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arXiv research

A locally-built, LLM-digested index of recent arXiv papers in quant finance, geometry/topology, and statistical ML — keyword search served straight from SQLite on this machine.

168,695 papers · 148 categories

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23466992 · Jun 202019922001200920172026
48 results for automated cell counting

Better neural arithmetic logic units improve cell counting model generalization.

problem Neural networks struggle with high cell counts outside training data range.
method Introduced Neural Arithmetic Logic Units (NALU) for arithmetic operations in existing architectures.
result Improved cell counting accuracy for higher numeric ranges with better generalization.

Automatically counts microglial cells in rat spinal cord images, providing precise counts and uncertainty estimates.

problem Counting microglial cells in small, heterogeneous datasets is time-consuming and requires extensive training.
method Pre-processing to filter images, designing a non-parametric, non-linear kernel counter, providing uncertainty estimation.
result The method can provide precise counts and uncertainty estimates in small datasets, even with expert opinions.

This study automates blood cell classification using computer vision.

problem Automated detection and classification of white blood cells.
method Color-based segmentation, morphological processing, feature extraction, PCA, Unsupervised and Supervised learning algorithms, Deep Convolutional Neural Networks.
result Identification of robust algorithms for automated blood cell classification.

We construct a small regular cellular decomposition of the Fulton MacPherson operad FM2FM_2 that is compatible with the operad composition. The cells are indexed by trees with edges of two colors and vertices labelled by cells of the cacti operad. We compute the generating functions counting the cells, that are algebrai…

2019-06-18abs ↗pdf ↗

TIMELY improves consistency in labeling blood cell images.

problem Inconsistent labeling of blood cells in microscopy images leads to unreliable diagnoses.
method TIMELY combines pseudotime inference and hidden Markov trees to correct labeling mistakes.
result TIMELY outperforms baseline methods in identifying and correcting inconsistent labels.

Method improves microbial biomass yield estimation from noisy data.

problem Estimating microbial biomass yields from noisy cell counts and substrate measurements.
method Probabilistic macrochemical modeling to relax cell weight assumptions and improve robustness.
result Model provides accurate uncertainty estimates of key parameters.

SimCD simultaneously clusters cells and identifies differential gene expression in scRNA-seq data.

problem Separate clustering and differential expression analysis for scRNA-seq data leads to suboptimal results.
method Develops SimCD, a unified hierarchical gamma-negative binomial model for simultaneous cell clustering and differential expression analysis.
result SimCD outperforms existing methods in discovering cell clusters and capturing dynamic expression changes.

In this paper we examine a possible reason for the LSTM outperforming the GRU on language modeling and more specifically machine translation. We hypothesize that this has to do with counting. This is a consistent theme across the literature of long term dependence, counting, and language modeling for RNNs. Using the si…

2018-10-29abs ↗pdf ↗

Each woman living in the United States has about 1 in 8 chance of developing invasive breast cancer. The mitotic cell count is one of the most common tests to assess the aggressiveness or grade of breast cancer. In this prognosis, histopathology images must be examined by a pathologist using high-resolution microscopes…

2020-02-01abs ↗pdf ↗

Counting is a fundamental task in biomedical imaging and count is an important biomarker in a number of conditions. Estimating the uncertainty in the measurement is thus vital to making definite, informed conclusions. In this paper, we first compare a range of existing methods to perform counting in medical imaging and…

2019-07-25abs ↗pdf ↗

Flow Matching for count data improves sample quality and efficiency.

problem Mapping between count distributions across batches or time points in high-dimensional count data.
method count-FM, a flow-matching framework based on a continuous-time birth-death process with local unit jumps.
result count-FM achieves better sample quality than representative baselines while using fewer parameters.

Researchers found all embeddings of Kuratowski graphs on a double torus.

problem Characterizing embeddings of Kuratowski graphs K3,3K_{3,3} and K5K_5 on the double torus.
method Constructive approach using Burnside's Lemma and automorphism groups.
result 14 orientable and 17 non-orientable 2-cell embeddings of K5K_5 on the double torus.

New model generates realistic single-cell gene expression data.

problem Generating realistic single-cell gene expression profiles is challenging.
method scLDM, a latent diffusion model using Diffusion Transformers and linear interpolants.
result Superior performance in generating realistic single-cell gene expression data.

Researchers infer gene activity in dividing cells, accounting for protein inheritance and division history.

problem Inferring protein production kinetics in dividing cells due to protein inheritance and division history.
method Adapted conditional normalizing flows to approximate intractable likelihoods from simulated data.
result Glc3 gene is mostly inactive under stress, with brief and transient expression.

In this brief sequel to a previous article, we recall the notion of a cut cellular surface (CCS), being a surface with boundary, which is cut in a specified way to be represented in the plane, and is composed of 0-, 1- and 2-cells. We obtain invariants of CCS's under Pachner-like moves on the cellular structure, by cou…

2017-10-04abs ↗pdf ↗

Recently V. Krushkal and D. Renardy generalized the Tutte polynomial from graphs to cell complexes. We show that evaluating this polynomial at the origin gives the number of cellular spanning trees in the sense of A. Duval, C. Klivans, and J. Martin. Moreover, after a slight modification, the Tutte-Krushkal-Renardy pol…

2012-04-16abs ↗pdf ↗

Analysis of flow cytometry data is an essential tool for clinical diagnosis of hematological and immunological conditions. Current clinical workflows rely on a manual process called gating to classify cells into their canonical types. This dependence on human annotation limits the rate, reproducibility, and complexity …

2017-11-21abs ↗pdf ↗

We introduce the notion of a cut cellular surface (CCS), being a surface with boundary, which is cut in a specified way to be represented in the plane, and is composed of 0-, 1- and 2-cells. We obtain invariants of CCS's under Pachner-like moves on the cellular structure, by counting colourings of the 1-cells with elem…

2015-12-22abs ↗pdf ↗

The paper improves Fisher-Pitman tests for Poisson mixtures, detecting autism-related genes.

problem Detecting differentially expressed genes between autism and control subjects.
method Nonparametric Poisson mixtures and Fisher-Pitman permutation tests.
result The tests reveal genes missed by common methods, demonstrating rate optimality.

Multi-domain learning (MDL) aims at obtaining a model with minimal average risk across multiple domains. Our empirical motivation is automated microscopy data, where cultured cells are imaged after being exposed to known and unknown chemical perturbations, and each dataset displays significant experimental bias. This p…

2019-03-21abs ↗pdf ↗

There are various algorithms and methodologies used for automated screening of cervical cancer by segmenting and classifying cervical cancer cells into different categories. This study presents a critical review of different research papers published that integrated AI methods in screening cervical cancer via different…

2018-11-02abs ↗pdf ↗

The exponential growth of complex data demands fully automatic clustering. Gaussian mixture models (GMMs) provide uncertainty-aware grouping but often require expertise to specify hyperparameters, e.g., component count and covariance structure. While mclust (R) automates this via Bayesian Information Criterion (BIC), P…

2019-09-06abs ↗pdf ↗

USP test improves on Pearson's chi-squared and GG-test for independence.

problem Deficiencies in Pearson's chi-squared and GG-test for independence.
method USP test based on UU-statistic estimator of population dependence measure.
result USP test controls size, handles small cell counts, and detects minimal violations of independence.

Proposes PSCCA for estimating correlations and canonical correlations in sparse count data.

problem Estimating correlations and canonical correlations in sparse count data from next-generation sequencing.
method Probabilistic approach for sparse count data sets (PSCCA).
result PSCCA outperforms other methods in estimating true correlations and canonical correlations at the natural parameter level.

Deep learning predicts tissue properties from cell-laden hydrogels.

problem Predicting tissue properties from cell-laden hydrogels.
method Developed a process for generating mould designs, created a training set of 6500 cases, trained a deep learning model (pix2pix).
result Deep learning makes excellent predictions and is significantly faster than biophysical methods.

Paper introduces ZIPTF and C-ZIPTF for better tensor factorization of zero-inflated count data.

problem Inefficient tensor factorization for zero-inflated count data, especially in scRNA-seq.
method Zero Inflated Poisson Tensor Factorization (ZIPTF) and Consensus Zero Inflated Poisson Tensor Factorization (C-ZIPTF).
result ZIPTF and C-ZIPTF improve tensor factorization accuracy and consistency for zero-inflated count data.

Develops a tool to identify abnormal blood smear results based on CBC tests.

problem Manual review of blood smears by technologists is time-consuming and inconsistent.
method Cost-sensitive Lasso-penalized additive logistic regression combined with stability selection.
result The tool correctly identifies true cutoff values for abnormal smear results.

Automatic bill classification is an attractive task with many potential applications such as automated detection and counting in images or videos. To address this purpose we present a Deep Learning Model to classify Chilean Banknotes, because of its successful results in image processing applications. For optimal perfo…

2019-12-21abs ↗pdf ↗

DCENWCNet improves WBC classification with LIME-based explainability.

problem Classifying white blood cells from blood images with high accuracy and interpretability.
method Integrates three CNN architectures with different settings to balance feature learning and performance.
result Achieves highest mean accuracy on the Rabbin-WBC dataset, outperforming state-of-the-art networks.

The paper tackles extrapolation of gene knockouts effects on RNA counts.

problem Modeling effects of gene knockouts on RNA counts for new perturbations.
method Formulated as a latent variable model with additive perturbation effects, proved identifiability, proposed PDAE for estimation.
result PDAE can accurately predict effects of unseen but identifiable perturbations.

A novel method detects multiple mitosis events and mitigates annotation gaps in phase-contrast microscopy.

problem Detecting multiple mitosis events and handling annotation gaps in closely placed cells.
method Estimating a spatiotemporal likelihood map via 3DCNN to detect multiple mitosis events and mitigate annotation gaps.
result Our method outperformed compared methods in terms of F1-score using a challenging dataset.

Cilia are hairlike structures protruding from nearly every cell in the body. Diseases known as ciliopathies, where cilia function is disrupted, can result in a wide spectrum of disorders. However, most techniques for assessing ciliary motion rely on manual identification and tracking of cilia; this process is laborious…

2018-03-20abs ↗pdf ↗

The study analyzes local minima in ReLU networks and finds low probability of bad local minima.

problem Understanding the existence and probability of local minima in ReLU networks.
method Theoretical analysis combined with linear programming and experiments on MNIST and CIFAR-10 datasets.
result No bad differentiable local minima found almost everywhere in weight space.