DBGDGM models dynamic brain graphs for better understanding brain function.
problem Previous brain graph models ignore temporal dynamics, limiting their usefulness.
method DBGDGM clusters brain regions into evolving communities and learns dynamic node embeddings.
result DBGDGM outperforms baselines in graph generation, dynamic link prediction, and graph classification.
Extracts causal brain dynamics across multiple scales.
problem Statistical associations do not reflect causal mechanisms in brain dynamics.
method Multiscale causal backbone (MCB) extraction using advanced causal structure learning.
result Sparse MCBs reveal distinct causal roles at different brain frequency bands.
New method for analyzing brain dynamics using HMMs and graph models.
problem Limited ability of current brain models to explain spontaneous dynamic state changes.
method Hidden Markov Graph Models (HMGMs) and spatiotemporal random walks.
result Identification of important brain community structures.
New method learns dynamic brain communication patterns across regions.
problem Current methods struggle with time-varying brain communications and scalability.
method Adaptive Delay Model (ADM) using Markovian Gaussian Processes.
result Captures dynamic neural communication patterns over time.
STCA discovers dynamic functional brain networks using spatial-temporal convolution and attention.
problem Lack of dynamic exploration of functional brain networks.
method Spatial-Temporal Convolutional Attention (STCA) model.
result STCA can discover dynamic functional brain networks in a novel way.
DynDepNet learns dynamic brain graphs from fMRI data for better prediction performance.
problem Static brain graphs from fMRI data lead to poor GNN performance.
method Dynamic Graph Structure Learning for time-varying brain connectivity.
result DynDepNet achieves state-of-the-art sex classification accuracy on real-world fMRI data.
CREIMBO models diverse brain activity by identifying hidden neural sub-circuits and their non-stationary interactions.
problem Lack of alignment in neural recordings limits analysis of brain-wide dynamics.
method CREIMBO learns a unified model of neural dynamics by assuming multiple hidden global sub-circuits representing ensemble interactions.
result CREIMBO discovers session-specific neural ensembles and their non-stationary interactions, revealing cross-subject neural mechanisms.
Unified framework detects dynamic community structure in brain networks across individuals.
problem Detecting community structure in functional brain networks across multiple subjects and over time.
method Markov-switching stochastic block model (MSS-SBM) for multilayer brain networks.
result Captures dynamic reconfiguration of modular connectivity in brain networks across different task conditions.
GNNs improve brain activity forecasting in fMRI studies.
problem Understanding neural dynamics in the brain.
method Comparison of GNN architectures for modeling fMRI data.
result GNNs outperform VAR models in robustly scaling to large network studies.
Foundational brain dynamics model using stochastic optimal control.
problem Complex and noisy fMRI signals in brain dynamics.
method Continuous-discrete state space model with amortized inference and locally linear approximations.
result State-of-the-art results across various downstream tasks.
NeuroPaint infers missing brain area dynamics from multi-animal datasets.
problem Leveraging multi-animal datasets to understand interactions between brain areas.
method Masked autoencoding approach trained across animals with partial observations.
result Models can successfully reconstruct dynamics of unrecorded brain areas.
Understanding the functional architecture of the brain in terms of networks is becoming increasingly common. In most fMRI applications functional networks are assumed to be stationary, resulting in a single network estimated for the entire time course. However recent results suggest that the connectivity between brain …
In this paper, we propose a novel unsupervised learning method to learn the brain dynamics using a deep learning architecture named residual D-net. As it is often the case in medical research, in contrast to typical deep learning tasks, the size of the resting-state functional Magnetic Resonance Image (rs-fMRI) dataset…
The goal of the present study is to identify autism using machine learning techniques and resting-state brain imaging data, leveraging the temporal variability of the functional connections (FC) as the only information. We estimated and compared the FC variability across brain regions between typical, healthy subjects …
As a mental disorder progresses, it may affect brain structure, but brain function expressed in brain dynamics is affected much earlier. Capturing the moment when brain dynamics express the disorder is crucial for early diagnosis. The traditional approach to this problem via training classifiers either proceeds from ha…
Novel method models dynamic brain graphs from time series data.
problem Generating hypotheses for dynamic brain states.
method Conditionally weighted superposition of static graphs.
result Improves f1-scores by 22-28% on average over baselines.
Transfer entropy shows abnormal brain connectivity in depression.
problem Abnormal brain connectivity in depression.
method Transfer entropy analysis on EEG recordings.
result Aberrated dynamics and direction of information between brain centers in depression.
Large bundles of myelinated axons, called white matter, anatomically connect disparate brain regions together and compose the structural core of the human connectome. We recently proposed a method of measuring the local integrity along the length of each white matter fascicle, termed the local connectome. If communicat…
Financial markets modeled like brain networks using dMNC.
problem Understanding latent dynamics in financial markets.
method Biologically inspired framework using dMNC.
result Structural persistence, regime shifts, and early warning signals identified.
Improved KAN model explains brain dynamics through edge learning and synaptic strength.
problem Explaining brain dynamics and frequencies in different brain regions.
method ELKAN (Edge Learning KNN) model with edge learning and trimming, inspired by brain science.
result ELKAN model outperforms KAN in explaining brain frequencies and dynamics.
Model captures neural activity related to behavior while separating internal computations.
problem Capturing neural activity related to behavior from complex brain recordings.
method Behavior-decomposed linear dynamical systems (b-dLDS) model.
result Improves over state-of-the-art models in disentangling behavior-related dynamics.
Framework for imputing missing heart data to simulate brain-heart interactions.
problem Lack of multi-modal patient data representing heart and brain processes.
method Probabilistic framework for joint cardiac data imputation and mechanistic model personalization.
result Accurate imputation of missing cardiac features in incomplete datasets.
Synthesizes computational approaches to understand neural timescales.
problem Varying definitions and measurements of neural timescales across studies.
method Reviews data analysis methods, biophysical models, and machine learning models.
result Complements experimental studies with a holistic view of neural timescales.
BrainCast predicts whole-brain fMRI time series from short scans.
problem Short scans reduce fMRI data quality and statistical power.
method Spatio-temporal forecasting framework for fMRI time series.
result BrainCast improves fMRI time series quality and prediction.
Many real-world data sets, especially in biology, are produced by complex nonlinear dynamical systems. In this paper, we focus on brain calcium imaging (CaI) of different organisms (zebrafish and rat), aiming to build a model of joint activation dynamics in large neuronal populations, including the whole brain of zebra…
Modeling brain dynamics to better understand and control complex behaviors underlying various cognitive brain functions are of interests to engineers, mathematicians, and physicists from the last several decades. With a motivation of developing computationally efficient models of brain dynamics to use in designing cont…
Framework integrates brain connectivity data for clinical predictions.
problem Predicting clinical outcomes from brain connectivity data.
method Structurally-regularized Dynamic Dictionary Learning (sr-DDL) and LSTM-ANN block.
result Framework outperforms state-of-the-art approaches in clinical outcome prediction.
Resting-state functional MRI (rs-fMRI) in functional neuroimaging techniques have improved in brain disorders, dysfunction studies via mapping the topology of the brain connections, i.e. connectopic mapping. Since, there are the slight differences between healthy and unhealthy brain regions and functions, investigation…
Brain-computer interfaces (BCIs) have enabled prosthetic device control by decoding motor movements from neural activities. Neural signals recorded from cortex exhibit nonstationary property due to abrupt noises and neuroplastic changes in brain activities during motor control. Current state-of-the-art neural signal de…
The paper characterizes brain states and transitions using functional MRI data.
problem Characterizing the dynamic reconfiguration of neural systems in brain states.
method Bayesian model-based characterization of latent brain states and posterior predictive discrepancy using the latent block model.
result The model detects transitions between latent brain states and identifies distinctive community patterns in task-fMRI data.
Meta-active learning optimizes control of safety-critical systems by efficiently learning dynamics and configurations.
problem Efficiently learning system dynamics and optimal configurations for safety-critical systems like deep brain stimulation.
method Meta-learning an acquisition function using LSTM, cast as meta-learning, with a mixed-integer linear program policy.
result Achieved a 46% increase in information gain and a 20% speedup in computation time over baselines.
The characterisation of the brain as a "connectome", in which the connections are represented by correlational values across timeseries and as summary measures derived from graph theory analyses, has been very popular in the last years. However, although this representation has advanced our understanding of the brain f…
Data-driven spatial filtering algorithms optimize scores such as the contrast between two conditions to extract oscillatory brain signal components. Most machine learning approaches for filter estimation, however, disregard within-trial temporal dynamics and are extremely sensitive to changes in training data and invol…
Novel approach detects early warning indicators in complex systems.
problem Detecting abrupt transitions in complex systems.
method Directed anisotropic diffusion map and latent stochastic dynamical systems.
result Early warning indicators can detect tipping points in state transitions.
Whole MILC learns brain disorder dynamics from unlabeled data.
problem Learning spatio-temporal brain disorder dynamics from unlabeled data.
method Self-supervised pre-training of whole MILC on unlabeled healthy control data.
result Whole MILC outperforms existing methods and provides diagnostic insights.
A powerful approach for understanding neural population dynamics is to extract low-dimensional trajectories from population recordings using dimensionality reduction methods. Current approaches for dimensionality reduction on neural data are limited to single population recordings, and can not identify dynamics embedde…
Autoencoders identify brain networks linked to stress and genotype.
problem Designing effective brain stimulation protocols for mental illnesses.
method Supervised autoencoders to model multi-region brain activity.
result Autoencoders reveal a stress-related brain network associated with a bipolar disorder genotype.
Novel framework predicts brain biomarker trajectories with superior performance.
problem Challenges in estimating longitudinal brain biomarker trajectories due to variability, inconsistencies, and irregular measurements.
method Personalized deep kernel regression with Adaptive Shrinkage Estimation.
result Superior predictive performance compared to state-of-the-art models.
ST-GCN improves rs-fMRI prediction accuracy by modeling spatio-temporal graph connectivity.
problem Existing rs-fMRI methods neglect functional connectivity or temporal dynamics.
method Spatio-temporal graph convolutional network (ST-GCN) trained on BOLD time series.
result ST-GCN predicts gender and age more accurately than common methods.
Derives continuum model from discrete ε-graphs with connectivity functional.
problem Modeling diffusion in networks with varying connectivity.
method Energy-based continuum limit derivation, neural-network reconstruction of connectivity.
result Error between discrete and continuum energies is O(ε), valid even with fluctuations. A wearable EEG headband detects primary colors from brain activity for color perception.
problem Detecting primary colors from brain activity for color perception.
method Spectral power features, statistical features, and correlation features from continuous Morlet wavelet transform; dimensionality reduction techniques like Forward Feature Selection and Stacked Autoencoders; Random Forest Classifier.
result Best overall accuracy of 80.6% for intra-subject classification.
Enhances disease progression modeling using LLMs for complex brain connectivity.
problem Inaccurate predictions of disease spread due to oversimplified brain connectivity models.
method Uses LLMs to synthesize multi-modal relationships and learn disease trajectories from longitudinal data.
result Superior prediction accuracy and interpretability compared to traditional methods.
Study adapts β-TCVAE for fMRI to recover nonlinear brain components.
problem Capturing nonlinear brain dynamics in fMRI data.
method Adapted β-TCVAE framework for fMRI data. result Recovery of meaningful nonlinear spatial components in fMRI data.
Novel method uses information theory to measure causal influences during transient neural events.
problem Characterizing network interactions during transient neural events.
method Structural Causal Models, Information Theory, Transfer Entropy, Dynamic Causal Strength, Relative Dynamic Causal Strength.
result Introduced a novel measure, relative Dynamic Causal Strength, with theoretical and empirical support.
Understanding the dynamics of brain tumor progression is essential for optimal treatment planning. Cast in a mathematical formulation, it is typically viewed as evaluation of a system of partial differential equations, wherein the physiological processes that govern the growth of the tumor are considered. To personaliz…
Novel approach constructs differential causal networks from EEG data.
problem Difficulty in modeling interactions of thousands of neurons in group comparisons.
method Hierarchical differential dynamic causal nets based on Chen-Fliess expansions.
result Evidence of network functional disruptions in epileptic brains.
Current high-throughput data acquisition technologies probe dynamical systems with different imaging modalities, generating massive data sets at different spatial and temporal resolutions posing challenging problems in multimodal data fusion. A case in point is the attempt to parse out the brain structures and networks…
New algorithm learns switching dynamics from multiple neural signals.
problem Learning accurate switching dynamical system models from multimodal neural data.
method Unsupervised learning algorithm for multiscale switching dynamical system models.
result Switching multiscale dynamical system models outperform single-scale models in behavior decoding.