Neural network model improves leaf spectral reflectance prediction for grapevines.
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Geometric modeling for human food and chemical sensitivities.
Bayesian inference for biochemical reaction networks using jump-diffusion approximations.
Genome-wide association studies (GWAS) have emerged as a rich source of genetic clues into disease biology, and they have revealed strong genetic correlations among many diseases and traits. Some of these genetic correlations may reflect causal relationships. We developed a method to quantify causal relationships betwe…
Many complex disease syndromes such as asthma consist of a large number of highly related, rather than independent, clinical phenotypes, raising a new technical challenge in identifying genetic variations associated simultaneously with correlated traits. In this study, we propose a new statistical framework called grap…
We present an analysis of the problem of identifying biological context and associating it with biochemical events in biomedical texts. This constitutes a non-trivial, inter-sentential relation extraction task. We focus on biological context as descriptions of the species, tissue type and cell type that are associated …
Study reveals LLM personality patterns but lacks behavioral consistency.
Many methods have been used to recognize author personality traits from text, typically combining linguistic feature engineering with shallow learning models, e.g. linear regression or Support Vector Machines. This work uses deep-learning-based models and atomic features of text, the characters, to build hierarchical, …
We propose the time-dependent generalization of an `ordinary' autonomous human biomechanics, in which total mechanical + biochemical energy is not conserved. We introduce a general framework for time-dependent biomechanics in terms of jet manifolds derived from the extended musculo-skeletal configuration manifold. The …
Heterosis is the improved or increased function of any biological quality in a hybrid offspring. We have studied yet the largest maize SNP dataset for traits prediction. We develop linear and non-linear models which consider relationships between different hybrids as well as other effect. Specially designed model prove…
Ecologists have long suspected that species are more likely to interact if their traits match in a particular way. For example, a pollination interaction may be more likely if the proportions of a bee's tongue fit a plant's flower shape. Empirical estimates of the importance of trait-matching for determining species in…
Genome-wide association studies have proven to be essential for understanding the genetic basis of disease. However, many complex traits---personality traits, facial features, disease subtyping---are inherently high-dimensional, impeding simple approaches to association mapping. We developed a nonparametric Bayesian re…
Advances of modern sensing and sequencing technologies generate a deluge of high dimensional space-temporal physiological and next-generation sequencing (NGS) data. Physiological traits are observed either as continuous random functions, or on a dense grid and referred to as function-valued traits. Both physiological a…
NLP techniques improve drug discovery by analyzing chemical and protein text.
The ability to inferring latent psychological traits from human behavior is key to developing personalized human-interacting machine learning systems. Approaches to infer such traits range from surveys to manually-constructed experiments and games. However, these traditional games are limited because they are typically…
Interpretable neural network for plant traits and species identification.
New model uses pretrained biochemical language models to generate drug compounds.
GPIRT uses Gaussian processes to estimate latent traits and IRFs from binary responses.
Perceived personality traits attributed to an individual do not have to correspond to their actual personality traits and may be determined in part by the context in which one encounters a person. These apparent traits determine, to a large extent, how other people will behave towards them. Deep neural networks are inc…
Study identifies personality traits from dance movements in music.
A genome-wide association study (GWAS) correlates marker variation with trait variation in a sample of individuals. Each study subject is genotyped at a multitude of SNPs (single nucleotide polymorphisms) spanning the genome. Here we assume that subjects are unrelated and collected at random and that trait values are n…
We present a three-dimensional graph convolutional network (3DGCN), which predicts molecular properties and biochemical activities, based on 3D molecular graph. In the 3DGCN, graph convolution is unified with learning operations on the vector to handle the spatial information from molecular topology. The 3DGCN model ex…
Phylogeny is the field of modelling the temporal discrete dynamics of speciation. Complex models can nowadays be studied using the Approximate Bayesian Computation approach which avoids likelihood calculations. The field's progression is hampered by the lack of robust software to estimate the numerous parameters of the…
MEP-Net uses MEP to generate solutions from limited data.
Two methods use BART to model missing data in leaf photosynthetic trait data.
A new GNN module learns geometric scattering features for better graph classification and feature exploration.
Study presents MMC model for better fitting multiple choice data.
SharedRep-RLHF learns shared traits for diverse groups, improving fairness and performance.
Many biological characteristics of evolutionary interest are not scalar variables but continuous functions. Here we use phylogenetic Gaussian process regression to model the evolution of simulated function-valued traits. Given function-valued data only from the tips of an evolutionary tree and utilising independent pri…
Deep reinforcement learning finds optimal learning policies for adaptive systems.
In many high-throughput experimental design settings, such as those common in biochemical engineering, batched queries are more cost effective than one-by-one sequential queries. Furthermore, it is often not possible to directly choose items to query. Instead, the experimenter specifies a set of constraints that genera…
There has been huge interest in studying human brain connectomes inferred from different imaging modalities and exploring their relationship with human traits, such as cognition. Brain connectomes are usually represented as networks, with nodes corresponding to different regions of interest (ROIs) and edges to connecti…
PerSense assesses personality traits from text for commonsense reasoning.
Chemical networks outperform spiking neural networks in classification tasks.
Ensemble unsupervised anomaly detection using IRT for hidden ground truth.
Standard ChIP-seq peak calling pipelines seek to differentiate biochemically reproducible signals of individual genomic elements from background noise. However, reproducibility alone does not imply functional regulation (e.g., enhancer activation, alternative splicing). Here we present a general-purpose, interpretable …
For precision medicine and personalized treatment, we need to identify predictive markers of disease. We focus on Alzheimer's disease (AD), where magnetic resonance imaging scans provide information about the disease status. By combining imaging with genome sequencing, we aim at identifying rare genetic markers associa…
Study provides long-term EMG data for multi-day biometric authentication.
LLMs can simulate human investment attitudes based on personality traits.
nUDEs use neural networks to model biology without negative values.
SparseChem speeds up ML for small molecules.
We propose a tri-modal architecture to predict Big Five personality trait scores from video clips with different channels for audio, text, and video data. For each channel, stacked Convolutional Neural Networks are employed. The channels are fused both on decision-level and by concatenating their respective fully conne…
Complex biological systems have been successfully modeled by biochemical and genetic interaction networks, typically gathered from high-throughput (HTP) data. These networks can be used to infer functional relationships between genes or proteins. Using the intuition that the topological role of a gene in a network rela…
Consider unsupervised clustering of objects drawn from a discrete set, through the use of human intelligence available in crowdsourcing platforms. This paper defines and studies the problem of universal clustering using responses of crowd workers, without knowledge of worker reliability or task difficulty. We model sto…
DOODLER detects out-of-distribution inputs by reconstructing in-distribution data.
Research has proven that stress reduces quality of life and causes many diseases. For this reason, several researchers devised stress detection systems based on physiological parameters. However, these systems require that obtrusive sensors are continuously carried by the user. In our paper, we propose an alternative a…
Biotech IPOs in Q1 2021: advanced degrees, clinical trials, and IP key.
As more and more people shift their movie watching online, competition between movie viewing websites are getting more and more intense. Therefore, it has become incredibly important to accurately predict a given user's watching list to maximize the chances of keeping the user on the platform. Recent studies have sugge…