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168,742 papers · 148 categories

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48 results for biomedical domains

A multi-task learning model for slot tagging in biomedical domains.

problem Limited labeled data, memory constraints, and domain-specific slot types.
method Multi-task learning using deep bidirectional transformers.
result Outperforms previous state-of-the-art systems in efficiency and effectiveness.

New algorithm improves model generalization in structured biomedical domains.

problem Improving model generalization in structured biomedical domains.
method Proposes a new regret minimization (RGM) algorithm and its structured extension for better performance in diverse environments.
result Significantly outperforms previous state-of-the-art baselines on molecular property prediction, protein homology, and stability prediction.

Generates biomedical abstracts from titles, years, and keywords.

problem Difficulties in understanding biomedical research papers due to specialized language.
method Conditional transformer-based language model with metadata conditioning.
result Generated abstracts are more relevant and non-trivial than GPT-2.

Locally sparse neural networks improve interpretability for biomedical tabular data.

problem Overfitting and lack of interpretability in neural networks for tabular biomedical data.
method Locally sparse neural network with a gating network to select relevant features.
result The method outperforms state-of-the-art models in synthetic and real-world biomedical datasets.

SiMLR reduces complex biomedical data into simpler, interpretable forms.

problem Handling high-dimensional biomedical data for better understanding and prediction.
method Similarity-driven multi-view linear reconstruction (SiMLR) with novel objective function and regularization.
result SiMLR outperforms other methods in various biomedical datasets.

Capturing sentence semantics plays a vital role in a range of text mining applications. Despite continuous efforts on the development of related datasets and models in the general domain, both datasets and models are limited in biomedical and clinical domains. The BioCreative/OHNLP organizers have made the first attemp…

2019-09-06abs ↗pdf ↗

Eliciting semantic similarity between concepts in the biomedical domain remains a challenging task. Recent approaches founded on embedding vectors have gained in popularity as they risen to efficiently capture semantic relationships The underlying idea is that two words that have close meaning gather similar contexts. …

2018-11-28abs ↗pdf ↗

LLM-Lasso uses LLMs to improve feature selection in Lasso regression.

problem Improving feature selection in Lasso regression with domain-specific knowledge.
method Combines LLMs with Lasso regularization to generate feature weights.
result Outperforms standard Lasso and feature selection baselines in biomedical studies.

ALPODS AI diagnoses high-dimensional biomedical data with human-understandable explanations.

problem AI decisions in high-dimensional biomedical data are not explainable to humans.
method ALPODS method classifies data based on clusters and generates fuzzy reasoning rules.
result ALPODS provides understandable explanations for AI diagnoses.

AGATHA predicts promising research directions from scientific data.

problem Efficiently winnowing thousands of potential targets in drug discovery.
method Deep-learning hypothesis generation system that ranks plausible term-pairs.
result Best-in-class performance on an established benchmark, high recommendation scores across subdomains.

This work abstracts deep neural networks into concept graphs for better interpretability in medical tasks.

problem Lack of interpretability in deep learning models, especially in medical domains.
method Developed a graphical representation of medical image processing models to understand concept-based reasoning.
result Extracted a concept-level graph that reveals the decision-making process of deep learning models.

Smile-GANs clusters brain MRI scans to reveal disease subtypes and progression.

problem Understanding disease heterogeneity in brain MRI scans.
method Generative Adversarial Networks (GANs) for semi-supervised clustering.
result Discovered four subtypes of Alzheimer's and prodromal phases, with two progressive pathways.

Model predicts future term connections in biomedical research.

problem Capturing temporal dynamics and unobserved connections in biomedical term relationships.
method Variational inference model for positive-unlabeled learning on dynamic graphs.
result Model effectively predicts term relationships in real-world datasets.

Enhancement attacks can falsely improve machine learning model performance in biomedical research.

problem The trustworthiness of machine learning in biomedical research is threatened by enhancement attacks.
method Developed two techniques to enhance prediction performance with minimal changes to features.
result Falsely improved classifiers' accuracy from 50% to almost 100% while maintaining high feature similarities.

Review of modern computational optimal transport methods for biomedical applications.

problem Efficient computation of optimal transport for big data.
method Regularization-based and projection-based computational methods.
result Advancements in computational optimal transport methods for biomedical research.

Non-negative blind source separation (non-negative BSS), which is also referred to as non-negative matrix factorization (NMF), is a very active field in domains as different as astrophysics, audio processing or biomedical signal processing. In this context, the efficient retrieval of the sources requires the use of sig…

2014-07-29abs ↗pdf ↗

Method integrates logical rules into neural multi-hop reasoning for drug repurposing.

problem Capturing long-range dependencies in biomedical data.
method Combines logical rules with neural multi-hop reasoning using reinforcement learning.
result Our method outperforms baseline methods in drug repurposing tasks.

GOPSA optimizes EEG data for cross-site age prediction, improving performance on multiple metrics.

problem Predictive shifts in EEG data from different sites and participants.
method Geodesic Optimization for Predictive Shift Adaptation (GOPSA) on the SPD manifold.
result Significantly higher performance on age prediction metrics compared to state-of-the-art methods.

Generative model learns shape drift for quantifying domain uncertainty in hemodynamics.

problem Quantifying domain uncertainty in medical image segmentation for biomarker estimation.
method Conditional stochastic interpolant framework based on LDDMM registration.
result Generative model can create random perturbations of shapes for biomarker estimation.

Machine Learning (ML) helps us to recognize patterns from raw data. ML is used in numerous domains i.e. biomedical, agricultural, food technology, etc. Despite recent technological advancements, there is still room for substantial improvement in prediction. Current ML models are based on classical theories of probabili…

2019-03-04abs ↗pdf ↗

SigTime learns interpretable signatures from time series data.

problem Discovering meaningful patterns in time series data with high complexity and limited interpretability.
method Jointly trains two Transformer models using shapelet-based and feature engineering representations.
result Learned shapelets serve as interpretable signatures for time series classification.

Study improves LLMs for PPI analysis by addressing uncertainty.

problem Uncertainty in LLM predictions for PPIs.
method Fine-tuned LLaMA-3 and BioMedGPT models, LoRA ensembles, Bayesian LoRA for UQ.
result Competitive PPI identification performance across diverse disease contexts.

Drug-Drug Interactions (DDIs) Extraction refers to the efforts to generate hand-made or automatic tools to extract embedded information from text and literature in the biomedical domain. Because of restrictions in hand-made efforts and their lower speed, Machine-Learning, or Deep-Learning approaches have become more po…

2019-07-31abs ↗pdf ↗

Method cleans noisy training labels for biomedical data.

problem Accurately labeling biomedical data is challenging.
method Reliability-based training data cleaning with inductive conformal prediction.
result Significant enhancements in classification performance across multiple tasks.

HOoD detects near-out-of-distribution groups in correlated biomedical assays.

problem Detecting near-out-of-distribution cases in biased or incomplete data.
method Projects correlated measurements through a trained model and uses permutation-based hypothesis tests.
result HOoD reliably identifies OoD groups, outperforming other detectors.

Deep learning has shown its great promise in various biomedical image segmentation tasks. Existing models are typically based on U-Net and rely on an encoder-decoder architecture with stacked local operators to aggregate long-range information gradually. However, only using the local operators limits the efficiency and…

2018-12-10abs ↗pdf ↗

The paper advocates for interpretable, accountable, reproducible machine learning in medicine.

problem Black box models in medicine lack transparency and regulatory approval.
method Intrinsically interpretable modeling approaches and collaborative learning paradigms.
result Interpretable machine learning models can support clinical decisions and gain regulatory approval.

Proposes a novel method to identify complex effects in multi-view datasets.

problem Challenges in analyzing multi-view biomedical datasets with complex interactions.
method Generalized kernel machine approach considering marginal and joint effects of features from different views.
result Effective identification of higher-order composite effects in multi-view datasets.

Mining relationships between treatment(s) and medical problem(s) is vital in the biomedical domain. This helps in various applications, such as decision support system, safety surveillance, and new treatment discovery. We propose a deep learning approach that utilizes both word level and sentence-level representations …

2018-06-26abs ↗pdf ↗

Two case studies reveal hidden biases and confounders in machine learning models of biomedical data.

problem Hidden biases and confounders in machine learning models of biomedical data.
method Two case studies examining biases and confounders in machine learning models of biomedical data.
result Prediction models performed well but hidden biases and confounders were revealed.

Deep learning methods have shown extraordinary potential for analyzing very diverse biomedical data, but their dissemination beyond developers is hindered by important computational hurdles. We introduce ImJoy (https://imjoy.io/), a flexible and open-source browser-based platform designed to facilitate widespread reuse…

2019-05-30abs ↗pdf ↗