal tumor measurements, dropout information, and genetic covariates.
method Extended EB-VAE framework to jointly model longitudinal and time-to-event data, incorporating dropout hazard and genetic covariates.
result Hybrid decoder formulation yields consistent treatment-effect parameters and prior predictive performance comparable to neural decoder.
Most of the current state-of-the-art methods for tumor segmentation are based on machine learning models trained on manually segmented images. This type of training data is particularly costly, as manual delineation of tumors is not only time-consuming but also requires medical expertise. On the other hand, images with…
Unsupervised method selects genes for tumor subtype discovery.
problem High-dimensional tumor gene expression data with noisy variables and heterogeneity.
method Autoencoders for latent space learning, Multiple Kernel Learning for feature selection, clustering.
result Lower redundancy and better clustering performance compared to benchmarks.
Data diversity is critical to success when training deep learning models. Medical imaging data sets are often imbalanced as pathologic findings are generally rare, which introduces significant challenges when training deep learning models. In this work, we propose a method to generate synthetic abnormal MRI images with…
NAS improves gliomas segmentation on MRI scans.
problem Designing optimal deep learning architectures for brain tumor segmentation.
method Neural architecture search with probabilistic parameter learning for MRI brain tumor segmentation.
result Two optimal neural architectures for brain tumor segmentation were discovered.
Deep learning models brain deformations based on atrophy and growth data.
problem Simulating brain deformations due to atrophy and growth.
method Differentiable biomechanical model using deep learning.
result Trained model can rapidly simulate new brain deformations with minimal residuals.
Study generates synthetic MR images to improve glioma segmentation.
problem Scarce annotated medical image data for glioma patients.
method Used generative adversarial networks (GANs) to create synthetic MR images.
result Synthetic images improved U-Net segmentation performance.
The efficiency of deep machine learning for automatic delineation of tumor areas has been demonstrated for intraoperative neuronavigation using active IR-mapping with the use of the cold test. The proposed approach employs a matrix IR-imager to remotely register the space-time distribution of surface temperature patter…
Challenge aims to develop automated meningioma MRI segmentation models.
problem Lack of automated, objective tools for meningioma assessment.
method Develop and evaluate models on largest annotated dataset.
result Improved care of patients with meningioma through automated segmentation.
Paper presents a machine learning method to predict cancer sub-clones.
problem Predicting the growth of sub-clones in cancer tumors.
method Data-driven machine learning approach to capture sub-clonal characteristics.
result Machine learning can predict which sub-clones are more likely to grow.
KD-Net transfers knowledge from multi-modal to mono-modal segmentation networks.
problem Limited acquisition of multiple imaging modalities in clinical settings.
method Generalized distillation framework adapted for mono-modal networks.
result The student network outperforms baseline mono-modal networks in brain tumor segmentation.
A benchmark evaluates ioUS-to-MR synthesis methods for brain tumor surgery.
problem Difficult interpretation of ioUS images for brain tumor surgery.
method Six generators trained under four inference regimes and two targets on public data.
result SynDiff-2.5D best preserved downstream segmentation (U_Dice=0.55).
Bayesian variational inference improves medical image segmentation confidence.
problem Improving interpretability and confidence in deep learning models for medical image segmentation.
method Encoder-decoder architecture based on variational inference for segmenting brain tumor images.
result The model segments brain tumors with both aleatoric and epistemic uncertainty.
SSRCA simplifies ABM sensitivity analysis using machine learning.
problem Hardness of performing sensitivity analysis for complex ABMs.
method Machine learning pipeline (Simulate, Summarize, Reduce, Cluster, Analyze) for ABMs.
result SSRCA identifies sensitive parameters and common output patterns for ABMs.
3D CNN accurately classifies infant neurodevelopmental age from MRI scans.
problem Estimating neurodevelopmental age in infants from MRI data.
method 3D Convolutional Neural Network (3D CNN) trained on MRI images of 112 infants.
result 3D CNN achieves 99% sensitivity and 98.3% specificity in age classification.
Bayesian layer improves image segmentation and out-of-distribution detection.
problem Outlier detection in image segmentation.
method Parameter-efficient hierarchical convolutional Gaussian Processes in Wasserstein-2 space.
result Uncertainty estimates improve out-of-distribution detection.
Deep learning models for semantic segmentation of images require large amounts of data. In the medical imaging domain, acquiring sufficient data is a significant challenge. Labeling medical image data requires expert knowledge. Collaboration between institutions could address this challenge, but sharing medical data to…
Background: Virtual reality simulators and machine learning have the potential to augment understanding, assessment and training of psychomotor performance in neurosurgery residents. Objective: This study outlines the first application of machine learning to distinguish "skilled" and "novice" psychomotor performance du…
Proposes BGNN for tumor heterogeneity prediction using graph neural networks.
problem Tumor classification limitations and heterogeneity assessment challenges.
method Artificial data generation, tumor heterogeneity estimation, and BGNN model development.
result BGNN achieves 89.67% accuracy in predicting tumor heterogeneity. A new method models continuous-time counterfactual outcomes using neural controlled differential equations.
problem Estimating personalized healthcare outcomes over irregularly sampled data.
method Interpreting data as samples from a continuous-time process, modeling latent trajectory using controlled differential equations, and using adversarial training for time-dependent confounding.
result TE-CDE consistently outperforms existing approaches in irregularly sampled scenarios.
Trans-Unet predicts brain folding patterns from 3D point-clouds using novel 3D-to-2D transformation.
problem Challenges in learning high-fidelity 3D point-cloud features, including permutation invariance and fine-grained surface reconstruction.
method Transform 3D point-clouds into a 2D grid domain, then use a U-shaped hybrid model with CNNs and self-attention mechanisms.
result Trans-Unet achieves high-resolution predictions of brain patch growth, surpassing existing methods in fidelity and accuracy.
Deep learning improves tumor type classification accuracy.
problem Classifying cancer types based on DNA mutations is challenging.
method Deep transfer learning and fine-tuning of gene expression data.
result Significantly improved tumor type classification accuracy (78.3%) using DNA point mutations.
A novel 3D U-Net approach improves kidney tumor segmentation in medical imaging.
problem Challenging manual annotation and great medical impact of kidney tumor segmentation.
method End-to-end cascaded U-Nets with a localization network.
result Achieves Sørensen-Dice coefficients of 0.902 for kidney and 0.408 for tumor segmentation.
Deep neural network models used for medical image segmentation are large because they are trained with high-resolution three-dimensional (3D) images. Graphics processing units (GPUs) are widely used to accelerate the trainings. However, the memory on a GPU is not large enough to train the models. A popular approach to …
This study improves lung tumor segmentation in mice MRI scans with nnU-Net, reducing annotation needs.
problem Accurate lung tumor segmentation in mice MRI scans for drug discovery.
method Optimized nnU-Net 3D model for lung tumor segmentation with minimal annotations.
result nnU-Net 3D models outperform 2D models in MRI mice scans, requiring fewer annotations.
Resting-state functional MRI (rs-fMRI) in functional neuroimaging techniques have improved in brain disorders, dysfunction studies via mapping the topology of the brain connections, i.e. connectopic mapping. Since, there are the slight differences between healthy and unhealthy brain regions and functions, investigation…