arXiv research

PNNs improve treatment outcomes in TAVR and liver trauma.

Deep learning predicts drug prescriptions across global health records.

A model learns symptom-drug relations for PD patients.

New approach makes deep reinforcement learning robust without assuming adversary knowledge.

Paper integrates predictive and prescriptive tasks using bilevel optimization.

The Prescriptive Canvas improves business outcomes by directly prescribing actions based on predictions.

A new neural network model for optimal treatment assignment.

We address the problem of prescribing an optimal decision in a framework where the cost function depends on uncertain problem parameters that need to be learned from data. Earlier work proposed prescriptive formulations based on supervised machine learning methods. These prescriptive methods can factor in contextual in…

PNNs improve personalized healthcare policies using mixed integer programming.

ODTLearn learns optimal decision trees for predictive and prescriptive tasks.

The opioid epidemic in the United States claims over 40,000 lives per year, and it is estimated that well over two million Americans have an opioid use disorder. Over-prescription and misuse of prescription opioids play an important role in the epidemic. Individuals who are prescribed opioids, and who are diagnosed wit…

The study compares Euclidean and cosine distances in medical drug prescription prediction.

Method learns optimal treatment policies from observational data.

This paper addresses a novel data science problem, prescriptive price optimization, which derives the optimal price strategy to maximize future profit/revenue on the basis of massive predictive formulas produced by machine learning. The prescriptive price optimization first builds sales forecast formulas of multiple pr…

Dynamic treatment recommendation systems based on large-scale electronic health records (EHRs) become a key to successfully improve practical clinical outcomes. Prior relevant studies recommend treatments either use supervised learning (e.g. matching the indicator signal which denotes doctor prescriptions), or reinforc…

Local classification of surfaces and hypersurfaces with radial mean curvature.

Proposes Coherent Gradients to explain and reduce overfitting in neural networks.

Paper solves curvature prescription problem on surfaces with boundary.

P.Lecomte has proposed to take into account the covariant derivatives used to build ordering prescriptions for the naturality of transformation properties and has conjectured that there exists an natural ordering prescription for differential operators of any orders between density bundles which in addition is invarian…

The paper integrates AI and expert knowledge to optimize radiotherapy decisions.

New approach for estimating individual treatment effects in low compliance settings.

Prescribing, by conformal transformation, the kth-elementary symmetric polynomial of the Schouten tensor $P$ to be constant is a generalisation of the Yamabe problem. On compact Riemannian n-manifolds we show that, for k between and including 3 and n, this prescription equation is an Euler-Lagrange equation of some act…

AdaptiveNet tackles disease progression prediction in rheumatoid arthritis using deep neural networks.

Study proves curvature prescription on spheres for k ≥ n/2.

In this paper we give a new proof of a theorem by Alexandrov on the Gauss curvature prescription of Euclidean convex sets. This proof is based on the duality theory of convex sets and on optimal mass transport. A noteworthy property of this proof is that it does not rely neither on the theory of convex polyhedra nor on…

This paper presents an automated approach for interpretable feature recommendation for solving signal data analytics problems. The method has been tested by performing experiments on datasets in the domain of prognostics where interpretation of features is considered very important. The proposed approach is based on Wi…

Two problems concerning asymptotically hyperbolic manifolds with an inner boundary are studied. First, we study scalar curvature presciption with either Dirichlet or mean curvature prescription interior boundary condition. Then we apply those results to the Lichnerowicz equation with (future or past) apparent horizon i…

In this paper, we study conformal invariants that arise from nodal sets and negative eigenvalues of conformally covariant operators; more specifically, the GJMS operators, which include the Yamabe and Paneitz operators. We give several applications to curvature prescription problems. We establish a version in conformal…

This work tackles maintenance planning with deep reinforcement learning under uncertainty.

For any compact manifold of dimension n>=5, we prescribe the volume and any finite part of the spectrum of the Hodge Laplacian acting on diffential forms of degree 1<p<n-1 (exept for p=n/2 if n is even), within a given conformal class. When n<5 and when p=0,1,n-1,n, and p=n/2 if n is even, this simultaneous prescriptio…

We develop a prediction-based prescriptive model for learning optimal personalized treatments for patients based on their Electronic Health Records (EHRs). Our approach consists of: (i) predicting future outcomes under each possible therapy using a robustified nonlinear model, and (ii) adopting a randomized prescriptiv…

Deep neural network (DNN) based approaches hold significant potential for reinforcement learning (RL) and have already shown remarkable gains over state-of-art methods in a number of applications. The effectiveness of DNN methods can be attributed to leveraging the abundance of supervised data to learn value functions,…

Deep learning predicts opioid use disorder risk in patients.

Paper proposes a method to quantify and explain machine learning uncertainty in predictive process monitoring.

Laboratory testing and medication prescription are two of the most important routines in daily clinical practice. Developing an artificial intelligence system that can automatically make lab test imputations and medication recommendations can save costs on potentially redundant lab tests and inform physicians of a more…

We prove that, for a generic set of smooth prescription functions $h$ on a closed ambient manifold, there always exists a nontrivial, smooth, closed hypersurface of prescribed mean curvature $h$. The solution is either an embedded minimal hypersurface with integer multiplicity, or a non-minimal almost embedded hypersur…

We prove existence of compact spacelike hypersurfaces with prescribed k - curvature in de Sitter space, where the prescription function depends on both space and the tilt function.

This research explores new optimization methods for training large neural networks.

Solves curvature prescription on rotational surfaces.

We extend our studies of a quantum field model defined on a lattice having the dilation group as a local gauge symmetry. The model is relevant in the cross-disciplinary area of econophysics. A corresponding proposal by Ilinski aimed at gauge modeling in non-equilibrium pricing is realized as a numerical simulation of t…

Hebbian learning derived from maximum entropy principles.

This paper considers the problems of modeling and predicting a long-term and ``blurry'' relapse that occurs after a medical act, such as a surgery. The relapse is observed only indirectly, in a ``blurry'' fashion, through longitudinal prescriptions of drugs over a long period of time after the medical act. We introduce…

Let $M$ be an open Riemann surface and $n\ge 3$ be an integer. We prove that on any closed discrete subset of $M$ one can prescribe the values of a conformal minimal immersion $M\to\mathbb{R}^n$. Our result also ensures jet-interpolation of given finite order, and hence, in particular, one may in addition prescribe the…

In this paper, we combine ideas from machine learning (ML) and operations research and management science (OR/MS) in developing a framework, along with specific methods, for using data to prescribe optimal decisions in OR/MS problems. In a departure from other work on data-driven optimization and reflecting our practic…

In this paper it is hown that given any smooth, positive function f on a closed, smooth manifold of dimension greater than four and with positive Paneitz invariant, there exists a metric on M such that $Q_g$ = f.

Optimizes decisions without knowing the true distribution using historical data.

The treatment effects of medications play a key role in guiding medical prescriptions. They are usually assessed with randomized controlled trials (RCTs), which are expensive. Recently, large-scale electronic health records (EHRs) have become available, opening up new opportunities for more cost-effective assessments. …

The paper solves curvature prescription on a disk with negative Gaussian curvature.