Modeling bone microarchitecture adaptation using geometric flows.
arXiv research
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Deep-learning method estimates bone 3D structure from X-ray images.
Characterizes graphs with Lin-Lu-Yau curvature at least one and explores bone-idle graphs.
Six AI solutions accurately detect growth plate planes in mice bone scans.
Insufficient training data and severe class imbalance are often limiting factors when developing machine learning models for the classification of rare diseases. In this work, we address the problem of classifying bone lesions from X-ray images by increasing the small number of positive samples in the training set. We …
Suppressing bones on chest X-rays such as ribs and clavicle is often expected to improve pathologies classification. These bones can interfere with a broad range of diagnostic tasks on pulmonary disease except for musculoskeletal system. Current conventional method for acquisition of bone suppressed X-rays is dual ener…
Purpose: We perform anatomical landmarking for craniomaxillofacial (CMF) bones without explicitly segmenting them. Towards this, we propose a new simple yet efficient deep network architecture, called \textit{relational reasoning network (RRN)}, to accurately learn the local and the global relations among the landmarks…
Curvature formulas on regular graphs identified bone idle edges and graphs.
A new algorithm discovers causal factors between T2DM and bone mineral density.
In microsurgery, lasers have emerged as precise tools for bone ablation. A challenge is automatic control of laser bone ablation with 4D optical coherence tomography (OCT). OCT as high resolution imaging modality provides volumetric images of tissue and foresees information of bone position and orientation (pose) as we…
Bayesian CNN estimates uncertainty in bone age prediction.
The automatic segmentation of human knee cartilage from 3D MR images is a useful yet challenging task due to the thin sheet structure of the cartilage with diffuse boundaries and inhomogeneous intensities. In this paper, we present an iterative multi-class learning method to segment the femoral, tibial and patellar car…
Predicting the number of clock cycles a processor takes to execute a block of assembly instructions in steady state (the throughput) is important for both compiler designers and performance engineers. Building an analytical model to do so is especially complicated in modern x86-64 Complex Instruction Set Computer (CISC…
Concept bottleneck models enable concept manipulation for model interpretation.
Magnetic resonance imaging (MRI) has been proposed as a complimentary method to measure bone quality and assess fracture risk. However, manual segmentation of MR images of bone is time-consuming, limiting the use of MRI measurements in the clinical practice. The purpose of this paper is to present an automatic proximal…
Unified framework for Bayesian online learning in changing conditions.
X-rays are commonly performed imaging tests that use small amounts of radiation to produce pictures of the organs, tissues, and bones of the body. X-rays of the chest are used to detect abnormalities or diseases of the airways, blood vessels, bones, heart, and lungs. In this work we present a stochastic attention-based…
The premorbid geometry of the mandible is of significant relevance in jaw reconstructive surgeries and occasionally unknown to the surgical team. In this paper, an optimization framework is introduced to train deep models for completion (reconstruction) of the missing segments of the bone based on the remaining healthy…
With the help of transfer entropy, we analyze information flows between communities of complex networks. We show that the transfer entropy provides a coherent description of interactions between communities, including non-linear interactions. To put some flesh on the bare bones, we analyze transfer entropies between co…
We build CSI-Net, a unified Deep Neural Network~(DNN), to learn the representation of WiFi signals. Using CSI-Net, we jointly solved two body characterization problems: biometrics estimation (including body fat, muscle, water, and bone rates) and person recognition. We also demonstrated the application of CSI-Net on tw…
Multifractal analysis is one of the important approaches that enables us to measure the complexity of various data via the scaling properties. We compare the most common techniques used for multifractal exponents estimation from both theoretical and practical point of view. Particularly, we discuss the methods based on…
Automatic segmentation of auditory ossicles from CT images using Ricci curvature.
DVNet efficiently segments large neurovascular datasets using skip connections.
Outcome regressed on class labels identified by unsupervised clustering is custom in many applications. However, it is common to ignore the misclassification of class labels caused by the learning algorithm, which potentially leads to serious bias of the estimated effect parameters. Due to its generality we suggest to …
Efficient deep learning model classifies fractures from X-rays.
We show how to compute the circular area invariant of planar curves, and the spherical volume invariant of surfaces, in terms of line and surface integrals, respectively. We use the Divergence Theorem to express the area and volume integrals as line and surface integrals, respectively, against particular kernels; our r…
The paper explores three methods to assign a metric to shape spaces.
Superstatistics is a widely employed tool of non-equilibrium statistical physics which plays an important role in analysis of hierarchical complex dynamical systems. Yet, its "canonical" formulation in terms of a single nuisance parameter is often too restrictive when applied to complex empirical data. Here we show tha…
We propose approaches based on deep learning to localize objects in images when only a small training dataset is available and the images have low quality. That applies to many problems in medical image processing, and in particular to the analysis of fluoroscopic (low-dose) X-ray images, where the images have low cont…
AECF improves multimodal inference robustness and calibration.
ChronoMID builds on the success of cross-modal convolutional neural networks (X-CNNs), making the novel application of the technique to medical imaging data. Specifically, this paper presents and compares alternative approaches - timestamps and difference images - to incorporate temporal information for the classificat…
Celiac Disease (CD) is a chronic autoimmune disease that affects the small intestine in genetically predisposed children and adults. Gluten exposure triggers an inflammatory cascade which leads to compromised intestinal barrier function. If this enteropathy is unrecognized, this can lead to anemia, decreased bone densi…
Genome-wide association studies (GWAS) have emerged as a rich source of genetic clues into disease biology, and they have revealed strong genetic correlations among many diseases and traits. Some of these genetic correlations may reflect causal relationships. We developed a method to quantify causal relationships betwe…
This paper presents the first deep reinforcement learning (DRL) framework to estimate the optimal Dynamic Treatment Regimes from observational medical data. This framework is more flexible and adaptive for high dimensional action and state spaces than existing reinforcement learning methods to model real-life complexit…
Improves matrix multiplication throughput for asymmetric bit-width operands.
Develops a neural surrogate for proton dose calculation using Monte Carlo dropout uncertainty.
We construct genomic predictors for heritable and extremely complex human quantitative traits (height, heel bone density, and educational attainment) using modern methods in high dimensional statistics (i.e., machine learning). Replication tests show that these predictors capture, respectively, 40, 20, and 9 perc…
This paper tackles the challenge presented by small-data to the task of Bayesian inference. A novel methodology, based on manifold learning and manifold sampling, is proposed for solving this computational statistics problem under the following assumptions: 1) neither the prior model nor the likelihood function are Gau…
Study geodesic X-ray transform and streaking artifacts on simple surfaces or spaces of constant curvature.
New method classifies reticulocytes from red blood cells without labels.
In clinical practice and biomedical research, measurements are often collected sparsely and irregularly in time while the data acquisition is expensive and inconvenient. Examples include measurements of spine bone mineral density, cancer growth through mammography or biopsy, a progression of defective vision, or assess…
The paper estimates Betti numbers for graphs with specific curvatures, proving bounds and characterizing rigidity.
Paper uses optimal transport for low-dimensional representation of leukemia flow cytometry data.
Neural network solves inverse problem in multiscale mechanics.
The paper proves properties of minimal isometric embeddings and conformal deformations of Riemannian surfaces.