Paper tackles toxic comment detection using deep learning.
problem Automatic detection of toxic comments on the internet.
method Designs binary classification and regression-based approaches using DNN.
result BERT fine-tuning outperforms other methods.
The study evaluates 62 classifiers for detecting online toxic comments.
problem Identifying and classifying toxic online commentary.
method Systematic evaluation of 62 classifiers representing 19 algorithmic families on the Jigsaw dataset.
result Simple bad word lists are most predictive of offensive commentary.
CondMTL improves toxicity detection by learning group-specific representations.
problem Algorithmic bias in toxic language detection across demographic groups.
method Conditional Multi-Task Learning (CondMTL) for demographic-specific tasks.
result CondMTL improves predictive recall for minority demographic groups.
Paper develops a fast Bayesian method to predict toxic trades in financial transactions.
problem Predicting and managing toxic trades in financial transactions.
method PULSE: an online learning Bayesian procedure for neural networks.
result Neural networks trained with PULSE outperform traditional methods in predicting toxic trades.
New framework controls statistical dispersion for high-stakes applications.
problem Understanding and controlling the dispersion of loss distributions in high-stakes applications.
method Simple yet flexible framework for distribution-free control of statistical dispersion measures.
result Proposed methods control statistical dispersion measures with societal implications.
Researchers develop method to protect against 'weight poisoning' attacks on pre-trained models.
problem The security threat of downloading untrusted pre-trained weights that can be manipulated after fine-tuning.
method RIPPLe regularization method and Embedding Surgery initialization procedure.
result Demonstrated that weight poisoning attacks are possible even with limited knowledge of the dataset and fine-tuning procedure.
Multimodal deep learning improves toxicity prediction accuracy.
problem Improving prediction accuracy of chemical compound toxicity.
method Combining multiple neural network types and data representations.
result Significantly better accuracy on a toxicity benchmark.
We propose the development of a prediction market for forecasting prices for "toxic assets" to be transferred from Irish banks to the National Asset Management Agency (NAMA). Such a market allows market participants to assume a stake in a security whose value is tied to a future event. We propose that securities are cr…
Timely assessment of compound toxicity is one of the biggest challenges facing the pharmaceutical industry today. A significant proportion of compounds identified as potential leads are ultimately discarded due to the toxicity they induce. In this paper, we propose a novel machine learning approach for the prediction o…
Everyday we are exposed to various chemicals via food additives, cleaning and cosmetic products and medicines -- and some of them might be toxic. However testing the toxicity of all existing compounds by biological experiments is neither financially nor logistically feasible. Therefore the government agencies NIH, EPA …
We refine toxicity bounds for dynamic liquidation incentives in CP-AMM systems.
problem Ensuring stability in dynamic liquidation incentives in automated market makers.
method Derived state-dependent toxicity bounds for dynamic liquidation incentives, reconciling them with CP-AMM price dynamics.
result State-dependent bounds and liquidity-depth-only condition for dynamic liquidation incentives.
Simple machine learning models achieve high accuracy in toxicity prediction.
problem Toxicity prediction of chemical compounds using complex models.
method Using shallow neural networks and decision trees with 2D features.
result Achieves similar or better performance than deep neural networks with less computing time.
Model optimizes trading strategy with unobservable toxicity.
problem Maximizing daily trading profit with unobservable toxicity.
method Formulated as a partially observable stochastic control problem, solved in two steps.
result P&L performance gap is negligible (0.01%) in all scenarios.
This research secures deployed sentiment analysis models by identifying and defending against attack vectors.
problem Securing deployed machine learning models, particularly sentiment analysis systems, from adversarial attacks.
method BAD (Build, Attack, Defend) Architecture, evaluating two implementations.
result Demonstrated a viable methodology for securing machine learning models in production.
SEEDA optimizes dose allocation in clinical trials to balance efficacy and safety.
problem Complex relationships between efficacy and toxicity in new drug trials.
method Adaptive clinical trial methodology that maximizes cumulative efficacy while ensuring safety constraints.
result SEEDA outperforms existing methods in finding optimal doses with higher success rates and fewer patients.
New method designs antimicrobial peptides with high potency and low toxicity.
problem Designing potent antimicrobial drugs with low toxicity.
method CLaSS method using deep generative autoencoder and atomistic simulations.
result Design and synthesis of two novel AMPs with high potency and low toxicity.
The paper proposes a method to evaluate ML models for subjective inference, focusing on sentence toxicity.
problem Bias in ML models for subjective inference, especially in real-life applications.
method Proposes a list of specifications to evaluate ML models for subjective inference, illustrated with a sentence toxicity example.
result Demonstrates the importance of considering subjectivity and bias in evaluating ML models.
This paper compares feature selection methods for biomarker discovery in toxicant-treated fish.
problem Choosing the most suitable method for biomarker discovery in toxicant exposure studies.
method Three feature selection methods: SAM, mRMR, and GeoDE are compared.
result Different methods perform better in different cases, requiring dataset-specific decisions.
Many modern data sets are sampled with error from complex high-dimensional surfaces. Methods such as tensor product splines or Gaussian processes are effective/well suited for characterizing a surface in two or three dimensions but may suffer from difficulties when representing higher dimensional surfaces. Motivated by…
Toxicity analysis and prediction are of paramount importance to human health and environmental protection. Existing computational methods are built from a wide variety of descriptors and regressors, which makes their performance analysis difficult. For example, deep neural network (DNN), a successful approach in many o…
This paper improves bond market making by adjusting hit-ratios for client flow quality.
problem Economic misleading of raw hit-ratios in corporate bond market making.
method Stochastic-control framework with residual-quality-adjusted hit-ratio.
result Optimal quotes decompose into various components, improving service/economics frontier.
Bayesian framework improves minority class performance in class-imbalanced data.
problem Class imbalance in predictive toxicology models.
method Weighted likelihood approach modifying likelihood function weights inversely proportional to class proportions.
result Improves balanced accuracy and sensitivity for minority class (toxic compounds).
CogMol designs novel drug-like molecules for SARS-CoV-2 targets.
problem Designing efficient drugs for novel viral proteins.
method End-to-end framework combining VAE, controlled sampling, and predictors.
result Highly selective and affinity molecules for SARS-CoV-2 targets.
Financial institutions face new model risks with AI, requiring enhanced model risk management.
problem New model risks from Generative AI applications in financial institutions.
method Enhanced model risk framework with additional testing and controls.
result Financial institutions need to enhance their model risk management for Generative AI applications.
Shared Keyboard design improves phase I clinical trials by borrowing information across doses.
problem Interim decisions based on current dose data may overlook signals from neighboring doses.
method Bayesian model-assisted design using Beta kernel process with kernel-weighted pseudo-counts.
result Significant improvements in identifying maximum tolerated dose and safety.
UBM transfers bias mitigation from upstream to downstream tasks efficiently.
problem Bias in fine-tuned language models across various tasks.
method Apply bias mitigation to an upstream model, then fine-tune a downstream model on this mitigated model.
result UBM effects transfer to new downstream tasks, creating less biased models.
In this paper, we study counterfactual fairness in text classification, which asks the question: How would the prediction change if the sensitive attribute referenced in the example were different? Toxicity classifiers demonstrate a counterfactual fairness issue by predicting that "Some people are gay" is toxic while "…
Deep learning model tackles illegal comments with promising results.
problem Lack of labeled data in legal domain.
method Multi-task deep learning model for classification.
result Promising results in classifying illegal comments.
Enhances graph classification models on small datasets.
problem Over-fitting and undergeneralization on small-scale benchmark datasets.
method Data augmentation via graph structure transformation and model evolution framework.
result Average improvement of 3 - 13% accuracy on graph classification tasks.
Mitigates bias in text classification by weighting instances.
problem Unintended biases in text classification datasets based on demographic terms.
method Instance weighting to recover non-discrimination distribution.
result Effective mitigation of unintended biases without sacrificing generalization.
Several social, medical, engineering and biological challenges rely on discovering the functionality of networks from their structure and node metadata, when it is available. For example, in chemoinformatics one might want to detect whether a molecule is toxic based on structure and atomic types, or discover the resear…
In the last few years, we have seen the transformative impact of deep learning in many applications, particularly in speech recognition and computer vision. Inspired by Google's Inception-ResNet deep convolutional neural network (CNN) for image classification, we have developed "Chemception", a deep CNN for the predict…
The meteoric rise of deep learning models in computer vision research, having achieved human-level accuracy in image recognition tasks is firm evidence of the impact of representation learning of deep neural networks. In the chemistry domain, recent advances have also led to the development of similar CNN models, such …
HRL improves open-domain dialog models by optimizing long-term conversational goals.
problem Challenges in open-domain dialog generation, including repetitive outputs, difficulty tracking conversational goals, and inappropriate text.
method Proposes VHRL, a hierarchical reinforcement learning approach using policy gradients to tune utterance-level embeddings of a variational sequence model.
result Significant improvements in human evaluation and automatic metrics over state-of-the-art dialog models.
JIT liquidity providers can sometimes reduce overall market liquidity by crowding out passive LPs.
problem JIT liquidity providers can reduce overall market liquidity by crowding out passive LPs.
method Game-theoretic model with asymmetrically informed agents to analyze JIT liquidity provision in blockchain-based decentralized exchanges.
result JIT LPs only provide liquidity to uninformed orders and crowd out passive LPs when order volume is not sufficiently elastic to pool depth, potentially reducing overall market liquidity.
New SigSwap model for path-dependent financial risk.
problem Managing complex, path-dependent financial risks.
method Geometry-based approach using path-signature and Signature Expected Shortfall.
result Path-dependent risks can be converted into transparent risk factors.
For quantitative structure-property relationship (QSPR) studies in chemoinformatics, it is important to get interpretable relationship between chemical properties and chemical features. However, the predictive power and interpretability of QSPR models are usually two different objectives that are difficult to achieve s…
Proposes a method to generate text that adheres to logical constraints.
problem Generating text that respects logical constraints is hard for autoregressive models.
method Bayesian conditioning to draw samples subject to a constraint, considering the entire sequence and inducing a local, factorized distribution.
result Our approach generates samples that closely approximate the target distribution and are guaranteed to satisfy the constraints.
FLAIR measures LP competitiveness in AMMs, improving LP performance evaluations.
problem LP returns are affected by both market risk and competitive strategies.
method Introduces FLAIR metric to quantify LP competitiveness and assesses its impact on LP returns.
result FLAIR captures dynamic behavior of LPs and differentiates between active provisioning strategies.
Proposes semi-supervised feature ranking for handling high-dimensional, unlabeled data.
problem Handling high-dimensional, unlabeled data in machine learning.
method Tree ensembles and Relief family algorithms for semi-supervised feature ranking.
result Semi-supervised feature ranking outperforms supervised methods across most datasets.
Machine learning helps predict smoke types for safer forest burns.
problem Determining which fuels to burn safely to reduce wildfire risk and minimize smoke.
method Machine learning techniques like spectral clustering and manifold learning.
result Interpretable representations and tools for differentiating smoke types.
Bayesian methods improve drug discovery experiment design.
problem Optimizing drug screening experiments in high-dimensional data.
method Bayesian inference and optimisation with upper confidence bound algorithms, Thompson sampling, and sparse tree search.
result Sparse tree search techniques outperform other methods in drug toxicity screening.
LLMs struggle with zero-shot annotation tasks due to model-internalized priors.
problem Impact of model-internalized priors on LLM performance in zero-shot annotation tasks.
method Investigated three dimensions: familiarity, decision stickiness, and susceptibility to misaligned task definitions.
result Nearly two-thirds of zero-shot errors are resistant to correction, with a rescue rate of 34.8%. Definition-Specific Familiarity (DSF) shows a positive association with model performance.
A simple strategy optimizes broker-client trading, reducing price discounts for informed traders.
problem Optimizing broker-client trading to balance client flow and informed trader losses.
method Modelled as a stochastic control problem, derived optimal strategy in closed form, introduced algorithm.
result Optimal strategy reduces price discounts for informed traders, balancing client flow and informed trader losses.
Causal ML predicts treatment outcomes, aiding personalized medicine.
problem Predicting individualized treatment effects for personalized medicine.
method Flexible, data-driven methods using causal inference with clinical trial and real-world data.
result Causal ML allows for estimating individualized treatment effects.
The paper examines statistical properties of IL and LVR in automated market makers.
problem Assessing the performance of automated market makers and their profitability.
method Analysis of random walk properties and statistical integral combined with CFMM mechanics.
result IL and LVR have identical expectation values but different distribution functions for Brownian motion.
Study uses Thompson Sampling to find optimal drug dosages in clinical trials.
problem Finding the best drug dosage in early-stage clinical trials.
method Adopted Thompson Sampling for dose-finding clinical trials, considering different monotonicity assumptions.
result Thompson Sampling variants outperform existing methods in various dose-finding scenarios.
High Frequency Trading (HFT) represents an ever growing proportion of all financial transactions as most markets have now switched to electronic order book systems. The main goal of the paper is to propose continuous time equations which generalize the self-financing relationships of frictionless markets to electronic …