Better neural arithmetic logic units improve cell counting model generalization.
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Automatically counts microglial cells in rat spinal cord images, providing precise counts and uncertainty estimates.
This study automates blood cell classification using computer vision.
Foraminifera are single-celled marine organisms, which may have a planktic or benthic lifestyle. During their life cycle they construct shells consisting of one or more chambers, and these shells remain as fossils in marine sediments. Classifying and counting these fossils have become an important tool in e.g. oceanogr…
We construct a small regular cellular decomposition of the Fulton MacPherson operad that is compatible with the operad composition. The cells are indexed by trees with edges of two colors and vertices labelled by cells of the cacti operad. We compute the generating functions counting the cells, that are algebrai…
TIMELY improves consistency in labeling blood cell images.
Method improves microbial biomass yield estimation from noisy data.
SimCD simultaneously clusters cells and identifies differential gene expression in scRNA-seq data.
In this paper we examine a possible reason for the LSTM outperforming the GRU on language modeling and more specifically machine translation. We hypothesize that this has to do with counting. This is a consistent theme across the literature of long term dependence, counting, and language modeling for RNNs. Using the si…
Each woman living in the United States has about 1 in 8 chance of developing invasive breast cancer. The mitotic cell count is one of the most common tests to assess the aggressiveness or grade of breast cancer. In this prognosis, histopathology images must be examined by a pathologist using high-resolution microscopes…
Motivation: Single cell transcriptome sequencing (scRNA-Seq) has become a revolutionary tool to study cellular and molecular processes at single cell resolution. Among existing technologies, the recently developed droplet-based platform enables efficient parallel processing of thousands of single cells with direct coun…
Counting is a fundamental task in biomedical imaging and count is an important biomarker in a number of conditions. Estimating the uncertainty in the measurement is thus vital to making definite, informed conclusions. In this paper, we first compare a range of existing methods to perform counting in medical imaging and…
Flow Matching for count data improves sample quality and efficiency.
Researchers found all embeddings of Kuratowski graphs on a double torus.
New model generates realistic single-cell gene expression data.
Counting and classifying blood cells is an important diagnostic tool in medicine. Support Vector Machines are increasingly popular and efficient and could replace artificial neural network systems. Here a method to classify blood cells is proposed using SVM. A set of statistics on images are implemented in C++. The MPE…
Researchers infer gene activity in dividing cells, accounting for protein inheritance and division history.
In this brief sequel to a previous article, we recall the notion of a cut cellular surface (CCS), being a surface with boundary, which is cut in a specified way to be represented in the plane, and is composed of 0-, 1- and 2-cells. We obtain invariants of CCS's under Pachner-like moves on the cellular structure, by cou…
Recently V. Krushkal and D. Renardy generalized the Tutte polynomial from graphs to cell complexes. We show that evaluating this polynomial at the origin gives the number of cellular spanning trees in the sense of A. Duval, C. Klivans, and J. Martin. Moreover, after a slight modification, the Tutte-Krushkal-Renardy pol…
Analysis of flow cytometry data is an essential tool for clinical diagnosis of hematological and immunological conditions. Current clinical workflows rely on a manual process called gating to classify cells into their canonical types. This dependence on human annotation limits the rate, reproducibility, and complexity …
We introduce the notion of a cut cellular surface (CCS), being a surface with boundary, which is cut in a specified way to be represented in the plane, and is composed of 0-, 1- and 2-cells. We obtain invariants of CCS's under Pachner-like moves on the cellular structure, by counting colourings of the 1-cells with elem…
Develops a new neural spike train decoding framework using topological data.
New hypergraph method improves scRNA-seq clustering.
The paper improves Fisher-Pitman tests for Poisson mixtures, detecting autism-related genes.
Gatherings of thousands to millions of people frequently occur for an enormous variety of events, and automated counting of these high-density crowds is useful for safety, management, and measuring significance of an event. In this work, we show that the regularly accepted labeling scheme of crowd density maps for trai…
Multi-domain learning (MDL) aims at obtaining a model with minimal average risk across multiple domains. Our empirical motivation is automated microscopy data, where cultured cells are imaged after being exposed to known and unknown chemical perturbations, and each dataset displays significant experimental bias. This p…
This article introduces planar ribbons, Vergili ribbon complexes and ribbon nerves in Alexandroff-Hopf-Whitehead CW (Closure finite Weak) topological spaces. A {\em planar ribbon} (briefly, {ribbon}) in a CW space is the closure of a pair of nesting, non-concentric filled cycles that includes the boundary but does not …
There are various algorithms and methodologies used for automated screening of cervical cancer by segmenting and classifying cervical cancer cells into different categories. This study presents a critical review of different research papers published that integrated AI methods in screening cervical cancer via different…
The exponential growth of complex data demands fully automatic clustering. Gaussian mixture models (GMMs) provide uncertainty-aware grouping but often require expertise to specify hyperparameters, e.g., component count and covariance structure. While mclust (R) automates this via Bayesian Information Criterion (BIC), P…
The challenge in controlling stochastic systems in which low-probability events can set the system on catastrophic trajectories is to develop a robust ability to respond to such events without significantly compromising the optimality of the baseline control policy. This paper presents CelluDose, a stochastic simulatio…
USP test improves on Pearson's chi-squared and -test for independence.
Proposes PSCCA for estimating correlations and canonical correlations in sparse count data.
This article introduces vortex nerve complexes in CW (Closure finite Weak) topological spaces, which first appeared in works by P. Alexandroff, H. Hopf and J.H.C. Whitehead during the 1930s. A vortex nerve is a CW complex containing one or more intersecting path-connected cycles. Each vortex nerve has its own distincti…
Deep learning predicts tissue properties from cell-laden hydrogels.
Manual count of mitotic figures, which is determined in the tumor region with the highest mitotic activity, is a key parameter of most tumor grading schemes. It can be, however, strongly dependent on the area selection due to uneven mitotic figure distribution in the tumor section.We aimed to assess the question, how s…
High-throughput sequencing allows the detection and quantification of frequencies of somatic single nucleotide variants (SNV) in heterogeneous tumor cell populations. In some cases, the evolutionary history and population frequency of the subclonal lineages of tumor cells present in the sample can be reconstructed from…
Paper introduces ZIPTF and C-ZIPTF for better tensor factorization of zero-inflated count data.
Due to globalization, geographic boundaries no longer serve as effective shields for the spread of infectious diseases. In order to aid bio-surveillance analysts in disease tracking, recent research has been devoted to developing information retrieval and analysis methods utilizing the vast corpora of publicly availabl…
Develops a tool to identify abnormal blood smear results based on CBC tests.
Automatic bill classification is an attractive task with many potential applications such as automated detection and counting in images or videos. To address this purpose we present a Deep Learning Model to classify Chilean Banknotes, because of its successful results in image processing applications. For optimal perfo…
DCENWCNet improves WBC classification with LIME-based explainability.
Artificial intelligence offers the potential to automate challenging data-processing tasks in collider physics. To establish its prospects, we explore to what extent deep learning with convolutional neural networks can discriminate quark and gluon jets better than observables designed by physicists. Our approach builds…
Biology has changed radically in the last two decades, transitioning from a descriptive science into a design science. Synthetic biology allows us to bioengineer cells to synthesize novel valuable molecules such as renewable biofuels or anticancer drugs. However, traditional synthetic biology approaches involve ad-hoc …
The paper tackles extrapolation of gene knockouts effects on RNA counts.
A novel method detects multiple mitosis events and mitigates annotation gaps in phase-contrast microscopy.
Cilia are hairlike structures protruding from nearly every cell in the body. Diseases known as ciliopathies, where cilia function is disrupted, can result in a wide spectrum of disorders. However, most techniques for assessing ciliary motion rely on manual identification and tracking of cilia; this process is laborious…
The study analyzes local minima in ReLU networks and finds low probability of bad local minima.
We explore solutions for automated labeling of content in bug trackers and customer support systems. In order to do that, we classify content in terms of several criteria, such as priority or product area. In the first part of the paper, we provide an overview of existing methods used for text classification. These met…