Smooth Schrödinger Bridges improve trajectory inference by smoothing Gaussian processes.
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problem Improving trajectory inference in applications like particle tracking.
method Generalizes Schrödinger Bridge problem to smooth Gaussian processes, solving the problem on phase space.
result The method outperforms existing methods on real datasets.
Proposes JACA for joint analysis of multi-view data with class information.
problem Finding associations between multi-view data related to class memberships.
method Joint Association and Classification Analysis (JACA) framework.
result Improved misclassification rates and stronger associations compared to existing methods.
In biological research machine learning algorithms are part of nearly every analytical process. They are used to identify new insights into biological phenomena, interpret data, provide molecular diagnosis for diseases and develop personalized medicine that will enable future treatments of diseases. In this paper we (1…
Fusing heterogeneous data setsq-bio.GN
This thesis tackles data fusion issues across different biological scales and types.
problem Heterogeneity in data types and scales in systems biology.
method Developed statistical methods to fuse heterogeneous data sets.
result Advantages of proposed methods assessed through simulations and real data analysis.
A Graph Feature Auto-Encoder for the Prediction of Unobserved Node Features on Biological Networksq-bio.QM
Graph auto-encoder predicts unobserved node features from biological networks and omics data.
problem Integrating biological networks and continuous node features for better prediction.
method Graph neural networks and feature auto-encoders trained on feature reconstruction.
result Graph feature auto-encoder outperforms auto-encoders trained on graph reconstruction for predicting unobserved node features.