Enhancement attacks can falsely improve machine learning model performance in biomedical research.
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Review of modern computational optimal transport methods for biomedical applications.
Model predicts future term connections in biomedical research.
Machine learning speeds up FLIM analysis in biomedical research.
Study improves LLMs for PPI analysis by addressing uncertainty.
In medicine, visualizing chromosomes is important for medical diagnostics, drug development, and biomedical research. Unfortunately, chromosomes often overlap and it is necessary to identify and distinguish between the overlapping chromosomes. A segmentation solution that is fast and automated will enable scaling of co…
Deep learning methods have shown extraordinary potential for analyzing very diverse biomedical data, but their dissemination beyond developers is hindered by important computational hurdles. We introduce ImJoy (https://imjoy.io/), a flexible and open-source browser-based platform designed to facilitate widespread reuse…
Proposes a novel method to identify complex effects in multi-view datasets.
Proposes a framework for causal inference with processed outcomes in biomedical research.
Biomedical research papers use significantly different language and jargon when compared to typical English text, which reduces the utility of pre-trained NLP models in this domain. Meanwhile Medline, a database of biomedical abstracts, introduces nearly a million new documents per-year. Applications that could benefit…
A rigorous ML pipeline for binary classification in biomedical studies, focusing on pancreatic cancer.
Biomedical documents such as Electronic Health Records (EHRs) contain a large amount of information in an unstructured format. The data in EHRs is a hugely valuable resource documenting clinical narratives and decisions, but whilst the text can be easily understood by human doctors it is challenging to use in research …
Automated digital twin discovery from biological data improves drug discovery and personalized medicine.
Using different sources of information to support automated extracting of relations between biomedical concepts contributes to the development of our understanding of biological systems. The primary comprehensive source of these relations is biomedical literature. Several relation extraction approaches have been propos…
This manuscript addresses the problem of the automatic lesion boundary detection in dermoscopy, using deep neural networks. An approach is based on the adaptation of the U-net convolutional neural network with skip connections for lesion boundary segmentation task. I hope this paper could serve, to some extent, as an e…
Quantum neural networks improve causal inference in biomedical studies, especially for small samples.
Discovering associations is of central importance in scientific practices. Currently, most researches consider only linear association measured by correlation coefficient, which has its theoretical limitations. In this paper, we propose a new method for discovering association with copula entropy -- a universal applica…
Locally sparse neural networks improve interpretability for biomedical tabular data.
BIOMRC dataset improves MRC performance, especially for non-experts.
ROOFS helps researchers select robust biomarker features from complex data.
Method integrates logical rules into neural multi-hop reasoning for drug repurposing.
Paper proposes a new method for imputing missing biomedical data.
Information about the contributions of individual authors to scientific publications is important for assessing authors' achievements. Some biomedical publications have a short section that describes authors' roles and contributions. It is usually written in natural language and hence author contributions cannot be tri…
Medical research is risky and expensive. Drug discovery, as an example, requires that researchers efficiently winnow thousands of potential targets to a small candidate set for more thorough evaluation. However, research groups spend significant time and money to perform the experiments necessary to determine this cand…
In biomedical research, many different types of patient data can be collected, such as various types of omics data and medical imaging modalities. Applying multi-view learning to these different sources of information can increase the accuracy of medical classification models compared with single-view procedures. Howev…
Entity linking is the task of linking mentions of named entities in natural language text, to entities in a curated knowledge-base. This is of significant importance in the biomedical domain, where it could be used to semantically annotate a large volume of clinical records and biomedical literature, to standardized co…
SMM improves signal recovery from noisy data.
SigTime learns interpretable signatures from time series data.
The support vector machine (SVM) is a widely used machine learning tool for classification based on statistical learning theory. Given a set of training data, the SVM finds a hyperplane that separates two different classes of data points by the largest distance. While the standard form of SVM uses L2-norm regularizatio…
Paper proposes a new method for estimating treatment effects using interpretable deep learning models.
Electronic health records (EHRs) have contributed to the computerization of patient records and can thus be used not only for efficient and systematic medical services, but also for research on biomedical data science. However, there are many missing values in EHRs when provided in matrix form, which is an important is…
Monitoring the biomedical literature for cases of Adverse Drug Reactions (ADRs) is a critically important and time consuming task in pharmacovigilance. The development of computer assisted approaches to aid this process in different forms has been the subject of many recent works. One particular area that has shown pro…
The paper advocates for interpretable, accountable, reproducible machine learning in medicine.
Method cleans noisy training labels for biomedical data.
HOoD detects near-out-of-distribution groups in correlated biomedical assays.
Deep learning has shown its great promise in various biomedical image segmentation tasks. Existing models are typically based on U-Net and rely on an encoder-decoder architecture with stacked local operators to aggregate long-range information gradually. However, only using the local operators limits the efficiency and…
New DL model handles missing data in biomedical datasets.
Biomedical data are widely accepted in developing prediction models for identifying a specific tumor, drug discovery and classification of human cancers. However, previous studies usually focused on different classifiers, and overlook the class imbalance problem in real-world biomedical datasets. There are a lack of st…
Measurement noise limits the advantage of nonlinear models over linear models in biomedical prediction
spex-LVM infers interpretable latent factors from biomedical data.
Much recent research aims to identify evidence for Drug-Drug Interactions (DDI) and Adverse Drug reactions (ADR) from the biomedical scientific literature. In addition to this "Bibliome", the universe of social media provides a very promising source of large-scale data that can help identify DDI and ADR in ways that ha…
Biomedical text tagging systems are plagued by the dearth of labeled training data. There have been recent attempts at using pre-trained encoders to deal with this issue. Pre-trained encoder provides representation of the input text which is then fed to task-specific layers for classification. The entire network is fin…
We report a neural architecture search framework, BioNAS, that is tailored for biomedical researchers to easily build, evaluate, and uncover novel knowledge from interpretable deep learning models. The introduction of knowledge dissimilarity functions in BioNAS enables the joint optimization of predictive power and bio…
Many machine learning models can be attacked with adversarial examples, i.e. inputs close to correctly classified examples that are classified incorrectly. However, most research on adversarial attacks to date is limited to vectorial data, in particular image data. In this contribution, we extend the field by introduci…
Motivation: State-of-the-art biomedical named entity recognition (BioNER) systems often require handcrafted features specific to each entity type, such as genes, chemicals and diseases. Although recent studies explored using neural network models for BioNER to free experts from manual feature engineering, the performan…
Classification of seizure type is a key step in the clinical process for evaluating an individual who presents with seizures. It determines the course of clinical diagnosis and treatment, and its impact stretches beyond the clinical domain to epilepsy research and the development of novel therapies. Automated identific…
CARVE validates clustering results using resampling and stability analysis.
VICatMix clusters categorical biomedical data efficiently and selects relevant variables.