The study quantifies geometric differences between axonal branches using splines.
arXiv research
A locally-built, LLM-digested index of recent arXiv papers in quant finance, geometry/topology, and statistical ML — keyword search served straight from SQLite on this machine.
Trend · papers per month
Arboricity of manifolds is explored, with specific results for 2D surfaces.
We study the singularities of the isotropic skeleton of a Weinstein manifold in relation to Nadler's program of arboreal singularities. By deforming the skeleton via homotopies of the Weinstein structure, we produce a Morse-Bott* representative of the Weinstein homotopy class whose stratified skeleton determines its sy…
New groups defined that act on trees without repeating.
Constructs Lagrangian skeleta for curve singularities.
This is the first installment of a book on combinatorial and geometric group theory from the topological point of view. This is a classical subject. The installment contains Chapters 1, 3 and 4, and there are nine chapters in total: 1. Combinatorial Complexes 2. Topological Invariants 3. Coverings 4. Galois Theory 5. G…
Diffusion-weighted MR imaging (DWI) is the only method we currently have to measure connections between different parts of the human brain in vivo. To elucidate the structure of these connections, algorithms for tracking bundles of axonal fibers through the subcortical white matter rely on local estimates of the fiber …
Large bundles of myelinated axons, called white matter, anatomically connect disparate brain regions together and compose the structural core of the human connectome. We recently proposed a method of measuring the local integrity along the length of each white matter fascicle, termed the local connectome. If communicat…
Understanding the connectivity in the brain is an important prerequisite for understanding how the brain processes information. In the Brain/MINDS project, a connectivity study on marmoset brains uses two-photon microscopy fluorescence images of axonal projections to collect the neuron connectivity from defined brain r…
Tractograms are mathematical representations of the main paths of axons within the white matter of the brain, from diffusion MRI data. Such representations are in the form of polylines, called streamlines, and one streamline approximates the common path of tens of thousands of axons. The analysis of tractograms is a ta…
We applied machine learning to predict whether a gene is involved in axon regeneration. We extracted 31 features from different databases and trained five machine learning models. Our optimal model, a Random Forest Classifier with 50 submodels, yielded a test score of 85.71%, which is 4.1% higher than the baseline scor…
We propose a new method for learning deep neural network models that is based on a greedy learning approach: we add one basis function at a time, and a new basis function is generated as a non-linear activation function applied to a linear combination of the previous basis functions. Such a method (growing deep neural …
Proposes a new neural network architecture inspired by biology to improve learning and information flow.
This paper studies structure detection problems in high temperature ferromagnetic (positive interaction only) Ising models. The goal is to distinguish whether the underlying graph is empty, i.e., the model consists of independent Rademacher variables, versus the alternative that the underlying graph contains a subgraph…
Study Morse models for torus algebra related to knot homology.
Configuring deep Spiking Neural Networks (SNNs) is an exciting research avenue for low power spike event based computation. However, the spike generation function is non-differentiable and therefore not directly compatible with the standard error backpropagation algorithm. In this paper, we introduce a new general back…
Decussation improves robustness of 3D neural networks.
Optimization results are one method for understanding neural computation from Nature's perspective and for defining the physical limits on neuron-like engineering. Earlier work looks at individual properties or performance criteria and occasionally a combination of two, such as energy and information. Here we make use …
Diffusion magnetic resonance imaging (dMRI) data allow to reconstruct the 3D pathways of axons within the white matter of the brain as a tractography. The analysis of tractographies has drawn attention from the machine learning and pattern recognition communities providing novel challenges such as finding an appropriat…
The accurate diagnosis and assessment of neurodegenerative disease and traumatic brain injuries (TBI) remain open challenges. Both cause cognitive and functional deficits due to focal axonal swellings (FAS), but it is difficult to deliver a prognosis due to our limited ability to assess damaged neurons at a cellular le…
To accurately analyze changes of anatomical structures in longitudinal imaging studies, consistent segmentation across multiple time-points is required. Existing solutions often involve independent registration and segmentation components. Registration between time-points is used either as a prior for segmentation in a…
In-vivo examination of the physical connectivity of axonal projections through the white matter of the human brain is made possible by diffusion weighted magnetic resonance imaging (dMRI) Analysis of dMRI commonly considers derived scalar metrics such as fractional anisotrophy as proxies for "white matter integrity," a…
Calcium imaging has revolutionized systems neuroscience, providing the ability to image large neural populations with single-cell resolution. The resulting datasets are quite large, which has presented a barrier to routine open sharing of this data, slowing progress in reproducible research. State of the art methods fo…