Machine learning improves diagnostic test accuracy for bovine tuberculosis.
problem Improving diagnostic test sensitivity for bovine tuberculosis.
method Machine learning to assess risk landscapes and predict infection.
result Test sensitivity improved, detecting 240 more infected herds per year.
Machine learning has been an emerging tool for various aspects of infectious diseases including tuberculosis surveillance and detection. However, WHO provided no recommendations on using computer-aided tuberculosis detection software because of the small number of studies, methodological limitations, and limited genera…
Proposes TPIS for early and low-cost TB vs. pneumonia diagnosis.
problem Challenges in differentiating TB from pneumonia.
method Two-step decision support system with stacked ensemble classifiers.
result TPIS outperforms other methods in early and final diagnosis.
The study uses neural networks to classify and predict coronavirus data.
problem Classifying and predicting coronavirus data from input variables.
method Artificial neural networks with logcosh loss function to classify branches of set-valued mappings.
result Successfully classified and predicted coronavirus data for each German district.
Personalized models explain TB treatment outcomes considering patient context.
problem Heterogeneity in TB treatment outcomes due to co-morbidities.
method Multi-task learning approach encoding patient context into personalized models.
result Identifies anemia, age of onset, and HIV as influential for treatment efficacy.
Digital Adherence Technologies (DATs) are an increasingly popular method for verifying patient adherence to many medications. We analyze data from one city served by 99DOTS, a phone-call-based DAT deployed for Tuberculosis (TB) treatment in India where nearly 3 million people are afflicted with the disease each year. T…
EGDL predicts TB outbreaks with deep learning, integrating epidemiological models.
problem Predicting TB outbreaks with complex spatiotemporal dynamics.
method Modified MN-SIR model with Bayesian inference, deep neural networks.
result EGDL delivers robust and accurate TB outbreak predictions.
Designing a new drug is a lengthy and expensive process. As the space of potential molecules is very large (10^23-10^60), a common technique during drug discovery is to start from a molecule which already has some of the desired properties. An interdisciplinary team of scientists generates hypothesis about the required…
A standard technique for understanding underlying dependency structures among a set of variables posits a shared conditional probability distribution for the variables measured on individuals within a group. This approach is often referred to as module networks, where individuals are represented by nodes in a network, …
The paper investigates deep neural networks for medical imaging applications, providing interpretable results.
problem Uninterpretable decisions made by deep neural networks in medical imaging applications.
method Investigation of deep neural networks for malaria, diabetic retinopathy, brain tumor, and tuberculosis detection in various imaging modalities. Visualization of class activation mappings provided.
result Visualization of class activation mappings enhances understanding of deep neural networks and aids doctors in decision-making.
Proposes a method to quantify uncertainty in DNN models for discrete inputs.
problem Uncertainty quantification for DNN models with categorical and discrete feature variables.
method Develops a mathematical framework to quantify prediction uncertainty from discrete input noise and model parameters.
result Identifies risk-sensitive cases prone to misclassification due to discrete predictor errors.
New bandit model for healthcare intervention planning.
problem Maximizing patient health with limited monitoring resources.
method Developed Collapsing Bandits model and derived optimal policies.
result 3-order-of-magnitude speedup in algorithm performance.
Double descent observed in tree-based models for genomic prediction.
problem Understanding the generalization behavior of tree-based models in machine learning.
method Systematic variation of model complexity in a genomic prediction task using whole-genome sequencing data.
result Double descent emerges only when complexity is scaled jointly across learner capacity and ensemble size.