As datasets grow richer, an important challenge is to leverage the full features in the data to maximize the number of useful discoveries while controlling for false positives. We address this problem in the context of multiple hypotheses testing, where for each hypothesis, we observe a p-value along with a set of feat…
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48 results for “association discovery”
Tensor-based method simplifies causal skeleton discovery.
problem Discover causal relationships between variables.
method Express associations as tensors to reduce dimensionality.
result Causal skeleton can be determined using pair-wise tensors.
New method discovers nonlinear associations using copula entropy.
problem Linear association measures have theoretical limitations.
method Proposes a new method using copula entropy.
result Demonstrates more meaningful nonlinear associations.
Scientific discovery is limited by hypothesis redundancy, and hybrid methods can exploit non-local exploration.
problem Limitation of scientific discovery due to hypothesis redundancy.
method Hybrid discovery systems combining structured local search with LLM-generated non-local proposals.
result Hybrid methods can exploit non-local exploration when three geometric conditions co-occur.
CardiGraphormer: Unveiling the Power of Self-Supervised Learning in Revolutionizing Drug Discoverycs.LG
CardiGraphormer uses SSL and GNNs to improve drug discovery.
problem Challenges in drug discovery due to combinatorial chemical space and limited approved drugs.
method Combines self-supervised learning, Graph Neural Networks, and Cardinality Preserving Attention.
result Enhanced predictive performance and interpretability in drug discovery.
Enhances FDR control in variable selection using neural networks.
problem Balancing rigorous error control with statistical power in high-dimensional variable selection.
method Learning-augmented T-Rex Selector framework with a neural network trained on synthetic datasets.
result Achieves superior detection of true variables compared to existing approaches.
LORL learns object-centric representations from vision and language.
problem Learning disentangled, object-centric scene representations from vision and language.
method LORL integrates unsupervised object discovery and segmentation with language input to learn object-centric concepts.
result LORL improves unsupervised object discovery methods and aids downstream tasks.
Transforming Causality: Transformer-Based Temporal Causal Discovery with Prior Knowledge Integrationcs.LG
Transformer-based method for causal discovery with prior knowledge integration.
problem Complex nonlinear dependencies and spurious correlations in time series data.
method Multi-layer Transformer forecaster with gradient-based causal structure extraction and attention masking for prior knowledge integration.
result Significant improvement in causal discovery and causal lag estimation compared to state-of-the-art methods.
Framework isolates causal effects from time series data, improving accuracy under non-stationarity and autocorrelation.
problem Causal inference in non-stationary, autocorrelated time series data.
method Decomposes time series into trend, seasonal, and residual components; performs component-specific causal analysis.
result Framework more accurately recovers ground-truth causal structure than state-of-the-art baselines, especially under strong non-stationarity and temporal autocorrelation.
Framework detects anomalies in industrial processes using deep learning.
problem Detect anomalies in complex industrial processes.
method Causal-based framework with unsupervised deep learning.
result Successfully validated abstract contexts of blast furnace assets.
Generates synthetic manufacturing data for causal discovery benchmarking.
problem Lack of suitable real data for validating causal discovery algorithms.
method Distributional random forests for estimating conditional distributions.
result Semisynthetic manufacturing data adheres to a causal model.
The paper studies scaling laws for associative memory mechanisms.
problem Understanding and optimizing learning and memorization processes.
method High-dimensional matrices of outer products of embeddings, relating to transformer models. Derived scaling laws with sample and parameter sizes. Extensive numerical experiments.
result Precise scaling laws and statistical efficiency of estimators.
DEX allows HFTs to quickly acquire speed, improving price discovery without sacrificing liquidity.
problem Low-latency trading's externality and resource inefficiency in centralized exchanges.
method Model of decentralized exchanges with real-time speed acquisition from peer-to-peer networks.
result HFTs on DEX acquire more speed for shorter timespans, decreasing price discovery time and reducing resource lock-in.
The Informed Elastic Net for Fast Grouped Variable Selection and FDR Control in Genomics Researchstat.ME
IEN speeds up T-Rex+GVS for fast, efficient GWAS.
problem Efficiently selecting groups of genetic variants in large-scale genomics studies.
method Informed Elastic Net (IEN) as a faster base selector for T-Rex+GVS.
result IEN reduces computation time while maintaining high TPR and FDR control.
QPE identifies causal effects without assuming mechanisms or noise.
problem Identifying causal relationships from observational data.
method Quantile Partial Effect (QPE) and Fisher Information.
result Causal directions can be distinguished using QPE and Fisher Information.
Extends linear structural causal models to include deterministic relations and latent confounders for causal discovery.
problem Causal discovery in linear SCMs with deterministic relations and latent confounders.
method Extended existing results to include deterministic relations and latent confounders, derived necessary and sufficient conditions for unique identifiability, proposed an algorithm for recovery.
result First work on identifiability results for causal discovery under latent confounding and deterministic relationships.
GeneDisco benchmarks experimental design for drug discovery.
problem Vast experimental design space in drug discovery.
method Machine learning for optimal experimental design.
result Standardised benchmark suite for active learning.
New method identifies causal order without sparsity assumptions.
problem Causal order discovery in observational data.
method Sequential procedure to directly identify causal order.
result Direct identification of causal order without sparsity assumptions.
Causal discovery algorithms can help generate legal arguments.
problem Leveraging causal discovery algorithms in legal decision-making.
method Prepared a legal dataset, annotated with 17 legal concepts, applied causal discovery algorithms, and quantified degrees of belief.
result Some causal relationships help generate viable legal arguments.
Automated digital twin discovery from biological data improves drug discovery and personalized medicine.
problem Developing reliable digital twins from noisy, incomplete biological data.
method Symbolic and sparse regression, Bayesian frameworks, deep learning, and large language models.
result Sparse regression generally outperforms symbolic regression, especially with Bayesian frameworks.
FSR efficiently discovers significant patterns with few resampled datasets.
problem Mining significant patterns in transactional data, especially subgroups.
method FSR uses resampling to bound the supremum deviation of quality statistics, providing rigorous guarantees on false discoveries.
result FSR effectively discovers significant subgroups with a small number of resampled datasets.
New method uses path signatures for causal discovery in time series data.
problem Challenges in understanding causal structure from observational time series data.
method Path signatures and signed areas for model-free causal discovery.
result Confidence sequence regions help identify lag/lead causal relationships.
The paper proposes a probabilistic autoencoder for discovering causal directions between variables.
problem Finding the causal direction between two associated variables.
method Building an autoencoder of the joint distribution and maximizing its estimation capacity relative to marginal distributions.
result The higher estimation capacity is consistent with the unconstrained choice of a distribution representing the cause, while the lower capacity reflects the constraints imposed by the mechanism on the distribution of the effect.
DataLearner simplifies data mining on Android devices.
problem Lack of general-purpose data-mining tools for mobile devices.
method Augments Weka engine with Charles Sturt University algorithms, providing 40 mining algorithms.
result Delivers classification accuracy similar to PCs/laptops with acceptable speed and battery life.
Towards Dynamic Causal Discovery with Rare Events: A Nonparametric Conditional Independence Teststat.ML
New test uncovers causal links in rare event dynamics.
problem Causal discovery for rare event phenomena in dynamic systems.
method Nonparametric conditional independence test on time-invariant data.
result Validated across simulated and real-world datasets.
ChatGPT snapshots predict future stock returns.
problem Predicting future stock returns using pre-cutoff text.
method Extracted LLM outlook scores from OpenAI snapshots.
result Outlook scores positively correlate with future stock returns.
fcHMRF-LIS controls FDR in neuroimaging data, improving power and scalability.
problem Complex spatial dependencies and high variability in FDR control methods for neuroimaging data.
method fcHMRF-LIS integrates LIS-based testing with fcHMRF to model spatial structures efficiently.
result fcHMRF-LIS achieves accurate FDR control, lower FNR, and higher true positives compared to existing methods.
This paper deals with the binary classification task when the target class has the lower probability of occurrence. In such situation, it is not possible to build a powerful classifier by using standard methods such as logistic regression, classification tree, discriminant analysis, etc. To overcome this short-coming o…
Federated learning improves bioinformatics by sharing data legally.
problem Lack of access to diverse data in bioinformatics.
method Combines data from multiple institutions legally.
result Federated learning accelerates clinical discovery and robust exploration.
The paper develops methods for high-dimensional inference in Markov random fields.
problem Statistical inference for high-dimensional Markov random fields.
method Markov Chain Monte Carlo Maximum Likelihood Estimation (MCMC-MLE) with Elastic-net regularization.
result The proposed methods achieve -consistency and false discovery rate control.
Differentiable causal discovery methods perform robustly under model violations.
problem Causal discovery algorithms struggle with real-world data due to unverifiable causal assumptions.
method Benchmarked differentiable causal discovery methods under eight model assumption violations.
result Differentiable causal discovery methods exhibit robust performance under Structural Hamming Distance and Structural Intervention Distance metrics.
New framework uses background knowledge to speed up causal discovery.
problem Scalable causal discovery for large datasets.
method Utilizes background knowledge during causal discovery process.
result Background knowledge reduces computational requirements and improves structure quality.
This paper investigates the equivalence between Yamada polynomial and Jones polynomial of associated links for brunnian θ-curves.
problem Understanding the relationship between Yamada polynomial and Jones polynomial for θ-curves.
method Investigates the equivalence between the normalized Yamada polynomial of θ-curves and the Jones polynomial of their associated links.
result Shows that the two polynomials are equivalent for brunnian θ-curves.
New method prevents invalid inference after causal discovery.
problem Invalid inference after causal discovery.
method Developed tools for valid post-causal-discovery inference.
result Our method provides reliable coverage while achieving more accurate causal discovery.
Conformal Prediction Regions match Imprecise Highest Density Regions under consonance.
problem Matching conformal prediction regions with highest density regions.
method Using consonance and the Imprecise Probability theory of clouds.
result Imprecise Highest Density Regions are equivalent to Conformal Prediction Regions under consonance.
Local Discovery by Partitioning: Polynomial-Time Causal Discovery Around Exposure-Outcome Pairsstat.ML
LDP speeds up causal discovery by partitioning, improving VAS recall and runtime.
problem Hard causal discovery in nonparametric settings with exponential complexity.
method Local Discovery by Partitioning (LDP) for causal inference around exposure-outcome pairs.
result LDP yields less biased and more precise estimates than baseline methods.
New method learns temporal abstractions by defining interest functions.
problem Learning temporal abstractions with limited, variable durations.
method Introduced interest functions to define initiation sets, enabling gradient-based learning.
result Demonstrated effectiveness in discrete and continuous environments.
Genome-wide association studies (GWASs) aim to detect genetic risk factors for complex human diseases by identifying disease-associated single-nucleotide polymorphisms (SNPs). The traditional SNP-wise approach along with multiple testing adjustment is over-conservative and lack of power in many GWASs. In this article, …
T-Rex selector selects variables fast and controls FDR in high-dimensional data.
problem Variable selection in high-dimensional data with FDR control.
method Fused solutions of early terminated random experiments.
result FDR control at target level with high variable selection power.
Proposes LLM-DCD for improved causal discovery from data.
problem Challenges in discovering causal relationships from observational data.
method Uses LLM to initialize DCD optimization, incorporating priors.
result Higher accuracy on benchmark datasets compared to state-of-the-art.
Probabilistic grammars improve equation discovery from data.
problem Discovering scientific laws from data using equations.
method Proposed probabilistic context-free grammars to encode soft constraints and a Monte-Carlo algorithm.
result Probabilistic grammars lead to more efficient equation discovery.
The options framework in reinforcement learning models the notion of a skill or a temporally extended sequence of actions. The discovery of a reusable set of skills has typically entailed building options, that navigate to bottleneck states. This work adopts a complementary approach, where we attempt to discover option…
Causal discovery improves fMRI analysis, but faces challenges.
problem Challenges in applying causal discovery to fMRI data.
method Identifying and addressing nine challenges in fMRI causal discovery.
result Current methods for fMRI causal discovery need improvement.
Paper characterizes causal graphs from hard interventions and proposes a learning algorithm.
problem Discovering causal structure from hard interventions and observational data.
method Proposes graphical constraints and a learning algorithm based on do-calculus.
result Characterizes interventional equivalence classes of causal graphs with latent variables.
This work discovers algebraic structures from data using a differentiable measure.
problem Discovering discrete algebraic rules from data.
method Formalizes the problem through Cayley-table completion and uses HyperCube operator-valued tensor factorization.
result Derives an absolute lower bound for the differentiable measure of algebraic complexity, proving it is attained only for group structures.
New methods for Markov Blanket discovery using MML outperform existing approaches.
problem Causal discovery from large datasets.
method Developed three new methods of Markov Blanket discovery using Minimum Message Length.
result Our best MML method is consistently competitive and has advantageous features.
L2D-CD learns to defer expert recommendations in causal discovery.
problem Combining expert knowledge with data-driven results in causal discovery when expert recommendations may contradict data.
method Adapting learning-to-defer algorithms for pairwise causal discovery, L2D-CD learns a deferral function to select between expert recommendations and data-driven methods.
result L2D-CD outperforms both causal discovery methods and the expert used in isolation, identifying domains where the expert's performance is strong or weak.
Review of automation's role in chemical discovery, emphasizing future challenges.
problem Improving automation's contribution to chemical discovery.
method Analysis of exemplary studies and open research directions.
result Future autonomous systems need improvement in data handling, model building, and experiment automation.