Study examines how body segments respond to random vibrations.
arXiv research
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Machine learning improves concussion diagnosis in female athletes.
Background. Real-world data show that approximately 50% of psoriasis patients treated with a biologic agent will discontinue the drug because of loss of efficacy. History of previous therapy with another biologic, female sex and obesity were identified as predictors of drug discontinuations, but their individual predic…
Accurate diagnosis is crucial for preventing the progression of Parkinson's, as well as improving the quality of life with individuals with Parkinson's disease. In this paper, we develop a sex-specific and age-dependent classification method to diagnose the Parkinson's disease using the online handwriting recorded from…
We present two related methods for deriving connectivity-based brain atlases from individual connectomes. The proposed methods exploit a previously proposed dense connectivity representation, termed continuous connectivity, by first performing graph-based hierarchical clustering of individual brains, and subsequently a…
Data obtained from Flow Cytometry present pronounced variability due to biological and technical reasons. Biological variability is a well-known phenomenon produced by measurements on different individuals, with different characteristics such as illness, age, sex, etc. The use of different settings for measurement, the…
MRI image quality affects statistical and predictive analysis of brain morphology.
Sex trafficking is a global epidemic. Escort websites are a primary vehicle for selling the services of such trafficking victims and thus a major driver of trafficker revenue. Many law enforcement agencies do not have the resources to manually identify leads from the millions of escort ads posted across dozens of publi…
Greenhouse environment is the key to influence crops production. However, it is difficult for classical control methods to give precise environment setpoints, such as temperature, humidity, light intensity and carbon dioxide concentration for greenhouse because it is uncertain nonlinear system. Therefore, an intelligen…
This article applies a long short-term memory recurrent neural network to mortality rate forecasting. The model can be trained jointly on the mortality rate history of different countries, ages, and sexes. The RNN-based method seems to outperform the popular Lee-Carter model.
Two new models forecast multiple subpopulations' mortality, outperforming existing methods.
Fair and unbiased machine learning is an important and active field of research, as decision processes are increasingly driven by models that learn from data. Unfortunately, any biases present in the data may be learned by the model, thereby inappropriately transferring that bias into the decision making process. We id…
DynDepNet learns dynamic brain graphs from fMRI data for better prediction performance.
Study removes bias from chest X-ray embeddings using orthogonalization.
Graph neural networks (GNN) rely on graph operations that include neural network training for various graph related tasks. Recently, several attempts have been made to apply the GNNs to functional magnetic resonance image (fMRI) data. Despite recent progresses, a common limitation is its difficulty to explain the class…
Model predicts cannabis use disorder risk for adolescents and young adults.
Optimal algorithm selects biological models without prior info.
Researchers develop flexible kernels for biological sequences with guaranteed reliability.
A new CVaR test reduces group performance disparity detection complexity.
Machine learning algorithms can unintentionally discriminate; tools detect and fix this.
Bias in training data affects diagnostic algorithms' performance.
New learning algorithm mimics biological neural networks.
SENA-discrepancy-VAE interprets latent causal factors in biological pathways.
Biological networks are a very convenient modelling and visualisation tool to discover knowledge from modern high-throughput genomics and postgenomics data sets. Indeed, biological entities are not isolated, but are components of complex multi-level systems. We go one step further and advocate for the consideration of …
Scalable GPLVM reduces complexity in scRNA-seq data, accounting for technical and biological confounders.
DeepSIBA predicts biological effects of chemical structures using graph neural networks.
New methods improve uncertainty quantification in dynamic biological systems.
Proposes a novel network-based neighborhood regression for biological systems.
AR algorithm simplifies backpropagation with improved scalability and biological plausibility.
We solve a lifecycle model in which the consumer's chronological age does not move in lockstep with calendar time. Instead, biological age increases at a stochastic non-linear rate in time like a broken clock that might occasionally move backwards. In other words, biological age could actually decline. Our paper is ins…
Algorithm optimizes biological sequences using bootstrapped training with a score-conditioned generator.
Backpropagation is the workhorse of deep learning, however, several other biologically-motivated learning rules have been introduced, such as random feedback alignment and difference target propagation. None of these methods have produced a competitive performance against backpropagation. In this paper, we show that bi…
Fault-tolerant neural networks inspired by biological error correction codes.
Probabilistic graphical models (PGMs) have become a popular tool for computational analysis of biological data in a variety of domains. But, what exactly are they and how do they work? How can we use PGMs to discover patterns that are biologically relevant? And to what extent can PGMs help us formulate new hypotheses t…
Recent technological advancements in data acquisition tools allowed life scientists to acquire multimodal data from different biological application domains. Broadly categorized in three types (i.e., sequences, images, and signals), these data are huge in amount and complex in nature. Mining such an enormous amount of …
New risk control method for non-monotonic losses in complex parameters.
New learning rules for wide neural networks without backpropagation.
We present an analysis of the problem of identifying biological context and associating it with biochemical events in biomedical texts. This constitutes a non-trivial, inter-sentential relation extraction task. We focus on biological context as descriptions of the species, tissue type and cell type that are associated …
We introduce bio-inspired artificial neural networks consisting of neurons that are additionally characterized by spatial positions. To simulate properties of biological systems we add the costs penalizing long connections and the proximity of neurons in a two-dimensional space. Our experiments show that in the case wh…
Oja's rule improves neural network training without engineered tricks.
Graph auto-encoder predicts unobserved node features from biological networks and omics data.
Was it fair that Harry was hired but not Barry? Was it fair that Pam was fired instead of Sam? How can one ensure fairness when an intelligent algorithm takes these decisions instead of a human? How can one ensure that the decisions were taken based on merit and not on protected attributes like race or sex? These are t…
Quantitatively predicting phenotype variables by the expression changes in a set of candidate genes is of great interest in molecular biology but it is also a challenging task for several reasons. First, the collected biological observations might be heterogeneous and correspond to different biological mechanisms. Seco…
In this work, we perform an exploratory study on synthesizing deep neural networks using biological synaptic strength distributions, and the potential influence of different distributions on modelling performance particularly for the scenario associated with small data sets. Surprisingly, a CNN with convolutional layer…
Biological neural network mimics CCA for multi-channel data.
High-dimensional data acquired from biological experiments such as next generation sequencing are subject to a number of confounding effects. These effects include both technical effects, such as variation across batches from instrument noise or sample processing, or institution-specific differences in sample acquisiti…
ODBAE detects complex phenotypes in biological data.
BioBO optimizes gene perturbation design using Bayesian optimization with biological priors.